JP2011032286A5 - - Google Patents
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- Publication number
- JP2011032286A5 JP2011032286A5 JP2010252426A JP2010252426A JP2011032286A5 JP 2011032286 A5 JP2011032286 A5 JP 2011032286A5 JP 2010252426 A JP2010252426 A JP 2010252426A JP 2010252426 A JP2010252426 A JP 2010252426A JP 2011032286 A5 JP2011032286 A5 JP 2011032286A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide compound
- amino acids
- terminus
- array
- carrier
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims description 16
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 14
- 150000001413 amino acids Chemical class 0.000 claims description 13
- 102100026142 Matrix extracellular phosphoglycoprotein Human genes 0.000 claims description 4
- 101710184030 Matrix extracellular phosphoglycoprotein Proteins 0.000 claims description 4
- 238000009472 formulation Methods 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 230000008468 bone growth Effects 0.000 claims 2
- 239000007864 aqueous solution Substances 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000002324 mouth wash Substances 0.000 claims 1
- 239000006072 paste Substances 0.000 claims 1
- 239000002504 physiological saline solution Substances 0.000 claims 1
- 239000000606 toothpaste Substances 0.000 claims 1
- 229940034610 toothpaste Drugs 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 description 3
- 102000006495 integrins Human genes 0.000 description 2
- 108010044426 integrins Proteins 0.000 description 2
- 239000000178 monomer Substances 0.000 description 2
- 206010065687 Bone loss Diseases 0.000 description 1
- 102000005701 Calcium-Binding Proteins Human genes 0.000 description 1
- 108010045403 Calcium-Binding Proteins Proteins 0.000 description 1
- 229920002683 Glycosaminoglycan Polymers 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64103400A | 2000-08-16 | 2000-08-16 | |
| US09/812,485 US6911425B2 (en) | 2000-08-16 | 2001-03-19 | Integrin binding motif containing peptides and methods of treating skeletal diseases |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007128730A Division JP2007302673A (ja) | 2000-08-16 | 2007-05-15 | ペプチドを含むインテグリン結合モチーフと骨疾患の治療法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011032286A JP2011032286A (ja) | 2011-02-17 |
| JP2011032286A5 true JP2011032286A5 (https=) | 2012-04-05 |
Family
ID=27093672
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002519497A Expired - Fee Related JP4318246B2 (ja) | 2000-08-16 | 2001-08-14 | ペプチドを含むインテグリン結合モチーフと骨疾患の治療法 |
| JP2007128730A Withdrawn JP2007302673A (ja) | 2000-08-16 | 2007-05-15 | ペプチドを含むインテグリン結合モチーフと骨疾患の治療法 |
| JP2010252426A Pending JP2011032286A (ja) | 2000-08-16 | 2010-11-11 | ペプチドを含むインテグリン結合モチーフと骨疾患の治療法 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002519497A Expired - Fee Related JP4318246B2 (ja) | 2000-08-16 | 2001-08-14 | ペプチドを含むインテグリン結合モチーフと骨疾患の治療法 |
| JP2007128730A Withdrawn JP2007302673A (ja) | 2000-08-16 | 2007-05-15 | ペプチドを含むインテグリン結合モチーフと骨疾患の治療法 |
Country Status (11)
| Country | Link |
|---|---|
| US (5) | US6911425B2 (https=) |
| EP (1) | EP1309616B1 (https=) |
| JP (3) | JP4318246B2 (https=) |
| CN (1) | CN100488980C (https=) |
| AT (1) | ATE430165T1 (https=) |
| AU (2) | AU2001286491B2 (https=) |
| CA (1) | CA2418716A1 (https=) |
| DE (1) | DE60138552D1 (https=) |
| ES (1) | ES2324153T3 (https=) |
| MX (1) | MXPA03001394A (https=) |
