JP2011500693A5 - - Google Patents
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- Publication number
- JP2011500693A5 JP2011500693A5 JP2010530049A JP2010530049A JP2011500693A5 JP 2011500693 A5 JP2011500693 A5 JP 2011500693A5 JP 2010530049 A JP2010530049 A JP 2010530049A JP 2010530049 A JP2010530049 A JP 2010530049A JP 2011500693 A5 JP2011500693 A5 JP 2011500693A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- bipyrrolidinyl
- phenyl
- amide
- carboxylic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98059907P | 2007-10-17 | 2007-10-17 | |
| US60/980,599 | 2007-10-17 | ||
| PCT/US2008/079757 WO2009052062A1 (en) | 2007-10-17 | 2008-10-14 | Substituted n-phenyl-bipyrrolidine carboxamides and therapeutic use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011500693A JP2011500693A (ja) | 2011-01-06 |
| JP2011500693A5 true JP2011500693A5 (enExample) | 2011-12-01 |
| JP5377503B2 JP5377503B2 (ja) | 2013-12-25 |
Family
ID=40247942
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010530049A Expired - Fee Related JP5377503B2 (ja) | 2007-10-17 | 2008-10-14 | 置換されたｎ−フェニル−ビピロリジンカルボキサミド及びその治療上の使用 |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US8088808B2 (enExample) |
| EP (1) | EP2212283B1 (enExample) |
| JP (1) | JP5377503B2 (enExample) |
| KR (1) | KR20100072077A (enExample) |
| CN (1) | CN101903340B (enExample) |
| AT (1) | ATE525351T1 (enExample) |
| AU (1) | AU2008312635B2 (enExample) |
| BR (1) | BRPI0818581A2 (enExample) |
| CA (1) | CA2702467C (enExample) |
| CY (1) | CY1112083T1 (enExample) |
| DK (1) | DK2212283T3 (enExample) |
| ES (1) | ES2372332T3 (enExample) |
| HR (1) | HRP20110762T1 (enExample) |
| IL (1) | IL205001A (enExample) |
| MA (1) | MA31858B1 (enExample) |
| MX (1) | MX2010003949A (enExample) |
| MY (1) | MY151348A (enExample) |
| NZ (1) | NZ584690A (enExample) |
| PL (1) | PL2212283T3 (enExample) |
| PT (1) | PT2212283E (enExample) |
| RS (1) | RS52235B (enExample) |
| RU (1) | RU2477720C2 (enExample) |
| SI (1) | SI2212283T1 (enExample) |
| WO (1) | WO2009052062A1 (enExample) |
| ZA (1) | ZA201002115B (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5377504B2 (ja) | 2007-10-17 | 2013-12-25 | サノフイ | 置換されたｎ−フェニル−ピロリジニルメチルピロリジンアミドおよびその治療的用途 |
| PL2215058T3 (pl) | 2007-10-17 | 2012-04-30 | Sanofi Sa | Podstawione N-fenylo-bipirolidynomoczniki oraz ich zastosowanie terapeutyczne |
| RU2477720C2 (ru) * | 2007-10-17 | 2013-03-20 | Санофи-Авентис | Замещенные n-фенилбипирролидинкарбоксамиды и их применение в лечебных целях |
| HRP20110953T1 (hr) | 2007-10-17 | 2012-01-31 | Sanofi | Supstituirani n-fenilbipirolidinkarboksamidi i njihova upotreba u terapiji |
| AR074466A1 (es) | 2008-12-05 | 2011-01-19 | Sanofi Aventis | Piperidina espiro pirrolidinona y piperidinona sustituidas y su uso terapeutico en enfermedades mediadas por la modulacion de los receptores h3. |
