JP2011518819A5 - - Google Patents
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- Publication number
- JP2011518819A5 JP2011518819A5 JP2011505593A JP2011505593A JP2011518819A5 JP 2011518819 A5 JP2011518819 A5 JP 2011518819A5 JP 2011505593 A JP2011505593 A JP 2011505593A JP 2011505593 A JP2011505593 A JP 2011505593A JP 2011518819 A5 JP2011518819 A5 JP 2011518819A5
- Authority
- JP
- Japan
- Prior art keywords
- independently
- nhr
- alkyl
- saturated aliphatic
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 0 CN*C([C@]1N=C(*)C(*)=C)C=CN=C1N Chemical compound CN*C([C@]1N=C(*)C(*)=C)C=CN=C1N 0.000 description 19
- CJHBCYQLRZBCJD-UHFFFAOYSA-N CC(C)(C)c1n[n](CC=C)c(NC(Nc(cc2)c3ncccc3c2Oc2ccnc(N3)c2N=CC3=O)=O)c1 Chemical compound CC(C)(C)c1n[n](CC=C)c(NC(Nc(cc2)c3ncccc3c2Oc2ccnc(N3)c2N=CC3=O)=O)c1 CJHBCYQLRZBCJD-UHFFFAOYSA-N 0.000 description 2
- BMJIPGXVDYVSGD-UHFFFAOYSA-N CC(C)(C)c(cc1NC(Nc(cc2)c(cccn3)c3c2Oc(ccnc2N3)c2NC3=O)=O)n[n]1-c1ccccc1 Chemical compound CC(C)(C)c(cc1NC(Nc(cc2)c(cccn3)c3c2Oc(ccnc2N3)c2NC3=O)=O)n[n]1-c1ccccc1 BMJIPGXVDYVSGD-UHFFFAOYSA-N 0.000 description 1
- DPBHAHWMWJKZGA-UHFFFAOYSA-N CC(C)(C)c(cc1NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N3)c2N=C(C)C3=O)=O)n[n]1-c1ccc(C)cc1 Chemical compound CC(C)(C)c(cc1NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N3)c2N=C(C)C3=O)=O)n[n]1-c1ccc(C)cc1 DPBHAHWMWJKZGA-UHFFFAOYSA-N 0.000 description 1
- ZCHGTAIGWVCOPK-UHFFFAOYSA-N CC(C)(C)c(cc1NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N3)c2N=CC3=O)=O)n[n]1-c1ccccc1 Chemical compound CC(C)(C)c(cc1NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N3)c2N=CC3=O)=O)n[n]1-c1ccccc1 ZCHGTAIGWVCOPK-UHFFFAOYSA-N 0.000 description 1
- PXVWKAMYEXONBP-UHFFFAOYSA-N CC(C)(C)c(cc1NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N3)c2NC3=O)=O)n[n]1-c1ccccc1 Chemical compound CC(C)(C)c(cc1NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N3)c2NC3=O)=O)n[n]1-c1ccccc1 PXVWKAMYEXONBP-UHFFFAOYSA-N 0.000 description 1
- BXJIDCANXSNGNH-UHFFFAOYSA-N CC(C)(C)c(cc1NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N3C)c2NC3=O)=O)n[n]1-c1ccccc1 Chemical compound CC(C)(C)c(cc1NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N3C)c2NC3=O)=O)n[n]1-c1ccccc1 BXJIDCANXSNGNH-UHFFFAOYSA-N 0.000 description 1
- OQFJAIUUSJZJCS-UHFFFAOYSA-N CC(C)(C)c(cc1NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N3c(ccc4c(cc5)Oc(ccnc6N=C7)c6NC7=O)nc4c5NC(Nc4cc(C(F)(F)F)ccc4F)=O)c2N=C(C)C3=O)=O)n[n]1-c1ccccc1 Chemical compound CC(C)(C)c(cc1NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N3c(ccc4c(cc5)Oc(ccnc6N=C7)c6NC7=O)nc4c5NC(Nc4cc(C(F)(F)F)ccc4F)=O)c2N=C(C)C3=O)=O)n[n]1-c1ccccc1 OQFJAIUUSJZJCS-UHFFFAOYSA-N 0.000 description 1
