CA2719267A1 - Abi1/hssh3bp1 conditional knockout mouse - Google Patents
Abi1/hssh3bp1 conditional knockout mouse Download PDFInfo
- Publication number
- CA2719267A1 CA2719267A1 CA2719267A CA2719267A CA2719267A1 CA 2719267 A1 CA2719267 A1 CA 2719267A1 CA 2719267 A CA2719267 A CA 2719267A CA 2719267 A CA2719267 A CA 2719267A CA 2719267 A1 CA2719267 A1 CA 2719267A1
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- mouse
- hssh3bpl
- gene
- abil
- abi1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0331—Animal model for proliferative diseases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT
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- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
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- Biotechnology (AREA)
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- Chemical & Material Sciences (AREA)
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- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
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- Molecular Biology (AREA)
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- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US4813008P | 2008-04-25 | 2008-04-25 | |
| US61/048,130 | 2008-04-25 | ||
| PCT/US2009/041846 WO2009132357A1 (en) | 2008-04-25 | 2009-04-27 | Abi1/hssh3bp1 conditional knockout mouse |
Publications (1)
| Publication Number | Publication Date |
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| CA2719267A1 true CA2719267A1 (en) | 2009-10-29 |
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| CA2719267A Abandoned CA2719267A1 (en) | 2008-04-25 | 2009-04-27 | Abi1/hssh3bp1 conditional knockout mouse |
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| EP (1) | EP2268821A1 (enExample) |
| JP (1) | JP2011518566A (enExample) |
| AU (1) | AU2009240404A1 (enExample) |
| CA (1) | CA2719267A1 (enExample) |
| IL (1) | IL208904A0 (enExample) |
| WO (1) | WO2009132357A1 (enExample) |
Families Citing this family (3)
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| JP5867671B2 (ja) * | 2011-03-28 | 2016-02-24 | 国立大学法人神戸大学 | コンディショナルノックアウト動物 |
| EP2918166A1 (en) | 2014-03-10 | 2015-09-16 | Westfälische Wilhelms-Universität Münster | TTP/MRP14 double knock out mouse model of psoriasis |
| CA3155265A1 (en) * | 2019-11-04 | 2021-05-14 | Regeneron Pharmaceuticals, Inc. | A rodent model of increased bone mineral density |
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| EP1092768A1 (en) * | 1999-10-16 | 2001-04-18 | ARTEMIS Pharmaceuticals GmbH | Conditional gene trapping construct for the disruption of genes |
| CA2396149A1 (en) * | 2000-01-07 | 2001-07-12 | Artemis Pharmaceuticals Gmbh | Transduction of recombinases for inducible gene targeting |
| AU2002224022A1 (en) * | 2000-11-10 | 2002-05-21 | Kissei Pharmaceutical Co. Ltd. | Preventives or remedies for endoplasmic reticulum stress-associated diseases |
| JP4690630B2 (ja) * | 2002-05-02 | 2011-06-01 | 独立行政法人科学技術振興機構 | Ｍｄ−２遺伝子改変モデル非ヒト動物 |
| JPWO2004014131A1 (ja) * | 2002-08-09 | 2005-11-24 | 株式会社Ｌｓｓ | ノックイン非ヒト動物及び組織特異的ＭｎＳＯＤノックアウト非ヒト動物 |
| BRPI0409528A (pt) * | 2003-03-28 | 2006-05-02 | Neo Morgan Lab Inc | método para intervir rapidamente, em uma desejada peculiaridade de um organismo, uma célula, um organismo, uma molécula de ácido nucléico, um polipeptìdeo, um metabólito, um vetor, uma substáncia de produto, método para testar um medicamento, um conjunto de ao menos dois tipos de polmerásicos e uso dos mesmos |
| US7205148B2 (en) * | 2003-06-11 | 2007-04-17 | Regeneron Pharmaceuticals, Inc. | Genome mutation by intron insertion into an embryonic stem cell genome |
| WO2005084429A1 (ja) * | 2004-03-04 | 2005-09-15 | Cellseed Inc. | 癌細胞移植動物の製造方法 |
| WO2006004066A1 (ja) * | 2004-07-02 | 2006-01-12 | Locomogene, Inc. | S1-5を含有するタンパク質製剤 |
| JP4550530B2 (ja) * | 2004-09-03 | 2010-09-22 | 独立行政法人科学技術振興機構 | シナプス成熟障害モデル動物 |
| AU2006287315B2 (en) * | 2005-09-09 | 2013-02-21 | The Johns Hopkins University | Manipulation of regulatory T cell and DC function by targeting neuritin gene using antibodies, agonists and antagonists |
| AU2007262083B2 (en) * | 2006-06-20 | 2012-01-19 | Toray Industries, Inc. | Therapeutic or prophylactic agent for leukemia |
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2009
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- 2009-04-27 EP EP09734240A patent/EP2268821A1/en not_active Ceased
- 2009-04-27 CA CA2719267A patent/CA2719267A1/en not_active Abandoned
- 2009-04-27 AU AU2009240404A patent/AU2009240404A1/en not_active Abandoned
- 2009-04-27 JP JP2011506500A patent/JP2011518566A/ja active Pending
- 2009-04-27 WO PCT/US2009/041846 patent/WO2009132357A1/en not_active Ceased
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2010
- 2010-10-24 IL IL208904A patent/IL208904A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009132357A1 (en) | 2009-10-29 |
| JP2011518566A (ja) | 2011-06-30 |
| US8110719B2 (en) | 2012-02-07 |
| US20090271883A1 (en) | 2009-10-29 |
| AU2009240404A1 (en) | 2009-10-29 |
| IL208904A0 (en) | 2011-01-31 |
| EP2268821A1 (en) | 2011-01-05 |
| AU2009240404A2 (en) | 2010-12-02 |
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| FZDE | Discontinued |
Effective date: 20140429 |