JP2011515236A - 制御された濡れ特性を有するマイクロ流体チャネルを含む表面 - Google Patents

制御された濡れ特性を有するマイクロ流体チャネルを含む表面 Download PDF

Info

Publication number
JP2011515236A
JP2011515236A JP2011501785A JP2011501785A JP2011515236A JP 2011515236 A JP2011515236 A JP 2011515236A JP 2011501785 A JP2011501785 A JP 2011501785A JP 2011501785 A JP2011501785 A JP 2011501785A JP 2011515236 A JP2011515236 A JP 2011515236A
Authority
JP
Japan
Prior art keywords
sol
gel
article
coating
microfluidic channel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011501785A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011515236A5 (https=
Inventor
アダム アール． アバテ，
アンバー ティー． クルーメル，
クリスティアン ホルツェ，
デイビッド エー． ウェイツ，
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Harvard University
Original Assignee
Harvard University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard University filed Critical Harvard University
Publication of JP2011515236A publication Critical patent/JP2011515236A/ja
Publication of JP2011515236A5 publication Critical patent/JP2011515236A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
    • F16L9/00—Rigid pipes
    • F16L9/14—Compound tubes, i.e. made of materials not wholly covered by any one of the preceding groups
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C1/00—Manufacture or treatment of devices or systems in or on a substrate
    • B81C1/00015—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems
    • B81C1/00206—Processes for functionalising a surface, e.g. provide the surface with specific mechanical, chemical or biological properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/301—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions
    • B01F33/3011—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions using a sheathing stream of a fluid surrounding a central stream of a different fluid, e.g. for reducing the cross-section of the central stream or to produce droplets from the central stream
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00614—Delimitation of the attachment areas
    • B01J2219/00617—Delimitation of the attachment areas by chemical means
    • B01J2219/00619—Delimitation of the attachment areas by chemical means using hydrophilic or hydrophobic regions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00632—Introduction of reactive groups to the surface
    • B01J2219/00635—Introduction of reactive groups to the surface by reactive plasma treatment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B01J2219/00632—Introduction of reactive groups to the surface
    • B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2201/00—Specific applications of microelectromechanical systems
    • B81B2201/05—Microfluidics
    • B81B2201/058—Microfluidics not provided for in B81B2201/051 - B81B2201/054
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2203/00—Basic microelectromechanical structures
    • B81B2203/03—Static structures
    • B81B2203/0323—Grooves
    • B81B2203/0338—Channels

Landscapes

  • Engineering & Computer Science (AREA)
  • Manufacturing & Machinery (AREA)
  • General Engineering & Computer Science (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Micromachines (AREA)
  • Laminated Bodies (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Coating Of Shaped Articles Made Of Macromolecular Substances (AREA)
JP2011501785A 2008-03-28 2009-02-11 制御された濡れ特性を有するマイクロ流体チャネルを含む表面 Pending JP2011515236A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4044208P 2008-03-28 2008-03-28
US61/040,442 2008-03-28
PCT/US2009/000850 WO2009120254A1 (en) 2008-03-28 2009-02-11 Surfaces, including microfluidic channels, with controlled wetting properties

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013238441A Division JP2014088027A (ja) 2008-03-28 2013-11-19 制御された濡れ特性を有するマイクロ流体チャネルを含む表面

Publications (2)

Publication Number Publication Date
JP2011515236A true JP2011515236A (ja) 2011-05-19
JP2011515236A5 JP2011515236A5 (https=) 2013-04-04

Family

ID=41114238

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2011501785A Pending JP2011515236A (ja) 2008-03-28 2009-02-11 制御された濡れ特性を有するマイクロ流体チャネルを含む表面
JP2013238441A Pending JP2014088027A (ja) 2008-03-28 2013-11-19 制御された濡れ特性を有するマイクロ流体チャネルを含む表面

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2013238441A Pending JP2014088027A (ja) 2008-03-28 2013-11-19 制御された濡れ特性を有するマイクロ流体チャネルを含む表面