| AR074467A1 (es) | 2008-12-05 | 2011-01-19 | Sanofi Aventis | Tetrahidropiran espiro pirrolidinonas y piperidinonas sustituidas, composiciones farmaceuticas que las contienen y uso de las mismas en el tratamiento y/o prevencion de enfermedades del snc ,tales como alzheimer y parkinson, entre otras. |
| SA110310332B1 (ar) * | 2009-05-01 | 2013-12-10 | Astrazeneca Ab | مركبات ميثانون (3 استبدال -ازيتيدين -1-يل )(5- فينيل -1، 3، 4- أوكساديازول -2-يل ) |
| JP5766278B2 (ja) | 2010-05-11 | 2015-08-19 | サノフイ | 置換されたｎ−アルキルおよびｎ−アシルテトラヒドロ−イソキノリン誘導体、それらの製造および治療上の使用 |
| WO2011143163A1 (en) * | 2010-05-11 | 2011-11-17 | Sanofi | Substituted n-phenyl spirolactam bipyrrolidines, preparation and therapeutic use thereof |
| WO2011143148A1 (en) * | 2010-05-11 | 2011-11-17 | Sanofi | Substituted n-heteroaryl spirolactam bipyrrolidines, preparation and therapeutic use thereof |
| TW201206901A (en) * | 2010-05-11 | 2012-02-16 | Sanofi Aventis | Substituted N-heteroaryl bipyrrolidine carboxamides, preparation and therapeutic use thereof |
| JP5784110B2 (ja) * | 2010-05-11 | 2015-09-24 | サノフイ | 置換されたｎ−ヘテロアリールテトラヒドロ−イソキノリン誘導体、その製造及び治療上の使用 |
| TW201206939A (en) * | 2010-05-11 | 2012-02-16 | Sanofi Aventis | Substituted phenyl cycloalkyl pyrrolidine (piperidine) spirolactams and amides, preparation and therapeutic use thereof |
| TW201206910A (en) | 2010-05-11 | 2012-02-16 | Sanofi Aventis | Substituted N-heterocycloalkyl bipyrrolidinylphenyl amide derivatives, preparation and therapeutic use thereof |
| EA201291384A1 (ru) | 2010-07-06 | 2013-07-30 | Астразенека Аб | Терапевтические агенты 976 |
| UY34194A (es) | 2011-07-15 | 2013-02-28 | Astrazeneca Ab | ?(3-(4-(espiroheterocíclico)metil)fenoxi)azetidin-1-il)(5-(fenil)-1,3,4-oxadiazol-2-il)metanona en el tratamiento de la obesidad? |
| JP2013232564A (ja) * | 2012-04-27 | 2013-11-14 | National Institute Of Advanced Industrial & Technology | 半導体装置および半導体装置の製造方法 |
| CN108250128A (zh) * | 2012-09-27 | 2018-07-06 | 江苏先声药业有限公司 | 作为钾通道调节剂的化合物 |
| WO2014108337A1 (en) | 2013-01-10 | 2014-07-17 | Grünenthal GmbH | Pyrazolyl-based carboxamides i as crac channel inhibitors |
| WO2014108336A1 (en) | 2013-01-10 | 2014-07-17 | Grünenthal GmbH | Pyrazolyl-based carboxamides ii as crac channel inhibitors |
| EP3366683A1 (en) | 2017-02-28 | 2018-08-29 | Acousia Therapeutics GmbH | Cyclic amides, acteamides and ureas useful as potassium channel openers |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20020507A1 (es) * | 2000-10-17 | 2002-06-25 | Schering Corp | Compuestos no-imidazoles como antagonistas del receptor histamina h3 |
| JP2006505590A (ja) * | 2002-10-23 | 2006-02-16 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | ヒスタミンｈ３受容体調節物質としてのフェニルピペリジンおよびフェニルピロリジン |
| US7223788B2 (en) * | 2003-02-14 | 2007-05-29 | Sanofi-Aventis Deutschland Gmbh | Substituted N-aryl heterocycles, process for their preparation and their use as medicaments |
| DE10306250A1 (de) * | 2003-02-14 | 2004-09-09 | Aventis Pharma Deutschland Gmbh | Substituierte N-Arylheterozyklen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| CA2600757C (en) | 2005-03-17 | 2014-02-18 | Eli Lilly And Company | Pyrrolidine derivatives as histamine h3 receptor antagonists |
