JP2011519271A - エクスビボで制御性ｔ細胞の作成を加速するための方法および組成物 - Google Patents
エクスビボで制御性ｔ細胞の作成を加速するための方法および組成物 Download PDFInfo
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- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/416—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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| US4430608P | 2008-04-11 | 2008-04-11 | |
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| PCT/US2009/040190 WO2009126877A2 (en) | 2008-04-11 | 2009-04-10 | Methods and compositions for accelerating the generation of regulatory tcells ex vivo |
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| JP2011519271A true JP2011519271A (ja) | 2011-07-07 |
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| EP (1) | EP2281031A2 (enExample) |
| JP (1) | JP2011519271A (enExample) |
| CN (1) | CN102066557A (enExample) |
| AU (1) | AU2009234210A1 (enExample) |
| CA (1) | CA2721088A1 (enExample) |
| WO (1) | WO2009126877A2 (enExample) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012527237A (ja) * | 2009-05-18 | 2012-11-08 | セラコス・インコーポレイテッド | 免疫介在性疾患における臨床応用のための、抑制機能の高められた制御性ｔ細胞のエクスビボ増加方法 |
| JP2017505766A (ja) * | 2014-01-17 | 2017-02-23 | デベヴェ・テクノロジーズ | 皮膚上でのイムノリバランス |
| JP2018532414A (ja) * | 2015-10-28 | 2018-11-08 | ライフ テクノロジーズ エーエス | 細胞表面シグナル及びシグナル比を変えることによる、異なるｔ細胞亜集団の選択的増殖の方法 |
| WO2020040198A1 (ja) | 2018-08-22 | 2020-02-27 | 国立大学法人大阪大学 | 制御性ｔ細胞の作製法 |
| JP2024515334A (ja) * | 2021-05-25 | 2024-04-08 | 昭泰英基生物医薬（香港）有限公司 | Ｔ細胞をｎｋ様細胞にリプログラミングする誘導剤およびその使用 |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009155477A1 (en) | 2008-06-19 | 2009-12-23 | The Trustees Of The University Of Pennsylvania | Inducible regulatory t-cell generation for hematopoietic transplants |
| CN102971416B (zh) * | 2010-04-22 | 2018-03-30 | 南加州大学 | 用于扩增和稳定天然调节性t细胞的方法和组合物 |
| CN102321580A (zh) * | 2011-08-23 | 2012-01-18 | 郑颂国 | 一种治疗自体自身免疫性疾病的调节t细胞及其制备方法 |
| EP2968565A2 (en) | 2013-03-14 | 2016-01-20 | Genentech, Inc. | Methods of treating cancer and preventing cancer drug resistance |
| CN105597090B (zh) * | 2014-11-14 | 2022-08-23 | 中国科学院上海营养与健康研究所 | 一种提高cd4阳性t淋巴细胞存活率和活性的试剂及其应用 |
| US10905706B2 (en) | 2015-01-08 | 2021-02-02 | The Johns Hopkins University | Compositions and methods to accelerate resolution of acute lung inflammation |
| WO2017066561A2 (en) * | 2015-10-16 | 2017-04-20 | President And Fellows Of Harvard College | Regulatory t cell pd-1 modulation for regulating t cell effector immune responses |
| EP3551749B1 (en) | 2016-12-07 | 2023-09-27 | East Carolina University | Compositions and methods for in vitro cultivation and/or expansion of regulatory t cells |
| JP7142846B2 (ja) | 2017-01-30 | 2022-09-28 | 国立大学法人京都大学 | 新規化合物及び制御性ｔ細胞の製造方法 |
| CN108060129A (zh) * | 2017-12-11 | 2018-05-22 | 上海药明生物技术有限公司 | 调节性t细胞体外扩增方法 |
| US11975024B2 (en) * | 2017-12-19 | 2024-05-07 | Musc Foundation For Research Development | T regulatory (Treg) cell transplantation in osteogenesis imperfecta (OI) |
| US20210290742A1 (en) * | 2018-09-27 | 2021-09-23 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Methods of using lysine deacetylase (kdac) inhibition to generate antigen specific memory t cell responses for durable immunotherapy |