| WO (1) | WO2002014360A1 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100359015C (zh) * | 1998-05-18 | 2008-01-02 | 伦敦大学专科学院 | 多肽激素磷酸盐沉着因子 |
| US6911425B2 (en) * | 2000-08-16 | 2005-06-28 | Acologix, Inc. | Integrin binding motif containing peptides and methods of treating skeletal diseases |
| JP4638653B2 (ja) * | 2000-08-16 | 2011-02-23 | アコロジックス インコーポレイテッド | 骨成長促進ペプチドを含む歯科用製品 |
| CN1889922B (zh) * | 2003-12-01 | 2010-11-24 | 阿尔拉食品公司 | 骨桥蛋白在牙用制剂中的用途 |
| US20060193916A1 (en) * | 2005-01-07 | 2006-08-31 | Acologix, Inc. | Formulations of peptides for periodontal and dental treatments |
| WO2007011610A2 (en) * | 2005-07-18 | 2007-01-25 | Acologix, Inc. | Protein formulation for promoting hard tissue formation |
| CN100366302C (zh) * | 2006-09-14 | 2008-02-06 | 清华大学 | 一种用于骨修复的矿化多肽材料及其制备方法 |
| WO2008091632A2 (en) | 2007-01-22 | 2008-07-31 | Acologix, Inc. | A peptide composition and a method of promoting cartilage formation |
| JP5519121B2 (ja) * | 2008-06-02 | 2014-06-11 | 学校法人東日本学園 | 新規ｒｇｄ含有ペプチドおよび象牙質再生剤、骨再生剤、歯周組織再生剤 |
| RU2016140440A (ru) * | 2010-06-01 | 2018-12-14 | Белле-Эйр Фрейгренсиз, Инк. | Способ и продукт для борьбы с запахом изо рта |
| RU2503458C1 (ru) * | 2012-08-27 | 2014-01-10 | Сергей Васильевич Чуйкин | Способ местного лечения и профилактики основных стоматологических заболеваний у детей с хронической почечной недостаточностью с применением жевательного фитосубстрата |
| JP6692676B2 (ja) * | 2016-04-12 | 2020-05-13 | 学校法人東日本学園 | ネフロネクチンを含むう蝕治療剤 |
| CN106943311A (zh) * | 2017-04-07 | 2017-07-14 | 缪来耿 | 一种用于预防和或治疗牙周炎的牙膏及其制备方法 |
| HRP20240905T1 (hr) | 2017-06-14 | 2024-10-25 | Orthotrophix, Inc. | Peptid tpx-100 za ublažavanje bolova u zglobovima koljena |
| US11963996B2 (en) | 2018-10-24 | 2024-04-23 | Orthotrophix, Inc. | Method of treating knee pain |
| CN109762069B (zh) * | 2018-11-05 | 2022-01-14 | 广州领晟医疗科技有限公司 | 一种融合蛋白、其药物组合物及用途 |
| JP2022502356A (ja) | 2018-12-04 | 2022-01-11 | オルソトロフィックス インコーポレイテッド | 変形性関節症の治療に使用するための製剤 |
| CN111358935B (zh) * | 2020-02-27 | 2023-06-27 | 广州领晟医疗科技有限公司 | 多肽在制备抗肿瘤和/或抑制肿瘤转移药物中的用途及药物 |
| CN111249446B (zh) * | 2020-02-27 | 2023-06-27 | 广州领晟医疗科技有限公司 | 多肽及其盐的新用途 |
| CN111265652B (zh) * | 2020-02-27 | 2023-06-27 | 广州领晟医疗科技有限公司 | 多肽在制备治疗缺血性脑血管疾病的药物中的应用 |
| CN111569046B (zh) * | 2020-04-14 | 2023-06-27 | 广州领晟医疗科技有限公司 | 多肽在制备治疗胰腺炎药物中的用途及含有其的药物 |
| US11793857B2 (en) | 2020-10-01 | 2023-10-24 | Orthotrophix, Inc. | Hard tissue therapeutics |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5015628A (en) | 1986-06-12 | 1991-05-14 | The University Of Melbourne | Anticariogenic phosphopeptides |
| US5120829A (en) * | 1989-03-20 | 1992-06-09 | La Jolla Cancer Research Foundation | Hydrophobic attachment site for adhesion peptides |
| JPH0474132A (ja) * | 1990-07-13 | 1992-03-09 | Lion Corp | 歯根膜ならびに歯槽骨組織再生修復促進剤 |
| GB9203958D0 (en) | 1992-02-25 | 1992-04-08 | Norske Stats Oljeselskap | Catalytic multi-phase reactor |
| US5981478A (en) | 1993-11-24 | 1999-11-09 | La Jolla Cancer Research Foundation | Integrin-binding peptides |
| US6103709A (en) | 1993-12-23 | 2000-08-15 | The Regents Of The University Of California | Therapeutically effective 1α,25-dihydroxyvitamin D3 analogs and methods for treatment of vitamin D diseases |
| US5770565A (en) * | 1994-04-13 | 1998-06-23 | La Jolla Cancer Research Center | Peptides for reducing or inhibiting bone resorption |
| US6027592A (en) | 1995-06-06 | 2000-02-22 | Gillette Canada Inc. | Dental floss |
