JP2010538255A5 - - Google Patents
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- Publication number
- JP2010538255A5 JP2010538255A5 JP2010522513A JP2010522513A JP2010538255A5 JP 2010538255 A5 JP2010538255 A5 JP 2010538255A5 JP 2010522513 A JP2010522513 A JP 2010522513A JP 2010522513 A JP2010522513 A JP 2010522513A JP 2010538255 A5 JP2010538255 A5 JP 2010538255A5
- Authority
- JP
- Japan
- Prior art keywords
- proton concentration
- volume
- environment
- cells
- electrolyte
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93569807P | 2007-08-27 | 2007-08-27 | |
| US60/935,698 | 2007-08-27 | ||
| US3925708P | 2008-03-25 | 2008-03-25 | |
| US61/039,257 | 2008-03-25 | ||
| PCT/IL2008/001159 WO2009027970A2 (en) | 2007-08-27 | 2008-08-26 | Ph gradients controlled by electrolysis, and their use in isoelectric focusing |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010538255A JP2010538255A (ja) | 2010-12-09 |
| JP2010538255A5 true JP2010538255A5 (https=) | 2011-09-29 |
| JP5702142B2 JP5702142B2 (ja) | 2015-04-15 |
Family
ID=40254551
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010522513A Expired - Fee Related JP5702142B2 (ja) | 2007-08-27 | 2008-08-26 | 電気分解により制御されるｐＨ勾配および等電点フォーカシングにおけるその使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9274082B2 (https=) |
| EP (2) | EP2193100B1 (https=) |
| JP (1) | JP5702142B2 (https=) |
| KR (1) | KR20100053672A (https=) |
| CN (2) | CN103134843B (https=) |
| AU (1) | AU2008293381B2 (https=) |
| CA (1) | CA2697649C (https=) |
| WO (1) | WO2009027970A2 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2008293381B2 (en) | 2007-08-27 | 2012-07-19 | Technion Research & Development Foundation Ltd. | pH gradients controlled by electrolysis, and their use in isoelectric focusing |
| US10107782B2 (en) * | 2008-01-25 | 2018-10-23 | ProteinSimple | Method to perform limited two dimensional separation of proteins and other biologicals |
| CN102472724B (zh) * | 2009-08-18 | 2014-08-13 | 工业研究与发展基金会有限公司 | 分离分子分析物的方法和装置 |
| EP2467709B1 (en) | 2009-08-18 | 2018-02-28 | Technion Research & Development Foundation Ltd. | Proton concentration topographies, methods and devices for producing the same |
| JP5950429B2 (ja) * | 2011-05-13 | 2016-07-13 | シャープ株式会社 | 電気泳動方法、及び電気泳動装置 |
| CN104024396A (zh) | 2011-11-04 | 2014-09-03 | 生物辐射实验室股份有限公司 | 采用pH的电子控制的亲和方法及组合物 |
| EP2773959B1 (en) * | 2011-11-04 | 2019-04-10 | Bio-Rad Laboratories, Inc. | Protein fractionation based on isoelectric focusing |
| US9766207B2 (en) | 2011-11-04 | 2017-09-19 | Bio-Rad Laboratories, Inc. | Affinity methods and compositions employing electronic control of pH |
| EP2773221B1 (en) | 2011-11-04 | 2019-01-09 | Bio-Rad Laboratories, Inc. | Simultaneous purification of cell components |
| CN102565171A (zh) * | 2012-01-05 | 2012-07-11 | 厦门大学 | 一种用于等电聚焦分离的微流控芯片 |
| EP2814597A4 (en) | 2012-02-15 | 2015-10-28 | Bio Rad Laboratories | ELECTRONIC CONTROL OF PH-VALUE AND ION STRENGTH |
| US9321012B2 (en) | 2012-04-04 | 2016-04-26 | Bio-Rad Laboratories, Inc. | Electronic protein fractionation |
