AU2009266982B2 - A chimeric bacteriophage lysin with activity against staphylococci bacteria - Google Patents
A chimeric bacteriophage lysin with activity against staphylococci bacteria Download PDFInfo
- Publication number
- AU2009266982B2 AU2009266982B2 AU2009266982A AU2009266982A AU2009266982B2 AU 2009266982 B2 AU2009266982 B2 AU 2009266982B2 AU 2009266982 A AU2009266982 A AU 2009266982A AU 2009266982 A AU2009266982 A AU 2009266982A AU 2009266982 B2 AU2009266982 B2 AU 2009266982B2
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- Australia
- Prior art keywords
- lysin
- bacteriophage lysin
- chimeric
- chimeric bacteriophage
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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| AU2015230807A AU2015230807B2 (en) | 2008-07-03 | 2015-09-25 | A chimeric bacteriophage lysin with activity against staphylococci bacteria |
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| PCT/US2009/049349 WO2010002959A2 (en) | 2008-07-03 | 2009-07-01 | A chimeric bacteriophage lysin with activity against staphylococci bacteria |
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| AU2015230807A Division AU2015230807B2 (en) | 2008-07-03 | 2015-09-25 | A chimeric bacteriophage lysin with activity against staphylococci bacteria |
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| AU2009266982A1 AU2009266982A1 (en) | 2010-01-07 |
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| US8389469B2 (en) | 2005-06-06 | 2013-03-05 | The Rockefeller University | Bacteriophage lysins for Bacillus anthracis |
| EP2360248A1 (en) | 2005-08-24 | 2011-08-24 | The Rockefeller University | Ply-GBS mutant lysins |
| DK2699253T3 (en) | 2011-04-21 | 2018-07-16 | Univ Rockefeller | STREPTOCOCCUS BACTERYPHAGIC LYSINES FOR THE DETECTION AND TREATMENT OF GRAM POSITIVE BACTERIES |
| DK3085777T3 (da) * | 2011-05-04 | 2020-02-03 | Micreos Human Health Bv | Polypeptid |
| US9279118B2 (en) | 2011-10-05 | 2016-03-08 | The Rockefeller University | Dimeric bacteriophage lysins |
| RU2018121290A (ru) | 2012-05-09 | 2019-03-06 | Контрафект Корпорейшн | Комбинации лизина бактериофага и антибиотика против грам-положительных бактерий |
| BR112014027818B1 (pt) * | 2012-05-09 | 2023-03-28 | Contrafect Corporation | Usos de composições compreendendo polipeptídeo de lisina para prevenção, ruptura ou tratamento de um biofilme bacteriano |
| CN103122347B (zh) * | 2013-02-01 | 2015-04-22 | 中国科学院武汉病毒研究所 | 一种杀灭葡萄球菌的裂解酶及其应用 |
| ES2525954B1 (es) * | 2013-05-28 | 2015-10-23 | Consejo Superior De Investigaciones Científicas (Csic) | Enzibióticos bactericidas mejorados frente a neumococo y otras bacterias |
| CN104762285B (zh) * | 2015-04-23 | 2017-10-27 | 武汉菲吉乐科生物科技有限公司 | 一种自内裂解大肠杆菌的裂解酶及其应用 |
| CN104805066B (zh) * | 2015-05-18 | 2018-04-24 | 武汉菲吉乐科生物科技有限公司 | 一种葡萄球菌裂解酶及其应用 |
| EP3454888B1 (en) | 2016-05-12 | 2021-02-24 | Contrafect Corporation | Broth microdilution method for evaluating and determining minimal inhibitory concentration of antibacterial polypeptides |
| BR112020026267A2 (pt) * | 2018-06-22 | 2021-04-06 | Contrafect Corporation | Lisinas e seus derivados resensibilizam novamente staphylococcus aureus e bactérias gram-positivas aos antibióticos |
| WO2020032232A1 (ja) * | 2018-08-10 | 2020-02-13 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | バクテリオファージ剤 |
| CN109666667A (zh) * | 2019-01-22 | 2019-04-23 | 上海交通大学 | 杀灭金黄色葡萄球菌的嵌合酶抗生素及其制备和应用 |
| WO2021084558A2 (en) * | 2019-10-31 | 2021-05-06 | Bactoclear Holdings Pte. Ltd | Chimeric proteins for selective lysis of bacteria |
| WO2021178968A1 (en) * | 2020-03-06 | 2021-09-10 | Endolytix Technology, Inc. | Compositions and methods for the treatment of intracellular bacterial infections |
