JP2011520996A5 - - Google Patents
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- Publication number
- JP2011520996A5 JP2011520996A5 JP2011510855A JP2011510855A JP2011520996A5 JP 2011520996 A5 JP2011520996 A5 JP 2011520996A5 JP 2011510855 A JP2011510855 A JP 2011510855A JP 2011510855 A JP2011510855 A JP 2011510855A JP 2011520996 A5 JP2011520996 A5 JP 2011520996A5
- Authority
- JP
- Japan
- Prior art keywords
- leukemia
- acute
- chronic
- lymphocytic leukemia
- myeloid leukemia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010028980 Neoplasm Diseases 0.000 claims description 3
- 208000024893 Acute lymphoblastic leukemia Diseases 0.000 claims description 2
- 208000014697 Acute lymphocytic leukaemia Diseases 0.000 claims description 2
- 208000031261 Acute myeloid leukaemia Diseases 0.000 claims description 2
- 208000010839 B-cell chronic lymphocytic leukemia Diseases 0.000 claims description 2
- 208000032791 BCR-ABL1 positive chronic myelogenous leukemia Diseases 0.000 claims description 2
- 208000010833 Chronic myeloid leukaemia Diseases 0.000 claims description 2
- 208000031422 Lymphocytic Chronic B-Cell Leukemia Diseases 0.000 claims description 2
- 208000033761 Myelogenous Chronic BCR-ABL Positive Leukemia Diseases 0.000 claims description 2
- 208000033776 Myeloid Acute Leukemia Diseases 0.000 claims description 2
- 208000006664 Precursor Cell Lymphoblastic Leukemia-Lymphoma Diseases 0.000 claims description 2
- 208000032852 chronic lymphocytic leukemia Diseases 0.000 claims description 2
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102008025750.8 | 2008-05-29 | ||
| DE102008025750A DE102008025750A1 (de) | 2008-05-29 | 2008-05-29 | Dihydropyrazolderivate |
| PCT/EP2009/003030 WO2009143945A1 (de) | 2008-05-29 | 2009-04-24 | Dihydropyrazolderivate als tyrosinkinase modulatoren zur behandlung von tumoren |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011520996A JP2011520996A (ja) | 2011-07-21 |
| JP2011520996A5 true JP2011520996A5 (enExample) | 2014-05-08 |
| JP5643192B2 JP5643192B2 (ja) | 2014-12-17 |
Family
ID=40822993
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011510855A Expired - Fee Related JP5643192B2 (ja) | 2008-05-29 | 2009-04-24 | 腫瘍を処置するためのチロシンキナーゼモジュレーターとしてのジヒドロピラゾール誘導体 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US8404685B2 (enExample) |
| EP (1) | EP2300434B1 (enExample) |
| JP (1) | JP5643192B2 (enExample) |
| KR (1) | KR20110010821A (enExample) |
| CN (1) | CN102046605B (enExample) |
| AR (1) | AR071951A1 (enExample) |
| AU (1) | AU2009253432B2 (enExample) |
| BR (1) | BRPI0912970A2 (enExample) |
| CA (1) | CA2726009C (enExample) |
| DE (1) | DE102008025750A1 (enExample) |
| EA (1) | EA018394B1 (enExample) |
| ES (1) | ES2507573T3 (enExample) |
| IL (1) | IL209418A (enExample) |
| MX (1) | MX2010012804A (enExample) |
| WO (1) | WO2009143945A1 (enExample) |
| ZA (1) | ZA201009085B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2726463B1 (en) | 2011-07-01 | 2020-03-11 | Merck Patent GmbH | Dihydropyrazoles, pharmaceutical compositions thereof and their use for the treatment of fertility disorders |
| CA2878621C (en) * | 2012-07-10 | 2020-09-15 | Ares Trading S.A. | Pyrimidine pyrazolyl derivatives |
| EP3886854A4 (en) | 2018-11-30 | 2022-07-06 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
| BR9707495A (pt) | 1996-02-13 | 1999-07-27 | Zeneca Ltd | Derivado de quinazolina processo para a preparação do mesmo composição farmacêutica e processo para a produç o de um efeito antiangiogênico e/ou de redução de permeabilidade vascular em um animal de sangue quente |
| JP4464466B2 (ja) | 1996-03-05 | 2010-05-19 | アストラゼネカ・ユーケイ・リミテッド | ４―アニリノキナゾリン誘導体 |
| GB9718972D0 (en) | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
| GB9714249D0 (en) | 1997-07-08 | 1997-09-10 | Angiogene Pharm Ltd | Vascular damaging agents |
| GB9900334D0 (en) | 1999-01-07 | 1999-02-24 | Angiogene Pharm Ltd | Tricylic vascular damaging agents |
| GB9900752D0 (en) | 1999-01-15 | 1999-03-03 | Angiogene Pharm Ltd | Benzimidazole vascular damaging agents |
| IL152682A0 (en) | 2000-05-31 | 2003-06-24 | Astrazeneca Ab | Indole derivatives with vascular damaging activity |
| JP2004502766A (ja) | 2000-07-07 | 2004-01-29 | アンギオジェン・ファーマシューティカルズ・リミテッド | 血管損傷剤としてのコルヒノール誘導体 |
| CA2410562A1 (en) | 2000-07-07 | 2002-01-31 | Angiogene Pharmaceuticals Limited | Colchinol derivatives as angiogenesis inhibitors |
| AU2003249597B2 (en) | 2002-03-08 | 2007-06-28 | Merck Sharp & Dohme Corp. | Mitotic kinesin inhibitors |
| DE102005038537A1 (de) | 2005-08-16 | 2007-02-22 | Merck Patent Gmbh | 1-Acyldihydropyrazolderivate |
-
2008
- 2008-05-29 DE DE102008025750A patent/DE102008025750A1/de not_active Withdrawn
-
2009
- 2009-04-24 ES ES09753600.7T patent/ES2507573T3/es active Active
- 2009-04-24 BR BRPI0912970A patent/BRPI0912970A2/pt not_active IP Right Cessation
- 2009-04-24 US US12/993,892 patent/US8404685B2/en not_active Expired - Fee Related
- 2009-04-24 AU AU2009253432A patent/AU2009253432B2/en not_active Ceased
- 2009-04-24 MX MX2010012804A patent/MX2010012804A/es active IP Right Grant
- 2009-04-24 CN CN2009801192665A patent/CN102046605B/zh not_active Expired - Fee Related
- 2009-04-24 EA EA201001831A patent/EA018394B1/ru not_active IP Right Cessation
- 2009-04-24 EP EP09753600.7A patent/EP2300434B1/de not_active Not-in-force
- 2009-04-24 JP JP2011510855A patent/JP5643192B2/ja not_active Expired - Fee Related
- 2009-04-24 WO PCT/EP2009/003030 patent/WO2009143945A1/de not_active Ceased
- 2009-04-24 CA CA2726009A patent/CA2726009C/en active Active
- 2009-04-24 KR KR1020107029265A patent/KR20110010821A/ko not_active Ceased
- 2009-05-29 AR ARP090101932A patent/AR071951A1/es unknown
-
2010
- 2010-11-18 IL IL209418A patent/IL209418A/en active IP Right Grant
- 2010-12-17 ZA ZA2010/09085A patent/ZA201009085B/en unknown
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