| CN104034789A (zh) * | 2013-04-02 | 2014-09-10 | 上海交通大学 | 蛋白质等电聚焦电泳的装置 |
| CN106267304B (zh) * | 2015-06-09 | 2019-10-18 | 海南光宇生物科技有限公司 | 具有酸碱性的生物纤维素凝胶膜及由其制备的医用敷料 |
| CN106260992B (zh) * | 2015-06-09 | 2020-02-18 | 海南椰国食品有限公司 | 一种含有酸性椰果和/或碱性椰果的食品 |
| EP3653121A1 (en) * | 2018-11-14 | 2020-05-20 | Koninklijke Philips N.V. | Sensor unit, body fluid monitoring device and method for detecting an analyte |
| CN119470588A (zh) * | 2024-11-18 | 2025-02-18 | 中国科学院空天信息创新研究院 | 集成式多种重金属检测微传感器 |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1987001206A1 (en) * | 1985-08-21 | 1987-02-26 | William Rudolph Hargreaves | Methods and devices for separating, mixing, and detecting components in specific binding assays |
| US4670119A (en) * | 1985-10-25 | 1987-06-02 | Hurd Stanley M | Isoelectric focusing device and process |
| US4900414A (en) * | 1988-08-19 | 1990-02-13 | Drug Delivery Systems Inc. | Commercial separation system and method using electrokinetic techniques |
| US5160594A (en) | 1989-03-08 | 1992-11-03 | Board Of Regents Of The University Of Texas System | Apparatus and methods for isoelectric focusing of amphoteric substances incorporating ion selective membranes in electrode chambers |
| DE3929137C1 (https=) * | 1989-09-01 | 1991-02-28 | Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung Ev, 8000 Muenchen, De | |
| US5110434A (en) * | 1990-12-20 | 1992-05-05 | Bio-Rad Laboratories, Inc. | Use of zwitterions to mobilize isoelectrically focused ampholyte zones |
| US5646001A (en) * | 1991-03-25 | 1997-07-08 | Immunivest Corporation | Affinity-binding separation and release of one or more selected subset of biological entities from a mixed population thereof |
| GB2275974B (en) | 1993-03-10 | 1996-01-10 | Curty Payen Sa | Improvements in and relating to gaskets |
| US6129828A (en) * | 1996-09-06 | 2000-10-10 | Nanogen, Inc. | Apparatus and methods for active biological sample preparation |
| JPH0933479A (ja) * | 1995-07-18 | 1997-02-07 | Mizu Kk | センサカバー及びこれを用いた電解水生成装置 |
| US5993627A (en) * | 1997-06-24 | 1999-11-30 | Large Scale Biology Corporation | Automated system for two-dimensional electrophoresis |
| AU4546899A (en) * | 1998-06-05 | 1999-12-20 | Sarnoff Corporation | Apparatus for separating molecules |
| JP3113645B2 (ja) * | 1999-03-01 | 2000-12-04 | ファースト・オーシャン株式会社 | 電解水製造法 |
| AU4773400A (en) * | 1999-05-28 | 2000-12-18 | Leisamon (Israel), Ltd. | Methods and apparatus for nonlinear mobility electrophoresis separation |
| DE10047088C2 (de) | 2000-09-21 | 2002-10-17 | Gerhard Weber | Medium für analytische und präparative Elektrophorese |
| JP2002265494A (ja) | 2001-03-06 | 2002-09-18 | Tokuyama Corp | 混合物から高純度化された目的物を製造する方法 |
| CN1549924A (zh) * | 2001-07-16 | 2004-11-24 | �����ʸ���˹�ع�˾ | 通过等电点分析生物分子的缓冲液的阵列 |
| GB0121189D0 (en) * | 2001-08-31 | 2001-10-24 | Diagnoswiss Sa | Apparatus and method for separating an analyte |
| SE0203773D0 (sv) * | 2002-12-19 | 2002-12-19 | Capture Device Ab | Method and device for capturing charged molecules traveling in a flow stream |
