JP2011161225A5 - - Google Patents
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- Publication number
- JP2011161225A5 JP2011161225A5 JP2011015143A JP2011015143A JP2011161225A5 JP 2011161225 A5 JP2011161225 A5 JP 2011161225A5 JP 2011015143 A JP2011015143 A JP 2011015143A JP 2011015143 A JP2011015143 A JP 2011015143A JP 2011161225 A5 JP2011161225 A5 JP 2011161225A5
- Authority
- JP
- Japan
- Prior art keywords
- collagen
- implant
- mesenchymal stem
- cells
- umbilical cord
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000008186 Collagen Human genes 0.000 claims 9
- 108010035532 Collagen Proteins 0.000 claims 9
- 229920001436 collagen Polymers 0.000 claims 9
- 239000007943 implant Substances 0.000 claims 9
- 238000000034 method Methods 0.000 claims 8
- 210000002901 mesenchymal stem cell Anatomy 0.000 claims 7
- 210000004027 cell Anatomy 0.000 claims 5
- 102000046299 Transforming Growth Factor beta1 Human genes 0.000 claims 4
- 101800002279 Transforming growth factor beta-1 Proteins 0.000 claims 4
- 210000003954 umbilical cord Anatomy 0.000 claims 4
- 238000012258 culturing Methods 0.000 claims 3
- 102000012422 Collagen Type I Human genes 0.000 claims 2
- 108010022452 Collagen Type I Proteins 0.000 claims 2
- 102000000503 Collagen Type II Human genes 0.000 claims 2
- 108010041390 Collagen Type II Proteins 0.000 claims 2
- 229920002683 Glycosaminoglycan Polymers 0.000 claims 2
- 210000000577 adipose tissue Anatomy 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 210000001185 bone marrow Anatomy 0.000 claims 2
- 210000003074 dental pulp Anatomy 0.000 claims 2
- 230000004069 differentiation Effects 0.000 claims 2
- 210000004700 fetal blood Anatomy 0.000 claims 2
- 239000011159 matrix material Substances 0.000 claims 2
- 210000003205 muscle Anatomy 0.000 claims 2
- 210000002826 placenta Anatomy 0.000 claims 2
- 229940099456 transforming growth factor beta 1 Drugs 0.000 claims 2
- 239000002775 capsule Substances 0.000 claims 1
- 210000000845 cartilage Anatomy 0.000 claims 1
- 210000004489 deciduous teeth Anatomy 0.000 claims 1
- 230000007547 defect Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/700,469 | 2010-02-04 | ||
| US12/700,469 US8574614B2 (en) | 2010-02-04 | 2010-02-04 | Surgical grafts for repairing chondral defects |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015006164A Division JP2015091401A (ja) | 2010-02-04 | 2015-01-15 | 軟骨欠損の修復に用いる外科用グラフト |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011161225A JP2011161225A (ja) | 2011-08-25 |
| JP2011161225A5 true JP2011161225A5 (enExample) | 2014-04-10 |
| JP5764807B2 JP5764807B2 (ja) | 2015-08-19 |
Family
ID=44341891
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011015143A Active JP5764807B2 (ja) | 2010-02-04 | 2011-01-27 | 軟骨欠損の修復に用いる外科用グラフト |
| JP2015006164A Withdrawn JP2015091401A (ja) | 2010-02-04 | 2015-01-15 | 軟骨欠損の修復に用いる外科用グラフト |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015006164A Withdrawn JP2015091401A (ja) | 2010-02-04 | 2015-01-15 | 軟骨欠損の修復に用いる外科用グラフト |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8574614B2 (enExample) |
| EP (1) | EP2392358B1 (enExample) |
| JP (2) | JP5764807B2 (enExample) |
| CN (1) | CN102145195B (enExample) |
| ES (1) | ES2541486T3 (enExample) |
| PT (1) | PT2392358E (enExample) |
| SG (3) | SG173284A1 (enExample) |
| TW (1) | TWI469993B (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8883210B1 (en) | 2010-05-14 | 2014-11-11 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US10130736B1 (en) | 2010-05-14 | 2018-11-20 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US9352003B1 (en) | 2010-05-14 | 2016-05-31 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| AU2012335746B2 (en) | 2011-11-08 | 2017-04-27 | Auxocell Laboratories, Inc. | Systems and methods for processing cells |