- KQAFRTUOPPOINF-UHFFFAOYSA-N CC(C)(C)c(cc1NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N=C3)c2NC3=O)=O)n[n]1-c1ccccc1 Chemical compound CC(C)(C)c(cc1NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N=C3)c2NC3=O)=O)n[n]1-c1ccccc1 KQAFRTUOPPOINF-UHFFFAOYSA-N 0.000 description 1
- RYLGLIHUAIAPRD-UHFFFAOYSA-N CC(C)(C)c(cc1NC(Nc(cc2)c3ncccc3c2Oc2ccnc(N3)c2N=CC3=O)=O)n[n]1-c1ccc(C)cc1 Chemical compound CC(C)(C)c(cc1NC(Nc(cc2)c3ncccc3c2Oc2ccnc(N3)c2N=CC3=O)=O)n[n]1-c1ccc(C)cc1 RYLGLIHUAIAPRD-UHFFFAOYSA-N 0.000 description 1
- CXXJYUVMZVPNFO-UHFFFAOYSA-N CC(C)(C)c1cc(NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N3Cc(ccc4c(cc5)Oc(ccnc6N7)c6N=C(C)C7=O)nc4c5NC(Nc4cc(C(F)(F)F)ccc4F)=O)c2NC3=O)=O)ccc1 Chemical compound CC(C)(C)c1cc(NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N3Cc(ccc4c(cc5)Oc(ccnc6N7)c6N=C(C)C7=O)nc4c5NC(Nc4cc(C(F)(F)F)ccc4F)=O)c2NC3=O)=O)ccc1 CXXJYUVMZVPNFO-UHFFFAOYSA-N 0.000 description 1
- CWLVNHSJQRAMGN-UHFFFAOYSA-N CC(C)(C)c1n[n](C)c(NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N3)c2N=C(C)C3=O)=O)c1 Chemical compound CC(C)(C)c1n[n](C)c(NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N3)c2N=C(C)C3=O)=O)c1 CWLVNHSJQRAMGN-UHFFFAOYSA-N 0.000 description 1
- GBLAGKNGZABPAI-UHFFFAOYSA-N CC(C)(C)c1n[n](C)c(NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N3C)c2NC3=O)=O)c1 Chemical compound CC(C)(C)c1n[n](C)c(NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N3C)c2NC3=O)=O)c1 GBLAGKNGZABPAI-UHFFFAOYSA-N 0.000 description 1
- GADIXAOZEUPTNN-UHFFFAOYSA-N CC(C)(C)c1n[n](CC#C)c(NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N3)c2N=C(C)C3=O)=O)c1 Chemical compound CC(C)(C)c1n[n](CC#C)c(NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N3)c2N=C(C)C3=O)=O)c1 GADIXAOZEUPTNN-UHFFFAOYSA-N 0.000 description 1
- PGGVDDPFPVRMFT-UHFFFAOYSA-N CC(C)(C)c1n[n](CC#C)c(NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N3)c2N=CC3=O)=O)c1 Chemical compound CC(C)(C)c1n[n](CC#C)c(NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N3)c2N=CC3=O)=O)c1 PGGVDDPFPVRMFT-UHFFFAOYSA-N 0.000 description 1
- MIWDWEGHFKZMPY-UHFFFAOYSA-N CC(C)(C)c1n[n](CC=C)c(NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N3)c2N=C(C)C3=O)=O)c1 Chemical compound CC(C)(C)c1n[n](CC=C)c(NC(Nc(cc2)c3ncccc3c2Oc(ccnc2N3)c2N=C(C)C3=O)=O)c1 MIWDWEGHFKZMPY-UHFFFAOYSA-N 0.000 description 1
