JP2011504936A5 - - Google Patents

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Publication number
JP2011504936A5
JP2011504936A5 JP2010536190A JP2010536190A JP2011504936A5 JP 2011504936 A5 JP2011504936 A5 JP 2011504936A5 JP 2010536190 A JP2010536190 A JP 2010536190A JP 2010536190 A JP2010536190 A JP 2010536190A JP 2011504936 A5 JP2011504936 A5 JP 2011504936A5
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JP
Japan
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alkyl
aralkyl
heteroaryl
cycloalkyl
group
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JP2010536190A
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English (en)
Japanese (ja)
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JP5745855B2 (ja
JP2011504936A (ja
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Priority claimed from PCT/US2008/084992 external-priority patent/WO2009070744A1/en
Publication of JP2011504936A publication Critical patent/JP2011504936A/ja
Publication of JP2011504936A5 publication Critical patent/JP2011504936A5/ja
Application granted granted Critical
Publication of JP5745855B2 publication Critical patent/JP5745855B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2010536190A 2007-11-28 2008-11-26 シトクロムｐ４５０ ２ｄ６を阻害するための組成物および方法 Expired - Fee Related JP5745855B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US99086807P 2007-11-28 2007-11-28
US60/990,868 2007-11-28
PCT/US2008/084992 WO2009070744A1 (en) 2007-11-28 2008-11-26 Compositions and methods for inhibiting cytochrome p450 2d6

Publications (3)

Publication Number Publication Date
JP2011504936A JP2011504936A (ja) 2011-02-17
JP2011504936A5 true JP2011504936A5 (cg-RX-API-DMAC7.html) 2014-01-09
JP5745855B2 JP5745855B2 (ja) 2015-07-08

Family

ID=40676387

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010536190A Expired - Fee Related JP5745855B2 (ja) 2007-11-28 2008-11-26 シトクロムｐ４５０ ２ｄ６を阻害するための組成物および方法

Country Status (8)

Country Link
US (3) US8569364B2 (cg-RX-API-DMAC7.html)
EP (1) EP2224923A4 (cg-RX-API-DMAC7.html)
JP (1) JP5745855B2 (cg-RX-API-DMAC7.html)
CN (1) CN101965186A (cg-RX-API-DMAC7.html)
AU (1) AU2008329677B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0819883A2 (cg-RX-API-DMAC7.html)
CA (1) CA2707161C (cg-RX-API-DMAC7.html)
WO (1) WO2009070744A1 (cg-RX-API-DMAC7.html)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8569364B2 (en) * 2007-11-28 2013-10-29 Sequoia Pharmaceuticals, Inc. 5-substituted benzofurans as inhibitors of cytochrome P450 2D6
BR112012028153A2 (pt) 2010-05-03 2018-08-07 Tsh Biopharm Corporation Ltd composição farmacêutica e método para o tratamento de hipertensão
KR101661952B1 (ko) * 2013-03-07 2016-10-04 다우 글로벌 테크놀로지스 엘엘씨 극저점도의 신규한 에스테르화된 셀룰로스 에테르
CN108264509B (zh) * 2016-12-30 2021-05-04 复旦大学 取代的苯并噻吩并[2，3-c]四氢吡啶衍生物及其制备方法和用途
KR102403210B1 (ko) * 2020-05-08 2022-05-27 경북대학교 산학협력단 시토크롬 p450 활성 저해제 및 이의 용도
US12492178B2 (en) 2021-09-01 2025-12-09 Empathbio, Inc. Stable polymorph of R-MDMA HCl
US11912680B2 (en) 2021-12-28 2024-02-27 Empathbio, Inc. Nitric oxide releasing prodrugs of MDA and MDMA
US20240425470A1 (en) * 2023-06-09 2024-12-26 ATAI Life Sciences AG Substituted benzofuran propyl amine modulators of monoaminergic transporters

