AU2009240404A1 - Abi1/Hssh3bp1 conditional knockout mouse - Google Patents

Abi1/Hssh3bp1 conditional knockout mouse Download PDF

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Publication number
AU2009240404A1
AU2009240404A1 AU2009240404A AU2009240404A AU2009240404A1 AU 2009240404 A1 AU2009240404 A1 AU 2009240404A1 AU 2009240404 A AU2009240404 A AU 2009240404A AU 2009240404 A AU2009240404 A AU 2009240404A AU 2009240404 A1 AU2009240404 A1 AU 2009240404A1
Authority
AU
Australia
Prior art keywords
hssh3bpl
abil
mouse
gene
conditional
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2009240404A
Other languages
English (en)
Other versions
AU2009240404A2 (en
Inventor
Leszek Kotula
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
New York Blood Center Inc
Original Assignee
New York Blood Center Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York Blood Center Inc filed Critical New York Blood Center Inc
Publication of AU2009240404A1 publication Critical patent/AU2009240404A1/en
Publication of AU2009240404A2 publication Critical patent/AU2009240404A2/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0331—Animal model for proliferative diseases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2009240404A 2008-04-25 2009-04-27 Abi1/Hssh3bp1 conditional knockout mouse Abandoned AU2009240404A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4813008P 2008-04-25 2008-04-25
US61/048,130 2008-04-25
PCT/US2009/041846 WO2009132357A1 (en) 2008-04-25 2009-04-27 Abi1/hssh3bp1 conditional knockout mouse

Publications (2)

Publication Number Publication Date
AU2009240404A1 true AU2009240404A1 (en) 2009-10-29
AU2009240404A2 AU2009240404A2 (en) 2010-12-02

Family

ID=40823240

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009240404A Abandoned AU2009240404A1 (en) 2008-04-25 2009-04-27 Abi1/Hssh3bp1 conditional knockout mouse

Country Status (7)

Country Link
US (1) US8110719B2 (enExample)
EP (1) EP2268821A1 (enExample)
JP (1) JP2011518566A (enExample)
AU (1) AU2009240404A1 (enExample)
CA (1) CA2719267A1 (enExample)
IL (1) IL208904A0 (enExample)
WO (1) WO2009132357A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5867671B2 (ja) * 2011-03-28 2016-02-24 国立大学法人神戸大学 コンディショナルノックアウト動物
EP2918166A1 (en) 2014-03-10 2015-09-16 Westfälische Wilhelms-Universität Münster TTP/MRP14 double knock out mouse model of psoriasis
CA3155265A1 (en) * 2019-11-04 2021-05-14 Regeneron Pharmaceuticals, Inc. A rodent model of increased bone mineral density

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1092768A1 (en) * 1999-10-16 2001-04-18 ARTEMIS Pharmaceuticals GmbH Conditional gene trapping construct for the disruption of genes
CA2396149A1 (en) * 2000-01-07 2001-07-12 Artemis Pharmaceuticals Gmbh Transduction of recombinases for inducible gene targeting
AU2002224022A1 (en) * 2000-11-10 2002-05-21 Kissei Pharmaceutical Co. Ltd. Preventives or remedies for endoplasmic reticulum stress-associated diseases
JP4690630B2 (ja) * 2002-05-02 2011-06-01 独立行政法人科学技術振興機構 Ｍｄ−２遺伝子改変モデル非ヒト動物
JPWO2004014131A1 (ja) * 2002-08-09 2005-11-24 株式会社Ｌｓｓ ノックイン非ヒト動物及び組織特異的ＭｎＳＯＤノックアウト非ヒト動物
BRPI0409528A (pt) * 2003-03-28 2006-05-02 Neo Morgan Lab Inc método para intervir rapidamente, em uma desejada peculiaridade de um organismo, uma célula, um organismo, uma molécula de ácido nucléico, um polipeptìdeo, um metabólito, um vetor, uma substáncia de produto, método para testar um medicamento, um conjunto de ao menos dois tipos de polmerásicos e uso dos mesmos
US7205148B2 (en) * 2003-06-11 2007-04-17 Regeneron Pharmaceuticals, Inc. Genome mutation by intron insertion into an embryonic stem cell genome
WO2005084429A1 (ja) * 2004-03-04 2005-09-15 Cellseed Inc. 癌細胞移植動物の製造方法
WO2006004066A1 (ja) * 2004-07-02 2006-01-12 Locomogene, Inc. S1-5を含有するタンパク質製剤
JP4550530B2 (ja) * 2004-09-03 2010-09-22 独立行政法人科学技術振興機構 シナプス成熟障害モデル動物
AU2006287315B2 (en) * 2005-09-09 2013-02-21 The Johns Hopkins University Manipulation of regulatory T cell and DC function by targeting neuritin gene using antibodies, agonists and antagonists
AU2007262083B2 (en) * 2006-06-20 2012-01-19 Toray Industries, Inc. Therapeutic or prophylactic agent for leukemia

Also Published As

Publication number Publication date
WO2009132357A1 (en) 2009-10-29
JP2011518566A (ja) 2011-06-30
US8110719B2 (en) 2012-02-07
US20090271883A1 (en) 2009-10-29
CA2719267A1 (en) 2009-10-29
IL208904A0 (en) 2011-01-31
EP2268821A1 (en) 2011-01-05
AU2009240404A2 (en) 2010-12-02

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Legal Events

Date Code Title Description
DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 01 SEP 2010

NA Applications received for extensions of time, section 223

Free format text: AN APPLICATION TO EXTEND THE TIME FROM 28 OCT 2009 TO 28 NOV 2010 IN WHICH TO COMPLY WITH SECTION 6(C) HAS BEEN FILED .

NB Applications allowed - extensions of time section 223(2)

Free format text: THE TIME IN WHICH TO COMPLY WITH SECTION 6(C) HAS BEEN EXTENDED TO 28 NOV 2010.

MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application