JP2011501970A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2011501970A5 JP2011501970A5 JP2010532268A JP2010532268A JP2011501970A5 JP 2011501970 A5 JP2011501970 A5 JP 2011501970A5 JP 2010532268 A JP2010532268 A JP 2010532268A JP 2010532268 A JP2010532268 A JP 2010532268A JP 2011501970 A5 JP2011501970 A5 JP 2011501970A5
- Authority
- JP
- Japan
- Prior art keywords
- glutaraldehyde
- enzyme catalyst
- catalyst
- produced
- pretreatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003054 catalyst Substances 0.000 claims 13
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 claims 9
- 238000000034 method Methods 0.000 claims 9
- 108090000790 Enzymes Proteins 0.000 claims 8
- 102000004190 Enzymes Human genes 0.000 claims 8
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 claims 6
- 230000000694 effects Effects 0.000 claims 4
- 238000000855 fermentation Methods 0.000 claims 3
- 230000004151 fermentation Effects 0.000 claims 3
- 108010093096 Immobilized Enzymes Proteins 0.000 claims 2
- 108010033272 Nitrilase Proteins 0.000 claims 2
- 239000007864 aqueous solution Substances 0.000 claims 2
- 229940113118 carrageenan Drugs 0.000 claims 2
- 235000010418 carrageenan Nutrition 0.000 claims 2
- 229920001525 carrageenan Polymers 0.000 claims 2
- 239000000679 carrageenan Substances 0.000 claims 2
- LTYRAPJYLUPLCI-UHFFFAOYSA-N glycolonitrile Chemical compound OCC#N LTYRAPJYLUPLCI-UHFFFAOYSA-N 0.000 claims 2
- JMANVNJQNLATNU-UHFFFAOYSA-N glycolonitrile Natural products N#CC#N JMANVNJQNLATNU-UHFFFAOYSA-N 0.000 claims 2
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims 2
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 claims 1
- 229920002873 Polyethylenimine Polymers 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 238000004132 cross linking Methods 0.000 claims 1
- 230000003301 hydrolyzing effect Effects 0.000 claims 1
- 230000003100 immobilizing effect Effects 0.000 claims 1
- 230000000415 inactivating effect Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/930,744 US7741088B2 (en) | 2007-10-31 | 2007-10-31 | Immobilized microbial nitrilase for production of glycolic acid |
| US11/930,744 | 2007-10-31 | ||
| PCT/US2008/081952 WO2009059104A1 (en) | 2007-10-31 | 2008-10-31 | Improvement in immobilized microbial nitrilase for production of glycolic acid |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011501970A JP2011501970A (ja) | 2011-01-20 |
| JP2011501970A5 true JP2011501970A5 (cg-RX-API-DMAC7.html) | 2011-12-15 |
| JP5583586B2 JP5583586B2 (ja) | 2014-09-03 |
Family
ID=40229742
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010532268A Active JP5583586B2 (ja) | 2007-10-31 | 2008-10-31 | グリコール酸の生産のための固定化微生物ニトリラーゼの改善 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7741088B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2215226B9 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5583586B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN102016018B (cg-RX-API-DMAC7.html) |
| DK (1) | DK2215226T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2562791T3 (cg-RX-API-DMAC7.html) |
| PL (1) | PL2215226T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2009059104A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2774692C (en) * | 2009-09-24 | 2017-12-19 | Ucb Pharma S.A. | Bacterial strain for recombinant protein expression, having protease deficient degp retaining chaperone activity, and knocked out tsp and ptr genes |
| WO2011129820A1 (en) * | 2010-04-14 | 2011-10-20 | Strategic Enzyme Applications, Inc. | Process for producing phosphinothricin employing nitrilases |
| CA2803959C (en) | 2010-06-30 | 2021-01-19 | Codexis, Inc. | Chemically modified carbonic anhydrases useful in carbon capture systems |
| ES2549593T3 (es) * | 2010-10-12 | 2015-10-29 | C-Lecta Gmbh | Nitrilasas con actividad mejorada |
