JP2010538623A5 - - Google Patents
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- Publication number
- JP2010538623A5 JP2010538623A5 JP2010524397A JP2010524397A JP2010538623A5 JP 2010538623 A5 JP2010538623 A5 JP 2010538623A5 JP 2010524397 A JP2010524397 A JP 2010524397A JP 2010524397 A JP2010524397 A JP 2010524397A JP 2010538623 A5 JP2010538623 A5 JP 2010538623A5
- Authority
- JP
- Japan
- Prior art keywords
- igg
- sample
- binding
- endos polypeptide
- endos
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 claims 22
- 102000004196 processed proteins & peptides Human genes 0.000 claims 22
- 108090000765 processed proteins & peptides Proteins 0.000 claims 22
- 238000000034 method Methods 0.000 claims 20
- 230000027455 binding Effects 0.000 claims 12
- 102000014914 Carrier Proteins Human genes 0.000 claims 10
- 108091008324 binding proteins Proteins 0.000 claims 10
- 102000001706 Immunoglobulin Fab Fragments Human genes 0.000 claims 6
- 108010054477 Immunoglobulin Fab Fragments Proteins 0.000 claims 6
- 102000018071 Immunoglobulin Fc Fragments Human genes 0.000 claims 6
- 108010091135 Immunoglobulin Fc Fragments Proteins 0.000 claims 6
- 210000004027 cell Anatomy 0.000 claims 6
- 239000003153 chemical reaction reagent Substances 0.000 claims 5
- 230000015572 biosynthetic process Effects 0.000 claims 4
- 239000002122 magnetic nanoparticle Substances 0.000 claims 4
- 102000005744 Glycoside Hydrolases Human genes 0.000 claims 3
- 108010031186 Glycoside Hydrolases Proteins 0.000 claims 3
- 102000009490 IgG Receptors Human genes 0.000 claims 3
- 108010073807 IgG Receptors Proteins 0.000 claims 3
- 230000000694 effects Effects 0.000 claims 3
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 230000013595 glycosylation Effects 0.000 claims 2
- 238000006206 glycosylation reaction Methods 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 108010055837 phosphocarrier protein HPr Proteins 0.000 claims 2
- 238000000926 separation method Methods 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 101710120037 Toxin CcdB Proteins 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 239000006143 cell culture medium Substances 0.000 claims 1
- 125000003147 glycosyl group Chemical group 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000007885 magnetic separation Methods 0.000 claims 1
- 210000001616 monocyte Anatomy 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96008707P | 2007-09-14 | 2007-09-14 | |
| US60/960,087 | 2007-09-14 | ||
| PCT/EP2008/007457 WO2009033670A2 (en) | 2007-09-14 | 2008-09-11 | Method and kits for dissociating fcgamma-receptor-igg complexes and for igg purification and detection |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010538623A JP2010538623A (ja) | 2010-12-16 |
| JP2010538623A5 true JP2010538623A5 (enExample) | 2011-10-27 |
| JP5722627B2 JP5722627B2 (ja) | 2015-05-27 |
Family
ID=40076765
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010524397A Expired - Fee Related JP5722627B2 (ja) | 2007-09-14 | 2008-09-11 | ＦＣガンマ受容体−ＩｇＧ複合体の解離、ならびにＩｇＧの精製および検出のための方法およびキット |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8323908B2 (enExample) |
| EP (1) | EP2190984B1 (enExample) |
| JP (1) | JP5722627B2 (enExample) |
| CN (2) | CN102584989B (enExample) |
| DK (1) | DK2190984T3 (enExample) |
| PL (1) | PL2190984T3 (enExample) |
| WO (1) | WO2009033670A2 (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002216863B8 (en) * | 2000-12-21 | 2008-03-20 | Id Biomedical Corporation | Streptococcus pyogenes antigens and corresponding DNA fragments |
| US20120196310A1 (en) | 2009-10-02 | 2012-08-02 | Christiane Jaeger | A-fucosylation detection in antibodies |
| WO2011059385A1 (en) * | 2009-11-13 | 2011-05-19 | Bengt Guss | Immunizing composition for reducing streptococcal infections |
