JP2011500801A5 - - Google Patents

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JP2011500801A5
JP2011500801A5 JP2010530989A JP2010530989A JP2011500801A5 JP 2011500801 A5 JP2011500801 A5 JP 2011500801A5 JP 2010530989 A JP2010530989 A JP 2010530989A JP 2010530989 A JP2010530989 A JP 2010530989A JP 2011500801 A5 JP2011500801 A5 JP 2011500801A5
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optionally substituted
independently
heteroaryl
optionally
group
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JP2010530989A
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JP5635909B2 (ja
JP2011500801A (ja
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Priority claimed from PCT/US2007/089178 external-priority patent/WO2009054864A1/en
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JP2010530989A 2007-10-26 2007-12-29 Axl阻害剤として有用な多環アリール置換トリアゾール及び多環ヘテロアリール置換トリアゾール Expired - Fee Related JP5635909B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US98310707P 2007-10-26 2007-10-26
US60/983,107 2007-10-26
PCT/US2007/089178 WO2009054864A1 (en) 2007-10-26 2007-12-29 Polycyclic aryl substituted triazoles and polycyclic heteroaryl substituted triazoles useful as axl inhibitors

Publications (3)

Publication Number Publication Date
JP2011500801A JP2011500801A (ja) 2011-01-06
JP2011500801A5 true JP2011500801A5 (enExample) 2012-09-06
JP5635909B2 JP5635909B2 (ja) 2014-12-03

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JP2010530989A Expired - Fee Related JP5635909B2 (ja) 2007-10-26 2007-12-29 Axl阻害剤として有用な多環アリール置換トリアゾール及び多環ヘテロアリール置換トリアゾール

Country Status (7)

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US (2) US7935693B2 (enExample)
EP (1) EP2205592B1 (enExample)
JP (1) JP5635909B2 (enExample)
CA (1) CA2704052C (enExample)
ES (1) ES2424259T3 (enExample)
SI (1) SI2205592T1 (enExample)
WO (1) WO2009054864A1 (enExample)

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US8012965B2 (en) 2006-12-29 2011-09-06 Rigel Pharmaceuticals, Inc. Bridged bicyclic aryl and bridged bicyclic heteroaryl substituted triazoles useful as axl inhibitors
AU2007342007A1 (en) 2006-12-29 2008-07-10 Rigel Pharmaceuticals, Inc. Substituted triazoles useful as Axl inhibitors
EP2078010B1 (en) * 2006-12-29 2014-01-29 Rigel Pharmaceuticals, Inc. Polycyclic heteroaryl substituted triazoles useful as axl inhibitors
ES2424259T3 (es) * 2007-10-26 2013-09-30 Rigel Pharmaceuticals, Inc. Triazoles sustituidos con arilo policíclico y heteroarilo policíclico, útiles como agentes inhibidores del Axl
LT2265607T (lt) 2008-02-15 2017-03-27 Rigel Pharmaceuticals, Inc. Pirimidin-2-amino junginiai ir jų panaudojimas kaip jak kinazių slopiklių
WO2010005879A1 (en) 2008-07-09 2010-01-14 Rigel Pharmaceuticals, Inc. Bridged bicyclic heteroaryl substituted triazoles useful as axl inhibitors
JP5592884B2 (ja) * 2008-07-09 2014-09-17 ライジェル ファーマシューティカルズ, インコーポレイテッド Axl阻害剤として有用な多環式ヘテロアリール置換トリアゾール
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WO2021048292A1 (en) 2019-09-11 2021-03-18 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and compositions for treating melanoma
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CA3157889A1 (en) 2019-10-17 2021-04-22 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods for diagnosing nasal intestinal type adenocarcinomas
EP4051286A1 (en) 2019-10-29 2022-09-07 Institut National de la Santé et de la Recherche Médicale (INSERM) Methods and compositions for treating uveal melanoma
KR20220098759A (ko) 2019-11-08 2022-07-12 인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) 키나제 억제제에 대해 내성을 획득한 암의 치료 방법
CA3164754A1 (en) 2019-12-19 2021-06-24 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods and vaccine compositions to treat cancers
EP4090770A1 (en) 2020-01-17 2022-11-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and compositions for treating melanoma
WO2021148581A1 (en) 2020-01-22 2021-07-29 Onxeo Novel dbait molecule and its use
EP4100126A1 (en) 2020-02-05 2022-12-14 Institut National de la Santé et de la Recherche Médicale (INSERM) Methods for discontinuing a treatment with a tyrosine kinase inhibitor (tki)
WO2021170777A1 (en) 2020-02-28 2021-09-02 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for diagnosing, prognosing and managing treatment of breast cancer
JP2023516441A (ja) 2020-03-06 2023-04-19 インサイト・コーポレイション Axl/mer阻害剤及びpd-1/pd-l1阻害剤を含む併用療法
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GB202006072D0 (en) 2020-04-24 2020-06-10 Bergenbio Asa Method of selecting patients for treatment with cmbination therapy
JP2023535610A (ja) 2020-07-28 2023-08-18 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル ガンを予防及び処置するための方法及び組成物
WO2022084531A1 (en) 2020-10-23 2022-04-28 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and compositions for treating glioma
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EP4244392A1 (en) 2020-11-16 2023-09-20 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods and compositions for predicting and treating uveal melanoma
EP4308118A1 (en) 2021-03-17 2024-01-24 Institut National de la Santé et de la Recherche Médicale (INSERM) Methods and compositions for treating melanoma
GB202104037D0 (en) 2021-03-23 2021-05-05 Bergenbio Asa Combination therapy
US20240158861A1 (en) 2021-04-23 2024-05-16 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and compositions for treating cell senescence accumulation related disease
US20240426823A1 (en) 2021-11-03 2024-12-26 Institut National de la Santé et de la Recherche Médicale Methods and compositions for treating triple negative breast cancer (tnbc)
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GB202209285D0 (en) 2022-06-24 2022-08-10 Bergenbio Asa Dosage regimen for AXL inhibitor
EP4568670A1 (en) 2022-08-10 2025-06-18 Institut National de la Santé et de la Recherche Médicale Sigmar1 ligand for the treatment of pancreatic cancer
WO2024033400A1 (en) 2022-08-10 2024-02-15 Institut National de la Santé et de la Recherche Médicale Sk2 inhibitor for the treatment of pancreatic cancer
WO2024051667A1 (zh) * 2022-09-05 2024-03-14 南京正大天晴制药有限公司 具有axl抑制活性的取代三唑化合物
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