BR112014004554A2 - sistemas e processos para encapsulamento de cápsulas - Google Patents

sistemas e processos para encapsulamento de cápsulas

Info

Publication number
BR112014004554A2
BR112014004554A2 BR112014004554A BR112014004554A BR112014004554A2 BR 112014004554 A2 BR112014004554 A2 BR 112014004554A2 BR 112014004554 A BR112014004554 A BR 112014004554A BR 112014004554 A BR112014004554 A BR 112014004554A BR 112014004554 A2 BR112014004554 A2 BR 112014004554A2
Authority
BR
Brazil
Prior art keywords
particles
shell
agent
processes
particle
Prior art date
Application number
BR112014004554A
Other languages
English (en)
Inventor
Sun Bingjie
Holtze Christian
A Weitz David
Cheung Shum Ho
Zhao Yuanjin
Original Assignee
Basf Se
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se, Harvard College filed Critical Basf Se
Publication of BR112014004554A2 publication Critical patent/BR112014004554A2/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/20—After-treatment of capsule walls, e.g. hardening
    • B01J13/203—Exchange of core-forming material by diffusion through the capsule wall
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
    • A01N25/28—Microcapsules or nanocapsules
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/015—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/501—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B67/00—Influencing the physical, e.g. the dyeing or printing properties of dyestuffs without chemical reactions, e.g. by treating with solvents grinding or grinding assistants, coating of pigments or dyes; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
    • C09B67/0097—Dye preparations of special physical nature; Tablets, films, extrusion, microcapsules, sheets, pads, bags with dyes
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
    • C11D17/0039—Coated compositions or coated components in the compositions, (micro)capsules

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Wood Science & Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Environmental Sciences (AREA)
  • Toxicology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Nutrition Science (AREA)
  • Agronomy & Crop Science (AREA)
  • Dispersion Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

resumo patente de invenção: "sistemas e processos para encapsulamento de cápsulas". a presente invenção refere-se de forma geral a partículas, incluindo partículas para fornecimento de fármacos e outras aplicações. certos aspectos da invenção são geralmente direcionados a partículas que compreendem um invólucro e um interior pelo menos parcialmente contido pelo invólucro. em algumas modalidades, as partículas podem ser tratadas para aumentar a retenção do interior, por exemplo, para reduzir o transporte de um agente para dentro ou para fora do interior. tais partículas podem exibir maior capacidade de encapsular agentes e/ou maior vida de armazenamento (por exemplo, devido ao vazamento reduzido). por exemplo, em certas modalidades, quaisquer defeitos, tais como rachaduras, poros etc. dentro do invólucro podem ser selados ou de outra maneira tratados para reduzir o transporte através do mesmo, por exemplo, com um sólido. em algumas modalidades, por exemplo, um primeiro reagente no interior de uma partícula pode entrar em contato com um segundo reagente fora da partícula para formar um sólido ou outro produto adequado. o invólucro também pode ser tratado, por exemplo, em um ponto no tempo posterior, para causar a liberação de um agente contido dentro do interior, em certos aspectos. por exemplo, o invólucro pode ser aquecido para causar a liberação do agente partindo da partícula ou o invólucro pode ser exposto à degradação química ou enzimática ou a uma alteração na osmolaridade, para causar a liberação de um agente. ainda outros aspectos da presente invenção são geralmente direcionados a processos de produção ou de utilização de tais partículas, kits ou dispositivos que incluem tais partículas ou similar.
BR112014004554A 2011-08-30 2012-08-15 sistemas e processos para encapsulamento de cápsulas BR112014004554A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161529126P 2011-08-30 2011-08-30
PCT/US2012/050916 WO2013032709A2 (en) 2011-08-30 2012-08-15 Systems and methods for shell encapsulation

Publications (1)

Publication Number Publication Date
BR112014004554A2 true BR112014004554A2 (pt) 2017-04-04

Family

ID=46750496

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014004554A BR112014004554A2 (pt) 2011-08-30 2012-08-15 sistemas e processos para encapsulamento de cápsulas

Country Status (6)

