JP2011046710A - カルシトニン遺伝子関連ペプチドに対するアンタゴニスト抗体を投与することによって内臓痛を治療するための方法 - Google Patents

カルシトニン遺伝子関連ペプチドに対するアンタゴニスト抗体を投与することによって内臓痛を治療するための方法 Download PDF

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JP2011046710A
JP2011046710A JP2010190737A JP2010190737A JP2011046710A JP 2011046710 A JP2011046710 A JP 2011046710A JP 2010190737 A JP2010190737 A JP 2010190737A JP 2010190737 A JP2010190737 A JP 2010190737A JP 2011046710 A JP2011046710 A JP 2011046710A
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antibody
cgrp
seq
visceral pain
cdr
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Ariel Ates Pios
アテス ピオス アリエル
Kristian Todd Poulsen
トッド ポールセン クリスチャン
David Louis Shelton
ルイス シェルトン デイヴィッド
Joerg Zeller
ゼラー ジョーグ
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Rinat Neuroscience Corp
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Rinat Neuroscience Corp
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K2317/00—Immunoglobulins specific features
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JP2010190737A 2009-08-28 2010-08-27 カルシトニン遺伝子関連ペプチドに対するアンタゴニスト抗体を投与することによって内臓痛を治療するための方法 Pending JP2011046710A (ja)

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JP2015158079A Division JP2015193670A (ja) 2009-08-28 2015-08-10 カルシトニン遺伝子関連ペプチドに対するアンタゴニスト抗体を投与することによって内臓痛を治療するための方法

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JP2010190737A Pending JP2011046710A (ja) 2009-08-28 2010-08-27 カルシトニン遺伝子関連ペプチドに対するアンタゴニスト抗体を投与することによって内臓痛を治療するための方法
JP2015158079A Pending JP2015193670A (ja) 2009-08-28 2015-08-10 カルシトニン遺伝子関連ペプチドに対するアンタゴニスト抗体を投与することによって内臓痛を治療するための方法
JP2017152264A Withdrawn JP2018024661A (ja) 2009-08-28 2017-08-07 カルシトニン遺伝子関連ペプチドに対するアンタゴニスト抗体を投与することによって内臓痛を治療するための方法
JP2019090713A Pending JP2019163291A (ja) 2009-08-28 2019-05-13 カルシトニン遺伝子関連ペプチドに対するアンタゴニスト抗体を投与することによって内臓痛を治療するための方法
JP2021103124A Pending JP2021152058A (ja) 2009-08-28 2021-06-22 カルシトニン遺伝子関連ペプチドに対するアンタゴニスト抗体を投与することによって内臓痛を治療するための方法

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JP2017152264A Withdrawn JP2018024661A (ja) 2009-08-28 2017-08-07 カルシトニン遺伝子関連ペプチドに対するアンタゴニスト抗体を投与することによって内臓痛を治療するための方法
JP2019090713A Pending JP2019163291A (ja) 2009-08-28 2019-05-13 カルシトニン遺伝子関連ペプチドに対するアンタゴニスト抗体を投与することによって内臓痛を治療するための方法
JP2021103124A Pending JP2021152058A (ja) 2009-08-28 2021-06-22 カルシトニン遺伝子関連ペプチドに対するアンタゴニスト抗体を投与することによって内臓痛を治療するための方法

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US (6) US8623366B2 (https=)
EP (2) EP3165236B1 (https=)
JP (5) JP2011046710A (https=)
KR (1) KR101519192B1 (https=)
CN (2) CN107441487B (https=)
AU (1) AU2010288194B2 (https=)
BR (1) BR112012004464B8 (https=)
CA (1) CA2771186C (https=)
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Cited By (8)

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JP2014517699A (ja) * 2011-05-20 2014-07-24 アルダーバイオ・ホールディングズ・エルエルシー 抗ｃｇｒｐ組成物およびその使用
JP2017510579A (ja) * 2014-03-21 2017-04-13 テバ・ファーマシューティカルズ・インターナショナル・ゲーエムベーハーＴｅｖａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｔｅｒｎａｔｉｏｎａｌ ＧｍｂＨ カルシトニン遺伝子関連ペプチドに対するアンタゴニスト抗体及びその使用方法
US9708393B2 (en) 2011-05-20 2017-07-18 Alderbio Holdings Llc Use of anti-CGRP antibodies and antibody fragments to prevent or inhibit photophobia or light aversion in subjects in need thereof, especially migraine sufferers
US9855332B2 (en) 2011-05-20 2018-01-02 Alderbio Holdings Llc Use of anti-CGRP antibodies and antibody fragments to treat diarrhea in subjects with diseases or treatments that result in elevated CGRP levels
US11028160B2 (en) 2016-09-23 2021-06-08 Teva Pharmaceuticals International Gmbh Treating refractory migraine
US11639380B2 (en) 2019-01-08 2023-05-02 H. Lundbeck A/S Acute treatment and rapid treatment of headache using anti-CGRP antibodies
US12122821B2 (en) 2013-07-03 2024-10-22 H. Lundbeck A/S Regulation of glucose metabolism using anti-CGRP antibodies
US12384837B2 (en) 2020-04-06 2025-08-12 H. Lundbeck A/S Treatment of most bothersome symptom (MBS) associated with migraine using anti-CGRP antibodies

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US10556945B2 (en) 2014-03-21 2020-02-11 Teva Pharmaceuticals International Gmbh Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
WO2016044224A1 (en) 2014-09-15 2016-03-24 Amgen Inc. Bi-specific anti-cgrp receptor/pac1 receptor antigen binding proteins and uses thereof
TWI799849B (zh) 2015-04-24 2023-04-21 美商安美基公司 治療或預防偏頭痛之方法
EP3426288A4 (en) 2016-04-15 2019-10-30 Alder Biopharmaceuticals, Inc. ANTI-PACAP ANTIBODIES AND USES THEREOF
AU2019246983B2 (en) 2018-04-02 2025-12-18 Amgen Inc. Erenumab compositions and uses thereof
US10899826B1 (en) 2018-09-13 2021-01-26 Teva Pharmaceuticals International Gmbh Pharmaceutical compositions for an anti-CGRP antagonist antibody
JP7642542B2 (ja) * 2018-12-18 2025-03-10 ベーリンガー・インゲルハイム・イオ・カナダ・インコーポレイテッド Ｆｌｔ３アゴニスト抗体及びその使用
JP2022100917A (ja) * 2020-12-24 2022-07-06 株式会社LA Solutions 無痛分娩のための陣痛評価システム

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