Country Status (4)

Country Link
US (2) US8802027B2 (https=)
EP (1) EP2271581A4 (https=)
JP (2) JP2011515236A (https=)
WO (1) WO2009120254A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022519200A (ja) * 2019-01-31 2022-03-22 サンプリックス エーピーエス マイクロ流体デバイスおよびダブルエマルション液滴の提供のための方法

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2248578B1 (en) 2005-03-04 2012-06-06 President and Fellows of Harvard College Method for forming multiple emulsions
US8883291B2 (en) * 2007-08-07 2014-11-11 President And Fellows Of Harvard College Metal oxide coating on surfaces
JP2011515236A (ja) * 2008-03-28 2011-05-19 プレジデント アンド フェローズ オブ ハーバード カレッジ 制御された濡れ特性を有するマイクロ流体チャネルを含む表面
US20110218123A1 (en) 2008-09-19 2011-09-08 President And Fellows Of Harvard College Creation of libraries of droplets and related species
WO2010104604A1 (en) 2009-03-13 2010-09-16 President And Fellows Of Harvard College Method for the controlled creation of emulsions, including multiple emulsions
JP5841937B2 (ja) 2009-06-26 2016-01-13 プレジデント アンド フェローズ オブ ハーバード カレッジ 流体注入
GB2471522B (en) * 2009-07-03 2014-01-08 Cambridge Entpr Ltd Microfluidic devices
US20120211084A1 (en) * 2009-09-02 2012-08-23 President And Fellows Of Harvard College Multiple emulsions created using jetting and other techniques
KR20120089662A (ko) * 2009-09-02 2012-08-13 바스프 에스이 연접을 이용하여 생성된 다중 에멀젼
US8486534B2 (en) * 2010-06-08 2013-07-16 Bar-Ilan University Surface-modified polymer films
US20120167410A1 (en) * 2010-12-21 2012-07-05 Basf Se Spray drying techniques
KR20140063507A (ko) 2011-02-07 2014-05-27 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 액적을 분할하기 위한 시스템 및 방법
AU2012236713B2 (en) * 2011-03-30 2016-11-24 Bio-Rad Laboratories, Inc. Injection of multiple volumes into or out of droplets
EP2714254B1 (en) 2011-05-23 2017-09-06 President and Fellows of Harvard College Control of emulsions, including multiple emulsions
BR112014000141A2 (pt) 2011-07-06 2017-06-13 Harvard College emulsões múltiplas e técnicas para a formação de emulsões múltiplas
BR112014004554A2 (pt) 2011-08-30 2017-04-04 Basf Se sistemas e processos para encapsulamento de cápsulas
WO2013176767A1 (en) 2012-05-25 2013-11-28 The University Of North Carolina At Chapel Hill Microfluidic devices, solid supports for reagents and related methods
WO2013181506A1 (en) 2012-05-31 2013-12-05 The University Of North Carolina At Chapel Hill Dissolution guided wetting of structured surfaces
US9211521B2 (en) 2012-09-19 2015-12-15 Millifluidica, Llc Fluidic channel coated with metal catalysts and devices and methods relating thereto
JP2016502632A (ja) 2012-09-21 2016-01-28 プレジデント アンド フェローズ オブ ハーバード カレッジ マイクロ流体用および他のシステムにおける噴霧乾燥のためのシステムおよび方法
US9636673B2 (en) * 2013-03-01 2017-05-02 Micronit Microfluidics B.V. Method for manufacturing microfluidic chips, device for functionalizing microfluidic chips, microfluidic chip and device for holding a microfluidic chip
JP2016514047A (ja) 2013-03-06 2016-05-19 プレジデント アンド フェローズ オブ ハーバード カレッジ 比較的単分散の液滴を形成するためのデバイスおよび方法
WO2014201196A2 (en) 2013-06-14 2014-12-18 President And Fellows Of Harvard College Coalescence of droplets
EP3065712A4 (en) 2013-11-08 2017-06-21 President and Fellows of Harvard College Microparticles, methods for their preparation and use
WO2015160919A1 (en) 2014-04-16 2015-10-22 President And Fellows Of Harvard College Systems and methods for producing droplet emulsions with relatively thin shells
CA2966317A1 (en) * 2014-10-30 2016-05-06 Beckman Coulter, Inc. Compositions and methods for coating surfaces
CN106999893B (zh) 2014-11-24 2020-07-14 宝洁公司 用于将活性物质包封于液滴和其它隔室内的方法
CA3001679A1 (en) 2015-10-13 2017-04-20 President And Fellows Of Harvard College Systems and methods for making and using gel microspheres
US12345708B2 (en) 2016-03-25 2025-07-01 President And Fellows Of Harvard College Microfluidic determination of immune and other cells
WO2017174610A1 (en) 2016-04-05 2017-10-12 Universite De Strasbourg Intra-droplet surface engineering to capture a molecular target
JP2019514002A (ja) 2016-04-15 2019-05-30 プレジデント アンド フェローズ オブ ハーバード カレッジ 液滴および／または他の実体の収集のためのシステムおよび方法
KR102415046B1 (ko) * 2016-08-08 2022-06-29 쉬르픽스 베붸 고체 표면의 개질 방법
JP7039575B2 (ja) * 2016-09-30 2022-03-22 アモーレパシフィック コーポレーション マイクロ流体チャネルに基づいて瞬時に乳化された乳化物を含有する化粧品組成物調製装置
JP7063541B2 (ja) * 2017-03-31 2022-05-09 住友理工株式会社 流体デバイス用シリコーン部材およびその製造方法
US20210187508A1 (en) 2017-10-16 2021-06-24 1 CellBio ,Inc. Systems and methods for particulate encapsulation in microdroplets
WO2019110590A1 (en) 2017-12-06 2019-06-13 Samplix Aps A microfluidic device and a method for provision of double emulsion droplets
US11618023B2 (en) 2017-12-06 2023-04-04 Samplix Aps Microfluidic device and a method for provision of emulsion droplets
US11103867B2 (en) 2017-12-13 2021-08-31 International Business Machines Corporation Localized surface modification for microfluidic applications
EP3794080B1 (en) 2018-05-18 2024-04-10 The University of North Carolina at Chapel Hill Compositions, devices, and methods for improving a surface property of a substrate
AU2020215103B2 (en) 2019-01-31 2025-07-17 Samplix Aps A microfluidic device and a method for provision of emulsion droplets
CN111632581B (zh) * 2019-03-01 2021-04-13 江南大学 一种仿树莓状超疏水亲油棉纤维油水吸附/分离膜及其制备方法和应用
AU2020361681A1 (en) 2019-10-10 2022-05-05 1859, Inc. Methods and systems for microfluidic screening
US20230184353A1 (en) * 2021-12-15 2023-06-15 Cooper-Standard Automotive Inc. Abrasion resistant coated tube
US20240182849A1 (en) 2022-11-07 2024-06-06 Shennon Biotechnologies Inc. Microfluidic Devices for High Throughput Screening of Cell-Cell Interactions

