JP2011507920A5 - - Google Patents
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- Publication number
- JP2011507920A5 JP2011507920A5 JP2010540059A JP2010540059A JP2011507920A5 JP 2011507920 A5 JP2011507920 A5 JP 2011507920A5 JP 2010540059 A JP2010540059 A JP 2010540059A JP 2010540059 A JP2010540059 A JP 2010540059A JP 2011507920 A5 JP2011507920 A5 JP 2011507920A5
- Authority
- JP
- Japan
- Prior art keywords
- gel
- epo
- formulation
- polysaccharide
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000003951 Erythropoietin Human genes 0.000 claims 13
- 108090000394 Erythropoietin Proteins 0.000 claims 13
- 229940105423 erythropoietin Drugs 0.000 claims 13
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 claims 13
- 238000009472 formulation Methods 0.000 claims 10
- 239000000203 mixture Substances 0.000 claims 10
- 150000004676 glycans Chemical class 0.000 claims 6
- 229920001282 polysaccharide Polymers 0.000 claims 6
- 239000005017 polysaccharide Substances 0.000 claims 6
- 206010052428 Wound Diseases 0.000 claims 5
- 208000027418 Wounds and injury Diseases 0.000 claims 5
- 238000000034 method Methods 0.000 claims 4
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 3
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 3
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims 3
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims 3
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims 2
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims 2
- 229920003064 carboxyethyl cellulose Polymers 0.000 claims 2
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims 2
- 229920003063 hydroxymethyl cellulose Polymers 0.000 claims 2
- 229940031574 hydroxymethyl cellulose Drugs 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000011159 matrix material Substances 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 230000008961 swelling Effects 0.000 claims 2
- 230000000472 traumatic effect Effects 0.000 claims 2
- 230000004071 biological effect Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 230000001684 chronic effect Effects 0.000 claims 1
- 238000009792 diffusion process Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000000302 ischemic effect Effects 0.000 claims 1
- 239000011505 plaster Substances 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07025167.3 | 2007-12-28 | ||
| EP07025167 | 2007-12-28 | ||
| PCT/EP2008/010978 WO2009083203A2 (de) | 2007-12-28 | 2008-12-20 | Topische anwendung und formulierung von erythropoietin für die wundheilung der haut |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011507920A JP2011507920A (ja) | 2011-03-10 |
| JP2011507920A5 true JP2011507920A5 (https=) | 2011-05-06 |
| JP5553769B2 JP5553769B2 (ja) | 2014-07-16 |
Family
ID=40751089
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010540059A Active JP5553769B2 (ja) | 2007-12-28 | 2008-12-20 | 皮膚創傷治癒のためのエリスロポエチンの局所適用および製剤 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9101586B2 (https=) |
| EP (1) | EP2222327B1 (https=) |
| JP (1) | JP5553769B2 (https=) |
| CN (1) | CN101951944B (https=) |
| AU (1) | AU2008342920B2 (https=) |
| BR (1) | BRPI0821814A2 (https=) |
| CA (1) | CA2709545C (https=) |
| DK (1) | DK2222327T3 (https=) |
| ES (1) | ES2625145T3 (https=) |
| RU (1) | RU2465003C2 (https=) |
| WO (1) | WO2009083203A2 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5869219B2 (ja) | 2007-08-16 | 2016-02-24 | レメドー バイオメッド リミテッド | 治療および美容適用のためのエリスロポイエチンおよびフィブロネクチン組成物 |
| EP2590666B1 (en) | 2010-07-06 | 2017-04-26 | Augustinus Bader | Topical application of erythropoietin for use in the treatment of injuries of the cornea |
| WO2012031778A1 (de) | 2010-09-12 | 2012-03-15 | Augustinus Bader | Verwendung von erythropoietin bei der heilung von wunden oder gewebedefekten ohne narbenbildung |
| EP2919805B1 (en) * | 2012-11-14 | 2022-01-05 | Smith & Nephew, Inc. | Stable thermolysin hydrogel |
| AU2014235578B2 (en) | 2013-03-15 | 2017-08-17 | Smith & Nephew, Inc. | Dissolvable gel-forming film for delivery of active agents |
| CA2909956C (en) * | 2013-04-30 | 2021-06-01 | University Of Southern California | Accelerated healing of eye injuries by angiotensin peptides |
| WO2015075406A1 (en) * | 2013-11-19 | 2015-05-28 | Lipopeptide Ab | New treatment of chronic ulcers |
