JP2011508790A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2011508790A5 JP2011508790A5 JP2010542439A JP2010542439A JP2011508790A5 JP 2011508790 A5 JP2011508790 A5 JP 2011508790A5 JP 2010542439 A JP2010542439 A JP 2010542439A JP 2010542439 A JP2010542439 A JP 2010542439A JP 2011508790 A5 JP2011508790 A5 JP 2011508790A5
- Authority
- JP
- Japan
- Prior art keywords
- medical device
- implantable medical
- bioactive agent
- powder
- clonidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012867 bioactive agent Substances 0.000 claims 15
- 239000002245 particle Substances 0.000 claims 12
- 239000000843 powder Substances 0.000 claims 12
- 229940079593 drug Drugs 0.000 claims 10
- 239000003814 drug Substances 0.000 claims 10
- GJSURZIOUXUGAL-UHFFFAOYSA-N Clonidine Chemical compound ClC1=CC=CC(Cl)=C1NC1=NCCN1 GJSURZIOUXUGAL-UHFFFAOYSA-N 0.000 claims 7
- 229960002896 clonidine Drugs 0.000 claims 7
- 239000000203 mixture Substances 0.000 claims 7
- 229920000642 polymer Polymers 0.000 claims 7
- 238000000034 method Methods 0.000 claims 5
- 238000002156 mixing Methods 0.000 claims 4
- ZNIFSRGNXRYGHF-UHFFFAOYSA-N Clonidine hydrochloride Chemical group Cl.ClC1=CC=CC(Cl)=C1NC1=NCCN1 ZNIFSRGNXRYGHF-UHFFFAOYSA-N 0.000 claims 3
- 229920001710 Polyorthoester Polymers 0.000 claims 3
- 229920002988 biodegradable polymer Polymers 0.000 claims 3
- 239000004621 biodegradable polymer Substances 0.000 claims 3
- 229960002925 clonidine hydrochloride Drugs 0.000 claims 3
- 229920000747 poly(lactic acid) Polymers 0.000 claims 3
- 239000002745 poly(ortho ester) Substances 0.000 claims 3
- 239000007788 liquid Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000012803 melt mixture Substances 0.000 claims 2
- 238000001694 spray drying Methods 0.000 claims 2
- 238000010828 elution Methods 0.000 claims 1
- 238000002513 implantation Methods 0.000 claims 1
- 230000004962 physiological condition Effects 0.000 claims 1
- 210000003497 sciatic nerve Anatomy 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4621308P | 2008-04-18 | 2008-04-18 | |
| US61/046,213 | 2008-04-18 | ||
| US12/410,151 US8557273B2 (en) | 2008-04-18 | 2009-03-24 | Medical devices and methods including polymers having biologically active agents therein |
| US12/410,151 | 2009-03-24 | ||
| PCT/US2009/040916 WO2009129439A2 (en) | 2008-04-18 | 2009-04-17 | Medical devices and methods including polymers having biologically active agents therein |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013011995A Division JP5693623B2 (ja) | 2008-04-18 | 2013-01-25 | 生物活性薬剤を含有するポリマーを含む医療用デバイスおよび方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011508790A JP2011508790A (ja) | 2011-03-17 |
| JP2011508790A5 true JP2011508790A5 (enExample) | 2011-05-12 |
| JP5197763B2 JP5197763B2 (ja) | 2013-05-15 |
Family
ID=40636913
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010542439A Active JP5197763B2 (ja) | 2008-04-18 | 2009-04-17 | 生物活性薬剤を含有するポリマーを含む医療用デバイスおよび方法 |
