EP2814597A4 - Electronic control of ph and ionic strength - Google Patents

Electronic control of ph and ionic strength

Info

Publication number
EP2814597A4
EP2814597A4 EP13749830.9A EP13749830A EP2814597A4 EP 2814597 A4 EP2814597 A4 EP 2814597A4 EP 13749830 A EP13749830 A EP 13749830A EP 2814597 A4 EP2814597 A4 EP 2814597A4
Authority
EP
European Patent Office
Prior art keywords
electronic control
ionic strength
ionic
strength
electronic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP13749830.9A
Other languages
German (de)
French (fr)
Other versions
EP2814597A1 (en
Inventor
Aran Paulus
Camille Diges
Roumen Bogoev
Sricharan Bandhakavi
Annett Hahn-Windgassen
Anton Posch
Elad Brod
Uri Sivan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Technion Research and Development Foundation Ltd
Bio Rad Laboratories Inc
Original Assignee
Technion Research and Development Foundation Ltd
Bio Rad Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technion Research and Development Foundation Ltd, Bio Rad Laboratories Inc filed Critical Technion Research and Development Foundation Ltd
Publication of EP2814597A1 publication Critical patent/EP2814597A1/en
Publication of EP2814597A4 publication Critical patent/EP2814597A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D57/00—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C
    • B01D57/02—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C by electrophoresis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/42—Electrodialysis; Electro-osmosis ; Electro-ultrafiltration; Membrane capacitive deionization
    • B01D61/44—Ion-selective electrodialysis
    • B01D61/445—Ion-selective electrodialysis with bipolar membranes; Water splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/42—Electrodialysis; Electro-osmosis ; Electro-ultrafiltration; Membrane capacitive deionization
    • B01D61/44—Ion-selective electrodialysis
    • B01D61/46—Apparatus therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/42—Electrodialysis; Electro-osmosis ; Electro-ultrafiltration; Membrane capacitive deionization
    • B01D61/44—Ion-selective electrodialysis
    • B01D61/46—Apparatus therefor
    • B01D61/465—Apparatus therefor comprising the membrane sequence AB or BA, where B is a bipolar membrane
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/42—Electrodialysis; Electro-osmosis ; Electro-ultrafiltration; Membrane capacitive deionization
    • B01D61/44—Ion-selective electrodialysis
    • B01D61/46—Apparatus therefor
    • B01D61/50—Stacks of the plate-and-frame type
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B9/00—Cells or assemblies of cells; Constructional parts of cells; Assemblies of constructional parts, e.g. electrode-diaphragm assemblies; Process-related cell features
    • C25B9/17—Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof
    • C25B9/19—Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof with diaphragms
    • C25B9/23—Cells comprising dimensionally-stable non-movable electrodes; Assemblies of constructional parts thereof with diaphragms comprising ion-exchange membranes in or on which electrode material is embedded
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/18—Details relating to membrane separation process operations and control pH control
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/96—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation using ion-exchange
EP13749830.9A 2012-02-15 2013-02-15 Electronic control of ph and ionic strength Withdrawn EP2814597A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261599115P 2012-02-15 2012-02-15
US201261722612P 2012-11-05 2012-11-05
PCT/US2013/026485 WO2013123425A1 (en) 2012-02-15 2013-02-15 Electronic control of ph and ionic strength

Publications (2)

Publication Number Publication Date
EP2814597A1 EP2814597A1 (en) 2014-12-24
EP2814597A4 true EP2814597A4 (en) 2015-10-28

Family

ID=48984780

Family Applications (1)

Application Number Title Priority Date Filing Date
EP13749830.9A Withdrawn EP2814597A4 (en) 2012-02-15 2013-02-15 Electronic control of ph and ionic strength

Country Status (4)

