JP2011518566A5 - - Google Patents
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- Publication number
- JP2011518566A5 JP2011518566A5 JP2011506500A JP2011506500A JP2011518566A5 JP 2011518566 A5 JP2011518566 A5 JP 2011518566A5 JP 2011506500 A JP2011506500 A JP 2011506500A JP 2011506500 A JP2011506500 A JP 2011506500A JP 2011518566 A5 JP2011518566 A5 JP 2011518566A5
- Authority
- JP
- Japan
- Prior art keywords
- mouse
- abi
- gene
- prostate
- knockout
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 241000699666 Mus <mouse, genus> Species 0.000 claims 12
- 108050004693 Abl interactor 1 Proteins 0.000 claims 10
- 238000011813 knockout mouse model Methods 0.000 claims 7
- 210000002307 prostate Anatomy 0.000 claims 7
- 210000004027 cell Anatomy 0.000 claims 6
- 239000003550 marker Substances 0.000 claims 6
- 241000699670 Mus sp. Species 0.000 claims 4
- 102100028247 Abl interactor 1 Human genes 0.000 claims 3
- 108700028369 Alleles Proteins 0.000 claims 2
- 108010051219 Cre recombinase Proteins 0.000 claims 2
- 101100107635 Mus musculus Abi1 gene Proteins 0.000 claims 2
- 230000003247 decreasing effect Effects 0.000 claims 2
- 210000001161 mammalian embryo Anatomy 0.000 claims 2
- 230000005012 migration Effects 0.000 claims 2
- 238000013508 migration Methods 0.000 claims 2
- 208000021046 prostate intraepithelial neoplasia Diseases 0.000 claims 2
- 101001010097 Shigella phage SfV Bactoprenol-linked glucose translocase Proteins 0.000 claims 1
- 230000001093 anti-cancer Effects 0.000 claims 1
- 230000009087 cell motility Effects 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 238000003209 gene knockout Methods 0.000 claims 1
- 210000004602 germ cell Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000002688 persistence Effects 0.000 claims 1
- 210000005267 prostate cell Anatomy 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
- 108700026220 vif Genes Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4813008P | 2008-04-25 | 2008-04-25 | |
| US61/048,130 | 2008-04-25 | ||
| PCT/US2009/041846 WO2009132357A1 (en) | 2008-04-25 | 2009-04-27 | Abi1/hssh3bp1 conditional knockout mouse |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011518566A JP2011518566A (ja) | 2011-06-30 |
| JP2011518566A5 true JP2011518566A5 (enExample) | 2012-04-19 |
Family
ID=40823240
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011506500A Pending JP2011518566A (ja) | 2008-04-25 | 2009-04-27 | Ａｂｉ１／ｈｓｓｈ３ｂｐ１コンディショナルノックアウトマウス |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8110719B2 (enExample) |
| EP (1) | EP2268821A1 (enExample) |
| JP (1) | JP2011518566A (enExample) |
| AU (1) | AU2009240404A1 (enExample) |
| CA (1) | CA2719267A1 (enExample) |
| IL (1) | IL208904A0 (enExample) |
| WO (1) | WO2009132357A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5867671B2 (ja) * | 2011-03-28 | 2016-02-24 | 国立大学法人神戸大学 | コンディショナルノックアウト動物 |
| EP2918166A1 (en) | 2014-03-10 | 2015-09-16 | Westfälische Wilhelms-Universität Münster | TTP/MRP14 double knock out mouse model of psoriasis |
| CA3155265A1 (en) * | 2019-11-04 | 2021-05-14 | Regeneron Pharmaceuticals, Inc. | A rodent model of increased bone mineral density |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1092768A1 (en) * | 1999-10-16 | 2001-04-18 | ARTEMIS Pharmaceuticals GmbH | Conditional gene trapping construct for the disruption of genes |
| CA2396149A1 (en) * | 2000-01-07 | 2001-07-12 | Artemis Pharmaceuticals Gmbh | Transduction of recombinases for inducible gene targeting |
| AU2002224022A1 (en) * | 2000-11-10 | 2002-05-21 | Kissei Pharmaceutical Co. Ltd. | Preventives or remedies for endoplasmic reticulum stress-associated diseases |
| JP4690630B2 (ja) * | 2002-05-02 | 2011-06-01 | 独立行政法人科学技術振興機構 | Ｍｄ−２遺伝子改変モデル非ヒト動物 |
| JPWO2004014131A1 (ja) * | 2002-08-09 | 2005-11-24 | 株式会社Ｌｓｓ | ノックイン非ヒト動物及び組織特異的ＭｎＳＯＤノックアウト非ヒト動物 |
| BRPI0409528A (pt) * | 2003-03-28 | 2006-05-02 | Neo Morgan Lab Inc | método para intervir rapidamente, em uma desejada peculiaridade de um organismo, uma célula, um organismo, uma molécula de ácido nucléico, um polipeptìdeo, um metabólito, um vetor, uma substáncia de produto, método para testar um medicamento, um conjunto de ao menos dois tipos de polmerásicos e uso dos mesmos |
| US7205148B2 (en) * | 2003-06-11 | 2007-04-17 | Regeneron Pharmaceuticals, Inc. | Genome mutation by intron insertion into an embryonic stem cell genome |
| WO2005084429A1 (ja) * | 2004-03-04 | 2005-09-15 | Cellseed Inc. | 癌細胞移植動物の製造方法 |
| WO2006004066A1 (ja) * | 2004-07-02 | 2006-01-12 | Locomogene, Inc. | S1-5を含有するタンパク質製剤 |
| JP4550530B2 (ja) * | 2004-09-03 | 2010-09-22 | 独立行政法人科学技術振興機構 | シナプス成熟障害モデル動物 |
| AU2006287315B2 (en) * | 2005-09-09 | 2013-02-21 | The Johns Hopkins University | Manipulation of regulatory T cell and DC function by targeting neuritin gene using antibodies, agonists and antagonists |
| AU2007262083B2 (en) * | 2006-06-20 | 2012-01-19 | Toray Industries, Inc. | Therapeutic or prophylactic agent for leukemia |
-
2009
- 2009-04-27 US US12/430,814 patent/US8110719B2/en not_active Expired - Fee Related
- 2009-04-27 EP EP09734240A patent/EP2268821A1/en not_active Ceased
- 2009-04-27 CA CA2719267A patent/CA2719267A1/en not_active Abandoned
- 2009-04-27 AU AU2009240404A patent/AU2009240404A1/en not_active Abandoned
- 2009-04-27 JP JP2011506500A patent/JP2011518566A/ja active Pending
- 2009-04-27 WO PCT/US2009/041846 patent/WO2009132357A1/en not_active Ceased
-
2010
- 2010-10-24 IL IL208904A patent/IL208904A0/en unknown
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