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002086399A (ja) * 2000-06-20 2002-03-26 Kawamura Inst Of Chem Res 積層構造を有するマイクロデバイス及びその製造方法
JP2003136500A (ja) * 2001-11-02 2003-05-14 Kawamura Inst Of Chem Res 樹脂ダイヤフラムを有するマイクロ流体デバイスの製造方法
JP2003230829A (ja) * 2001-12-06 2003-08-19 Hitachi Ltd 平面マイクロファクトリー
JP2004125475A (ja) * 2002-09-30 2004-04-22 Nippon Sheet Glass Co Ltd 液体制御機構、該液体制御機構を備えた光スイッチバイオセンサ及び光スイッチポンプ部品
JP2005103423A (ja) * 2003-09-30 2005-04-21 Fuji Kagaku Kk マイクロ化学デバイス
JP2005519264A (ja) * 2002-02-27 2005-06-30 サード・ウェーブ・テクノロジーズ・インク 表面修飾、リンカー結合、および重合方法
JP2005331286A (ja) * 2004-05-18 2005-12-02 Nippon Kayaku Co Ltd マイクロ化学デバイス
WO2006027757A2 (en) * 2004-09-09 2006-03-16 Institut Curie Microfluidic device using a collinear electric field
JP2007538226A (ja) * 2003-06-30 2007-12-27 ロウステック プロプライエタリー リミテッド 空間的に選択的なマイクロ及びナノメートルスケールの付着用の基体及びコンビナトリアル修正及び成形加工
JP2008530317A (ja) * 2005-02-15 2008-08-07 アールピーオー プロプライエタリー リミテッド ポリマー材料のフォトリソグラフィックパターニング
JP2008284626A (ja) * 2007-05-16 2008-11-27 Miraial Kk マイクロ流路デバイス