| RU2494469C1 (ru) * | 2012-04-02 | 2013-09-27 | Федеральное государственное бюджетное учреждение "Новосибирский научно-исследовательский институт травматологии и ортопедии" Министерства здравоохранения и социального развития Российской Федерации (ФГБУ "ННИИТО" Минздравсоцразвития России) | Способ коррекции дефекта межпозвонкового диска в эксперименте |
| CN103387959A (zh) * | 2012-10-19 | 2013-11-13 | 夏佑红 | 一种乳牙干细胞及其制备方法和应用 |
| CN102899287B (zh) * | 2012-10-24 | 2013-08-21 | 天津和泽干细胞科技有限公司 | 一种诱导间充质干细胞向软骨细胞分化的方法及其在骨关节炎中的应用 |
| US20150037436A1 (en) | 2013-07-30 | 2015-02-05 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
| USD748462S1 (en) | 2014-08-11 | 2016-02-02 | Auxocell Laboratories, Inc. | Centrifuge clip |
| US9993748B2 (en) | 2014-08-11 | 2018-06-12 | Auxocell Laboratories, Inc. | Centrifuge clip and method |
| EP3297694A1 (en) | 2015-05-21 | 2018-03-28 | Musculoskeletal Transplant Foundation | Modified demineralized cortical bone fibers |
| US10912864B2 (en) | 2015-07-24 | 2021-02-09 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
| US11052175B2 (en) | 2015-08-19 | 2021-07-06 | Musculoskeletal Transplant Foundation | Cartilage-derived implants and methods of making and using same |
| CN111821518B (zh) * | 2019-04-15 | 2023-01-10 | 弗元(上海)生物科技有限公司 | 一种具有再生能力的组织工程骨的制备方法 |
| CN111821519A (zh) * | 2019-04-15 | 2020-10-27 | 弗元(上海)生物科技有限公司 | 一种组织工程软骨的制备方法及其应用 |
| CN115845142B (zh) * | 2022-12-23 | 2024-08-13 | 武汉大学 | 快速修复颌骨缺损的软骨样微组织的制备方法 |
| CN116983478A (zh) * | 2023-07-31 | 2023-11-03 | 江苏博赛孚医疗科技有限公司 | 有机物包埋的聚羟基乙酸软骨支架及其制备方法和应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5226914A (en) * | 1990-11-16 | 1993-07-13 | Caplan Arnold I | Method for treating connective tissue disorders |
| AU742638B2 (en) * | 1996-12-06 | 2002-01-10 | Mesoblast International Sarl | Improved chondrogenic differentiation of human mesenchymal stem cells |
| ATE220564T1 (de) | 1997-08-14 | 2002-08-15 | Sulzer Innotec Ag | Zusammensetzung und vorrichtung zur reparatur von knorpelgewebe in vivo bestehend aus nanokapseln mit osteoinduktiven und/oder chondroinduktiven faktoren |
| US6197586B1 (en) * | 1997-12-12 | 2001-03-06 | The Regents Of The University Of California | Chondrocyte-like cells useful for tissue engineering and methods |
| DE20019809U1 (de) | 2000-05-31 | 2001-07-12 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., 80636 München | Knorpelersatz und Biomatrix zur Kultivierung von Zellen |
| US20030050709A1 (en) * | 2001-02-23 | 2003-03-13 | Ulrich Noth | Trabecular bone-derived human mesenchymal stem cells |
| KR100494265B1 (ko) * | 2001-08-14 | 2005-06-13 | 메디포스트(주) | 관절연골손상 치료용 조성물 |
| US20040258731A1 (en) * | 2001-11-21 | 2004-12-23 | Tsuyoshi Shimoboji | Preparation approriate for cartilage tissue formation |
| ES2245879B1 (es) * | 2004-05-21 | 2006-12-16 | Universidad De Malaga | Composicion para la reparacion osea o cartilaginosa. |
| CN100477971C (zh) * | 2005-05-27 | 2009-04-15 | 中国人民解放军总医院 | 一种关节软骨原性微载体 |
-
2010
- 2010-02-04 US US12/700,469 patent/US8574614B2/en active Active
- 2010-06-11 TW TW99119088A patent/TWI469993B/zh active
-
2011
- 2011-01-24 SG SG2011004793A patent/SG173284A1/en unknown
- 2011-01-24 SG SG2013037825A patent/SG190660A1/en unknown
- 2011-01-24 SG SG10201402811YA patent/SG10201402811YA/en unknown
- 2011-01-27 JP JP2011015143A patent/JP5764807B2/ja active Active
- 2011-01-30 CN CN201110034680.5A patent/CN102145195B/zh active Active
- 2011-02-01 PT PT111529426T patent/PT2392358E/pt unknown
- 2011-02-01 EP EP11152942.6A patent/EP2392358B1/en active Active
- 2011-02-01 ES ES11152942.6T patent/ES2541486T3/es active Active
-
2015
- 2015-01-15 JP JP2015006164A patent/JP2015091401A/ja not_active Withdrawn
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