| JP2013011995A Active JP5693623B2 (ja) | 2008-04-18 | 2013-01-25 | 生物活性薬剤を含有するポリマーを含む医療用デバイスおよび方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013011995A Active JP5693623B2 (ja) | 2008-04-18 | 2013-01-25 | 生物活性薬剤を含有するポリマーを含む医療用デバイスおよび方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US8557273B2 (enExample) |
| EP (2) | EP2197419B1 (enExample) |
| JP (2) | JP5197763B2 (enExample) |
| KR (1) | KR20100054844A (enExample) |
| CN (2) | CN103142459B (enExample) |
| AU (1) | AU2009236094B2 (enExample) |
| BR (1) | BRPI0904961A2 (enExample) |
| CA (1) | CA2700561A1 (enExample) |
| RU (1) | RU2521395C2 (enExample) |
| WO (1) | WO2009129439A2 (enExample) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007011708A2 (en) | 2005-07-15 | 2007-01-25 | Micell Technologies, Inc. | Stent with polymer coating containing amorphous rapamycin |
| JP5756588B2 (ja) | 2005-07-15 | 2015-07-29 | ミセル テクノロジーズ、インコーポレイテッド | 制御されたモルホロジーの薬剤粉末を含むポリマーコーティング |
| CA2996768C (en) | 2006-04-26 | 2020-12-08 | Micell Technologies, Inc. | Coatings containing multiple drugs |
| EP2081694B1 (en) | 2006-10-23 | 2020-05-13 | Micell Technologies, Inc. | Holder for electrically charging a substrate during coating |
| US11426494B2 (en) | 2007-01-08 | 2022-08-30 | MT Acquisition Holdings LLC | Stents having biodegradable layers |
| JP5603598B2 (ja) | 2007-01-08 | 2014-10-08 | ミセル テクノロジーズ、インコーポレイテッド | 生物分解層を有するステント |
| US9433516B2 (en) | 2007-04-17 | 2016-09-06 | Micell Technologies, Inc. | Stents having controlled elution |
| AU2008256684B2 (en) | 2007-05-25 | 2012-06-14 | Micell Technologies, Inc. | Polymer films for medical device coating |
| BRPI0910969B8 (pt) | 2008-04-17 | 2021-06-22 | Micell Technologies Inc | dispositivo |
| USRE48948E1 (en) | 2008-04-18 | 2022-03-01 | Warsaw Orthopedic, Inc. | Clonidine compounds in a biodegradable polymer |
| US8557273B2 (en) * | 2008-04-18 | 2013-10-15 | Medtronic, Inc. | Medical devices and methods including polymers having biologically active agents therein |
| EP2313122B1 (en) | 2008-07-17 | 2019-03-06 | Micell Technologies, Inc. | Drug delivery medical device |
| WO2011009096A1 (en) | 2009-07-16 | 2011-01-20 | Micell Technologies, Inc. | Drug delivery medical device |
| US8834913B2 (en) | 2008-12-26 | 2014-09-16 | Battelle Memorial Institute | Medical implants and methods of making medical implants |
| US20110189761A1 (en) * | 2009-01-26 | 2011-08-04 | Island Giant Development Llp | Method for producing cell culture scaffold |
| US20100239632A1 (en) | 2009-03-23 | 2010-09-23 | Warsaw Orthopedic, Inc. | Drug depots for treatment of pain and inflammation in sinus and nasal cavities or cardiac tissue |
| EP2413847A4 (en) | 2009-04-01 | 2013-11-27 | Micell Technologies Inc | COATED STENTS |
| EP2531140B1 (en) | 2010-02-02 | 2017-11-01 | Micell Technologies, Inc. | Stent and stent delivery system with improved deliverability |
| US9554830B2 (en) | 2010-02-25 | 2017-01-31 | Mayo Foundation For Medical Education And Research | Delivering drugs to desired locations within a mammal |
| US8795762B2 (en) | 2010-03-26 | 2014-08-05 | Battelle Memorial Institute | System and method for enhanced electrostatic deposition and surface coatings |