| JP2023527459A (ja) * | 2020-06-01 | 2023-06-28 | ザ ヘンリー エム． ジャクソン ファウンデーション フォー ザ アドヴァンスメント オブ ミリタリー メディシン インコーポレイテッド | 誘導性制御性ｔ細胞、その生成方法及び使用 |
| GB202008957D0 (en) * | 2020-06-12 | 2020-07-29 | Autolus Ltd | Culture medium |
| CN119592507A (zh) * | 2024-12-03 | 2025-03-11 | 哈尔滨优莱福生物科技有限公司 | 一种人外周血调节性t细胞的体外扩增试剂盒及其使用方法和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030157057A1 (en) * | 1999-05-05 | 2003-08-21 | Horwitz David A. | Methods for the induction of professional and cytokine-producing regulatory T cells |
| US20030147865A1 (en) * | 2002-02-07 | 2003-08-07 | Benoit Salomon | Cell therapy using immunoregulatory T-cells |
| US20100061984A1 (en) * | 2006-01-20 | 2010-03-11 | The Trustees Of The University Of Pennsylvania | Compositions and methods for modulation of suppressor t cell activation |
| ATE508207T1 (de) * | 2006-02-28 | 2011-05-15 | Charite Universitaetsmedizin | Nachweis und qualitätskontrolle von regulator-t- zellen mittels dna-methylierungsanalyse des foxp3-gens |
| JP2010531138A (ja) * | 2007-06-13 | 2010-09-24 | ラ ホヤ インスティテュート フォア アラージー アンド イムノロジー | 制御性ｔ細胞ならびに同製造および使用方法 |
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2009
- 2009-04-10 EP EP09729610A patent/EP2281031A2/en not_active Withdrawn
- 2009-04-10 AU AU2009234210A patent/AU2009234210A1/en not_active Abandoned
- 2009-04-10 JP JP2011504202A patent/JP2011519271A/ja not_active Withdrawn
- 2009-04-10 WO PCT/US2009/040190 patent/WO2009126877A2/en not_active Ceased
- 2009-04-10 CA CA2721088A patent/CA2721088A1/en not_active Abandoned
- 2009-04-10 US US12/421,941 patent/US20090257988A1/en not_active Abandoned
- 2009-04-10 CN CN2009801230830A patent/CN102066557A/zh active Pending
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012527237A (ja) * | 2009-05-18 | 2012-11-08 | セラコス・インコーポレイテッド | 免疫介在性疾患における臨床応用のための、抑制機能の高められた制御性ｔ細胞のエクスビボ増加方法 |
| JP2017505766A (ja) * | 2014-01-17 | 2017-02-23 | デベヴェ・テクノロジーズ | 皮膚上でのイムノリバランス |
| JP2018532414A (ja) * | 2015-10-28 | 2018-11-08 | ライフ テクノロジーズ エーエス | 細胞表面シグナル及びシグナル比を変えることによる、異なるｔ細胞亜集団の選択的増殖の方法 |
| JP7084304B2 (ja) | 2015-10-28 | 2022-06-14 | ライフ テクノロジーズ エーエス | 細胞表面シグナル及びシグナル比を変えることによる、異なるｔ細胞亜集団の選択的増殖の方法 |
| WO2020040198A1 (ja) | 2018-08-22 | 2020-02-27 | 国立大学法人大阪大学 | 制御性ｔ細胞の作製法 |
| JPWO2020040198A1 (ja) * | 2018-08-22 | 2021-08-10 | 国立大学法人大阪大学 | 制御性ｔ細胞の作製法 |
| JP7083190B2 (ja) | 2018-08-22 | 2022-06-10 | 国立大学法人大阪大学 | 制御性ｔ細胞の作製法 |
| JP2024515334A (ja) * | 2021-05-25 | 2024-04-08 | 昭泰英基生物医薬（香港）有限公司 | Ｔ細胞をｎｋ様細胞にリプログラミングする誘導剤およびその使用 |
| JP7828098B2 (ja) | 2021-05-25 | 2026-03-11 | 昭泰英基生物医薬（香港）有限公司 | Ｔ細胞をｎｋ様細胞にリプログラミングする誘導剤およびその使用 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2009234210A1 (en) | 2009-10-15 |
| EP2281031A2 (en) | 2011-02-09 |
| AU2009234210A2 (en) | 2010-12-16 |
| US20090257988A1 (en) | 2009-10-15 |
| CA2721088A1 (en) | 2009-10-15 |
| CN102066557A (zh) | 2011-05-18 |
| WO2009126877A2 (en) | 2009-10-15 |
| WO2009126877A3 (en) | 2009-12-03 |
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