JP2011526920A5 - - Google Patents
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- Publication number
- JP2011526920A5 JP2011526920A5 JP2011516843A JP2011516843A JP2011526920A5 JP 2011526920 A5 JP2011526920 A5 JP 2011526920A5 JP 2011516843 A JP2011516843 A JP 2011516843A JP 2011516843 A JP2011516843 A JP 2011516843A JP 2011526920 A5 JP2011526920 A5 JP 2011526920A5
- Authority
- JP
- Japan
- Prior art keywords
- lysin
- chimeric
- peptide
- seq
- bacteriophage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7827708P | 2008-07-03 | 2008-07-03 | |
| US61/078,277 | 2008-07-03 | ||
| PCT/US2009/049349 WO2010002959A2 (en) | 2008-07-03 | 2009-07-01 | A chimeric bacteriophage lysin with activity against staphylococci bacteria |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015033626A Division JP6169632B2 (ja) | 2008-07-03 | 2015-02-24 | Ｓｔａｐｈｙｌｏｃｏｃｃｉｂａｃｔｅｒｉａに対する活性を有するキメラバクテリオファージ溶解素 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011526920A JP2011526920A (ja) | 2011-10-20 |
| JP2011526920A5 true JP2011526920A5 (https=) | 2012-08-16 |
| JP5758291B2 JP5758291B2 (ja) | 2015-08-05 |
Family
ID=41466590
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011516843A Expired - Fee Related JP5758291B2 (ja) | 2008-07-03 | 2009-07-01 | Ｓｔａｐｈｙｌｏｃｏｃｃｉｂａｃｔｅｒｉａに対する活性を有するキメラバクテリオファージ溶解素 |
| JP2015033626A Expired - Fee Related JP6169632B2 (ja) | 2008-07-03 | 2015-02-24 | Ｓｔａｐｈｙｌｏｃｏｃｃｉｂａｃｔｅｒｉａに対する活性を有するキメラバクテリオファージ溶解素 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015033626A Expired - Fee Related JP6169632B2 (ja) | 2008-07-03 | 2015-02-24 | Ｓｔａｐｈｙｌｏｃｏｃｃｉｂａｃｔｅｒｉａに対する活性を有するキメラバクテリオファージ溶解素 |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US8840900B2 (https=) |
| EP (2) | EP2307557B1 (https=) |
| JP (2) | JP5758291B2 (https=) |
| AU (2) | AU2009266982B2 (https=) |
| CA (2) | CA2729160C (https=) |
| ES (1) | ES2627321T3 (https=) |
| HK (1) | HK1248722A1 (https=) |
| WO (1) | WO2010002959A2 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8389469B2 (en) | 2005-06-06 | 2013-03-05 | The Rockefeller University | Bacteriophage lysins for Bacillus anthracis |
| EP2360248A1 (en) | 2005-08-24 | 2011-08-24 | The Rockefeller University | Ply-GBS mutant lysins |
| DK2699253T3 (en) | 2011-04-21 | 2018-07-16 | Univ Rockefeller | STREPTOCOCCUS BACTERYPHAGIC LYSINES FOR THE DETECTION AND TREATMENT OF GRAM POSITIVE BACTERIES |
| DK3085777T3 (da) * | 2011-05-04 | 2020-02-03 | Micreos Human Health Bv | Polypeptid |
| US9279118B2 (en) | 2011-10-05 | 2016-03-08 | The Rockefeller University | Dimeric bacteriophage lysins |
| RU2018121290A (ru) | 2012-05-09 | 2019-03-06 | Контрафект Корпорейшн | Комбинации лизина бактериофага и антибиотика против грам-положительных бактерий |
| BR112014027818B1 (pt) * | 2012-05-09 | 2023-03-28 | Contrafect Corporation | Usos de composições compreendendo polipeptídeo de lisina para prevenção, ruptura ou tratamento de um biofilme bacteriano |
| CN103122347B (zh) * | 2013-02-01 | 2015-04-22 | 中国科学院武汉病毒研究所 | 一种杀灭葡萄球菌的裂解酶及其应用 |
| ES2525954B1 (es) * | 2013-05-28 | 2015-10-23 | Consejo Superior De Investigaciones Científicas (Csic) | Enzibióticos bactericidas mejorados frente a neumococo y otras bacterias |
| CN104762285B (zh) * | 2015-04-23 | 2017-10-27 | 武汉菲吉乐科生物科技有限公司 | 一种自内裂解大肠杆菌的裂解酶及其应用 |
| CN104805066B (zh) * | 2015-05-18 | 2018-04-24 | 武汉菲吉乐科生物科技有限公司 | 一种葡萄球菌裂解酶及其应用 |
| EP3454888B1 (en) | 2016-05-12 | 2021-02-24 | Contrafect Corporation | Broth microdilution method for evaluating and determining minimal inhibitory concentration of antibacterial polypeptides |
| BR112020026267A2 (pt) * | 2018-06-22 | 2021-04-06 | Contrafect Corporation | Lisinas e seus derivados resensibilizam novamente staphylococcus aureus e bactérias gram-positivas aos antibióticos |