| EP2558101A4 (en) * | 2010-04-15 | 2013-09-18 | Univ Mcgill | TOPICAL TREATMENTS OF PAIN |
| WO2011133655A1 (en) | 2010-04-22 | 2011-10-27 | Micell Technologies, Inc. | Stents and other devices having extracellular matrix coating |
| WO2011133370A1 (en) * | 2010-04-23 | 2011-10-27 | Medtronic, Inc. | Shelf stable pharmaceutical depot |
| US8747883B2 (en) * | 2010-06-02 | 2014-06-10 | Princeton Trade & Technology, Inc. | Medical item for long term drug release |
| US11033624B2 (en) | 2010-06-02 | 2021-06-15 | Novaflux Inc. | Medical item for prevention and treatment of ear infection |
| EP2593039B1 (en) | 2010-07-16 | 2022-11-30 | Micell Technologies, Inc. | Drug delivery medical device |
| CA2810842C (en) | 2010-09-09 | 2018-06-26 | Micell Technologies, Inc. | Macrolide dosage forms |
| WO2012075440A2 (en) * | 2010-12-03 | 2012-06-07 | Warsaw Orthopedic, Inc. | Compositions and methods for delivering clonidine to a target tissue site |
| US9005634B2 (en) | 2011-04-13 | 2015-04-14 | Medtronic, Inc. | Shelf stable pharmaceutical depot |
| WO2012166819A1 (en) | 2011-05-31 | 2012-12-06 | Micell Technologies, Inc. | System and process for formation of a time-released, drug-eluting transferable coating |
| WO2012166934A1 (en) * | 2011-06-01 | 2012-12-06 | The Regents Of The University Of California | Methods and compositions for the treatment of pain |
| CN103889434B (zh) | 2011-06-21 | 2017-02-15 | Bvw控股公司 | 含有乳香酸的医疗装置 |
| WO2013012689A1 (en) | 2011-07-15 | 2013-01-24 | Micell Technologies, Inc. | Drug delivery medical device |
| US10188772B2 (en) | 2011-10-18 | 2019-01-29 | Micell Technologies, Inc. | Drug delivery medical device |
| HK1205953A1 (en) | 2012-03-20 | 2015-12-31 | Trustees Of Tufts College | Silk reservoirs for drug delivery |
| US9511018B2 (en) * | 2012-04-05 | 2016-12-06 | Warsaw Orthopedic, Inc. | Clonidine compounds in a biodegradable matrix |
| JP6330024B2 (ja) | 2013-03-12 | 2018-05-23 | マイセル・テクノロジーズ,インコーポレイテッド | 生体吸収性バイオメディカルインプラント |
| ITTO20130284A1 (it) * | 2013-04-09 | 2014-10-10 | Fond Istituto Italiano Di Tecnologia | Procedimento per la produzione di microparticelle polimeriche sagomate |
| JP2016519965A (ja) | 2013-05-15 | 2016-07-11 | マイセル・テクノロジーズ,インコーポレイテッド | 生体吸収性バイオメディカルインプラント |
| US10099035B2 (en) * | 2014-04-22 | 2018-10-16 | Medtronic Ardian Luxembourg S.A.R.L. | Anti-resterilization components for catheter treatment devices and associated devices, systems, and methods |
| US10285865B2 (en) | 2014-05-02 | 2019-05-14 | Novaflux Inc. | Drug-releasing device usable in mucosal body cavities |
| US10080877B2 (en) | 2014-07-25 | 2018-09-25 | Warsaw Orthopedic, Inc. | Drug delivery device and methods having a drug cartridge |
| US9775978B2 (en) | 2014-07-25 | 2017-10-03 | Warsaw Orthopedic, Inc. | Drug delivery device and methods having a retaining member |
| CN105560161B (zh) * | 2014-10-09 | 2019-11-12 | 安徽中人科技有限责任公司 | 一种肾用地塞米松植入剂制备方法 |
| CN104667346B (zh) * | 2015-03-21 | 2016-09-14 | 杨青芳 | 一种可生物降解纳米微球的制备方法和应用 |
