JP2017505127A5 - - Google Patents

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JP2017505127A5
JP2017505127A5 JP2016548101A JP2016548101A JP2017505127A5 JP 2017505127 A5 JP2017505127 A5 JP 2017505127A5 JP 2016548101 A JP2016548101 A JP 2016548101A JP 2016548101 A JP2016548101 A JP 2016548101A JP 2017505127 A5 JP2017505127 A5 JP 2017505127A5
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Japan
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segment
cell
locus
cells
sequence
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JP2016548101A
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JP6479024B2 (ja
JP2017505127A (ja
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Priority claimed from PCT/US2015/012577 external-priority patent/WO2015112790A2/en
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JP2016548101A 2014-01-24 2015-01-23 抗体親和性の最適化のための高スループットマウスモデル Active JP6479024B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461931074P 2014-01-24 2014-01-24
US61/931,074 2014-01-24
PCT/US2015/012577 WO2015112790A2 (en) 2014-01-24 2015-01-23 High-throughput mouse model for optimizing antibody affinities

Publications (3)

Publication Number Publication Date
JP2017505127A JP2017505127A (ja) 2017-02-16
JP2017505127A5 true JP2017505127A5 (enExample) 2018-03-01
JP6479024B2 JP6479024B2 (ja) 2019-03-06

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JP2016548101A Active JP6479024B2 (ja) 2014-01-24 2015-01-23 抗体親和性の最適化のための高スループットマウスモデル

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US (2) US10034463B2 (enExample)
EP (1) EP3096609B1 (enExample)
JP (1) JP6479024B2 (enExample)
WO (1) WO2015112790A2 (enExample)

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CN111801345A (zh) 2017-07-28 2020-10-20 哈佛大学的校长及成员们 使用噬菌体辅助连续进化(pace)的进化碱基编辑器的方法和组合物
EP3676376B1 (en) 2017-08-30 2025-01-15 President and Fellows of Harvard College High efficiency base editors comprising gam
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WO2015112790A2 (en) * 2014-01-24 2015-07-30 Children's Medical Center Corporation High-throughput mouse model for optimizing antibody affinities

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