| US6300062B1 (en) | 1995-07-13 | 2001-10-09 | Biora Ab | Enamel matrix related polypeptide |
| US5837674A (en) | 1996-07-03 | 1998-11-17 | Big Bear Bio, Inc. | Phosphopeptides and methods of treating bone diseases |
| WO1999008730A1 (en) | 1997-08-15 | 1999-02-25 | Children's Medical Center Corporation | Osteopontin coated surfaces and methods of use |
| US6146655A (en) | 1997-08-29 | 2000-11-14 | Softy-Flex Inc. | Flexible intra-oral bandage and drug delivery system |
| US6410248B1 (en) | 1998-01-30 | 2002-06-25 | Massachusetts Institute Of Technology | General strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites |
| WO1999043844A1 (en) * | 1998-02-27 | 1999-09-02 | The Trustees Of Columbia University In The City Of New York | Reciprocal subtraction differential display |
| US6673900B2 (en) * | 1999-11-04 | 2004-01-06 | University College London | Polypeptide hormone-phosphatonin |
| CN100359015C (zh) | 1998-05-18 | 2008-01-02 | 伦敦大学专科学院 | 多肽激素磷酸盐沉着因子 |
| US6045780A (en) | 1998-06-22 | 2000-04-04 | Shemberg Marketing Corporation | Toothpaste composition |
| AUPP893999A0 (en) * | 1999-03-01 | 1999-03-25 | Csl Limited | Synthetic peptides containing protective epitopes for the treatment and prevention of periodontitis associated with porphyromonas gingivalis |
| US6145655A (en) * | 1999-10-04 | 2000-11-14 | Tsai; Allan | Lens cleaning kit |
| EP1130098A3 (en) | 2000-02-29 | 2003-09-10 | Pfizer Products Inc. | Mammalian osteoregulins |
| US20020102641A1 (en) | 2000-03-24 | 2002-08-01 | Susan Schia Vi | Oncogenic osteomalacia-related gene 1 |
| ATE254925T1 (de) | 2000-07-19 | 2003-12-15 | Univ Texas | Stimulierung des knochenwachstums mit peptidderivaten von thrombin |
| JP4638653B2 (ja) * | 2000-08-16 | 2011-02-23 | アコロジックス インコーポレイテッド | 骨成長促進ペプチドを含む歯科用製品 |
| US6911425B2 (en) * | 2000-08-16 | 2005-06-28 | Acologix, Inc. | Integrin binding motif containing peptides and methods of treating skeletal diseases |
-
2001
- 2001-03-19 US US09/812,485 patent/US6911425B2/en not_active Expired - Lifetime
- 2001-08-14 AU AU2001286491A patent/AU2001286491B2/en not_active Ceased
- 2001-08-14 DE DE60138552T patent/DE60138552D1/de not_active Expired - Lifetime
- 2001-08-14 WO PCT/US2001/025542 patent/WO2002014360A1/en not_active Ceased
- 2001-08-14 CN CNB018157939A patent/CN100488980C/zh not_active Expired - Fee Related
- 2001-08-14 MX MXPA03001394A patent/MXPA03001394A/es active IP Right Grant
- 2001-08-14 ES ES01965941T patent/ES2324153T3/es not_active Expired - Lifetime
- 2001-08-14 AU AU8649101A patent/AU8649101A/xx active Pending
- 2001-08-14 AT AT01965941T patent/ATE430165T1/de not_active IP Right Cessation
- 2001-08-14 JP JP2002519497A patent/JP4318246B2/ja not_active Expired - Fee Related
- 2001-08-14 EP EP01965941A patent/EP1309616B1/en not_active Expired - Lifetime
- 2001-08-14 CA CA002418716A patent/CA2418716A1/en not_active Abandoned
-
2005
- 2005-01-24 US US11/042,492 patent/US7160862B2/en not_active Expired - Lifetime
-
2006
- 2006-09-13 US US11/531,583 patent/US20070014742A1/en not_active Abandoned
-
2007
- 2007-05-15 JP JP2007128730A patent/JP2007302673A/ja not_active Withdrawn
- 2007-10-26 US US11/925,411 patent/US20090042791A1/en not_active Abandoned
-
2008
- 2008-07-03 US US12/167,491 patent/US20090062201A1/en not_active Abandoned
-
2010
- 2010-11-11 JP JP2010252426A patent/JP2011032286A/ja active Pending
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