| GB201505527D0 (en) | 2015-03-31 | 2015-05-13 | Jmedtech Pte Ltd | Composition |
| US20170065521A1 (en) * | 2015-09-09 | 2017-03-09 | Micell Technologies, Inc. | Biopharma application of micell technology |
| TWI799366B (zh) | 2015-09-15 | 2023-04-21 | 美商建南德克公司 | 胱胺酸結骨架平臺 |
| US10076650B2 (en) | 2015-11-23 | 2018-09-18 | Warsaw Orthopedic, Inc. | Enhanced stylet for drug depot injector |
| USD802757S1 (en) | 2016-06-23 | 2017-11-14 | Warsaw Orthopedic, Inc. | Drug pellet cartridge |
| US10913930B2 (en) | 2016-08-09 | 2021-02-09 | Warsaw Orthopedic, Inc. | Tissue processing apparatus and method for infusing bioactive agents into tissue |
| US10898447B2 (en) | 2016-10-27 | 2021-01-26 | Psirrros Inc. | Finished pharmaceutical form with individual medicine dosing capability (embodiments) and methods of its production and use |
| US10434261B2 (en) | 2016-11-08 | 2019-10-08 | Warsaw Orthopedic, Inc. | Drug pellet delivery system and method |
| EP3570833A4 (en) | 2017-01-20 | 2020-08-05 | Warsaw Orthopedic, Inc. | ANESTHETIC COMPOSITIONS AND PROCEDURES USING IMIDAZOLINE COMPOUNDS |
| RU2671203C2 (ru) * | 2017-01-30 | 2018-10-30 | Общество с ограниченной ответственностью "Омские медицинские технологии" (ООО "ОММЕДТЕХ") | Способ остеосинтеза переломов трубчатых костей |
| WO2019071246A2 (en) | 2017-10-06 | 2019-04-11 | Foundry Therapeutics, Inc. | IMPLANTABLE DEPOSITS FOR CONTROLLED RELEASE OF ANALGESICS TO TREAT POSTOPERATIVE PAIN, AND DEVICES, SYSTEMS, AND RELATED METHODS |
| US12364792B2 (en) | 2018-01-08 | 2025-07-22 | Foundry Therapeutics, Inc. | Devices, systems, and methods for treating intraluminal cancer via controlled delivery of therapeutic agents |
| CN108814667B (zh) * | 2018-02-12 | 2020-12-11 | 东莞市奥慧捷医疗器械有限公司 | 一种皮下缝合钉及其制备方法 |
| CN108814766B (zh) * | 2018-03-15 | 2020-12-11 | 东莞市奥慧捷医疗器械有限公司 | 一种疝气补片固定钉及其制备方法 |
| WO2019221853A1 (en) | 2018-05-12 | 2019-11-21 | Foundry Therapeutics, Inc. | Implantable depots for the controlled release of therapeutic agents |
| WO2020047013A1 (en) | 2018-08-28 | 2020-03-05 | Foundry Therapeutics, Inc. | Polymer implants |
| RU2721880C1 (ru) * | 2019-07-09 | 2020-05-25 | Федеральное государственное бюджетное учреждение науки Федеральный исследовательский центр химической физики им. Н.Н. Семенова Российской академии наук (ФИЦ ХФ РАН) | Способ повышения регенерационного потенциала имплантируемого материала для восстановительной хирургии (варианты) |
| US12403291B2 (en) | 2019-08-30 | 2025-09-02 | Intersect Ent, Inc. | Submucosal bioresorbable drug eluting platform |
Family Cites Families (77)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3020660A (en) | 1959-11-30 | 1962-02-13 | Scherotto John | Collapsible imitation tree |
| US3190802A (en) | 1961-10-09 | 1965-06-22 | Boehringer Sohn Ingelheim | Shaving composition and method of using same |
| US4231938A (en) | 1979-06-15 | 1980-11-04 | Merck & Co., Inc. | Hypocholesteremic fermentation products and process of preparation |
| US4621308A (en) | 1984-01-16 | 1986-11-04 | Rodney D. Holmberg | Tackle box with light unit assembly |