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6176962B1 (en) * 1990-02-28 2001-01-23 Aclara Biosciences, Inc. Methods for fabricating enclosed microchannel structures
US5512131A (en) 1993-10-04 1996-04-30 President And Fellows Of Harvard College Formation of microstamped patterns on surfaces and derivative articles
WO1996029629A2 (en) 1995-03-01 1996-09-26 President And Fellows Of Harvard College Microcontact printing on surfaces and derivative articles
EP0949277A3 (en) 1995-06-22 2000-12-27 Yuri Gudimenko Surface modification of polymers and carbon-based materials
US6355198B1 (en) 1996-03-15 2002-03-12 President And Fellows Of Harvard College Method of forming articles including waveguides via capillary micromolding and microtransfer molding
US6016689A (en) * 1996-11-18 2000-01-25 The Research Foundation Of Suny At Buffalo Aerosol-generated sol-gel derived thin films and applications thereof
US6391622B1 (en) 1997-04-04 2002-05-21 Caliper Technologies Corp. Closed-loop biochemical analyzers
US6576478B1 (en) 1998-07-14 2003-06-10 Zyomyx, Inc. Microdevices for high-throughput screening of biomolecules
US6103199A (en) * 1998-09-15 2000-08-15 Aclara Biosciences, Inc. Capillary electroflow apparatus and method
TW421670B (en) 1999-04-02 2001-02-11 Ind Tech Res Inst Fast-cured sol materials
US6645432B1 (en) 2000-05-25 2003-11-11 President & Fellows Of Harvard College Microfluidic systems including three-dimensionally arrayed channel networks
JP3985887B2 (ja) 2000-05-31 2007-10-03 日本カーリット株式会社 金属酸化物前駆体溶液
WO2003053577A1 (en) * 2001-12-21 2003-07-03 Nippon Sheet Glass Co., Ltd. Member having photocatalytic function and method for manufacture thereof
US20030148291A1 (en) * 2002-02-05 2003-08-07 Karla Robotti Method of immobilizing biologically active molecules for assay purposes in a microfluidic format
US7393693B2 (en) * 2002-05-31 2008-07-01 Agilent Technologies, Inc. Methods and procedures for stabilization and performance optimization of multi-layer sol-gel chemical and biochemical sensors
AU2003243505A1 (en) 2002-06-11 2003-12-22 University Of Virginia Patent Foundation Apparatus and method for the purification of nucleic acids
JP2006507921A (ja) 2002-06-28 2006-03-09 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 流体分散のための方法および装置
KR100480338B1 (ko) * 2002-08-08 2005-03-30 한국전자통신연구원 극소량의 유체제어를 위한 미세 유체제어소자
WO2004067444A1 (en) 2003-01-30 2004-08-12 Gyros Ab Inner walls of microfluidic devices
WO2004081536A2 (en) 2003-03-12 2004-09-23 Arizona Board Of Regents Radical activated cleavage of biologics and microfluidic devices using the same
EP2127736A1 (en) 2003-04-10 2009-12-02 The President and Fellows of Harvard College Formation and control of fluidic species
US20050127002A1 (en) * 2003-12-12 2005-06-16 Zare Richard N. Immobilized-enzyme microreactor devices for characterization of biomolecular analytes and associated methods
EP1547675A1 (en) 2003-12-24 2005-06-29 Corning Incorporated Coated microstructures and methods of coating same
US7695775B2 (en) 2004-06-04 2010-04-13 Applied Microstructures, Inc. Controlled vapor deposition of biocompatible coatings over surface-treated substrates
KR100637416B1 (ko) 2004-10-25 2006-10-23 주식회사 에코솔루션 표면개질된 실리카 나노입자와 피디엠에스를 이용하여 제조된 휘발성유기화합물 분리용 혼합 막, 이의 제조방법 및 용도
US7381633B2 (en) 2005-01-27 2008-06-03 Hewlett-Packard Development Company, L.P. Method of making a patterned metal oxide film
AU2006210267A1 (en) * 2005-02-03 2006-08-10 Cinvention Ag Drug delivery materials made by sol/gel technology
EP2248578B1 (en) 2005-03-04 2012-06-06 President and Fellows of Harvard College Method for forming multiple emulsions
US20070054119A1 (en) 2005-03-04 2007-03-08 Piotr Garstecki Systems and methods of forming particles
US20070005024A1 (en) 2005-06-10 2007-01-04 Jan Weber Medical devices having superhydrophobic surfaces, superhydrophilic surfaces, or both
JP2006349060A (ja) 2005-06-16 2006-12-28 Ntn Corp ボールねじ
JP2007033167A (ja) * 2005-07-26 2007-02-08 Kagawa Univ バイオケミカルチップとその製造方法
US7651762B2 (en) * 2007-03-13 2010-01-26 Varian, Inc. Methods and devices using a shrinkable support for porous monolithic materials
US7776927B2 (en) 2007-03-28 2010-08-17 President And Fellows Of Harvard College Emulsions and techniques for formation
US8883291B2 (en) 2007-08-07 2014-11-11 President And Fellows Of Harvard College Metal oxide coating on surfaces
JP2011515236A (ja) 2008-03-28 2011-05-19 プレジデント アンド フェローズ オブ ハーバード カレッジ 制御された濡れ特性を有するマイクロ流体チャネルを含む表面

