IL208904A0 - Abi1/hssh3bp1 conditional knockut mouse - Google Patents

Abi1/hssh3bp1 conditional knockut mouse

Info

Publication number
IL208904A0
IL208904A0 IL208904A IL20890410A IL208904A0 IL 208904 A0 IL208904 A0 IL 208904A0 IL 208904 A IL208904 A IL 208904A IL 20890410 A IL20890410 A IL 20890410A IL 208904 A0 IL208904 A0 IL 208904A0
Authority
IL
Israel
Prior art keywords
knockut
hssh3bp1
abi1
conditional
mouse
Prior art date
Application number
IL208904A
Other languages
English (en)
Original Assignee
New York Blood Ct Inc
Leszek Kotula
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York Blood Ct Inc, Leszek Kotula filed Critical New York Blood Ct Inc
Publication of IL208904A0 publication Critical patent/IL208904A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0331—Animal model for proliferative diseases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL208904A 2008-04-25 2010-10-24 Abi1/hssh3bp1 conditional knockut mouse IL208904A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4813008P 2008-04-25 2008-04-25
PCT/US2009/041846 WO2009132357A1 (en) 2008-04-25 2009-04-27 Abi1/hssh3bp1 conditional knockout mouse

Publications (1)

Publication Number Publication Date
IL208904A0 true IL208904A0 (en) 2011-01-31

Family

ID=40823240

Family Applications (1)

Application Number Title Priority Date Filing Date
IL208904A IL208904A0 (en) 2008-04-25 2010-10-24 Abi1/hssh3bp1 conditional knockut mouse

Country Status (7)

Country Link
US (1) US8110719B2 (enExample)
EP (1) EP2268821A1 (enExample)
JP (1) JP2011518566A (enExample)
AU (1) AU2009240404A1 (enExample)
CA (1) CA2719267A1 (enExample)
IL (1) IL208904A0 (enExample)
WO (1) WO2009132357A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5867671B2 (ja) * 2011-03-28 2016-02-24 国立大学法人神戸大学 コンディショナルノックアウト動物
EP2918166A1 (en) 2014-03-10 2015-09-16 Westfälische Wilhelms-Universität Münster TTP/MRP14 double knock out mouse model of psoriasis
CA3155265A1 (en) * 2019-11-04 2021-05-14 Regeneron Pharmaceuticals, Inc. A rodent model of increased bone mineral density

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1092768A1 (en) * 1999-10-16 2001-04-18 ARTEMIS Pharmaceuticals GmbH Conditional gene trapping construct for the disruption of genes
CA2396149A1 (en) * 2000-01-07 2001-07-12 Artemis Pharmaceuticals Gmbh Transduction of recombinases for inducible gene targeting
AU2002224022A1 (en) * 2000-11-10 2002-05-21 Kissei Pharmaceutical Co. Ltd. Preventives or remedies for endoplasmic reticulum stress-associated diseases
JP4690630B2 (ja) * 2002-05-02 2011-06-01 独立行政法人科学技術振興機構 Ｍｄ−２遺伝子改変モデル非ヒト動物
JPWO2004014131A1 (ja) * 2002-08-09 2005-11-24 株式会社Ｌｓｓ ノックイン非ヒト動物及び組織特異的ＭｎＳＯＤノックアウト非ヒト動物
BRPI0409528A (pt) * 2003-03-28 2006-05-02 Neo Morgan Lab Inc método para intervir rapidamente, em uma desejada peculiaridade de um organismo, uma célula, um organismo, uma molécula de ácido nucléico, um polipeptìdeo, um metabólito, um vetor, uma substáncia de produto, método para testar um medicamento, um conjunto de ao menos dois tipos de polmerásicos e uso dos mesmos
US7205148B2 (en) * 2003-06-11 2007-04-17 Regeneron Pharmaceuticals, Inc. Genome mutation by intron insertion into an embryonic stem cell genome
WO2005084429A1 (ja) * 2004-03-04 2005-09-15 Cellseed Inc. 癌細胞移植動物の製造方法
WO2006004066A1 (ja) * 2004-07-02 2006-01-12 Locomogene, Inc. S1-5を含有するタンパク質製剤
JP4550530B2 (ja) * 2004-09-03 2010-09-22 独立行政法人科学技術振興機構 シナプス成熟障害モデル動物
AU2006287315B2 (en) * 2005-09-09 2013-02-21 The Johns Hopkins University Manipulation of regulatory T cell and DC function by targeting neuritin gene using antibodies, agonists and antagonists
AU2007262083B2 (en) * 2006-06-20 2012-01-19 Toray Industries, Inc. Therapeutic or prophylactic agent for leukemia

Also Published As

Publication number Publication date
WO2009132357A1 (en) 2009-10-29
JP2011518566A (ja) 2011-06-30
US8110719B2 (en) 2012-02-07
US20090271883A1 (en) 2009-10-29
CA2719267A1 (en) 2009-10-29
AU2009240404A1 (en) 2009-10-29
EP2268821A1 (en) 2011-01-05
AU2009240404A2 (en) 2010-12-02

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