| WO2020032232A1 (ja) * | 2018-08-10 | 2020-02-13 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | バクテリオファージ剤 |
| CN109666667A (zh) * | 2019-01-22 | 2019-04-23 | 上海交通大学 | 杀灭金黄色葡萄球菌的嵌合酶抗生素及其制备和应用 |
| WO2021084558A2 (en) * | 2019-10-31 | 2021-05-06 | Bactoclear Holdings Pte. Ltd | Chimeric proteins for selective lysis of bacteria |
| WO2021178968A1 (en) * | 2020-03-06 | 2021-09-10 | Endolytix Technology, Inc. | Compositions and methods for the treatment of intracellular bacterial infections |
| WO2021180892A1 (en) * | 2020-03-11 | 2021-09-16 | Telum Therapeutics S.L. | New recombinant lysin and its use in the treatment of gram-negative bacterial infections |
| CN111808837A (zh) * | 2020-07-17 | 2020-10-23 | 青岛诺安百特生物技术有限公司 | 一种金黄色葡萄球菌噬菌体裂解酶及其制备方法和应用 |
| CN115820616A (zh) * | 2022-07-22 | 2023-03-21 | 昆明理工大学 | 一种带荧光标记的噬菌体裂解酶及其应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997008553A1 (en) * | 1995-08-22 | 1997-03-06 | The Regents Of The University Of California | Targeting of proteins to the cell wall of gram-positive bacteria |
| US6056954A (en) * | 1997-10-31 | 2000-05-02 | New Horizons Diagnostics Corp | Use of bacterial phage associated lysing enzymers for the prophylactic and therapeutic treatment of various illnesses |
| US6703025B1 (en) * | 1998-08-31 | 2004-03-09 | Inhibitex, Inc. | Multicomponent vaccines |
| US20020127215A1 (en) * | 1999-09-14 | 2002-09-12 | Lawrence Loomis | Parenteral use of bacterial phage associated lysing enzymes for the therapeutic treatment of bacterial infections |
| GB0107661D0 (en) * | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
| US20040213765A1 (en) * | 2001-07-13 | 2004-10-28 | Vincent Fischetti | Use of bacterial phage associated lytic enzymes to prevent food poisoning |
| EP1504088B1 (en) * | 2002-03-25 | 2007-08-15 | University Of Warwick | Bacteriophages useful for therapy and prophylaxis of bacterial infections |
| JPWO2004020635A1 (ja) * | 2002-08-28 | 2005-12-15 | 株式会社テクノネットワーク四国 | バクテリオファージおよび細菌感染症治療剤 |
| EP2360248A1 (en) * | 2005-08-24 | 2011-08-24 | The Rockefeller University | Ply-GBS mutant lysins |
| WO2009024327A2 (en) | 2007-08-22 | 2009-02-26 | Profos Ag | New proteins for use in human and animal staphylococcus infections |
| US8563504B2 (en) * | 2008-10-10 | 2013-10-22 | Lusomedicamenta, S.A. | Antibacterial phage peptides and methods of use thereof |
| AU2010211456B2 (en) * | 2009-02-06 | 2016-05-26 | Technophage, Investigação E Desenvolvimento Em Biotecnologia, S.A. | Antibacterial phage, phage peptides and methods of use thereof |
-
2009
- 2009-07-01 WO PCT/US2009/049349 patent/WO2010002959A2/en not_active Ceased
- 2009-07-01 CA CA2729160A patent/CA2729160C/en active Active
- 2009-07-01 JP JP2011516843A patent/JP5758291B2/ja not_active Expired - Fee Related
- 2009-07-01 EP EP09774409.8A patent/EP2307557B1/en active Active
- 2009-07-01 CA CA2984933A patent/CA2984933C/en active Active
- 2009-07-01 US US13/502,912 patent/US8840900B2/en active Active
- 2009-07-01 AU AU2009266982A patent/AU2009266982B2/en not_active Ceased
- 2009-07-01 ES ES09774409.8T patent/ES2627321T3/es active Active
- 2009-07-01 EP EP17158578.9A patent/EP3263588A1/en not_active Withdrawn
-
2014
- 2014-09-09 US US14/480,822 patent/US10053681B2/en active Active
-
2015
- 2015-02-24 JP JP2015033626A patent/JP6169632B2/ja not_active Expired - Fee Related
- 2015-09-25 AU AU2015230807A patent/AU2015230807B2/en not_active Ceased
-
2018
- 2018-06-27 HK HK18108284.8A patent/HK1248722A1/en unknown
- 2018-08-20 US US16/105,155 patent/US11015182B2/en active Active
-
2021
- 2021-05-24 US US17/328,299 patent/US11827911B2/en active Active
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