JP2011503193A - ヒトホスファチジルイノシトール3−キナーゼδの阻害剤 - Google Patents

ヒトホスファチジルイノシトール3−キナーゼδの阻害剤 Download PDF

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JP2011503193A
JP2011503193A JP2010534149A JP2010534149A JP2011503193A JP 2011503193 A JP2011503193 A JP 2011503193A JP 2010534149 A JP2010534149 A JP 2010534149A JP 2010534149 A JP2010534149 A JP 2010534149A JP 2011503193 A JP2011503193 A JP 2011503193A
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alkylene
substituted
unsubstituted
aryl
heteroaryl
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JP2011503193A5 (OSRAM
Inventor
スティーブン エル. ホワイト,
フーキアン ルアン,
エドワード エー. ケシキ,
ユージーン ソーセット,
フランシン ファロウズ,
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Icos Corp
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Icos Corp
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
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    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • A—HUMAN NECESSITIES
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    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Engineering & Computer Science (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
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  • Transplantation (AREA)
  • Emergency Medicine (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Otolaryngology (AREA)
JP2010534149A 2007-11-13 2008-11-12 ヒトホスファチジルイノシトール3−キナーゼδの阻害剤 Pending JP2011503193A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98772307P 2007-11-13 2007-11-13
PCT/US2008/083262 WO2009064802A2 (en) 2007-11-13 2008-11-12 Inhibitors of human phosphatidyl-inositol 3-kinase delta

Publications (2)

Publication Number Publication Date
JP2011503193A true JP2011503193A (ja) 2011-01-27
JP2011503193A5 JP2011503193A5 (OSRAM) 2012-12-20

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JP2010534149A Pending JP2011503193A (ja) 2007-11-13 2008-11-12 ヒトホスファチジルイノシトール3−キナーゼδの阻害剤

Country Status (13)

Country Link
US (1) US20110021541A1 (OSRAM)
EP (1) EP2220089A4 (OSRAM)
JP (1) JP2011503193A (OSRAM)
KR (1) KR20100119745A (OSRAM)
CN (1) CN101952292A (OSRAM)
AU (1) AU2008321099A1 (OSRAM)
CA (1) CA2716334A1 (OSRAM)
EA (1) EA201070611A1 (OSRAM)
GE (1) GEP20125635B (OSRAM)
IL (1) IL205747A0 (OSRAM)
NZ (1) NZ585460A (OSRAM)
SG (1) SG185996A1 (OSRAM)
WO (1) WO2009064802A2 (OSRAM)

Cited By (4)

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JP2011508782A (ja) * 2008-01-04 2011-03-17 インテリカイン, インコーポレイテッド 特定の化学的実体、組成物および方法
JP2014520888A (ja) * 2011-07-19 2014-08-25 インフィニティー ファーマシューティカルズ, インコーポレイテッド 複素環式化合物及びその使用
JP2014520887A (ja) * 2011-07-19 2014-08-25 インフィニティー ファーマシューティカルズ, インコーポレイテッド 複素環式化合物及びその使用
JP2015509509A (ja) * 2012-03-06 2015-03-30 ベイジン ウェイフオン イーミーン バイオ−テクノロジー リミティドカンパニー 慢性閉塞性疾患を治療するための医薬品組成物の製造のための、ルパタジンの使用

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EA200870409A1 (ru) 2006-04-04 2009-04-28 Дзе Риджентс Оф Дзе Юниверсити Оф Калифорния Антагонисты киназы pi3
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CA2740885C (en) 2008-10-16 2018-04-03 The Regents Of The University Of California Fused ring heteroaryl kinase inhibitors
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JP2013545749A (ja) * 2010-11-10 2013-12-26 インフィニティー ファーマシューティカルズ, インコーポレイテッド 複素環化合物及びその使用
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JP6117235B2 (ja) 2011-12-15 2017-04-19 ノバルティス アーゲー Pi3kの活性または機能の阻害剤の使用
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