| US7150813B2 (en) * | 2003-06-12 | 2006-12-19 | Palo Alto Research Center Incorporated | Isoelectric focusing (IEF) of proteins with sequential and oppositely directed traveling waves in gel electrophoresis |
| JP2007504215A (ja) | 2003-09-03 | 2007-03-01 | バイオフォームズ | 生体分子を急速に結晶化するための方法及び装置 |
| JP2006213932A (ja) | 2004-05-07 | 2006-08-17 | Honda Motor Co Ltd | 電解水生成用電極 |
| CN1258828C (zh) | 2004-02-13 | 2006-06-07 | 清华大学 | 一种质子交换膜燃料电池多元催化剂的制备方法 |
| US7238272B2 (en) * | 2004-02-27 | 2007-07-03 | Yoichi Sano | Production of electrolytic water |
| EP1776581B1 (en) * | 2004-07-19 | 2015-05-06 | ProteinSimple | Method for protein detection |
| US7749370B2 (en) * | 2005-02-03 | 2010-07-06 | Osao Sumita | Manufacturing method of oxidative water to be employed for sterilization |
| JP5129442B2 (ja) | 2005-02-08 | 2013-01-30 | エア・ウォーター株式会社 | 液体の帯電物質の濃度調節装置 |
| JP4856530B2 (ja) | 2005-12-21 | 2012-01-18 | ミドリ安全株式会社 | 電解水の有効塩素濃度調節方法、電解水のｐＨ調節方法および電解水生成装置。 |
| US20090008268A1 (en) | 2006-02-17 | 2009-01-08 | Peter Salathe | Process for Production of a Disinfectant Through the Electrochemical Activation (Eca) of Water, a Disinfectant Produced in this Way and the Use Thereof |
| WO2008112253A1 (en) | 2007-03-13 | 2008-09-18 | Siemens Water Technologies Corp. | Devices and methods for acid and base generation |
| US20110100821A1 (en) | 2007-04-20 | 2011-05-05 | Brian Furmanski | Mineral oil free isoelectric focusing apparatus for immobilized ph gradient strips |
| CN101294930B (zh) | 2007-04-27 | 2013-08-14 | 杨春 | 一种整体型固定化pH梯度的制备方法及其应用 |
| WO2009002459A2 (en) | 2007-06-22 | 2008-12-31 | Massachusetts Institute Of Technology | Free flow isoelectric focusing devices and methods |
| AU2008293381B2 (en) | 2007-08-27 | 2012-07-19 | Technion Research & Development Foundation Ltd. | pH gradients controlled by electrolysis, and their use in isoelectric focusing |
| CN102472724B (zh) * | 2009-08-18 | 2014-08-13 | 工业研究与发展基金会有限公司 | 分离分子分析物的方法和装置 |
| EP2467709B1 (en) * | 2009-08-18 | 2018-02-28 | Technion Research & Development Foundation Ltd. | Proton concentration topographies, methods and devices for producing the same |
| EP2773959B1 (en) * | 2011-11-04 | 2019-04-10 | Bio-Rad Laboratories, Inc. | Protein fractionation based on isoelectric focusing |
-
2008
- 2008-08-26 AU AU2008293381A patent/AU2008293381B2/en not_active Ceased
- 2008-08-26 CN CN201210450797.6A patent/CN103134843B/zh not_active Expired - Fee Related
- 2008-08-26 JP JP2010522513A patent/JP5702142B2/ja not_active Expired - Fee Related
- 2008-08-26 WO PCT/IL2008/001159 patent/WO2009027970A2/en not_active Ceased
- 2008-08-26 EP EP08789831.8A patent/EP2193100B1/en not_active Not-in-force
- 2008-08-26 KR KR1020107006740A patent/KR20100053672A/ko not_active Ceased
- 2008-08-26 CA CA2697649A patent/CA2697649C/en active Active
- 2008-08-26 EP EP12177368.3A patent/EP2559666B1/en not_active Not-in-force
- 2008-08-26 US US12/675,794 patent/US9274082B2/en active Active
- 2008-08-26 CN CN2008801146906A patent/CN101868425B/zh not_active Expired - Fee Related
-
2016
- 2016-02-28 US US15/055,601 patent/US10132776B2/en active Active
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