JP2011500693A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2011500693A5 JP2011500693A5 JP2010530049A JP2010530049A JP2011500693A5 JP 2011500693 A5 JP2011500693 A5 JP 2011500693A5 JP 2010530049 A JP2010530049 A JP 2010530049A JP 2010530049 A JP2010530049 A JP 2010530049A JP 2011500693 A5 JP2011500693 A5 JP 2011500693A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- bipyrrolidinyl
- phenyl
- amide
- carboxylic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98059907P | 2007-10-17 | 2007-10-17 | |
| US60/980,599 | 2007-10-17 | ||
| PCT/US2008/079757 WO2009052062A1 (en) | 2007-10-17 | 2008-10-14 | Substituted n-phenyl-bipyrrolidine carboxamides and therapeutic use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011500693A JP2011500693A (ja) | 2011-01-06 |
| JP2011500693A5 true JP2011500693A5 (https=) | 2011-12-01 |
| JP5377503B2 JP5377503B2 (ja) | 2013-12-25 |
Family
ID=40247942
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010530049A Expired - Fee Related JP5377503B2 (ja) | 2007-10-17 | 2008-10-14 | 置換されたｎ−フェニル−ビピロリジンカルボキサミド及びその治療上の使用 |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US8088808B2 (https=) |
| EP (1) | EP2212283B1 (https=) |
| JP (1) | JP5377503B2 (https=) |
| KR (1) | KR20100072077A (https=) |
| CN (1) | CN101903340B (https=) |
| AT (1) | ATE525351T1 (https=) |
| AU (1) | AU2008312635B2 (https=) |
| BR (1) | BRPI0818581A2 (https=) |
| CA (1) | CA2702467C (https=) |
| CY (1) | CY1112083T1 (https=) |
| DK (1) | DK2212283T3 (https=) |
| ES (1) | ES2372332T3 (https=) |
| HR (1) | HRP20110762T1 (https=) |
| IL (1) | IL205001A (https=) |
| MA (1) | MA31858B1 (https=) |
| MX (1) | MX2010003949A (https=) |
| MY (1) | MY151348A (https=) |
| NZ (1) | NZ584690A (https=) |
| PL (1) | PL2212283T3 (https=) |
| PT (1) | PT2212283E (https=) |
| RS (1) | RS52235B (https=) |
| RU (1) | RU2477720C2 (https=) |
| SI (1) | SI2212283T1 (https=) |
| WO (1) | WO2009052062A1 (https=) |
| ZA (1) | ZA201002115B (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009052068A1 (en) | 2007-10-17 | 2009-04-23 | Sanofi-Aventis | Substituted n-phenyl-bipyrrolidine ureas and therapeutic use thereof |
| CN101903340B (zh) * | 2007-10-17 | 2013-03-27 | 赛诺菲-安万特 | 取代的n-苯基联吡咯烷羧酰胺及其治疗用途 |
| CN101903342B (zh) | 2007-10-17 | 2012-11-21 | 赛诺菲-安万特 | 取代的n-苯基-吡咯烷基甲基吡咯烷酰胺及其作为组胺h3受体调节剂的治疗用途 |
| EP2212282B1 (en) | 2007-10-17 | 2011-09-21 | Sanofi | Substituted n-phenyl-bipyrrolidine carboxamides and therapeutic use thereof |
| AR074466A1 (es) | 2008-12-05 | 2011-01-19 | Sanofi Aventis | Piperidina espiro pirrolidinona y piperidinona sustituidas y su uso terapeutico en enfermedades mediadas por la modulacion de los receptores h3. |
| AR074467A1 (es) | 2008-12-05 | 2011-01-19 | Sanofi Aventis | Tetrahidropiran espiro pirrolidinonas y piperidinonas sustituidas, composiciones farmaceuticas que las contienen y uso de las mismas en el tratamiento y/o prevencion de enfermedades del snc ,tales como alzheimer y parkinson, entre otras. |
| SA110310332B1 (ar) * | 2009-05-01 | 2013-12-10 | Astrazeneca Ab | مركبات ميثانون (3 استبدال -ازيتيدين -1-يل )(5- فينيل -1، 3، 4- أوكساديازول -2-يل ) |
| JP5833105B2 (ja) | 2010-05-11 | 2015-12-16 | サノフイ | 置換ｎ−ヘテロアリールスピロラクタムビピロリジン類、その製造及び治療的使用 |
| TW201206889A (en) | 2010-05-11 | 2012-02-16 | Sanofi Aventis | Substituted N-alkyl and N-acyl tetrahydro-isoquinoline derivatives, preparation and therapeutic use thereof |