- UMZXCENJRKMTMD-UHFFFAOYSA-N O=C(Cc1cccc(C(F)(F)F)c1)Nc(cc1)c(cccn2)c2c1Oc(ccnc1N2)c1NC2=O Chemical compound O=C(Cc1cccc(C(F)(F)F)c1)Nc(cc1)c(cccn2)c2c1Oc(ccnc1N2)c1NC2=O UMZXCENJRKMTMD-UHFFFAOYSA-N 0.000 description 1
- ZKJOHMNDIPVMQY-UHFFFAOYSA-N O=C(Cc1cccc(OC(F)(F)F)c1)Nc(cc1)c(cccn2)c2c1Oc(ccnc1N2)c1NC2=O Chemical compound O=C(Cc1cccc(OC(F)(F)F)c1)Nc(cc1)c(cccn2)c2c1Oc(ccnc1N2)c1NC2=O ZKJOHMNDIPVMQY-UHFFFAOYSA-N 0.000 description 1
- QCOMGVGQTCJQFN-UHFFFAOYSA-N O=C(Nc(cc1)c(cccn2)c2c1Oc(ccnc1N2)c1NC2=O)Nc1cc(C(F)(F)F)ccc1F Chemical compound O=C(Nc(cc1)c(cccn2)c2c1Oc(ccnc1N2)c1NC2=O)Nc1cc(C(F)(F)F)ccc1F QCOMGVGQTCJQFN-UHFFFAOYSA-N 0.000 description 1
- ZMBODPKMZWUNRC-UHFFFAOYSA-N O=C(Nc(cc1)c2ncccc2c1Oc(ccnc1N2)c1N=CC2=O)Nc1cc(C(F)(F)F)ccc1F Chemical compound O=C(Nc(cc1)c2ncccc2c1Oc(ccnc1N2)c1N=CC2=O)Nc1cc(C(F)(F)F)ccc1F ZMBODPKMZWUNRC-UHFFFAOYSA-N 0.000 description 1
- QOMBDSLLDLQYSB-UHFFFAOYSA-N O=C(Nc(cc1)c2ncccc2c1Oc(ccnc1N2)c1NC2=O)Nc(cc(C(F)(F)F)cc1)c1F Chemical compound O=C(Nc(cc1)c2ncccc2c1Oc(ccnc1N2)c1NC2=O)Nc(cc(C(F)(F)F)cc1)c1F QOMBDSLLDLQYSB-UHFFFAOYSA-N 0.000 description 1
- ZDOYCGYEVDLNMK-UHFFFAOYSA-N O=C(Nc(cc1C(F)(F)F)ccc1Cl)Nc(cc1)c(cccn2)c2c1Oc(ccnc1N2)c1NC2=O Chemical compound O=C(Nc(cc1C(F)(F)F)ccc1Cl)Nc(cc1)c(cccn2)c2c1Oc(ccnc1N2)c1NC2=O ZDOYCGYEVDLNMK-UHFFFAOYSA-N 0.000 description 1
- PLYDJXZQVQHDON-UHFFFAOYSA-N O=C(Nc(cc1C(F)(F)F)ccc1Cl)Nc(cc1)c2ncccc2c1Oc(ccnc1N2)c1NC2=O Chemical compound O=C(Nc(cc1C(F)(F)F)ccc1Cl)Nc(cc1)c2ncccc2c1Oc(ccnc1N2)c1NC2=O PLYDJXZQVQHDON-UHFFFAOYSA-N 0.000 description 1
- NITSFTLBQYEDPT-UHFFFAOYSA-N O=C(Nc1cccc(C(F)(F)F)c1)Nc(cc1)c2ncccc2c1Oc(ccnc1N2)c1NC2=O Chemical compound O=C(Nc1cccc(C(F)(F)F)c1)Nc(cc1)c2ncccc2c1Oc(ccnc1N2)c1NC2=O NITSFTLBQYEDPT-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4790208P | 2008-04-25 | 2008-04-25 | |
| US61/047,902 | 2008-04-25 | ||
| GBGB0807609.3A GB0807609D0 (en) | 2008-04-25 | 2008-04-25 | Therapeutic compounds and their use |
| GB0807609.3 | 2008-04-25 | ||
| PCT/GB2009/001077 WO2009130487A1 (en) | 2008-04-25 | 2009-04-27 | Aryl-quinolyl compounds and their use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011518819A JP2011518819A (ja) | 2011-06-30 |
| JP2011518819A5 true JP2011518819A5 (https=) | 2012-04-26 |
Family
ID=39522596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011505593A Withdrawn JP2011518819A (ja) | 2008-04-25 | 2009-04-27 | アリール−キノリル化合物及びその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8383816B2 (https=) |
| EP (1) | EP2285805B1 (https=) |
| JP (1) | JP2011518819A (https=) |
| CN (1) | CN102066371A (https=) |
