JP2011518811A5 - - Google Patents
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- Publication number
- JP2011518811A5 JP2011518811A5 JP2011505534A JP2011505534A JP2011518811A5 JP 2011518811 A5 JP2011518811 A5 JP 2011518811A5 JP 2011505534 A JP2011505534 A JP 2011505534A JP 2011505534 A JP2011505534 A JP 2011505534A JP 2011518811 A5 JP2011518811 A5 JP 2011518811A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- pyrazol
- methyl
- yloxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 Cc1cc(OCCN(*)*)n[n]1-c1ccc([C@@](C2)C2C=C2)c2c1 Chemical compound Cc1cc(OCCN(*)*)n[n]1-c1ccc([C@@](C2)C2C=C2)c2c1 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08384005A EP2113501A1 (en) | 2008-04-25 | 2008-04-25 | 5-Methyl-1-(naphthalen-2-YL)-1H-Pyrazoles useful as sigma receptor inhibitors |
| EP08384005.8 | 2008-04-25 | ||
| PCT/EP2009/055065 WO2009130331A1 (en) | 2008-04-25 | 2009-04-27 | 5-methyl-1-(naphthalen-2-yl)-1h-pyrazoles useful as sigma receptor inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011518811A JP2011518811A (ja) | 2011-06-30 |
| JP2011518811A5 true JP2011518811A5 (enExample) | 2012-06-07 |
Family
ID=39739580
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011505534A Pending JP2011518811A (ja) | 2008-04-25 | 2009-04-27 | シグマ受容体阻害剤として有用な５−メチル−１−（ナフタレン−２−イル）−１ｈ−ピラゾール |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8492425B2 (enExample) |
| EP (2) | EP2113501A1 (enExample) |
| JP (1) | JP2011518811A (enExample) |
| KR (1) | KR20110006697A (enExample) |
| CN (1) | CN102066333A (enExample) |
| AU (1) | AU2009239906A1 (enExample) |
| BR (1) | BRPI0910679A2 (enExample) |
| CA (1) | CA2722256A1 (enExample) |
| MX (1) | MX2010011674A (enExample) |
| RU (1) | RU2010147918A (enExample) |
| WO (1) | WO2009130331A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2116539A1 (en) | 2008-04-25 | 2009-11-11 | Laboratorios Del. Dr. Esteve, S.A. | 1-aryl-3-aminoalkoxy-pyrazoles as sigma ligands enhancing analgesic effects of opioids and attenuating the dependency thereof |
| EP2361904A1 (en) * | 2010-02-04 | 2011-08-31 | Laboratorios Del. Dr. Esteve, S.A. | 4-[-2-[[5-methyl-1-(2-naphtalenyl)-1h-pyrazol-3-yl]oxy]ethyl]morpholine hydrochloride and crystalline forms thereof |
| US20130143884A1 (en) * | 2009-11-25 | 2013-06-06 | Maria Rosa Cuberes-Altisent | 4-[2-[ [5-methyl-1-(2-naphtalenyl)-1h-pyrazol-3-yl]oxy]ethyl] morpholine salts |
| EP2353591A1 (en) | 2010-02-04 | 2011-08-10 | Laboratorios Del. Dr. Esteve, S.A. | Sigma ligands for potentiating the analgesic effect of opioids and opiates in post-operative pain and attenuating the dependency thereof |
| RS55046B1 (sr) * | 2010-02-04 | 2016-12-30 | Esteve Labor Dr | 4-[2-[[5-metil-1-(2-naftalenil)-1h-pirazol-3-il]oksi]etil]morfolin hidrohlorid i solvati |
| EP2353598A1 (en) | 2010-02-04 | 2011-08-10 | Laboratorios Del. Dr. Esteve, S.A. | Sigma ligands for use in the prevention and/or treatment of postoperative pain |
| EP2388005A1 (en) | 2010-05-21 | 2011-11-23 | Laboratorios Del. Dr. Esteve, S.A. | Sigma ligands for the prevention and/or treatment of emesis induced by chemotherapy or radiotherapy |
| EP2395003A1 (en) | 2010-05-27 | 2011-12-14 | Laboratorios Del. Dr. Esteve, S.A. | Pyrazole compounds as sigma receptor inhibitors |