| EP2569297A1 (en) | 2010-05-11 | 2013-03-20 | Sanofi | Substituted n-heterocycloalkyl bipyrrolidinylphenyl amide derivatives, preparation and therapeutic use thereof |
| TW201206898A (en) * | 2010-05-11 | 2012-02-16 | Sanofi Aventis | Substituted N-phenyl spirolactam bipyrrolidines, preparation and therapeutic use thereof |
| AR083718A1 (es) | 2010-05-11 | 2013-03-20 | Sanofi Aventis | Fenil cicloalquil pirrolidina (piperidina) espirolactamas y amidas sustituidas, preparacion y uso terapeutico de las mismas |
| WO2011143162A1 (en) * | 2010-05-11 | 2011-11-17 | Sanofi | Substituted n-heteroaryl bipyrrolidine carboxamides, preparation and therapeutic use thereof |
| WO2011143155A1 (en) * | 2010-05-11 | 2011-11-17 | Sanofi | Substituted n-heteroaryl tetrahydro-isoquinoline derivatives, preparation and therapeutic use thereof |
| SA111320581B1 (ar) | 2010-07-06 | 2014-06-17 | استرازينيكا ايه بي | مركبات (3-(4-(أمينو ميثيل ) فينوكسي أو فينيل ثيو) أزيتيدين -1- يل) (5- فينيل -1، 3، 4- أوكسا ديازول -2- يل) ميثانون |
| UY34194A (es) | 2011-07-15 | 2013-02-28 | Astrazeneca Ab | ?(3-(4-(espiroheterocíclico)metil)fenoxi)azetidin-1-il)(5-(fenil)-1,3,4-oxadiazol-2-il)metanona en el tratamiento de la obesidad? |
| JP2013232564A (ja) * | 2012-04-27 | 2013-11-14 | National Institute Of Advanced Industrial & Technology | 半導体装置および半導体装置の製造方法 |
| CN108250128A (zh) * | 2012-09-27 | 2018-07-06 | 江苏先声药业有限公司 | 作为钾通道调节剂的化合物 |
| JP2016508152A (ja) | 2013-01-10 | 2016-03-17 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | Ｃｒａｃチャネル阻害薬としての、ピラゾリルをベースとするカルボキサミド類ｉ |
| WO2014108336A1 (en) | 2013-01-10 | 2014-07-17 | Grünenthal GmbH | Pyrazolyl-based carboxamides ii as crac channel inhibitors |
| EP3366683A1 (en) | 2017-02-28 | 2018-08-29 | Acousia Therapeutics GmbH | Cyclic amides, acteamides and ureas useful as potassium channel openers |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20020507A1 (es) * | 2000-10-17 | 2002-06-25 | Schering Corp | Compuestos no-imidazoles como antagonistas del receptor histamina h3 |
| US7279491B2 (en) * | 2002-10-23 | 2007-10-09 | Janssen Pharmaceutica N.V. | Phenylpiperidines and phenylpyrrolidines |
| US7223788B2 (en) * | 2003-02-14 | 2007-05-29 | Sanofi-Aventis Deutschland Gmbh | Substituted N-aryl heterocycles, process for their preparation and their use as medicaments |
| DE10306250A1 (de) * | 2003-02-14 | 2004-09-09 | Aventis Pharma Deutschland Gmbh | Substituierte N-Arylheterozyklen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| AU2006227815B2 (en) | 2005-03-17 | 2011-09-22 | Eli Lilly And Company | Pyrrolidine derivatives as histamine H3 receptor antagonists |
| AU2006232871B9 (en) * | 2005-04-01 | 2011-11-24 | Eli Lilly And Company | Histamine H3 receptor agents, preparation and therapeutic uses |
| EP1904442B1 (en) * | 2005-07-01 | 2011-09-07 | Eli Lilly And Company | Histamine h3 receptor agents, preparation and therapeutic uses |
| CA2627234A1 (en) * | 2005-10-27 | 2007-05-03 | Ucb Pharma, S.A. | Compounds comprising a lactam or a lactam derivative moiety, processes for making them, and their uses |
| EP1987020B1 (en) * | 2006-02-15 | 2012-10-03 | Sanofi | Azacyclyl-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments |
| WO2009052068A1 (en) * | 2007-10-17 | 2009-04-23 | Sanofi-Aventis | Substituted n-phenyl-bipyrrolidine ureas and therapeutic use thereof |
