AU2009211157A1 - Novel process for the preparation of vorinostat - Google Patents

Novel process for the preparation of vorinostat Download PDF

Info

Publication number
AU2009211157A1
AU2009211157A1 AU2009211157A AU2009211157A AU2009211157A1 AU 2009211157 A1 AU2009211157 A1 AU 2009211157A1 AU 2009211157 A AU2009211157 A AU 2009211157A AU 2009211157 A AU2009211157 A AU 2009211157A AU 2009211157 A1 AU2009211157 A1 AU 2009211157A1
Authority
AU
Australia
Prior art keywords
process according
vorinostat
treating
temperature
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2009211157A
Other languages
English (en)
Inventor
Bharati Choudhari
Abhay Gaitonde
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Generics UK Ltd
Original Assignee
Generics UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Generics UK Ltd filed Critical Generics UK Ltd
Publication of AU2009211157A1 publication Critical patent/AU2009211157A1/en
Assigned to GENERICS [UK] LIMITED reassignment GENERICS [UK] LIMITED Request for Assignment Assignors: GENERICS [UK] LIMITED, MYLAN INDIA PRIVATE LIMITED
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2009211157A 2008-02-07 2009-02-06 Novel process for the preparation of vorinostat Abandoned AU2009211157A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN220KO2008 2008-02-07
IN220/KOL/2008 2008-02-07
PCT/GB2009/050117 WO2009098515A1 (en) 2008-02-07 2009-02-06 Novel process for the preparation of vorinostat

Publications (1)

Publication Number Publication Date
AU2009211157A1 true AU2009211157A1 (en) 2009-08-13

Family

ID=40637203

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009211157A Abandoned AU2009211157A1 (en) 2008-02-07 2009-02-06 Novel process for the preparation of vorinostat

Country Status (8)

Country Link
US (1) US20110039937A1 (enExample)
EP (1) EP2240436A1 (enExample)
JP (1) JP2011511053A (enExample)
CN (1) CN101939289A (enExample)
AU (1) AU2009211157A1 (enExample)
CA (1) CA2712858A1 (enExample)
NZ (1) NZ586955A (enExample)
WO (1) WO2009098515A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2349985A2 (en) * 2008-10-15 2011-08-03 Generics [UK] Limited Process for the preparation of vorinostat
EP2362869A2 (en) 2008-11-26 2011-09-07 Generics [UK] Limited Polymorphs
CN103018346A (zh) * 2011-09-20 2013-04-03 北京本草天源药物研究院 伏立诺他及其药物组合物中的杂质的高效液相色谱分析方法
CN103922967B (zh) * 2014-04-15 2016-06-01 北京化工大学 一种异羟肟酸类化合物及其在制备抑制癌细胞增殖和/或治疗癌症的药物中的应用
CN109096148B (zh) * 2018-10-16 2021-04-20 新昌县勤勉生物医药科技有限公司 利用改性介孔材料一锅法制备伏立诺他的方法
CN113943232A (zh) * 2021-11-25 2022-01-18 汤斌 一种从大鲵肽中提取伏立诺他的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5369108A (en) 1991-10-04 1994-11-29 Sloan-Kettering Institute For Cancer Research Potent inducers of terminal differentiation and methods of use thereof
US5545665A (en) * 1993-12-28 1996-08-13 Allergan Cyclopentane(ene) heptenoic or heptanoic acids and derivatives thereof useful as therapeutic agents
EP1541549A1 (en) 2003-12-12 2005-06-15 Exonhit Therapeutics S.A. Tricyclic hydroxamate and benzaminde derivatives, compositions and methods

Also Published As

Publication number Publication date
CN101939289A (zh) 2011-01-05
US20110039937A1 (en) 2011-02-17
CA2712858A1 (en) 2009-08-13
EP2240436A1 (en) 2010-10-20
WO2009098515A1 (en) 2009-08-13
NZ586955A (en) 2012-06-29
JP2011511053A (ja) 2011-04-07

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Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: GENERICS [UK] LIMITED

Free format text: FORMER APPLICANT(S): MYLAN INDIA PRIVATE LIMITED; GENERICS [UK] LIMITED

MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application