Country Link
US (1) US9658195B2 (en)
EP (1) EP2814597A4 (en)
CN (1) CN104254390B (en)
WO (1) WO2013123425A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9321012B2 (en) * 2012-04-04 2016-04-26 Bio-Rad Laboratories, Inc. Electronic protein fractionation
CN104871357B (en) * 2012-09-09 2018-11-20 百奥堪引赛股份有限公司 Electrochemica biological reactor module and the method for using the module
EP3112869A1 (en) * 2015-06-30 2017-01-04 IMEC vzw Sensor device
CN105758890B (en) * 2016-02-03 2018-11-30 浙江恒达仪器仪表股份有限公司 A kind of precipitation on-line monitoring system and method
US20220268729A1 (en) * 2021-02-24 2022-08-25 Robert Bosch Gmbh Measuring ion strength using closed-loop electrochemical ph modulation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6027643A (en) * 1997-09-04 2000-02-22 Dionex Corporation Ion chromatographic method and apparatus using a combined suppressor and eluent generator
WO2004024302A1 (en) * 2002-09-11 2004-03-25 Dionex Corporation Electrolytic eluent generator and method of use
WO2004046351A1 (en) * 2002-11-19 2004-06-03 C-Tech Innovation Limited Control of biocatalysis reactions
DE102010017491A1 (en) * 2010-06-21 2011-12-22 WME Gesellschaft für windkraftbetriebene Meerwasserentsalzung mbH A process for producing hydrogen chloride or an aqueous solution thereof using a saline raw water, product produced therewith, use of the product and electrodialysis system