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE176226T1 (de) * 1990-11-19 1999-02-15 Du Pont Insektizide, akarizide und fungizide aminopyrimidine
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
US5169860A (en) * 1992-03-13 1992-12-08 Eli Lilly And Company Antitumor compositions and methods of treatment
PH30929A (en) 1992-09-03 1997-12-23 Janssen Pharmaceutica Nv Beads having a core coated with an antifungal and a polymer.
US5529999A (en) * 1994-03-04 1996-06-25 Eli Lilly And Company Antitumor compositions and methods of treatment
US5756533A (en) * 1995-03-10 1998-05-26 G.D. Searle & Co. Amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
US6150556A (en) * 1995-03-10 2000-11-21 G. D. Dearle & Co. Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
EP1188766A1 (en) * 1995-03-10 2002-03-20 G.D. Searle & Co. Bis-amino acid hydroxyethylamino sulfonamide retroviral protease inhibitors
US5705500A (en) * 1995-03-10 1998-01-06 G.D. Searle & Co. Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
BR9607625A (pt) * 1995-03-10 1999-06-15 Searle & Co Inibidores de protease retroviral sulfonamida hidroxietilamino de aminoácido heterociclocarbonila
US5753660A (en) * 1995-11-15 1998-05-19 G. D. Searle & Co. Substituted sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
WO1997044014A1 (en) 1996-05-20 1997-11-27 Janssen Pharmaceutica N.V. Antifungal compositions with improved bioavailability
SK284813B6 (sk) 1997-03-26 2005-12-01 Janssen Pharmaceutica N. V. Peleta obsahujúca itrakonazol, spôsob jej prípravy a farmaceutická dávková forma s jej obsahom
JP2000212182A (ja) * 1999-01-20 2000-08-02 Mitsui Chemicals Inc ビシクロイミダゾ―ル誘導体及びそれを有効成分として含有する殺虫剤
TNSN00027A1 (fr) 1999-02-12 2005-11-10 Vertex Pharma Inhibiteurs de l'aspartyle protease
ID30355A (id) * 1999-04-07 2001-11-22 Pfizer Prod Inc Penggunaan inhibitor-inhibitor cyp2d6 dalam terapi kombinasi
US6564152B2 (en) * 2000-01-26 2003-05-13 Pfizer Inc Pharmacophore models for, methods of screening for, and identification of the cytochrome P-450 inhibitory potency of neurokinin-1 receptor antagonists
US20050043304A1 (en) * 2001-08-01 2005-02-24 Yutaka Kato Novel amine derivative having human beta-tryptase inhibitory activity and drugs containing the same
US6740676B2 (en) * 2002-03-19 2004-05-25 Allergan, Inc. 4-[(8-ethynyl, 8-vinyl or 8-ethynyl-methyl)-6-chromanoyl]-benzoic and 2-[4-[(8-ethynyl, 8-vinyl or 8-ethynyl-methyl)-6-chromanoyl]-phenyl]-acetic acid, their esters and salts having cytochrome p450rai inhibitory activity
WO2004043903A1 (en) * 2002-11-05 2004-05-27 Eli Lilly And Company 3-aryloxy/ thio-2, 3-substituted propanamines and their use in inhibiting serotonin and norepinephrine reuptake
DE60316984T2 (de) * 2002-11-22 2008-07-17 Eli Lilly And Co., Indianapolis Benzoylsulfonamide als antitumor-mittel
WO2005092885A1 (en) * 2004-02-27 2005-10-06 Eli Lilly And Company 4-amino-piperidine derivatives as monoamine uptake inhibitors
US7378441B2 (en) * 2004-05-07 2008-05-27 Sequoia Pharmaceuticals, Inc. Resistance-repellent retroviral protease inhibitors
DK1828167T3 (da) * 2004-06-04 2014-10-20 Debiopharm Int Sa Acrylamidderivater som antibiotiske midler
AR053845A1 (es) * 2005-04-15 2007-05-23 Tibotec Pharm Ltd 5-tiazolilmetil[(1s,2r)-3-[[(2-amino-6-benzoxazolil)sulfonil)](2-metilpropil)amino]-2-hidroxi-1-(fenilmetil)propil]carbamato como mejorador de farmacos metabolizados por el citocromo p450
EP1717233A1 (en) 2005-04-29 2006-11-02 Bioprojet Histamine H3-receptor ligands and their therapeutic application
WO2007111866A2 (en) * 2006-03-23 2007-10-04 Schering Corporation Combinations of hcv protease inhibitor(s) and cyp3a4 inhibitor(s), and methods of treatment related thereto
US7703126B2 (en) 2006-03-31 2010-04-20 Intel Corporation Hierarchical trust based posture reporting and policy enforcement
AU2007285759B2 (en) * 2006-08-18 2013-11-21 Sequoia Pharmaceuticals, Inc. Compositions and methods for inhibiting cytochrome P450
US8569364B2 (en) * 2007-11-28 2013-10-29 Sequoia Pharmaceuticals, Inc. 5-substituted benzofurans as inhibitors of cytochrome P450 2D6

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