| WO2011149419A1 (en) | 2010-05-26 | 2011-12-01 | Intervacc Ab | Vaccine against streptococcal infections based on recombinant proteins |
| GB201103780D0 (en) * | 2011-03-04 | 2011-04-20 | Hansa Medical Ab | Treatment for ige-mediated disease |
| GB201115841D0 (en) * | 2011-09-13 | 2011-10-26 | Genovis Ab | Protein and method |
| GB201201314D0 (en) * | 2012-01-26 | 2012-03-07 | Isis Innovation | Composition |
| IN2014DN06806A (enExample) * | 2012-02-10 | 2015-05-22 | Univ Maryland | |
| TW201404784A (zh) * | 2012-07-27 | 2014-02-01 | Univ Nat Chiao Tung | 純化蛋白質的方法 |
| PL2991683T3 (pl) | 2013-05-02 | 2020-03-31 | Glykos Finland Oy | Koniugaty glikoproteiny lub glikanu z toksycznym ładunkiem |
| EP3160513B1 (en) | 2014-06-30 | 2020-02-12 | Glykos Finland Oy | Saccharide derivative of a toxic payload and antibody conjugates thereof |
| GB201413240D0 (en) * | 2014-07-25 | 2014-09-10 | Hansa Medical Ab | Method |
| GB201416849D0 (en) * | 2014-09-24 | 2014-11-05 | Genovis Ab | Method |
| GB201502306D0 (en) | 2015-02-12 | 2015-04-01 | Hansa Medical Ab | Protein |
| GB201502305D0 (en) | 2015-02-12 | 2015-04-01 | Hansa Medical Ab | Protein |
| CN108026518B (zh) * | 2015-07-16 | 2022-09-06 | 第一三共株式会社 | 新型endos突变型酶 |
| CN105368808B (zh) * | 2015-11-30 | 2019-04-30 | 苏州康聚生物科技有限公司 | 一种IdeS蛋白酶、其制备方法及应用 |
| CN105368904A (zh) * | 2015-11-30 | 2016-03-02 | 苏州康聚生物科技有限公司 | 一种免疫球蛋白g片段的制备方法及应用 |
| AU2017214441B2 (en) | 2016-02-04 | 2021-08-19 | Genovis Ab | New Streptococcal proteases |
| AU2017360807B2 (en) * | 2016-11-18 | 2024-11-28 | Biocon Limited | Rapid and efficient de-glycosylation of glycoproteins |
| CN110031632A (zh) * | 2019-04-03 | 2019-07-19 | 中国医学科学院北京协和医院 | 一种反映IgG4相关性疾病的疾病活动性的生物标志物及其用途 |
| GB202002072D0 (en) * | 2020-02-14 | 2020-04-01 | Hansa Biopharma AB | immunoglobulin detection and associated therapies |
| GB202007431D0 (en) | 2020-05-19 | 2020-07-01 | Hansa Biopharma AB | Cysteine protease |
| CN111707835B (zh) * | 2020-07-01 | 2022-11-11 | 珠海丽珠试剂股份有限公司 | 用于检测IgG4的组合物、试剂盒、应用及检测方法 |
| CA3195177A1 (en) | 2020-10-07 | 2022-04-14 | Asklepios Biopharmaceutical, Inc. | Therapeutic adeno-associated virus delivery of fukutin related protein (fkrp) for treating dystroglycanopathy disorders including limb girdle 2i (lgmd2i) |
| WO2022221529A1 (en) | 2021-04-16 | 2022-10-20 | Asklepios Biopharmaceutical, Inc. | Rational polyploid aav virions that cross the blood brain barrier and elicit reduced humoral response |
| EP4079848A1 (en) | 2021-04-22 | 2022-10-26 | Genovis Ab | Immunoglobulin cleaving enzyme |
| WO2024057095A1 (en) | 2022-09-14 | 2024-03-21 | Genovis Ab | Mutant protease |
| CN115873833B (zh) * | 2022-11-08 | 2024-08-16 | 上海泰昶生物技术有限公司 | 生产免疫球蛋白g降解酶的工程菌株和工艺 |
| WO2025256977A1 (en) | 2024-06-13 | 2025-12-18 | Bayer Aktiengesellschaft | Novel igm and igg cleaving enzymes |
| WO2025256978A1 (en) | 2024-06-13 | 2025-12-18 | Bayer Aktiengesellschaft | Variants of igm and igg cleaving enzymes |
| GB202413764D0 (en) | 2024-09-18 | 2024-10-30 | Genovis Ab | Immunoglobulin proteases and their uses |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9002212D0 (sv) * | 1990-06-21 | 1990-06-21 | Hightech Receptor Ab | Igg binding protein |
| GB0130228D0 (en) * | 2001-12-18 | 2002-02-06 | Hansa Medica Ab | Protein |
-
2008
- 2008-09-11 DK DK08802018.5T patent/DK2190984T3/da active
- 2008-09-11 EP EP08802018.5A patent/EP2190984B1/en not_active Not-in-force
- 2008-09-11 CN CN201210020646.7A patent/CN102584989B/zh not_active Expired - Fee Related
- 2008-09-11 JP JP2010524397A patent/JP5722627B2/ja not_active Expired - Fee Related
- 2008-09-11 CN CN2008801155765A patent/CN101889082A/zh active Pending
- 2008-09-11 WO PCT/EP2008/007457 patent/WO2009033670A2/en not_active Ceased
- 2008-09-11 US US12/677,680 patent/US8323908B2/en not_active Expired - Fee Related
- 2008-09-11 PL PL08802018T patent/PL2190984T3/pl unknown
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