| WO2021180892A1 (en) * | 2020-03-11 | 2021-09-16 | Telum Therapeutics S.L. | New recombinant lysin and its use in the treatment of gram-negative bacterial infections |
| CN111808837A (zh) * | 2020-07-17 | 2020-10-23 | 青岛诺安百特生物技术有限公司 | 一种金黄色葡萄球菌噬菌体裂解酶及其制备方法和应用 |
| CN115820616A (zh) * | 2022-07-22 | 2023-03-21 | 昆明理工大学 | 一种带荧光标记的噬菌体裂解酶及其应用 |
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| WO2009024327A2 (en) * | 2007-08-22 | 2009-02-26 | Profos Ag | New proteins for use in human and animal staphylococcus infections |
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| WO1997008553A1 (en) * | 1995-08-22 | 1997-03-06 | The Regents Of The University Of California | Targeting of proteins to the cell wall of gram-positive bacteria |
| US6056954A (en) * | 1997-10-31 | 2000-05-02 | New Horizons Diagnostics Corp | Use of bacterial phage associated lysing enzymers for the prophylactic and therapeutic treatment of various illnesses |
| US6703025B1 (en) * | 1998-08-31 | 2004-03-09 | Inhibitex, Inc. | Multicomponent vaccines |
| US20020127215A1 (en) * | 1999-09-14 | 2002-09-12 | Lawrence Loomis | Parenteral use of bacterial phage associated lysing enzymes for the therapeutic treatment of bacterial infections |
| GB0107661D0 (en) * | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
| US20040213765A1 (en) * | 2001-07-13 | 2004-10-28 | Vincent Fischetti | Use of bacterial phage associated lytic enzymes to prevent food poisoning |
| EP1504088B1 (en) * | 2002-03-25 | 2007-08-15 | University Of Warwick | Bacteriophages useful for therapy and prophylaxis of bacterial infections |
| JPWO2004020635A1 (ja) * | 2002-08-28 | 2005-12-15 | 株式会社テクノネットワーク四国 | バクテリオファージおよび細菌感染症治療剤 |
| EP2360248A1 (en) * | 2005-08-24 | 2011-08-24 | The Rockefeller University | Ply-GBS mutant lysins |
| US8563504B2 (en) * | 2008-10-10 | 2013-10-22 | Lusomedicamenta, S.A. | Antibacterial phage peptides and methods of use thereof |
| AU2010211456B2 (en) * | 2009-02-06 | 2016-05-26 | Technophage, Investigação E Desenvolvimento Em Biotecnologia, S.A. | Antibacterial phage, phage peptides and methods of use thereof |
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Patent Citations (1)
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| WO2009024327A2 (en) * | 2007-08-22 | 2009-02-26 | Profos Ag | New proteins for use in human and animal staphylococcus infections |
Non-Patent Citations (1)
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| D2 : RASHEL ET AL: "Efficient elimination of mutltidrug-resitant Staphylococcus aureus by cloned lysin derived from bacetriophage oMR11". Journal of Infectious Diseases, 2007, vol. 196, no. 8, pages 1237- 1247 * |
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| EP2307557A4 (en) | 2012-04-11 |
| US8840900B2 (en) | 2014-09-23 |
| AU2009266982A1 (en) | 2010-01-07 |
| AU2015230807B2 (en) | 2017-07-27 |
| JP5758291B2 (ja) | 2015-08-05 |
| CA2729160A1 (en) | 2010-01-07 |
| US11015182B2 (en) | 2021-05-25 |
| WO2010002959A2 (en) | 2010-01-07 |
| EP3263588A1 (en) | 2018-01-03 |
| US20190055533A1 (en) | 2019-02-21 |
| JP2011526920A (ja) | 2011-10-20 |
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| US20150064156A1 (en) | 2015-03-05 |
| ES2627321T3 (es) | 2017-07-27 |
| CA2729160C (en) | 2017-11-14 |
| JP2015126738A (ja) | 2015-07-09 |
| US20120258088A1 (en) | 2012-10-11 |
| JP6169632B2 (ja) | 2017-07-26 |
| CA2984933C (en) | 2020-07-07 |
| US11827911B2 (en) | 2023-11-28 |
| EP2307557B1 (en) | 2017-03-01 |
| HK1248722A1 (en) | 2018-10-19 |
| WO2010002959A3 (en) | 2010-05-06 |
| AU2015230807A1 (en) | 2015-10-15 |
| CA2984933A1 (en) | 2010-01-07 |
| EP2307557A2 (en) | 2011-04-13 |
| US20210348146A1 (en) | 2021-11-11 |
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