| AU (1) | AU2009239785A1 (https=) |
| BR (1) | BRPI0911525A2 (https=) |
| CA (1) | CA2721575A1 (https=) |
| GB (1) | GB0807609D0 (https=) |
| WO (1) | WO2009130487A1 (https=) |
| ZA (1) | ZA201007395B (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2008337286B2 (en) | 2007-12-19 | 2014-08-07 | Cancer Research Technology Limited | Pyrido[2,3-b]pyrazine-8-substituted compounds and their use |
| ES2392482T3 (es) * | 2008-02-29 | 2012-12-11 | Array Biopharma, Inc. | Derivados de imidazo[4,5-b] piridina usados como inhibidores de RAF |
| PE20091561A1 (es) * | 2008-02-29 | 2009-10-30 | Array Biopharma Inc | Compuestos inhibidores de raf y metodos para su uso |
| JP2011513332A (ja) * | 2008-02-29 | 2011-04-28 | アレイ バイオファーマ、インコーポレイテッド | 癌の治療のためのｒａｆ阻害剤としてのｎ−（６−アミノピリジン−３−イル）−３−（スルホンアミド）ベンズアミド誘導体 |
| JP2011513331A (ja) * | 2008-02-29 | 2011-04-28 | アレイ バイオファーマ、インコーポレイテッド | ピラゾール［３，４−ｂ］ピリジンＲＡＦ阻害剤 |
| GB0807609D0 (en) | 2008-04-25 | 2008-06-04 | Cancer Rec Tech Ltd | Therapeutic compounds and their use |
| NZ601085A (en) | 2010-02-01 | 2015-04-24 | Cancer Rec Tech Ltd | 1-(5-tert-butyl-2-phenyl-2h-pyrazol-3-yl)-3-[2-fluoro-4-(1-methyl-2-oxo-2,3-dihydro-1h-imidazo[4,5-b]pyridin-7-yloxy)-phenyl]-urea and related compounds and their use in therapy |
| US8933228B2 (en) | 2010-06-17 | 2015-01-13 | Respivert, Ltd. | Respiratory formulations and compounds for use therein |
| MX2013010163A (es) * | 2011-03-09 | 2013-10-30 | Merck Patent Gmbh | Derivados de pirido[2,3-b] pirazina y sus usos terapeuticos. |
| US9670203B2 (en) * | 2013-06-28 | 2017-06-06 | Beigene, Ltd. | Fused tricyclic urea compounds as Raf kinase and/or Raf kinase dimer inhibitors |
| GB201320729D0 (en) | 2013-11-25 | 2014-01-08 | Cancer Rec Tech Ltd | Therapeutic compounds and their use |
| GB201320732D0 (en) | 2013-11-25 | 2014-01-08 | Cancer Rec Tech Ltd | Methods of chemical synthesis |
| EP3575305A1 (fr) | 2018-05-31 | 2019-12-04 | Biocidal Alternative Solutions | Procédé de fabrication de composés comprenant un groupe fonctionnel oxazolopyridinones |
| JOP20180131B1 (ar) * | 2018-12-24 | 2023-03-28 | Univ Of Petra | مركبات الكوينولون المستبدلة واستخدامها في علاج السرطان وطريقة تحضيرها |
| TWI812301B (zh) * | 2021-06-24 | 2023-08-11 | 南韓商Ｌｇ化學股份有限公司 | 作為ｒｏｎ抑制劑之新穎尿素衍生物化合物 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US238568A (en) * | 1881-03-08 | Washing-machine | ||
| JPS5665863A (en) | 1979-10-31 | 1981-06-03 | Tokyo Organ Chem Ind Ltd | Novel aniline derivative, its preparation and pesticide containing the same |