| EP2418192A1 (en) * | 2010-07-30 | 2012-02-15 | Esteve Química, S.A. | Intermediates for the preparation of 1-aryl-pyrazol-3-one compounds useful as sigma receptors inhibitors |
| EP2415471A1 (en) | 2010-08-03 | 2012-02-08 | Laboratorios Del. Dr. Esteve, S.A. | Use of sigma ligands in opioid-induced hyperalgesia |
| EP2426111A1 (en) * | 2010-08-09 | 2012-03-07 | Laboratorios Del. Dr. Esteve, S.A. | 4-[-2-[[5-methyl-1-(2-naphtalenyl)-1h-pyrazol-3-yl]oxy]ethyl]morpholine hydrochloride amorphous solid forms |
| EP2460519A1 (en) | 2010-12-03 | 2012-06-06 | Laboratorios Del. Dr. Esteve, S.A. | Use of sigma ligands in bone cancer pain |
| EP2460804A1 (en) * | 2010-12-03 | 2012-06-06 | Laboratorios Del Dr. Esteve, S.A. | 5-methyl-1-(naphthalen-2-yl)-1h-pyrazole derivatives and their use in potentiating the effect of opioid analgesics |
| EP2524694A1 (en) | 2011-05-19 | 2012-11-21 | Laboratorios Del. Dr. Esteve, S.A. | Use of sigma ligands in diabetes type-2 associated pain |
| EP2818166A1 (en) * | 2013-06-26 | 2014-12-31 | Laboratorios del Dr. Esteve S.A. | Use of sigma receptor ligands for the prevention and treatment of pain associated to interstitial cystitis/bladder pain syndrome (IC/BPS) |
| AU2014364647A1 (en) | 2013-12-17 | 2016-06-23 | Laboratorios Del Dr. Esteve, S.A. | Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs) and Sigma receptor ligands combinations |
| WO2016019288A1 (en) | 2014-08-01 | 2016-02-04 | Smart Billiard Lighting LLC | Billiard table lighting and game play monitor |
| MA41177A (fr) * | 2014-12-15 | 2017-10-24 | Esteve Labor Dr | Utilisation de ligands des récepteurs sigma dans l'arthrose |
| US12345406B2 (en) | 2022-02-09 | 2025-07-01 | Blake Martin | Interactive LED system for enhancing billiard gameplay |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9824310D0 (en) | 1998-11-05 | 1998-12-30 | Univ London | Activators of soluble guanylate cyclase |
| EP2325174A1 (en) | 2004-08-27 | 2011-05-25 | Laboratorios Del. Dr. Esteve, S.A. | Sigma receptor inhibitors |
| EP1634872A1 (en) * | 2004-08-27 | 2006-03-15 | Laboratorios Del Dr. Esteve, S.A. | Pyrazole derivatives as sigma receptor inhibitors |
| EP1829875A1 (en) * | 2006-03-01 | 2007-09-05 | Laboratorios Del Dr. Esteve, S.A. | Pyrazole derivatives as sigma receptor inhibitors |
| US8202872B2 (en) | 2006-03-01 | 2012-06-19 | Laboratorios Del Dr. Esteve, S.A. | Pyrazole derivatives as sigma receptor inhibitors |
-
2008
- 2008-04-25 EP EP08384005A patent/EP2113501A1/en not_active Withdrawn
-
2009
- 2009-04-27 MX MX2010011674A patent/MX2010011674A/es unknown
- 2009-04-27 AU AU2009239906A patent/AU2009239906A1/en not_active Abandoned
- 2009-04-27 EP EP09734847A patent/EP2285781A1/en not_active Withdrawn
- 2009-04-27 US US12/988,929 patent/US8492425B2/en not_active Expired - Fee Related
- 2009-04-27 RU RU2010147918/04A patent/RU2010147918A/ru not_active Application Discontinuation
- 2009-04-27 CA CA2722256A patent/CA2722256A1/en not_active Abandoned
- 2009-04-27 KR KR1020107026489A patent/KR20110006697A/ko not_active Withdrawn
- 2009-04-27 JP JP2011505534A patent/JP2011518811A/ja active Pending
- 2009-04-27 CN CN200980122589XA patent/CN102066333A/zh active Pending
- 2009-04-27 BR BRPI0910679A patent/BRPI0910679A2/pt not_active IP Right Cessation
- 2009-04-27 WO PCT/EP2009/055065 patent/WO2009130331A1/en not_active Ceased
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