JP2011511053A5 - - Google Patents

Download PDF

Info

Publication number
JP2011511053A5
JP2011511053A5 JP2010545562A JP2010545562A JP2011511053A5 JP 2011511053 A5 JP2011511053 A5 JP 2011511053A5 JP 2010545562 A JP2010545562 A JP 2010545562A JP 2010545562 A JP2010545562 A JP 2010545562A JP 2011511053 A5 JP2011511053 A5 JP 2011511053A5
Authority
JP
Japan
Prior art keywords
vorinostat
iii
haloformate
treating
hydroxylamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2010545562A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011511053A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/GB2009/050117 external-priority patent/WO2009098515A1/en
Publication of JP2011511053A publication Critical patent/JP2011511053A/ja
Publication of JP2011511053A5 publication Critical patent/JP2011511053A5/ja
Withdrawn legal-status Critical Current

Links

JP2010545562A 2008-02-07 2009-02-06 ボリノスタットの新規な製造方法 Withdrawn JP2011511053A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN220KO2008 2008-02-07
PCT/GB2009/050117 WO2009098515A1 (en) 2008-02-07 2009-02-06 Novel process for the preparation of vorinostat

Publications (2)

Publication Number Publication Date
JP2011511053A JP2011511053A (ja) 2011-04-07
JP2011511053A5 true JP2011511053A5 (enExample) 2012-03-22

Family

ID=40637203

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010545562A Withdrawn JP2011511053A (ja) 2008-02-07 2009-02-06 ボリノスタットの新規な製造方法

Country Status (8)

Country Link
US (1) US20110039937A1 (enExample)
EP (1) EP2240436A1 (enExample)
JP (1) JP2011511053A (enExample)
CN (1) CN101939289A (enExample)
AU (1) AU2009211157A1 (enExample)
CA (1) CA2712858A1 (enExample)
NZ (1) NZ586955A (enExample)
WO (1) WO2009098515A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ592686A (en) * 2008-10-15 2012-12-21 Generics Uk Ltd Process for the preparation of vorinostat from aniline, hydroxylamine and suberic acid starting materials
CN102282126A (zh) 2008-11-26 2011-12-14 基因里克斯(英国)有限公司 多晶型物
CN103018346A (zh) * 2011-09-20 2013-04-03 北京本草天源药物研究院 伏立诺他及其药物组合物中的杂质的高效液相色谱分析方法
CN103922967B (zh) * 2014-04-15 2016-06-01 北京化工大学 一种异羟肟酸类化合物及其在制备抑制癌细胞增殖和/或治疗癌症的药物中的应用
CN109096148B (zh) * 2018-10-16 2021-04-20 新昌县勤勉生物医药科技有限公司 利用改性介孔材料一锅法制备伏立诺他的方法
CN113943232A (zh) * 2021-11-25 2022-01-18 汤斌 一种从大鲵肽中提取伏立诺他的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5369108A (en) * 1991-10-04 1994-11-29 Sloan-Kettering Institute For Cancer Research Potent inducers of terminal differentiation and methods of use thereof
US5545665A (en) * 1993-12-28 1996-08-13 Allergan Cyclopentane(ene) heptenoic or heptanoic acids and derivatives thereof useful as therapeutic agents
EP1541549A1 (en) 2003-12-12 2005-06-15 Exonhit Therapeutics S.A. Tricyclic hydroxamate and benzaminde derivatives, compositions and methods

Similar Documents

Publication Publication Date Title
JP5629214B2 (ja) 2−メチル−2′−フェニルプロピオン酸誘導体の製造方法およびこれに使用される新規な中間体化合物
JP2011511053A5 (enExample)
JP6488359B2 (ja) ベンズイミダゾール誘導体の製造方法
EP3044212A1 (en) Process for the large scale production of 1h- [1,2,3]triazole and its intermediate 1-benzyl-1h-[1,2,3]triazole
ES2694512T3 (es) Procedimiento mejorado para la preparación de pomalidomida y su purificación
CN101300232A (zh) 合成取代的吡唑的方法
WO2017190609A1 (zh) 一种高效合成西他沙星中间体(7s)-5-氮杂螺[2.4]庚烷-7-基氨基甲酸叔丁酯的制备方法
US20160355533A1 (en) Crystalline Fosaprepitant Dicyclohexylamine Salt And Its Preparation
WO2009098515A1 (en) Novel process for the preparation of vorinostat
KR101032600B1 (ko) 고순도 레바미피드의 제조방법
US9630909B2 (en) Process for the preparation of nepafenac
NO20070635L (no) Faste former av magnesiumsalt av S-omeprazol og fremgangsmater for deres fremstilling
WO2012117410A1 (en) A process for the preparation of n-[2-[(acetylthio) methyl]-1-oxo-3-phenylpropyl] glycine phenyl methyl ester and intermediates thereof
WO2023082574A1 (zh) 一种塞拉菌素的合成方法
JP5704763B2 (ja) トランス−4−アミノシクロペンタ−2−エン−1−カルボン酸誘導体の製造
CN101759716A (zh) 一种水溶性截短侧耳素类化合物的制备方法及其中间体
CN101033198A (zh) N-取代-2,4-二氯-5-氟苯甲酰胺及其制备与应用
JP5009736B2 (ja) 環状アミノエーテルを用いたマンニッヒ反応
CN102491919B (zh) 去甲维拉帕米的合成方法
KR20160061542A (ko) 새로운 루리코나졸 이성체 분리 방법
Hamadi et al. Synthesis of new pyrazolines and their biological evaluation as antimicrobial agents
CN110590768B (zh) 杂环化合物、其组合物及其作为抗流感病毒药物的应用
EP1896403A1 (en) An improved process for the preparation of florfenicol
RU2010133139A (ru) Способ получения n-(6-метил-2,4-диоксо-1,2,3,4-тетрагидро-5-пиримидинсульфон)-n'-изоникотиноилгидразида
ITMI20120655A1 (it) Procedimento per la preparazione di linezolid