EA201070611A1 - Ингибиторы человеческой фосфатидилинозитол-3-киназы дельта - Google Patents
Ингибиторы человеческой фосфатидилинозитол-3-киназы дельтаInfo
- Publication number
- EA201070611A1 EA201070611A1 EA201070611A EA201070611A EA201070611A1 EA 201070611 A1 EA201070611 A1 EA 201070611A1 EA 201070611 A EA201070611 A EA 201070611A EA 201070611 A EA201070611 A EA 201070611A EA 201070611 A1 EA201070611 A1 EA 201070611A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- pi3kδ
- kinase delta
- delta inhibitors
- human phosphatidylinositol
- activity
- Prior art date
Links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
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- Chemical & Material Sciences (AREA)
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- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
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- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
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Abstract
Раскрыты соединения, которые ингибируют активность PI3Kδ, включая соединения, которые избирательно ингибируют активность PI3Kδ. Раскрыты также способы ингибирования активности дельта-изоформы фосфатидилинозитол-3-киназы (PI3Kδ) и способы лечения заболеваний, таких как заболевания иммунной системы и воспаление, при которых PI3Kδ играет роль в функции лейкоцитов, при помощи данных соединений.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US98772307P | 2007-11-13 | 2007-11-13 | |
PCT/US2008/083262 WO2009064802A2 (en) | 2007-11-13 | 2008-11-12 | Inhibitors of human phosphatidyl-inositol 3-kinase delta |
Publications (1)
Publication Number | Publication Date |
---|---|
EA201070611A1 true EA201070611A1 (ru) | 2010-12-30 |
Family
ID=40639422
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201070611A EA201070611A1 (ru) | 2007-11-13 | 2008-11-12 | Ингибиторы человеческой фосфатидилинозитол-3-киназы дельта |
Country Status (13)
Country | Link |
---|---|
US (1) | US20110021541A1 (ru) |
EP (1) | EP2220089A4 (ru) |
JP (1) | JP2011503193A (ru) |
KR (1) | KR20100119745A (ru) |
CN (1) | CN101952292A (ru) |
AU (1) | AU2008321099A1 (ru) |
CA (1) | CA2716334A1 (ru) |
EA (1) | EA201070611A1 (ru) |
GE (1) | GEP20125635B (ru) |
IL (1) | IL205747A0 (ru) |
NZ (1) | NZ585460A (ru) |
SG (1) | SG185996A1 (ru) |
WO (1) | WO2009064802A2 (ru) |
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DE10238722A1 (de) | 2002-08-23 | 2004-03-11 | Bayer Ag | Selektive Phosphodiesterase 9A-Inhibitoren als Arzneimittel zur Verbesserung kognitiver Prozesse |
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WO2006068760A2 (en) | 2004-11-19 | 2006-06-29 | The Regents Of The University Of California | Anti-inflammatory pyrazolopyrimidines |
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WO2011047384A2 (en) | 2009-10-16 | 2011-04-21 | The Regents Of The University Of California | Methods of inhibiting ire1 |
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US4782137A (en) * | 1984-01-24 | 1988-11-01 | Immunex Corporation | Synthesis of protein with an identification peptide, and hybrid polypeptide incorporating same |
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US5011912A (en) * | 1986-12-19 | 1991-04-30 | Immunex Corporation | Hybridoma and monoclonal antibody for use in an immunoaffinity purification system |
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2008
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- 2008-11-12 WO PCT/US2008/083262 patent/WO2009064802A2/en active Application Filing
- 2008-11-12 JP JP2010534149A patent/JP2011503193A/ja active Pending
- 2008-11-12 CA CA2716334A patent/CA2716334A1/en not_active Abandoned
- 2008-11-12 AU AU2008321099A patent/AU2008321099A1/en not_active Abandoned
- 2008-11-12 KR KR1020107013006A patent/KR20100119745A/ko not_active Application Discontinuation
- 2008-11-12 NZ NZ585460A patent/NZ585460A/xx not_active IP Right Cessation
- 2008-11-12 GE GEAP200811842A patent/GEP20125635B/en unknown
- 2008-11-12 EA EA201070611A patent/EA201070611A1/ru unknown
- 2008-11-12 SG SG2012083556A patent/SG185996A1/en unknown
- 2008-11-12 CN CN2008801245653A patent/CN101952292A/zh active Pending
- 2008-11-12 US US12/742,904 patent/US20110021541A1/en not_active Abandoned
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EP2220089A4 (en) | 2011-10-26 |
KR20100119745A (ko) | 2010-11-10 |
GEP20125635B (en) | 2012-09-10 |
SG185996A1 (en) | 2012-12-28 |
WO2009064802A3 (en) | 2009-07-02 |
CA2716334A1 (en) | 2009-05-22 |
JP2011503193A (ja) | 2011-01-27 |
WO2009064802A2 (en) | 2009-05-22 |
EP2220089A2 (en) | 2010-08-25 |
US20110021541A1 (en) | 2011-01-27 |
IL205747A0 (en) | 2010-11-30 |
NZ585460A (en) | 2013-02-22 |
AU2008321099A1 (en) | 2009-05-22 |
CN101952292A (zh) | 2011-01-19 |
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