| US4765974A (en) | 1985-12-24 | 1988-08-23 | Nitto Electric Industrial Co., Ltd. | Preparation for percutaneous administration |
| US5175052A (en) | 1988-05-11 | 1992-12-29 | Nitto Denko Corporation | Adhesive tape preparation of clonidine |
| US5077049A (en) * | 1989-07-24 | 1991-12-31 | Vipont Pharmaceutical, Inc. | Biodegradable system for regenerating the periodontium |
| US5447947A (en) | 1990-02-26 | 1995-09-05 | Arc 1 | Compositions and methods of treatment of sympathetically maintained pain |
| US5484607A (en) | 1993-10-13 | 1996-01-16 | Horacek; H. Joseph | Extended release clonidine formulation |
| US5635204A (en) | 1994-03-04 | 1997-06-03 | Montefiore Medical Center | Method for transdermal induction of anesthesia, analgesia or sedation |
| DE69603577T2 (de) * | 1995-02-10 | 1999-11-25 | Medtronic, Inc. | Verfahren und vorrichtung zur verabreichung von analgetika |
| DE19542281C2 (de) | 1995-11-14 | 1997-12-04 | Boehringer Ingelheim Kg | Verwendung von Epinastin für die Behandlung der Migräne |
| CN1494907A (zh) | 1996-03-25 | 2004-05-12 | 治疗疼痛的药物组合物 | |
| US6495579B1 (en) * | 1996-12-02 | 2002-12-17 | Angiotech Pharmaceuticals, Inc. | Method for treating multiple sclerosis |
| WO1998027963A2 (en) * | 1996-12-20 | 1998-07-02 | Alza Corporation | Gel composition and methods |
| US5801188A (en) | 1997-01-08 | 1998-09-01 | Medtronic Inc. | Clonidine therapy enhancement |
| US6294170B1 (en) | 1997-08-08 | 2001-09-25 | Amgen Inc. | Composition and method for treating inflammatory diseases |
| US5942530A (en) | 1997-08-28 | 1999-08-24 | Eli Lilly And Company | Method for treating pain |
| TW577758B (en) | 1997-10-27 | 2004-03-01 | Ssp Co Ltd | Intra-articular preparation for the treatment of arthropathy |
| US6069129A (en) | 1998-03-13 | 2000-05-30 | Mrs, Llc | Elastin derived composition and method of using same |
| US6632457B1 (en) | 1998-08-14 | 2003-10-14 | Incept Llc | Composite hydrogel drug delivery systems |
| US6179862B1 (en) | 1998-08-14 | 2001-01-30 | Incept Llc | Methods and apparatus for in situ formation of hydrogels |
| US6927044B2 (en) | 1998-09-25 | 2005-08-09 | Regeneron Pharmaceuticals, Inc. | IL-1 receptor based cytokine traps |
| US6143314A (en) | 1998-10-28 | 2000-11-07 | Atrix Laboratories, Inc. | Controlled release liquid delivery compositions with low initial drug burst |
| US6565874B1 (en) | 1998-10-28 | 2003-05-20 | Atrix Laboratories | Polymeric delivery formulations of leuprolide with improved efficacy |
| US6287588B1 (en) | 1999-04-29 | 2001-09-11 | Macromed, Inc. | Agent delivering system comprised of microparticle and biodegradable gel with an improved releasing profile and methods of use thereof |
| US6147102A (en) | 1999-10-26 | 2000-11-14 | Curatek Pharmaceuticals Holding, Inc. | Clonidine preparations |
| US6461631B1 (en) | 1999-11-16 | 2002-10-08 | Atrix Laboratories, Inc. | Biodegradable polymer composition |
| EP1103260B1 (de) | 1999-11-29 | 2005-01-26 | Novosis AG | Transdermalsystem zur Abgabe von Clonidin |
