JP2011522023A5 - - Google Patents

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Publication number
JP2011522023A5
JP2011522023A5 JP2011512213A JP2011512213A JP2011522023A5 JP 2011522023 A5 JP2011522023 A5 JP 2011522023A5 JP 2011512213 A JP2011512213 A JP 2011512213A JP 2011512213 A JP2011512213 A JP 2011512213A JP 2011522023 A5 JP2011522023 A5 JP 2011522023A5
Authority
JP
Japan
Prior art keywords
rasagiline
organic solvent
enantiomerically pure
pharmaceutically acceptable
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2011512213A
Other languages
English (en)
Japanese (ja)
Other versions
JP5487440B2 (ja
JP2011522023A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/GB2009/050608 external-priority patent/WO2009147430A1/en
Publication of JP2011522023A publication Critical patent/JP2011522023A/ja
Publication of JP2011522023A5 publication Critical patent/JP2011522023A5/ja
Application granted granted Critical
Publication of JP5487440B2 publication Critical patent/JP5487440B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2011512213A 2008-06-02 2009-06-02 鏡像異性的に純粋なアミンの調製方法 Expired - Fee Related JP5487440B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN973/KOL/2008 2008-06-02
IN973KO2008 2008-06-02
PCT/GB2009/050608 WO2009147430A1 (en) 2008-06-02 2009-06-02 A process for the preparation of enantiomerically pure amines

Publications (3)

Publication Number Publication Date
JP2011522023A JP2011522023A (ja) 2011-07-28
JP2011522023A5 true JP2011522023A5 (enExample) 2012-07-19
JP5487440B2 JP5487440B2 (ja) 2014-05-07

Family

ID=40874479

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011512213A Expired - Fee Related JP5487440B2 (ja) 2008-06-02 2009-06-02 鏡像異性的に純粋なアミンの調製方法

Country Status (10)

Country Link
US (2) US8569545B2 (enExample)
EP (1) EP2285769B1 (enExample)
JP (1) JP5487440B2 (enExample)
CN (2) CN103896779B (enExample)
AU (1) AU2009254927B2 (enExample)
CA (2) CA2723869C (enExample)
CY (1) CY1115577T1 (enExample)
NZ (1) NZ589486A (enExample)
PL (1) PL2285769T3 (enExample)
WO (1) WO2009147430A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009254927B2 (en) * 2008-06-02 2014-03-13 Generics [Uk] Limited A process for the preparation of enantiomerically pure amines
EP2681186B1 (en) 2011-03-03 2016-05-11 Synthon BV Process of resolution of 1-aminoindan
WO2015033261A1 (en) 2013-09-03 2015-03-12 Universidade De Évora Process for preparing cyclic chiral amines and alcohols by intramolecular catalytic arylation of boronic acid or ester aldehydes and imine substrates
CN104326920B (zh) * 2014-10-13 2016-03-16 江苏清泉化学股份有限公司 一种去除间苯二甲胺中杂质的方法
CN105018560B (zh) * 2015-08-13 2018-09-14 陈永军 动态动力学拆分制备(s)-6-甲氧基-1-氨基茚满
CN105063161B (zh) * 2015-08-18 2018-11-09 陈永军 一种r-1-氨基茚满的制备方法
CN105087742B (zh) * 2015-08-18 2018-09-14 陈永军 动态动力学拆分制备r-6-羟基-1-氨基茚满
CN105177103B (zh) * 2015-08-19 2019-03-12 陈永军 一种r-6-羟基-1-氨基茚满的制备方法
AR110150A1 (es) * 2016-11-09 2019-02-27 Roivant Sciences Gmbh Procesos para la preparación de inhibidores de tph1

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US3728388A (en) 1970-08-10 1973-04-17 Sterling Drug Inc 1-amino-2,3-disubstituted cyclopropenylium salts
US3855227A (en) * 1972-05-08 1974-12-17 C Hollander ({31 )-di-o-isopropylidene-2-keto-l-gulonates
US3912761A (en) 1972-05-08 1975-10-14 Hoffmann La Roche (-)-Di-O-isopropylidene-2-keto-L-gulonates
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HU187775B (en) 1982-07-14 1986-02-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu New process for producing propargile-amines of pharmaceutical activity
US4833273A (en) 1986-02-03 1989-05-23 Warner-Lambert Company Process for the resolution of 1-aminoindanes
AU607437B2 (en) 1986-09-02 1991-03-07 Du Pont Pharmaceuticals Company Resolution of dl-methyl 3-(4-(2-hydroxy-3-isopropylamino) propoxy)phenylpropionate((dl-esmolol))
CS269271B1 (en) 1988-05-30 1990-04-11 Hajicek Josef Method of selegiline's hydrochloride production
IL92952A (en) 1990-01-03 1994-06-24 Teva Pharma R-enantiomers of n-propargyl-1-aminoindan compounds, their preparation and pharmaceutical compositions containing them
US5744500A (en) 1990-01-03 1998-04-28 Teva Pharmaceutical Industries, Ltd. Use of R-enantiomer of N-propargyl-1-aminoindan, salts, and compositions thereof
US5030725A (en) 1990-02-06 1991-07-09 Eli Lilly And Company Method of resolving cis 3-amino-4-[2-(2-furyl)eth-1-yl]-1-methoxycarbonylmethyl-azetidin-2-one using (-)-DAG
CN1031995C (zh) 1991-01-02 1996-06-12 奥韦特有限公司 N-炔丙基-1-氨基茚满的r-对映体的制法
IL111240A (en) * 1993-10-18 2001-10-31 Teva Pharma Salts of r(+) - enantiomers of n- propargyl-1-aminoindan and pharmaceutical compositions comprising them
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EP0738149B1 (en) 1994-01-10 2006-11-29 Teva Pharmaceutical Industries, Ltd. 1-aminoindan derivatives and compositions thereof
JP2840560B2 (ja) 1994-11-22 1998-12-24 キノイン・ジヨージセル・エーシユ・ベジエーセテイ・テルメーケク・ジヤーラ・エル・テー 塩化プロパルギルアンモニウム誘導体の製造方法
IL141690A (en) * 2001-02-27 2004-06-20 Isp Finetech Ltd Process for preparation of rasagiline and its salts
AR044007A1 (es) * 2003-04-11 2005-08-24 Newron Pharmaceuticals Inc Metodos para el tratamiento de la enfermedad de parkinson
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JP2009521402A (ja) 2005-11-17 2009-06-04 テバ ファーマシューティカル インダストリーズ リミティド プロパルギル化アミノインダンの分離のための方法
CN101062897B (zh) 2006-04-25 2011-11-23 重庆医药工业研究院有限责任公司 一种制备2，3-二氢-1h-茚-1-胺及其衍生物的改进方法
RS52183B (sr) 2006-12-14 2012-10-31 Teva Pharmaceutical Industries, Ltd. Kristalna čvrsta baza razagilina
EP1987816A1 (de) 2007-04-30 2008-11-05 Ratiopharm GmbH Adsorbate eines Rasagilinsalzes mit einem wasserlöslichen Hilfsstoff
NZ589470A (en) 2008-06-02 2012-08-31 Generics Uk Ltd A process for the preparation of rasagiline and its analogues
AU2009254927B2 (en) * 2008-06-02 2014-03-13 Generics [Uk] Limited A process for the preparation of enantiomerically pure amines
WO2010013048A1 (en) 2008-07-30 2010-02-04 Generics [Uk] Limited Polymorphic form of rasagiline mesylate

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