| AU2016314611C1 (en) * | 2015-09-04 | 2019-12-19 | Remedor Biomed Ltd. | Topical erythropoietin formulations and methods for improving wound healing with and cosmetic use of the formulations |
| RU2611401C1 (ru) * | 2015-10-28 | 2017-02-21 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Южно-Уральский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ГБОУ ВПО ЮУГМУ Минздрава России) | Способ получения лекарственного средства с эритропоэтином местного действия |
| WO2017104725A1 (ja) * | 2015-12-16 | 2017-06-22 | 第一三共株式会社 | 創傷治療剤 |
| ES2952448T3 (es) | 2016-11-10 | 2023-10-31 | Asc Regenity Ltd | Formulaciones cosméticas para aplicaciones tópicas que contienen moléculas derivadas de eritropoyetina |
| RU2679446C2 (ru) * | 2017-03-16 | 2019-02-11 | Алексей Валерьевич Люндуп | Способ лечения синдрома диабетической стопы |
| GB201720320D0 (en) | 2017-12-06 | 2018-01-17 | Univ Of Sussex | Tissue repair |
| RU2754383C1 (ru) * | 2020-12-07 | 2021-09-01 | Федеральное Государственное Бюджетное Учреждение "Национальный Медицинский Исследовательский Центр Эндокринологии" Министерства Здравоохранения Российской Федерации (Фгбу "Нмиц Эндокринологии" Минздрава России) | Способ лечения неинфицированного послеоперационного раневого дефекта стопы при отсутствии признаков критической ишемии конечности у больных с нейропатической и нейроишемической формой синдрома диабетической стопы |
| CN112961821B (zh) * | 2021-02-24 | 2023-05-30 | 四川大学华西医院 | 三维培养血管内皮细胞的方法 |
| CN115177782B (zh) * | 2021-04-02 | 2023-07-18 | 诺一迈尔(山东)医学科技有限公司 | 一种高透气、促愈合的液体创可贴及其制备方法 |
| EP4395797A4 (en) | 2022-06-29 | 2025-09-03 | Biostem Tech Inc | MICRONIZED WOUND HEALING COMPOSITIONS PREPARED FROM INTACT HUMAN AMNION-CHORION TISSUES HAVING AN INTACT INTERMEDIATE SPONGE LAYER POSITIONED BETWEEN THEM |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2181691T5 (es) | 1992-06-11 | 2007-10-01 | Alkermes Controlled Therapeutics, Inc. | Sistema de distribucion de proteina eritropoyetina. |
| EP0850051A2 (en) | 1995-08-31 | 1998-07-01 | Alkermes Controlled Therapeutics, Inc. | Composition for sustained release of an agent |
| JP2000095678A (ja) * | 1998-09-22 | 2000-04-04 | Dai Ichi Kogyo Seiyaku Co Ltd | パップ剤用基剤およびそれを含有するパップ剤 |
| US6372494B1 (en) * | 1999-05-14 | 2002-04-16 | Advanced Tissue Sciences, Inc. | Methods of making conditioned cell culture medium compositions |
| US6818613B2 (en) * | 2001-11-07 | 2004-11-16 | Ortho-Mcneil Pharmaceutical, Inc. | Aqueous sustained-release formulations of proteins |
| JP5144876B2 (ja) * | 2002-06-20 | 2013-02-13 | バーダー、アウグスティヌス | 増殖因子を用いて、および生物学的マトリクスあるいは支持構造を用いて細胞を増殖および分化する方法およびデバイス |
| DE10260873A1 (de) * | 2002-12-23 | 2004-07-15 | Beiersdorf Ag | Selbstklebende Polymermatrix mit einem Gehalt an Meeresalgenextrakt und Glycerin |
| EP1548031A1 (en) * | 2003-12-22 | 2005-06-29 | Dubai Genetics FZ-LLC | Nature-identical erythropoietin |
| AU2004309083B2 (en) * | 2003-12-30 | 2010-11-11 | Augustinus Bader | Tissue regeneration method |
| DE10361813A1 (de) * | 2003-12-30 | 2005-09-08 | Bionethos Holding Gmbh | Verfahren zur Regeneration von Gewebe |
| WO2005070451A1 (en) | 2004-01-22 | 2005-08-04 | Zafena Aktiebolag | Pharmaceutical composition comprising non-glycosylated erythropoietin |
| CA2582255A1 (en) * | 2004-08-30 | 2006-08-08 | Lunamed, Inc. | 4-phenylbutyric acid controlled-release formulations for therapeutic use |
| JP2008530230A (ja) * | 2005-02-16 | 2008-08-07 | アルザ・コーポレーシヨン | エリスロポエチンに基づく剤の経皮送達のための装置および方法 |
| US20080247987A1 (en) * | 2005-08-04 | 2008-10-09 | Angiotech International Ag | Block Copolymer Compositions and Uses Thereof |
-
2008
- 2008-12-20 US US12/810,711 patent/US9101586B2/en active Active
- 2008-12-20 WO PCT/EP2008/010978 patent/WO2009083203A2/de not_active Ceased
- 2008-12-20 EP EP08866728.2A patent/EP2222327B1/de active Active
- 2008-12-20 DK DK08866728.2T patent/DK2222327T3/en active
- 2008-12-20 ES ES08866728.2T patent/ES2625145T3/es active Active
- 2008-12-20 AU AU2008342920A patent/AU2008342920B2/en active Active
- 2008-12-20 BR BRPI0821814-5A patent/BRPI0821814A2/pt not_active IP Right Cessation
- 2008-12-20 CA CA2709545A patent/CA2709545C/en active Active
- 2008-12-20 RU RU2010130890/15A patent/RU2465003C2/ru active IP Right Revival
- 2008-12-20 JP JP2010540059A patent/JP5553769B2/ja active Active
- 2008-12-20 CN CN200880123283.1A patent/CN101951944B/zh active Active
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