| US6287688B1 (en) | 2000-03-03 | 2001-09-11 | E. I. Du Pont De Nemours And Company | Partially oriented poly(trimethylene terephthalate) yarn |
| US6589549B2 (en) | 2000-04-27 | 2003-07-08 | Macromed, Incorporated | Bioactive agent delivering system comprised of microparticles within a biodegradable to improve release profiles |
| WO2002000137A1 (en) * | 2000-06-28 | 2002-01-03 | Shukla Atul J | Biodegradable vehicles and delivery systems of biologically active substances |
| US6417184B1 (en) | 2000-09-19 | 2002-07-09 | David M. Ockert | Triple drug therapy for the treatment and prevention of acute or chronic pain |
| AU2002248284A1 (en) | 2000-11-01 | 2002-08-06 | Allergan, Inc. | Compositions for treatment of ocular neovascularization |
| US20030022926A1 (en) | 2001-05-07 | 2003-01-30 | Lavand'homme Patricia | Method for treating neuropathic pain and pharmaceutical preparation therefor |
| US6737042B2 (en) | 2001-05-24 | 2004-05-18 | Alexza Molecular Delivery Corporation | Delivery of drug esters through an inhalation route |
| US6602911B2 (en) | 2001-11-05 | 2003-08-05 | Cypress Bioscience, Inc. | Methods of treating fibromyalgia |
| MXPA01011542A (es) | 2001-11-13 | 2003-05-22 | Alcon Inc | Regeneracion del cartilago articular da°ado por la osteoartritis de grado i y ii, mediante la aplicacion intra-articular de una mezcla de hialuronato de sodio y de condroitin sulfato en un vehiculo de gel. |
| KR20040058100A (ko) * | 2001-11-14 | 2004-07-03 | 알자 코포레이션 | 주입가능한 데포 조성물 및 그의 용도 |
| US7345065B2 (en) | 2002-05-21 | 2008-03-18 | Allergan, Inc. | Methods and compositions for alleviating pain |
| CA2490007C (en) | 2002-07-19 | 2011-05-24 | Omeros Corporation | Biodegradable triblock copolymers, synthesis methods therefor, and hydrogels and biomaterials made there from |
| US7687080B2 (en) | 2002-11-25 | 2010-03-30 | Taraxos Inc. | Treatment of neuropathy |
| US20050048099A1 (en) | 2003-01-09 | 2005-03-03 | Allergan, Inc. | Ocular implant made by a double extrusion process |
| US20040166088A1 (en) | 2003-01-15 | 2004-08-26 | Shalaby Shalaby W. | Polymeric precursors of non-absorbable, in situ-forming hydrogels and applications thereof |
| US20040208917A1 (en) | 2003-04-16 | 2004-10-21 | Wilfried Fischer | Transdermal systems for the release of clonidine |
| KR20060023140A (ko) * | 2003-05-30 | 2006-03-13 | 알자 코포레이션 | 이식성 탄성중합체 데포 조성물, 이의 용도 및 이의제조방법 |
| US20040265364A1 (en) | 2003-06-25 | 2004-12-30 | Binnur Ozturk | Neuropathy cream |
| US20050095277A1 (en) | 2003-06-25 | 2005-05-05 | Binnur Ozturk | Neuropathy cream |
| US20050059744A1 (en) | 2003-09-12 | 2005-03-17 | Allergan, Inc. | Methods and compositions for the treatment of pain and other alpha 2 adrenergic-mediated conditions |
| US20050058696A1 (en) | 2003-09-12 | 2005-03-17 | Allergan, Inc. | Methods and compositions for the treatment of pain and other alpha 2 adrenergic-mediated conditions |
| JP2007507538A (ja) | 2003-10-02 | 2007-03-29 | エラン ファーマシューティカルズ,インコーポレイテッド | 疼痛軽減方法 |
| WO2005046746A2 (en) | 2003-11-10 | 2005-05-26 | Angiotech International Ag | Medical implants and fibrosis-inducing agents |