| JPS5738777A (en) | 1980-08-19 | 1982-03-03 | Sogo Yatsukou Kk | 2-sufanilamidopyrathyn derivative |
| US4666828A (en) * | 1984-08-15 | 1987-05-19 | The General Hospital Corporation | Test for Huntington's disease |
| US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4801531A (en) * | 1985-04-17 | 1989-01-31 | Biotechnology Research Partners, Ltd. | Apo AI/CIII genomic polymorphisms predictive of atherosclerosis |
| US5272057A (en) * | 1988-10-14 | 1993-12-21 | Georgetown University | Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase |
| US5192659A (en) * | 1989-08-25 | 1993-03-09 | Genetype Ag | Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes |
| US5879672A (en) * | 1994-10-07 | 1999-03-09 | Regeneron Pharmaceuticals, Inc. | Tie-2 ligand 1 |
| US5643755A (en) * | 1994-10-07 | 1997-07-01 | Regeneron Pharmaceuticals Inc. | Nucleic acid encoding tie-2 ligand |
| DE69534180T2 (de) * | 1994-09-22 | 2006-03-02 | Licentia Ltd. | Promotor der tie rezeptor protein kinase |
| US6218529B1 (en) * | 1995-07-31 | 2001-04-17 | Urocor, Inc. | Biomarkers and targets for diagnosis, prognosis and management of prostate, breast and bladder cancer |
| WO1998004689A1 (en) * | 1995-07-31 | 1998-02-05 | Urocor, Inc. | Biomarkers and targets for diagnosis, prognosis and management of prostate disease |
| ZA971896B (en) * | 1996-03-26 | 1998-09-07 | Du Pont Merck Pharma | Aryloxy-and arythio-fused pyridines and pyrimidines and derivatives |
| KR100567649B1 (ko) | 1996-09-25 | 2006-04-05 | 아스트라제네카 유케이 리미티드 | 혈관 내피 성장 인자와 같은 성장 인자의 효과를 억제하는 퀴놀린 유도체 |
| US6030831A (en) * | 1997-09-19 | 2000-02-29 | Genetech, Inc. | Tie ligand homologues |
| NZ503432A (en) | 1997-09-26 | 2002-11-26 | Zentaris Gmbh | Azabenzimidazole-based compounds for modulating serine/threonine protein kinase function |
| GB9721437D0 (en) | 1997-10-10 | 1997-12-10 | Glaxo Group Ltd | Heteroaromatic compounds and their use in medicine |
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| WO2001046196A1 (en) | 1999-12-21 | 2001-06-28 | Sugen, Inc. | 4-substituted 7-aza-indolin-2-ones and their use as protein kinase inhibitors |
| US6492529B1 (en) * | 2000-01-18 | 2002-12-10 | Boehringer Ingelheim Pharmaceuticals, Inc. | Bis pyrazole-1H-pyrazole intermediates and their synthesis |
| AU2002232439A1 (en) * | 2000-11-29 | 2002-06-11 | Glaxo Group Limited | Benzimidazole derivatives useful as tie-2 and/or vegfr-2 inhibitors |
| NZ532780A (en) | 2001-12-21 | 2006-10-27 | Wellcome Trust | Isolated naturally occurring mutant human B-Raf polypeptides and nucleic acids encoding them |
