ES2627321T3 - Una lisina de bacteriófago quimérica con actividad contra bacterias estafilocócicas - Google Patents
Una lisina de bacteriófago quimérica con actividad contra bacterias estafilocócicas Download PDFInfo
- Publication number
- ES2627321T3 ES2627321T3 ES09774409.8T ES09774409T ES2627321T3 ES 2627321 T3 ES2627321 T3 ES 2627321T3 ES 09774409 T ES09774409 T ES 09774409T ES 2627321 T3 ES2627321 T3 ES 2627321T3
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10311—Siphoviridae
- C12N2795/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7827708P | 2008-07-03 | 2008-07-03 | |
| US78277P | 2008-07-03 | ||
| PCT/US2009/049349 WO2010002959A2 (en) | 2008-07-03 | 2009-07-01 | A chimeric bacteriophage lysin with activity against staphylococci bacteria |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2627321T3 true ES2627321T3 (es) | 2017-07-27 |
Family
ID=41466590
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09774409.8T Active ES2627321T3 (es) | 2008-07-03 | 2009-07-01 | Una lisina de bacteriófago quimérica con actividad contra bacterias estafilocócicas |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US8840900B2 (https=) |
| EP (2) | EP3263588A1 (https=) |
| JP (2) | JP5758291B2 (https=) |
| AU (2) | AU2009266982B2 (https=) |
| CA (2) | CA2984933C (https=) |
| ES (1) | ES2627321T3 (https=) |
| HK (1) | HK1248722A1 (https=) |
| WO (1) | WO2010002959A2 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008018854A2 (en) | 2005-06-06 | 2008-02-14 | The Rockefeller University | Bactiophage lysins for bacillus anthracis |
| CA2620903A1 (en) | 2005-08-24 | 2007-03-01 | The Rockefeller University | Ply-gbs mutant lysins |
| CA2833409A1 (en) | 2011-04-21 | 2012-10-26 | The Rockefeller University | Streptococcus bacteriophage lysins for detection and treatment of gram positive bacteria |
| CN103703127A (zh) | 2011-05-04 | 2014-04-02 | 迈克瑞欧斯人体健康有限公司 | 一种多肽 |
| EP2764093B1 (en) | 2011-10-05 | 2018-04-18 | The Rockefeller University | Dimeric bacteriophage lysins |
| KR20210121313A (ko) * | 2012-05-09 | 2021-10-07 | 콘트라펙트 코포레이션 | 그람 양성 박테리아에 대한 박테리오파지 리신과 항생제의 병용물 |
| KR20200023521A (ko) * | 2012-05-09 | 2020-03-04 | 콘트라펙트 코포레이션 | 박테리오파지 리신을 이용한 생물막의 예방, 붕괴 및 치료 |
| CN103122347B (zh) * | 2013-02-01 | 2015-04-22 | 中国科学院武汉病毒研究所 | 一种杀灭葡萄球菌的裂解酶及其应用 |
| ES2525954B1 (es) * | 2013-05-28 | 2015-10-23 | Consejo Superior De Investigaciones Científicas (Csic) | Enzibióticos bactericidas mejorados frente a neumococo y otras bacterias |
| CN104762285B (zh) * | 2015-04-23 | 2017-10-27 | 武汉菲吉乐科生物科技有限公司 | 一种自内裂解大肠杆菌的裂解酶及其应用 |
| CN104805066B (zh) * | 2015-05-18 | 2018-04-24 | 武汉菲吉乐科生物科技有限公司 | 一种葡萄球菌裂解酶及其应用 |
| KR20190004799A (ko) | 2016-05-12 | 2019-01-14 | 콘트라펙트 코포레이션 | 항균 폴리펩티드의 최소 억제 농도를 평가 및 탐지하기 위한 배지미량희석법 |
| CN112867398A (zh) * | 2018-06-22 | 2021-05-28 | 康特拉费克特公司 | 溶素及其衍生物使金黄色葡萄球菌和革兰氏阳性菌对抗生素重新敏感 |
| CN113038960A (zh) * | 2018-08-10 | 2021-06-25 | 明治制果药业株式会社 | 噬菌体剂 |
| CN109666667A (zh) * | 2019-01-22 | 2019-04-23 | 上海交通大学 | 杀灭金黄色葡萄球菌的嵌合酶抗生素及其制备和应用 |
| JP2023510074A (ja) * | 2019-10-31 | 2023-03-13 | バクトクリア ホールディングス ピーティーイー エルティーディー． | 細菌の選択的溶解のためのキメラタンパク質 |
| WO2021178968A1 (en) * | 2020-03-06 | 2021-09-10 | Endolytix Technology, Inc. | Compositions and methods for the treatment of intracellular bacterial infections |
| MX2022011291A (es) * | 2020-03-11 | 2022-12-08 | Telum Therapeutics S L | Nueva lisina recombinante y su uso en el tratamiento de infecciones por bacterias gramnegativas. |
| CN111808837A (zh) * | 2020-07-17 | 2020-10-23 | 青岛诺安百特生物技术有限公司 | 一种金黄色葡萄球菌噬菌体裂解酶及其制备方法和应用 |
| CN115820616A (zh) * | 2022-07-22 | 2023-03-21 | 昆明理工大学 | 一种带荧光标记的噬菌体裂解酶及其应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997008553A1 (en) * | 1995-08-22 | 1997-03-06 | The Regents Of The University Of California | Targeting of proteins to the cell wall of gram-positive bacteria |