| EP1868991B1 (en) * | 2005-04-01 | 2014-07-30 | Eli Lilly And Company | Histamine h3 receptor agents, preparation and therapeutic uses |
| CA2613192C (en) * | 2005-07-01 | 2013-12-31 | Eli Lilly And Company | Histamine h3 receptor agents, preparation and therapeutic uses |
| TW200804274A (en) * | 2005-10-27 | 2008-01-16 | Ucb Sa | Compounds comprising a lactam or a lactam derivative moiety, processes for making them, and their uses |
| KR20080095877A (ko) * | 2006-02-15 | 2008-10-29 | 사노피-아벤티스 | 아자사이클릴-치환된 아릴디하이드로이소퀴놀리논, 이의 제조 방법 및 약제로서 이의 용도 |
| RU2477720C2 (ru) * | 2007-10-17 | 2013-03-20 | Санофи-Авентис | Замещенные n-фенилбипирролидинкарбоксамиды и их применение в лечебных целях |
| HRP20110953T1 (hr) * | 2007-10-17 | 2012-01-31 | Sanofi | Supstituirani n-fenilbipirolidinkarboksamidi i njihova upotreba u terapiji |
| JP5377504B2 (ja) | 2007-10-17 | 2013-12-25 | サノフイ | 置換されたｎ−フェニル−ピロリジニルメチルピロリジンアミドおよびその治療的用途 |
| PL2215058T3 (pl) | 2007-10-17 | 2012-04-30 | Sanofi Sa | Podstawione N-fenylo-bipirolidynomoczniki oraz ich zastosowanie terapeutyczne |
-
2008
- 2008-10-14 RU RU2010119528/04A patent/RU2477720C2/ru not_active IP Right Cessation
- 2008-10-14 CN CN2008801212081A patent/CN101903340B/zh not_active Expired - Fee Related
- 2008-10-14 HR HR20110762T patent/HRP20110762T1/hr unknown
- 2008-10-14 AU AU2008312635A patent/AU2008312635B2/en not_active Ceased
- 2008-10-14 RS RS20110522A patent/RS52235B/sr unknown
- 2008-10-14 PT PT08839959T patent/PT2212283E/pt unknown
- 2008-10-14 SI SI200830416T patent/SI2212283T1/sl unknown
- 2008-10-14 JP JP2010530049A patent/JP5377503B2/ja not_active Expired - Fee Related
- 2008-10-14 EP EP08839959A patent/EP2212283B1/en active Active
- 2008-10-14 MX MX2010003949A patent/MX2010003949A/es active IP Right Grant
- 2008-10-14 NZ NZ584690A patent/NZ584690A/en not_active IP Right Cessation
- 2008-10-14 DK DK08839959.7T patent/DK2212283T3/da active
- 2008-10-14 MY MYPI20101299 patent/MY151348A/en unknown
- 2008-10-14 AT AT08839959T patent/ATE525351T1/de active
- 2008-10-14 WO PCT/US2008/079757 patent/WO2009052062A1/en not_active Ceased
- 2008-10-14 CA CA2702467A patent/CA2702467C/en not_active Expired - Fee Related
- 2008-10-14 PL PL08839959T patent/PL2212283T3/pl unknown
- 2008-10-14 KR KR1020107010769A patent/KR20100072077A/ko not_active Ceased
- 2008-10-14 ES ES08839959T patent/ES2372332T3/es active Active
- 2008-10-14 BR BRPI0818581-6A patent/BRPI0818581A2/pt not_active IP Right Cessation
-
2010
- 2010-03-15 US US12/724,028 patent/US8088808B2/en not_active Expired - Fee Related
- 2010-03-25 ZA ZA2010/02115A patent/ZA201002115B/en unknown
- 2010-04-11 IL IL205001A patent/IL205001A/en not_active IP Right Cessation
- 2010-05-17 MA MA32850A patent/MA31858B1/fr unknown
-
2011
- 2011-11-18 US US13/299,574 patent/US8252824B2/en not_active Expired - Fee Related
- 2011-11-24 CY CY20111101151T patent/CY1112083T1/el unknown
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