| US20060128783A1 (en) | 2002-08-09 | 2006-06-15 | Dinsmore Christopher J | Tyrosine kinase inhibitors |
| WO2005080377A1 (ja) | 2004-02-20 | 2005-09-01 | Kirin Beer Kabushiki Kaisha | TGFβ阻害活性を有する化合物およびそれを含んでなる医薬組成物 |
| TW200616974A (en) | 2004-07-01 | 2006-06-01 | Astrazeneca Ab | Chemical compounds |
| BRPI0514691A (pt) | 2004-08-31 | 2008-06-17 | Astrazeneca Ab | composto ou um sal farmaceuticamente aceitável do mesmo, processo para preparar o mesmo, composição farmacêutica, e, uso de um composto ou um sal farmaceuticamente aceitável do mesmo |
| GB0423554D0 (en) * | 2004-10-22 | 2004-11-24 | Cancer Rec Tech Ltd | Therapeutic compounds |
| GB0428082D0 (en) | 2004-12-22 | 2005-01-26 | Welcome Trust The Ltd | Therapeutic compounds |
| CN101365682A (zh) | 2005-12-08 | 2009-02-11 | 千禧药品公司 | 具有激酶抑制活性的双环化合物 |
| US7989461B2 (en) | 2005-12-23 | 2011-08-02 | Amgen Inc. | Substituted quinazolinamine compounds for the treatment of cancer |
| AU2007245495A1 (en) * | 2006-04-26 | 2007-11-08 | Astex Therapeutics Limited | Imidazo[4, 5-b]pyridin-2-one and oxazolo[4, 5-b]pyridin-2-one compounds and analogs thereof as cancer therapeutic compounds |
| WO2008044688A1 (en) * | 2006-10-11 | 2008-04-17 | Daiichi Sankyo Company, Limited | Urea derivative |
| AU2008337286B2 (en) | 2007-12-19 | 2014-08-07 | Cancer Research Technology Limited | Pyrido[2,3-b]pyrazine-8-substituted compounds and their use |
| GB0807609D0 (en) | 2008-04-25 | 2008-06-04 | Cancer Rec Tech Ltd | Therapeutic compounds and their use |
| NZ601085A (en) | 2010-02-01 | 2015-04-24 | Cancer Rec Tech Ltd | 1-(5-tert-butyl-2-phenyl-2h-pyrazol-3-yl)-3-[2-fluoro-4-(1-methyl-2-oxo-2,3-dihydro-1h-imidazo[4,5-b]pyridin-7-yloxy)-phenyl]-urea and related compounds and their use in therapy |
-
2008
- 2008-04-25 GB GBGB0807609.3A patent/GB0807609D0/en not_active Ceased
-
2009
- 2009-04-27 AU AU2009239785A patent/AU2009239785A1/en not_active Abandoned
- 2009-04-27 JP JP2011505593A patent/JP2011518819A/ja not_active Withdrawn
- 2009-04-27 CA CA2721575A patent/CA2721575A1/en not_active Abandoned
- 2009-04-27 CN CN2009801234973A patent/CN102066371A/zh active Pending
- 2009-04-27 WO PCT/GB2009/001077 patent/WO2009130487A1/en not_active Ceased
- 2009-04-27 BR BRPI0911525-0A patent/BRPI0911525A2/pt not_active IP Right Cessation
- 2009-04-27 US US12/988,619 patent/US8383816B2/en not_active Expired - Fee Related
- 2009-04-27 EP EP09734443.6A patent/EP2285805B1/en active Active
-
2010
- 2010-10-15 ZA ZA2010/07395A patent/ZA201007395B/en unknown
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