| US6056954A (en) * | 1997-10-31 | 2000-05-02 | New Horizons Diagnostics Corp | Use of bacterial phage associated lysing enzymers for the prophylactic and therapeutic treatment of various illnesses |
| US6703025B1 (en) * | 1998-08-31 | 2004-03-09 | Inhibitex, Inc. | Multicomponent vaccines |
| US20020127215A1 (en) | 1999-09-14 | 2002-09-12 | Lawrence Loomis | Parenteral use of bacterial phage associated lysing enzymes for the therapeutic treatment of bacterial infections |
| GB0107661D0 (en) * | 2001-03-27 | 2001-05-16 | Chiron Spa | Staphylococcus aureus |
| US20040213765A1 (en) | 2001-07-13 | 2004-10-28 | Vincent Fischetti | Use of bacterial phage associated lytic enzymes to prevent food poisoning |
| DE60315636T2 (de) * | 2002-03-25 | 2008-05-08 | University Of Warwick, Coventry | Zur therapie und prophylaxe bakterieller infektionen geeignete bakteriophagen |
| JPWO2004020635A1 (ja) * | 2002-08-28 | 2005-12-15 | 株式会社テクノネットワーク四国 | バクテリオファージおよび細菌感染症治療剤 |
| CA2620903A1 (en) * | 2005-08-24 | 2007-03-01 | The Rockefeller University | Ply-gbs mutant lysins |
| DK2185699T3 (en) * | 2007-08-22 | 2018-01-22 | Hyglos Invest Gmbh | NEW PROTEINS FOR USE IN STAPHYLOCOCCUS INFECTIONS IN HUMAN AND ANIMALS |
| CA2739717A1 (en) * | 2008-10-10 | 2010-04-15 | Lusomedicamenta, S.A. | Antibacterial phage peptides and methods of use thereof |
| JP5701777B2 (ja) * | 2009-02-06 | 2015-04-15 | テクノファージ， インベスティガサン エ デセンボルビメント エム ビオテクノロジア，エスエー | 抗菌性ファージ、ファージペプチド、及びそれらの使用方法 |
-
2009
- 2009-07-01 EP EP17158578.9A patent/EP3263588A1/en not_active Withdrawn
- 2009-07-01 CA CA2984933A patent/CA2984933C/en active Active
- 2009-07-01 EP EP09774409.8A patent/EP2307557B1/en active Active
- 2009-07-01 WO PCT/US2009/049349 patent/WO2010002959A2/en not_active Ceased
- 2009-07-01 JP JP2011516843A patent/JP5758291B2/ja not_active Expired - Fee Related
- 2009-07-01 CA CA2729160A patent/CA2729160C/en active Active
- 2009-07-01 AU AU2009266982A patent/AU2009266982B2/en not_active Ceased
- 2009-07-01 ES ES09774409.8T patent/ES2627321T3/es active Active
- 2009-07-01 US US13/502,912 patent/US8840900B2/en active Active
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2014
- 2014-09-09 US US14/480,822 patent/US10053681B2/en active Active
-
2015
- 2015-02-24 JP JP2015033626A patent/JP6169632B2/ja not_active Expired - Fee Related
- 2015-09-25 AU AU2015230807A patent/AU2015230807B2/en not_active Ceased
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2018
- 2018-06-27 HK HK18108284.8A patent/HK1248722A1/en unknown
- 2018-08-20 US US16/105,155 patent/US11015182B2/en active Active
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2021
- 2021-05-24 US US17/328,299 patent/US11827911B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20150064156A1 (en) | 2015-03-05 |
| AU2015230807B2 (en) | 2017-07-27 |
| EP2307557A4 (en) | 2012-04-11 |
| US20210348146A1 (en) | 2021-11-11 |
| AU2009266982B2 (en) | 2015-06-25 |
| JP2011526920A (ja) | 2011-10-20 |
| US10053681B2 (en) | 2018-08-21 |
| WO2010002959A2 (en) | 2010-01-07 |
| US11015182B2 (en) | 2021-05-25 |
| CA2984933C (en) | 2020-07-07 |
| US20120258088A1 (en) | 2012-10-11 |
| US8840900B2 (en) | 2014-09-23 |
| AU2009266982A1 (en) | 2010-01-07 |
| CA2729160C (en) | 2017-11-14 |
| EP3263588A1 (en) | 2018-01-03 |
| WO2010002959A3 (en) | 2010-05-06 |
| HK1248722A1 (en) | 2018-10-19 |
| AU2015230807A1 (en) | 2015-10-15 |
| US20190055533A1 (en) | 2019-02-21 |
| JP5758291B2 (ja) | 2015-08-05 |
| CA2984933A1 (en) | 2010-01-07 |
| EP2307557A2 (en) | 2011-04-13 |
| JP6169632B2 (ja) | 2017-07-26 |
| EP2307557B1 (en) | 2017-03-01 |
| CA2729160A1 (en) | 2010-01-07 |
| JP2015126738A (ja) | 2015-07-09 |
| US11827911B2 (en) | 2023-11-28 |
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