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002086399A (ja) * 2000-06-20 2002-03-26 Kawamura Inst Of Chem Res 積層構造を有するマイクロデバイス及びその製造方法
JP2003136500A (ja) * 2001-11-02 2003-05-14 Kawamura Inst Of Chem Res 樹脂ダイヤフラムを有するマイクロ流体デバイスの製造方法
JP2003230829A (ja) * 2001-12-06 2003-08-19 Hitachi Ltd 平面マイクロファクトリー
JP2005519264A (ja) * 2002-02-27 2005-06-30 サード・ウェーブ・テクノロジーズ・インク 表面修飾、リンカー結合、および重合方法
JP2004125475A (ja) * 2002-09-30 2004-04-22 Nippon Sheet Glass Co Ltd 液体制御機構、該液体制御機構を備えた光スイッチバイオセンサ及び光スイッチポンプ部品
JP2007538226A (ja) * 2003-06-30 2007-12-27 ロウステック プロプライエタリー リミテッド 空間的に選択的なマイクロ及びナノメートルスケールの付着用の基体及びコンビナトリアル修正及び成形加工
JP2005103423A (ja) * 2003-09-30 2005-04-21 Fuji Kagaku Kk マイクロ化学デバイス
JP2005331286A (ja) * 2004-05-18 2005-12-02 Nippon Kayaku Co Ltd マイクロ化学デバイス
WO2006027757A2 (en) * 2004-09-09 2006-03-16 Institut Curie Microfluidic device using a collinear electric field
JP2008530317A (ja) * 2005-02-15 2008-08-07 アールピーオー プロプライエタリー リミテッド ポリマー材料のフォトリソグラフィックパターニング
JP2008284626A (ja) * 2007-05-16 2008-11-27 Miraial Kk マイクロ流路デバイス