| EP3354742A1 (en) | 2017-01-26 | 2018-08-01 | Metabolic Explorer | Methods and microorganisms for the production of glycolic acid and/or glyoxylic acid |
| CN108486088B (zh) * | 2018-02-14 | 2021-02-02 | 浙江工业大学 | 腈水解酶突变体及其应用 |
| CN113195727A (zh) * | 2018-10-18 | 2021-07-30 | 巴斯夫欧洲公司 | 用于产生丙烯酸或其盐的方法 |
| CN112063607B (zh) * | 2020-10-09 | 2021-12-07 | 浙江工业大学 | 一种腈水解酶突变体及其在催化合成2-氯烟酸中的应用 |
| CN119570649A (zh) * | 2024-07-12 | 2025-03-07 | 北京衍微科技有限公司 | 含红球菌发酵液的复合催化剂及其用途 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2175805A (en) * | 1937-06-08 | 1939-10-10 | Du Pont | Stabilized organic nitrile and process of making |
| US2890238A (en) * | 1957-01-31 | 1959-06-09 | Dow Chemical Co | Preparation of glyconitrile |
| FR2245585B1 (cg-RX-API-DMAC7.html) | 1973-09-19 | 1976-05-14 | Anvar | |
| DK146942C (da) * | 1978-04-19 | 1984-07-30 | Novo Industri As | Fremgangsmaade til fremstilling af et immobiliseret enzymprodukt |
| US4355105A (en) * | 1981-03-30 | 1982-10-19 | Miles Laboratories, Inc. | Glutaraldehyde/polyethylenimine immobilization of whole microbial cells |
| JPS6156086A (ja) | 1984-08-27 | 1986-03-20 | Asahi Chem Ind Co Ltd | α−オキシ酸およびその塩の微生物学的製造法 |
| US5187301A (en) * | 1989-10-26 | 1993-02-16 | W. R. Grace & Co.-Conn. | Preparation of iminodiacetonitrile from glycolonitrile |
| EP0449648B1 (en) | 1990-03-30 | 1999-05-12 | Nitto Chemical Industry Co., Ltd. | Process for producing R(-)-mandelic acid and derivatives thereof |
| JP2974737B2 (ja) | 1990-08-16 | 1999-11-10 | 三菱レイヨン株式会社 | 光学活性乳酸の製造法 |
| EP0486289B1 (en) | 1990-11-14 | 1997-07-09 | Nitto Chemical Industry Co., Ltd. | Biological process for producing alpha-hydroxyamide or alpha-hydroxy acid |
| JP2676568B2 (ja) | 1991-06-26 | 1997-11-17 | 日東化学工業株式会社 | Ｒ（−）−マンデル酸およびその誘導体の製造法 |
| US5846762A (en) * | 1992-08-26 | 1998-12-08 | Lockheed Martin Energy Research Systems, Inc. | Structurally stable gel bead containing entrapped enzyme and method for manufacture thereof |
| JP2720140B2 (ja) | 1993-02-03 | 1998-02-25 | 日東化学工業株式会社 | フェニル基を有する光学活性α−ヒドロキシカルボン酸の製造法 |
| JP3218133B2 (ja) | 1993-02-03 | 2001-10-15 | 三菱レイヨン株式会社 | フェニル基を有する光学活性α−ヒドロキシカルボン酸の製造法 |
| JP3354688B2 (ja) * | 1994-01-28 | 2002-12-09 | 三菱レイヨン株式会社 | 微生物によるα−ヒドロキシ酸またはα−ヒドロキシアミドの製造法 |
| US5837458A (en) | 1994-02-17 | 1998-11-17 | Maxygen, Inc. | Methods and compositions for cellular and metabolic engineering |
| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| JP3154646B2 (ja) | 1995-07-19 | 2001-04-09 | 三菱レイヨン株式会社 | グリコール酸の微生物学的製造法 |
| EP0773297B2 (en) | 1995-11-10 | 2008-04-23 | Mitsubishi Rayon Co., Ltd. | Process for producing alpha-hydroxy acid or alpha-hydroxyamide by microorganism |
| GB9525372D0 (en) * | 1995-12-12 | 1996-02-14 | Allied Colloids Ltd | Enzymes, their preparation and their use in the production of ammonium acrylate |
| US5858736A (en) | 1996-05-17 | 1999-01-12 | E. I. Du Pont De Nemours And Company | Preparation of lactams from aliphatic α,ω-dinitriles |
| US6037155A (en) * | 1997-02-27 | 2000-03-14 | Nippon Soda Co., Ltd. | Process for preparing α-hydroxy acids using microorganism and novel microorganism |
| US6291708B1 (en) | 1999-04-28 | 2001-09-18 | A.E. Staley Manufacturing Co. | Process for production of organic acids and esters thereof |
| US6251646B1 (en) * | 1999-07-12 | 2001-06-26 | E. I. Du Pont De Nemours And Company | Method for stabilizing nitrilase activity and preserving microbial cells |
| US6551804B2 (en) * | 1999-07-12 | 2003-04-22 | E. I. Du Pont De Nemours And Company | Process for preparing 4-cyanopentanoic acid |
| CN100334196C (zh) * | 1999-11-12 | 2007-08-29 | 三菱丽阳株式会社 | 灭活的微生物细胞 |
| ATE495244T1 (de) * | 2000-03-31 | 2011-01-15 | Du Pont | Isolierung und expression eines nitrilase-gens von acidovorax facilis 72w |
| US6416980B1 (en) * | 2001-02-23 | 2002-07-09 | E. I. Du Pont De Nemours & Company | Method for producing glycolic acid from glycolonitrile using nitrilase |
