JP2011504375A - 細胞の中に核酸を導入する医薬組成物及びその方法 - Google Patents
細胞の中に核酸を導入する医薬組成物及びその方法 Download PDFInfo
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
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- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/95—Fusion polypeptide containing a motif/fusion for degradation (ubiquitin fusions, PEST sequence)
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- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/915—Therapeutic or pharmaceutical composition
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
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- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99012407P | 2007-11-26 | 2007-11-26 | |
| PCT/KR2008/006962 WO2009069935A2 (en) | 2007-11-26 | 2008-11-26 | Pharmaceutical compositions and methods for delivering nucleic acids into cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011504375A true JP2011504375A (ja) | 2011-02-10 |
| JP2011504375A5 JP2011504375A5 (https=) | 2012-01-05 |
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| Application Number | Title | Priority Date | Filing Date |
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| JP2010535876A Pending JP2011504375A (ja) | 2007-11-26 | 2008-11-26 | 細胞の中に核酸を導入する医薬組成物及びその方法 |
Country Status (5)
| Country | Link |
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| US (1) | US7981446B2 (https=) |
| EP (1) | EP2220228A4 (https=) |
| JP (1) | JP2011504375A (https=) |
| KR (1) | KR20100109912A (https=) |
| WO (1) | WO2009069935A2 (https=) |
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| KR20080084937A (ko) * | 2005-11-04 | 2008-09-22 | 포휴먼텍(주) | 융합 폴리펩타이드를 세포로 전달하는 방법 |
| WO2011133112A1 (en) * | 2010-04-20 | 2011-10-27 | National University Of Singapore | Cell penetrating peptide derived from the premembrane protein of flavivirus |
| US9801948B2 (en) | 2011-09-21 | 2017-10-31 | Yale University | Antimicrobial compositions and methods of use thereof |
| CN103088065B (zh) * | 2013-01-25 | 2014-12-10 | 北京银杏德济生物技术有限公司 | 一种能够大规模并快速高纯度地诱导间充质干细胞转决定成造血干细胞的方法 |
| CN109414414A (zh) | 2016-03-16 | 2019-03-01 | 戴维·格拉德斯通研究所 | 用于治疗肥胖症和/或糖尿病以及用于鉴定候选治疗剂的方法和组合物 |
| GR1010063B (el) * | 2019-11-11 | 2021-08-20 | Αριστοτελειο Πανεπιστημιο Θεσσαλονικης-Ειδικος Λογαριασμος Κονδυλιων Ερευνας | Μεθοδος για την αναπτυξη μιας πλατφορμας για την παραγωγη δυναμενων για μεταφορα μεσω πεπτιδιου μεταγωγης (ptd), in vitro μεταγραφομενων (ivt) mrna θεραπευτικων |
| CN114644686B (zh) * | 2022-03-24 | 2023-09-05 | 中国人民解放军陆军军医大学 | 一种用于dna疫苗递送系统及其应用和dna疫苗 |
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- 2008-11-26 KR KR1020107013994A patent/KR20100109912A/ko not_active Withdrawn
- 2008-11-26 JP JP2010535876A patent/JP2011504375A/ja active Pending
- 2008-11-26 EP EP08854303A patent/EP2220228A4/en not_active Withdrawn
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| WO2009069935A2 (en) | 2009-06-04 |
| WO2009069935A3 (en) | 2009-09-03 |
| EP2220228A2 (en) | 2010-08-25 |
| KR20100109912A (ko) | 2010-10-11 |
| EP2220228A4 (en) | 2011-05-18 |
| US7981446B2 (en) | 2011-07-19 |
| US20090162857A1 (en) | 2009-06-25 |
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