| JP2007519756A (ja) | 2004-01-30 | 2007-07-19 | アンジオテック インターナショナル アーゲー | 拘縮を治療するための組成物および方法 |
| US7232435B2 (en) * | 2004-02-06 | 2007-06-19 | Medtronic, Inc. | Delivery of a sympatholytic cardiovascular agent to the central nervous system to counter heart failure and pathologies associated with heart failure |
| US8685435B2 (en) * | 2004-04-30 | 2014-04-01 | Allergan, Inc. | Extended release biodegradable ocular implants |
| US7589057B2 (en) | 2004-04-30 | 2009-09-15 | Allergan, Inc. | Oil-in-water method for making alpha-2 agonist polymeric drug delivery systems |
| WO2006022611A2 (en) | 2004-06-26 | 2006-03-02 | Binnur Ozturk | Neuropathy cream |
| US7294138B2 (en) | 2004-06-28 | 2007-11-13 | Shippert Ronald D | Nose pack method and apparatus |
| US20060253100A1 (en) | 2004-10-22 | 2006-11-09 | Medtronic, Inc. | Systems and Methods to Treat Pain Locally |
| EA200701131A1 (ru) | 2004-11-24 | 2007-12-28 | Алгоркс Фармасьютикалз, Инк. | Гелеобразная препаративная форма капсаициноида и способы её применения |
| US7611494B2 (en) | 2005-02-08 | 2009-11-03 | Confluent Surgical, Inc. | Spray for fluent materials |
| US20060204548A1 (en) * | 2005-03-01 | 2006-09-14 | Allergan, Inc. | Microimplants for ocular administration |
| US20060211665A1 (en) | 2005-03-17 | 2006-09-21 | Ranawat Chitranjan S | Reduction of postoperative pain medication |
| EP1888049A2 (en) | 2005-05-25 | 2008-02-20 | The Massachusetts Institute Of Technology | Localized delivery of cardiac inotropic agents |
| US9259267B2 (en) | 2005-09-06 | 2016-02-16 | W.L. Gore & Associates, Inc. | Devices and methods for treating cardiac tissue |
| US20070104769A1 (en) | 2005-11-04 | 2007-05-10 | Lifescience Plus, Inc. | Bioabsorbable hemostatic gauze |
| US10029034B2 (en) * | 2005-12-15 | 2018-07-24 | CARDINAL HEALTH SWITZERLAND 515 GmbH | Drug-eluting articles with improved drug release profiles |
| US7610100B2 (en) | 2005-12-30 | 2009-10-27 | Boston Scientific Neuromodulation Corporation | Methods and systems for treating osteoarthritis |
| US7741273B2 (en) | 2006-04-13 | 2010-06-22 | Warsaw Orthopedic, Inc. | Drug depot implant designs |
| US8974542B2 (en) | 2006-06-27 | 2015-03-10 | University of Pittsburgh—of the Commonwealth System of Higher Education | Biodegradable elastomeric patch for treating cardiac or cardiovascular conditions |
| US20080075777A1 (en) * | 2006-07-31 | 2008-03-27 | Kennedy Michael T | Apparatus and methods for preparing solid particles |
| US20080095831A1 (en) * | 2006-08-10 | 2008-04-24 | Mc Graw Thomas L | Topical formulation of multilamellar vesicles composition for percutaneous absorption of pharmaceutically active agent |
| US7671014B2 (en) | 2006-08-14 | 2010-03-02 | Warsaw Orthopedic, Inc. | Flowable carrier matrix and methods for delivering to a patient |
| US20080091207A1 (en) | 2006-10-13 | 2008-04-17 | Csaba Truckai | Bone treatment systems and methods |
| US20080152709A1 (en) | 2006-12-22 | 2008-06-26 | Drugtech Corporation | Clonidine composition and method of use |