| MXPA03010183A (es) | 2001-05-07 | 2004-03-16 | Cargill Inc | Proceso para preparar acidos carboxilicos y derivados de los mismos. |
| TW200407300A (en) | 2002-07-12 | 2004-05-16 | Nippon Catalytic Chem Ind | Process for producing diol derivative |
| JP4523939B2 (ja) | 2004-04-27 | 2010-08-11 | 三井化学株式会社 | ヒドロキシカルボン酸類の生産方法 |
| US7148051B2 (en) * | 2004-08-16 | 2006-12-12 | E. I. Du Pont De Nemours And Company | Production of 3-hydroxycarboxylic acid using nitrilase |
| EP1828393B1 (en) | 2004-12-22 | 2012-11-07 | E.I. Du Pont De Nemours And Company | Process for producing glycolic acid from formaldehyde and hydrogen cyanide |
| JP5155666B2 (ja) * | 2004-12-22 | 2013-03-06 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | グリコロニトリルの合成のための方法 |
| US7445917B2 (en) * | 2004-12-22 | 2008-11-04 | E.I. Du Pont De Nemours And Company | Process for producing glycolic acid from formaldehyde and hydrogen cyanide |
| CN102796770B (zh) | 2004-12-22 | 2014-06-04 | 纳幕尔杜邦公司 | 乙醇酸的酶促生产 |
| US7198927B2 (en) * | 2004-12-22 | 2007-04-03 | E. I. Du Pont De Nemours And Company | Enzymatic production of glycolic acid |
| DE102005015570A1 (de) | 2005-04-05 | 2006-10-12 | Robert Bosch Gmbh | Druckregelventil |
| EP1934342B1 (en) | 2005-09-30 | 2014-12-10 | Novozymes A/S | Immobilization of enzymes |
-
2007
- 2007-10-31 US US11/930,744 patent/US7741088B2/en active Active
-
2008
- 2008-10-31 DK DK08845012.7T patent/DK2215226T3/en active
- 2008-10-31 EP EP08845012.7A patent/EP2215226B9/en active Active
- 2008-10-31 JP JP2010532268A patent/JP5583586B2/ja active Active
- 2008-10-31 CN CN2008801241192A patent/CN102016018B/zh not_active Expired - Fee Related
- 2008-10-31 ES ES08845012.7T patent/ES2562791T3/es active Active
- 2008-10-31 WO PCT/US2008/081952 patent/WO2009059104A1/en not_active Ceased
- 2008-10-31 PL PL08845012T patent/PL2215226T3/pl unknown
-
2010
- 2010-02-02 US US12/698,775 patent/US7867748B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2011501970A5 (cg-RX-API-DMAC7.html) | ||
| EA201001435A1 (ru) | Клетка, ферментирующая сахар-пентозу | |
| EP0934419B1 (fr) | Procede de preparation de l'acide 2-hydroxy 4-methylthio butyrique par utilisation d'une nitrilase | |
| CN105624128B (zh) | 一种固定化单胺氧化酶及其在合成手性氮杂双环化合物中的应用 | |
| CN112458108A (zh) | 一种在谷氨酸棒状杆菌中利用木糖生成谷氨酸的合成路径的构建方法 | |
| CN103757042B (zh) | 基于自聚集短肽诱导的固定化腈水解酶及制备方法和应用 | |
| Godoy et al. | Site-directing an intense multipoint covalent attachment (MCA) of mutants of the Geobacillus thermocatenulatus lipase 2 (BTL2): Genetic and chemical amination plus immobilization on a tailor-made support | |
| JP2011501970A (ja) | グリコール酸の生産のための固定化微生物ニトリラーゼの改善 | |
| CN104878024A (zh) | 一株重组大肠杆菌的构建及其合成(s)-2-羟基-3-苯基丙酸的方法 | |
| JP2011501969A5 (cg-RX-API-DMAC7.html) | ||
| CN105296409B (zh) | 一株用于生产固定化碱性果胶酶纳米微球的工程菌及其构建方法与应用 | |
| JP2007533329A5 (cg-RX-API-DMAC7.html) | ||
| CN117757762A (zh) | 一种大球盖菇来源的真菌漆酶、真菌漆酶基因及其应用 | |
| Pei et al. | Catalytically active inclusion bodies (CatIBs) induced by terminally attached self-assembling coiled-coil domains: To enhance the stability of (R)-hydroxynitrile lyase | |
| JPWO2014156736A1 (ja) | 微生物の固定化及び脱離方法 | |
| Ferner‐Ortner‐Bleckmann et al. | Surface‐layer lattices as patterning element for multimeric extremozymes | |
| CN103343115A (zh) | 一种磁性固定化细胞及其制备方法和应用 | |
| CN104830814A (zh) | 一种羰基还原酶及其在制备(r)-奎宁醇中的应用 | |
| CN111518851B (zh) | 一种固定化酶连续制备[14/15n]-l-瓜氨酸的方法 | |
| JPWO2019168203A5 (cg-RX-API-DMAC7.html) | ||
| CN109929829B (zh) | 一种羰基还原酶的固定化方法 | |
| JP6610868B2 (ja) | 微生物の着脱及び脱離方法 | |
| RU2002126236A (ru) | Иммобилизованный биокатализатор, способ его получения и способ получения молочной кислоты с использованием этого биокатализатора | |
| KR100589121B1 (ko) | 효소반응을 이용한 ｌ-오르니틴의 제조방법 | |
| WO2014087921A1 (ja) | １，４－ブタンジオールの製造方法、微生物及び遺伝子 |