JP2017505127A5 - - Google Patents

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JP2017505127A5
JP2017505127A5 JP2016548101A JP2016548101A JP2017505127A5 JP 2017505127 A5 JP2017505127 A5 JP 2017505127A5 JP 2016548101 A JP2016548101 A JP 2016548101A JP 2016548101 A JP2016548101 A JP 2016548101A JP 2017505127 A5 JP2017505127 A5 JP 2017505127A5
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Japan
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segment
cell
locus
cells
sequence
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JP2016548101A
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JP2017505127A (ja
JP6479024B2 (ja
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Priority claimed from PCT/US2015/012577 external-priority patent/WO2015112790A2/en
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JP2016548101A 2014-01-24 2015-01-23 抗体親和性の最適化のための高スループットマウスモデル Active JP6479024B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461931074P 2014-01-24 2014-01-24
US61/931,074 2014-01-24
PCT/US2015/012577 WO2015112790A2 (en) 2014-01-24 2015-01-23 High-throughput mouse model for optimizing antibody affinities

Publications (3)

Publication Number Publication Date
JP2017505127A JP2017505127A (ja) 2017-02-16
JP2017505127A5 true JP2017505127A5 (enExample) 2018-03-01
JP6479024B2 JP6479024B2 (ja) 2019-03-06

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JP2016548101A Active JP6479024B2 (ja) 2014-01-24 2015-01-23 抗体親和性の最適化のための高スループットマウスモデル

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US (2) US10034463B2 (enExample)
EP (1) EP3096609B1 (enExample)
JP (1) JP6479024B2 (enExample)
WO (1) WO2015112790A2 (enExample)

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EP4434589A3 (en) 2015-10-23 2025-05-14 President and Fellows of Harvard College Evolved cas9 proteins for gene editing
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WO2018204303A1 (en) 2017-05-01 2018-11-08 The Children's Medical Center Coporation Methods and compositions relating to anti-pd1 antibody reagents
US11560566B2 (en) 2017-05-12 2023-01-24 President And Fellows Of Harvard College Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and transcriptional activation
US11732274B2 (en) 2017-07-28 2023-08-22 President And Fellows Of Harvard College Methods and compositions for evolving base editors using phage-assisted continuous evolution (PACE)
WO2019139645A2 (en) 2017-08-30 2019-07-18 President And Fellows Of Harvard College High efficiency base editors comprising gam
KR20200121782A (ko) 2017-10-16 2020-10-26 더 브로드 인스티튜트, 인코퍼레이티드 아데노신 염기 편집제의 용도
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JP6479024B2 (ja) * 2014-01-24 2019-03-06 ザ チルドレンズ メディカル センター コーポレーション 抗体親和性の最適化のための高スループットマウスモデル

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