| WO2009100441A2 (en) | 2008-02-08 | 2009-08-13 | Impax Laboratories, Inc. | Depot formulations |
| US8557273B2 (en) * | 2008-04-18 | 2013-10-15 | Medtronic, Inc. | Medical devices and methods including polymers having biologically active agents therein |
-
2009
- 2009-03-24 US US12/410,151 patent/US8557273B2/en active Active
- 2009-04-17 CN CN201310040836.XA patent/CN103142459B/zh active Active
- 2009-04-17 AU AU2009236094A patent/AU2009236094B2/en active Active
- 2009-04-17 CA CA2700561A patent/CA2700561A1/en not_active Abandoned
- 2009-04-17 EP EP09732647.4A patent/EP2197419B1/en active Active
- 2009-04-17 KR KR1020107006576A patent/KR20100054844A/ko not_active Ceased
- 2009-04-17 RU RU2010111356/15A patent/RU2521395C2/ru active IP Right Revival
- 2009-04-17 JP JP2010542439A patent/JP5197763B2/ja active Active
- 2009-04-17 BR BRPI0904961-4A patent/BRPI0904961A2/pt not_active IP Right Cessation
- 2009-04-17 WO PCT/US2009/040916 patent/WO2009129439A2/en not_active Ceased
- 2009-04-17 CN CN2009801005423A patent/CN101808620B/zh active Active
- 2009-04-17 EP EP19209012.4A patent/EP3666255A1/en not_active Withdrawn
-
2013
- 2013-01-25 JP JP2013011995A patent/JP5693623B2/ja active Active
- 2013-07-03 US US13/934,375 patent/US8999368B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2011508790A5 (enExample) | ||
| WO2009129439A4 (en) | Medical devices and methods including polymers having biologically active agents therein | |
| JP5923493B2 (ja) | 注射可能なデポー組成物の調製方法 | |
| JP5882993B2 (ja) | 抗精神病薬デポ型注射用組成物 | |
| KR101194894B1 (ko) | 클로니딘을 포함하는 수술-후 통증 치료용 조성물 | |
| AU2006299657B2 (en) | Sustained release small molecule drug formulation | |
| US20160038655A1 (en) | Methods and Devices For Three-Dimensional Printing Or Additive Manufacturing Of Bioactive Medical Devices | |
| JP2013527213A5 (enExample) | ||
| JP2012525374A (ja) | GnRH類似体含有徐放配合物 | |
| US20200030491A1 (en) | Methods and Devices For Three-Dimensional Printing Or Additive Manufacturing Of Bioactive Medical Devices | |
| HRP20140158T1 (hr) | Formulacija paliperidon implantata | |
| CN101522170A (zh) | 在延长的一段时间里释放活性成分的皮下植入剂 | |
| AU2009236419A1 (en) | Dexamethasone formulations in a biodegradable material | |
| EP2403482A1 (en) | Abuse resistant formulation | |
| US10188602B2 (en) | Bioerodible implant for long-term drug delivery and associated methods of manufacture and use | |
| WO2009129510A2 (en) | Sulindac formulations in a biodegradable material | |
| JP2011508791A (ja) | 生物分解性ポリマー担体中のフルオシノロン製剤 | |
| HRP20220922T1 (hr) | Usadive tablete naltreksona | |
| AU2010305430B2 (en) | Delivery system for sustained release of a calcium -channel blocking agent | |
| CN101677946A (zh) | 具有改善的掩味的挤出物 | |
| CN1316954C (zh) | 一种植入式局部给药装置及其三维打印制备方法 | |
| DE3807523A1 (de) | Oral verabreichbares system zur kontrollierten freigabe von wirkstoffen | |
| US20230080240A1 (en) | Drug implants containing enzalutamide and methods of use thereof | |
| CN102166371B (zh) | 药物可控时序释放的含多种药物的磷酸钙骨水泥粉末 | |
| CN101553212A (zh) | 在延长的一段时间里释放活性成分的皮下植入剂 |