Country Link
US (1) US20130064862A1 (pt)
EP (1) EP2750787A2 (pt)
JP (1) JP2014529625A (pt)
CN (1) CN103764272A (pt)
BR (1) BR112014004554A2 (pt)
WO (1) WO2013032709A2 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9039273B2 (en) * 2005-03-04 2015-05-26 President And Fellows Of Harvard College Method and apparatus for forming multiple emulsions
US20110218123A1 (en) 2008-09-19 2011-09-08 President And Fellows Of Harvard College Creation of libraries of droplets and related species
BR112012004719A2 (pt) * 2009-09-02 2016-04-05 Harvard College emulsões múltiplas criadas por uso de jateamento e outras técnicas
EP2547436A2 (en) * 2010-03-17 2013-01-23 President and Fellows of Harvard College Melt emulsification
EP2714254B1 (en) 2011-05-23 2017-09-06 President and Fellows of Harvard College Control of emulsions, including multiple emulsions
JP2014522718A (ja) 2011-07-06 2014-09-08 プレジデント アンド フェローズ オブ ハーバード カレッジ 多相エマルションおよび多相エマルション形成法
JP2015018993A (ja) * 2013-07-12 2015-01-29 富士通株式会社 電子装置
US20160279068A1 (en) * 2013-11-08 2016-09-29 President And Fellows Of Harvard College Microparticles, methods for their preparation and use
WO2015160919A1 (en) 2014-04-16 2015-10-22 President And Fellows Of Harvard College Systems and methods for producing droplet emulsions with relatively thin shells
RU2017114553A (ru) 2014-11-24 2018-12-26 Дзе Проктер Энд Гэмбл Компани Композиции, содержащие активные агенты, инкапсулированные в капли и другие полости
WO2017015617A1 (en) 2015-07-23 2017-01-26 New York University Self-inflating microcapsules
AU2016338907B2 (en) 2015-10-13 2022-07-07 President And Fellows Of Harvard College Systems and methods for making and using gel microspheres
FR3064193B1 (fr) * 2017-03-21 2021-04-30 Calyxia Procede de preparation de capsules avec des proprietes de retention ameliorees et capsules obtenues
US10408852B2 (en) 2017-04-26 2019-09-10 Lawrence Livermore National Security, Llc Automated control of microfluidic devices based on machine learning
WO2023117364A1 (en) 2021-12-01 2023-06-29 Vilnius University A microcapsule and methods of making and using same
WO2023099661A1 (en) 2021-12-01 2023-06-08 Vilnius University Microcapsules comprising biological samples, and methods for use of same

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5857973B2 (ja) * 1978-02-13 1983-12-22 ぺんてる株式会社 無機質壁マイクロカプセルの製造方法
JPS6157236A (ja) * 1984-08-29 1986-03-24 Agency Of Ind Science & Technol 含油無機質壁マイクロカプセル及びその製造方法
ITRM980488A1 (it) * 1998-07-23 2000-01-23 Nyl Service S R L Capsule autosigillanti e procedimento per la loro produzione
DE10035302C2 (de) * 2000-07-18 2002-12-19 Deotexis Inc Mikrokapsel, Verfahren zu ihrer Herstellung und Verwendung derselben
JP2006507921A (ja) 2002-06-28 2006-03-09 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 流体分散のための方法および装置
JP5285201B2 (ja) * 2002-09-25 2013-09-11 株式会社ナノエッグ レチノイン酸ナノカプセル
CA2521862C (en) 2003-04-10 2012-10-16 President And Fellows Of Harvard College Formation and control of fluidic species
EP2662136A3 (en) 2003-08-27 2013-12-25 President and Fellows of Harvard College Method for handling and mixing droplets
CN100464833C (zh) * 2004-11-11 2009-03-04 中国科学院化学研究所 用模板法制备中空球和复合结构的中空球的方法
US9039273B2 (en) * 2005-03-04 2015-05-26 President And Fellows Of Harvard College Method and apparatus for forming multiple emulsions
US8865798B2 (en) * 2006-10-17 2014-10-21 Valorbec Societe En Commandite Self healing composite material and method of manufacturing same
US7776927B2 (en) 2007-03-28 2010-08-17 President And Fellows Of Harvard College Emulsions and techniques for formation
WO2009075652A1 (en) * 2007-12-11 2009-06-18 Nanyang Technological University Hollow multi-layered microspheres for delivery of hydrophilic active compounds
US8802027B2 (en) 2008-03-28 2014-08-12 President And Fellows Of Harvard College Surfaces, including microfluidic channels, with controlled wetting properties
WO2010104604A1 (en) 2009-03-13 2010-09-16 President And Fellows Of Harvard College Method for the controlled creation of emulsions, including multiple emulsions
CN101856603A (zh) * 2009-04-09 2010-10-13 美国吉姆迪生物科技有限公司 透明质酸的纳米/微封装和释放
BR112012004719A2 (pt) 2009-09-02 2016-04-05 Harvard College emulsões múltiplas criadas por uso de jateamento e outras técnicas
EP2473262A4 (en) 2009-09-02 2015-12-02 Harvard College MULTIPLE EMULSIONS MADE FROM COMPOUNDS
JP5589347B2 (ja) * 2009-10-29 2014-09-17 国立大学法人 新潟大学 複合膜シェルマイクロカプセルの製造方法
CN101721964A (zh) * 2009-11-12 2010-06-09 同济大学 一种防功能性物质泄露的核壳微/纳米球的制备方法

Also Published As

Publication number Publication date
WO2013032709A2 (en) 2013-03-07
CN103764272A (zh) 2014-04-30
JP2014529625A (ja) 2014-11-13
WO2013032709A3 (en) 2013-12-27
US20130064862A1 (en) 2013-03-14
EP2750787A2 (en) 2014-07-09

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B15K Others concerning applications: alteration of classification

Ipc: B01J 13/20 (2006.01), A01N 25/28 (2006.01), A23L 2

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2475 DE 12-06-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.