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022519200A (ja) * 2019-01-31 2022-03-22 サンプリックス エーピーエス マイクロ流体デバイスおよびダブルエマルション液滴の提供のための方法
JP7231748B2 (ja) 2019-01-31 2023-03-01 サンプリックス エーピーエス マイクロ流体デバイスおよびダブルエマルション液滴の提供のための方法

Also Published As

Publication number Publication date
EP2271581A1 (en) 2011-01-12
US20110123413A1 (en) 2011-05-26
WO2009120254A1 (en) 2009-10-01
US8802027B2 (en) 2014-08-12
US20140150916A1 (en) 2014-06-05
JP2014088027A (ja) 2014-05-15
EP2271581A4 (en) 2014-09-03

Similar Documents

Publication Publication Date Title
JP2011515236A (ja) 制御された濡れ特性を有するマイクロ流体チャネルを含む表面
Abate et al. Photoreactive coating for high-contrast spatial patterning of microfluidic device wettability
JP2013503742A (ja) ジャンクションを使用して生成された多重エマルジョン
Kim et al. Solvent‐resistant PDMS microfluidic devices with hybrid inorganic/organic polymer coatings
EP1576040B1 (en) Patterned polymeric structures, particularly microstructures, and methods for making same
Credi et al. Stereolithography of perfluoropolyethers for the microfabrication of robust omniphobic surfaces
WO2005072235A2 (en) Structured materials and methods
JP2010069730A (ja) ナノインプリントリソグラフィー用の高耐久性レプリカモールドおよびその作製方法
TW201819044A (zh) 壓印基板
Abate et al. Functionalized glass coating for PDMS microfluidic devices
Huyen et al. Flexible capillary microfluidic devices based on surface-energy modified polydimethylsiloxane and polymethylmethacrylate with room-temperature chemical bonding
Choonee et al. Post processing of microstructures by PDMS spray deposition
Ford et al. Growing “nanofruit” textures on photo-crosslinked SU-8 surfaces through layer-by-layer grafting of hyperbranched poly (ethyleneimine)
Malecha et al. A PDMS/LTCC bonding technique for microfluidic application
Hirama et al. Surface modification of a glass microchannel for the formation of multiple emulsion droplets
Carvalho et al. Local light-induced modification of the inside of microfluidic glass chips
Arayanarakool et al. A new method of UV-patternable hydrophobization of micro-and nanofluidic networks
KR20080021104A (ko) 무기고분자 및 친수성 고분자를 이용한 미세·나노유체 소자및 ｍｅｍｓ 미세구조물 제조 방법
CN111936442B (zh) 修饰固体表面的方法
KR100837806B1 (ko) 무기고분자 및 친수성 고분자를 이용한 미세·나노유체 소자및 ｍｅｍｓ 미세구조물 제조 방법
KR20070111922A (ko) 무기고분자 및 친수성 고분자를 이용한 미세·나노유체 소자및 ｍｅｍｓ 미세구조물 제조 방법
Abbas et al. Capillary microchannel fabrication using plasma polymerized TMDS for fluidic MEMS technology
Suhard et al. When energetic materials, PDMS-based elastomers, and microelectronic processes work together: fabrication of a disposable microactuator
Bou et al. Microfluidic devices using thiol-ene polymers
Hozumi et al. Spatially defined immobilization of biomolecules on microstructured polymer substrate

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120208

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20120208

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130208

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20130620

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130625

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20130924

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20131001

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20131119

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20140326

RD03 Notification of appointment of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7423

Effective date: 20140401

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20140401

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20140425

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20140625

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20140702

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140717

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20140826