| EP2212282B1 (en) | 2007-10-17 | 2011-09-21 | Sanofi | Substituted n-phenyl-bipyrrolidine carboxamides and therapeutic use thereof |
| CN101903340B (zh) * | 2007-10-17 | 2013-03-27 | 赛诺菲-安万特 | 取代的n-苯基联吡咯烷羧酰胺及其治疗用途 |
| CN101903342B (zh) | 2007-10-17 | 2012-11-21 | 赛诺菲-安万特 | 取代的n-苯基-吡咯烷基甲基吡咯烷酰胺及其作为组胺h3受体调节剂的治疗用途 |
-
2008
- 2008-10-14 CN CN2008801212081A patent/CN101903340B/zh not_active Expired - Fee Related
- 2008-10-14 KR KR1020107010769A patent/KR20100072077A/ko not_active Ceased
- 2008-10-14 AU AU2008312635A patent/AU2008312635B2/en not_active Ceased
- 2008-10-14 PL PL08839959T patent/PL2212283T3/pl unknown
- 2008-10-14 ES ES08839959T patent/ES2372332T3/es active Active
- 2008-10-14 RU RU2010119528/04A patent/RU2477720C2/ru not_active IP Right Cessation
- 2008-10-14 JP JP2010530049A patent/JP5377503B2/ja not_active Expired - Fee Related
- 2008-10-14 PT PT08839959T patent/PT2212283E/pt unknown
- 2008-10-14 EP EP08839959A patent/EP2212283B1/en active Active
- 2008-10-14 WO PCT/US2008/079757 patent/WO2009052062A1/en not_active Ceased
- 2008-10-14 DK DK08839959.7T patent/DK2212283T3/da active
- 2008-10-14 RS RS20110522A patent/RS52235B/sr unknown
- 2008-10-14 HR HR20110762T patent/HRP20110762T1/hr unknown
- 2008-10-14 MY MYPI20101299 patent/MY151348A/en unknown
- 2008-10-14 AT AT08839959T patent/ATE525351T1/de active
- 2008-10-14 NZ NZ584690A patent/NZ584690A/en not_active IP Right Cessation
- 2008-10-14 CA CA2702467A patent/CA2702467C/en not_active Expired - Fee Related
- 2008-10-14 SI SI200830416T patent/SI2212283T1/sl unknown
- 2008-10-14 BR BRPI0818581-6A patent/BRPI0818581A2/pt not_active IP Right Cessation
- 2008-10-14 MX MX2010003949A patent/MX2010003949A/es active IP Right Grant
-
2010
- 2010-03-15 US US12/724,028 patent/US8088808B2/en not_active Expired - Fee Related
- 2010-03-25 ZA ZA2010/02115A patent/ZA201002115B/en unknown
- 2010-04-11 IL IL205001A patent/IL205001A/en not_active IP Right Cessation
- 2010-05-17 MA MA32850A patent/MA31858B1/fr unknown
-
2011
- 2011-11-18 US US13/299,574 patent/US8252824B2/en not_active Expired - Fee Related
- 2011-11-24 CY CY20111101151T patent/CY1112083T1/el unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2011500693A5 (https=) | ||
| CA2702467A1 (en) | Substituted n-phenyl-bipyrrolidine carboxamides and therapeutic use thereof | |
| CA2702482A1 (en) | Substituted n-phenyl-bipyrrolidine carboxamides and therapeutic use thereof | |
| RU2010119530A (ru) | Замещенные n-фенилпирролидинилметилпирролидинамиды и их терапевтическое применение в качестве модуляторов рецептора н3 гистамина | |
| JP2010526777A5 (https=) | ||
| JP2011500697A5 (https=) | ||
| RU2462456C2 (ru) | Производные пиразола в качестве ингибиторов 11-бета-hsd1 | |
| JP2013518881A5 (https=) | ||
| JP2011500694A5 (https=) | ||
| CA2702933A1 (en) | Substituted n-phenyl-bipyrrolidine ureas and therapeutic use thereof | |
| CN109503625A (zh) | 一种多环吡啶酮化合物及其药物组合和用途 | |
| JP2007508358A5 (https=) | ||
| JP2006522126A5 (https=) | ||
| JP2010502716A5 (https=) | ||
| JP2009541216A5 (https=) | ||
| JP2014507455A5 (https=) | ||
| JP2012507538A5 (https=) | ||
| JP2007508360A5 (https=) | ||
| BR112012015168A2 (pt) | "derivados de benzamida substituída". | |
| JP2020527175A5 (https=) | ||
| JP2011527333A5 (https=) | ||
| JP2019525939A5 (https=) | ||
| JP2010510232A5 (https=) | ||
| RU2015131139A (ru) | Галогензамещенное гетероциклическое соединение | |
| JP2009510097A5 (https=) |