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4396477A (en) 1981-06-29 1983-08-02 Ionics, Incorporated Separation of proteins using electrodialysis-isoelectric focusing combination
CA1292092C (en) 1985-08-21 1991-11-12 Biotope, Inc. Methods and devices for separating and detecting components in specific binding assays
US4880513A (en) 1986-06-20 1989-11-14 The Graver Company Method and apparatus for generating acid and base regenerants and the use thereof to regenerate ion-exchange resins
ES2037273T3 (en) 1987-04-11 1993-06-16 Ciba-Geigy Ag ISOELECTRIC TARGETING PROCESS AND MEANS TO CARRY OUT SUCH PROCESS.
US4900414A (en) 1988-08-19 1990-02-13 Drug Delivery Systems Inc. Commercial separation system and method using electrokinetic techniques
US4936962A (en) 1989-03-01 1990-06-26 Fmc Corporation Process for adjusting the pH of an aqueous flowable fluid
US5160594A (en) 1989-03-08 1992-11-03 Board Of Regents Of The University Of Texas System Apparatus and methods for isoelectric focusing of amphoteric substances incorporating ion selective membranes in electrode chambers
US5045204A (en) 1990-02-13 1991-09-03 Dionex Corporation Method and apparatus for generating a high purity chromatography eluent
US5198086A (en) 1990-12-21 1993-03-30 Allied-Signal Electrodialysis of salts of weak acids and/or weak bases
US5078853A (en) 1991-03-22 1992-01-07 Assay Technology, Inc. Segmented electrophoretic separation system useful for lipid profiling
US5646001A (en) 1991-03-25 1997-07-08 Immunivest Corporation Affinity-binding separation and release of one or more selected subset of biological entities from a mixed population thereof
US5650055A (en) 1993-04-07 1997-07-22 Margolis; Joel Electrophoresis separation method and apparatus using barrier separation and polarity reversing
US5437774A (en) 1993-12-30 1995-08-01 Zymogenetics, Inc. High molecular weight electrodialysis
GB9425138D0 (en) 1994-12-12 1995-02-08 Dynal As Isolation of nucleic acid
US5567293A (en) 1994-12-22 1996-10-22 Pulp And Paper Research Institute Of Canada Electromembrane processes for the treatment of kraft mill electrostatic precipitator catch
DE19530132C2 (en) 1995-08-16 1998-07-16 Max Planck Gesellschaft Process for the purification, stabilization or isolation of nucleic acids from biological materials
AU7563296A (en) 1995-11-14 1997-06-05 Gunter Fuhr Device and process for adjusting ion concentrations
ZA981370B (en) * 1997-02-20 1998-09-07 Cerberus Developments Bv Method and apparatus for continuous flow isoelectric focusing for purifying biological substances
US5773645A (en) 1997-05-05 1998-06-30 Bio-Rad Laboratories, Inc. Two-dimensional electrophoresis device
WO1999026724A2 (en) 1997-11-25 1999-06-03 Mosaic Technologies Devices and methods for detecting target molecules in biological samples
US6225129B1 (en) 1998-02-02 2001-05-01 Dionex Corporation Large capacity acid or base generation apparatus and method of use
US6277258B1 (en) 1998-05-06 2001-08-21 Washington State University Research Foundation Device and method for focusing solutes in an electric field gradient
GB9811656D0 (en) 1998-05-29 1998-07-29 Oxford Glycosciences Uk Ltd Gels, methods and apparatus for identification and characterization of biomolecules
US20040242849A1 (en) 1998-06-02 2004-12-02 Gradipore Limited Purification of antibodies
US6699986B2 (en) 1998-08-04 2004-03-02 Ortho-Clinical Diagnostics, Inc. Electrophoretic separation of nucleic acids from proteins at low ph
US6077434A (en) * 1999-01-15 2000-06-20 Dionex Corporation Current-efficient suppressors and method of use
US6969614B1 (en) 1999-02-16 2005-11-29 The United States Of America As Represented By The Department Of Health And Human Services Methods for the isolation and analysis of cellular protein content
JP2003514829A (en) 1999-11-15 2003-04-22 プロテオム システムズ リミテッド Multi-chamber electrophoresis
US7077942B1 (en) 1999-12-23 2006-07-18 Gradipore Limited Removal of biological contaminants
US6638408B1 (en) * 2000-04-03 2003-10-28 The Wistar Institute Method and device for separation of charged molecules by solution isoelectric focusing
AUPQ691400A0 (en) 2000-04-14 2000-05-11 Life Therapeutics Limited Separation of micromolecules
AUPQ697300A0 (en) 2000-04-18 2000-05-11 Life Therapeutics Limited Separation apparatus
GB0010957D0 (en) 2000-05-05 2000-06-28 Novartis Ag Compound & method
FR2824144B1 (en) 2001-04-30 2004-09-17 Metagenex S A R L METHOD OF PRENATAL DIAGNOSIS ON FETAL CELLS ISOLATED FROM MATERNAL BLOOD
GB0121189D0 (en) 2001-08-31 2001-10-24 Diagnoswiss Sa Apparatus and method for separating an analyte
ATE403872T1 (en) 2001-12-08 2008-08-15 Micromass Ltd MASS SPECTORMETRY METHOD
US6655649B2 (en) 2002-03-11 2003-12-02 Bio-Rad Laboratories, Inc. Assembly for casting and use of an isoelectric focusing strip
US20030226752A1 (en) 2002-06-05 2003-12-11 Gradipore Limited Method for pH-biased isoelectric trapping separation
US8080145B2 (en) 2003-01-15 2011-12-20 Protasis Corporation Method and apparatus determining the isoelectric point of charged analyte
US7517696B2 (en) 2003-01-30 2009-04-14 Dionex Corporation Chemical suppressors and method of use
US7655477B1 (en) 2003-02-26 2010-02-02 Science Applications International Corporation System and method for the separation of analytes
JP2006520606A (en) 2003-03-19 2006-09-14 アルファ ワッサーマン インコーポレイテッド Separation and accumulation of intracellular components and proteins derived therefrom
WO2005021841A2 (en) 2003-09-03 2005-03-10 Bioforms Methods and apparatus for rapid crystallization of biomolecules
WO2005040782A1 (en) 2003-10-24 2005-05-06 The Texas A & M University System Electrophoresis apparatus
US7935479B2 (en) 2004-07-19 2011-05-03 Cell Biosciences, Inc. Methods and devices for analyte detection
EP1776581B1 (en) 2004-07-19 2015-05-06 ProteinSimple Method for protein detection
WO2006063625A1 (en) 2004-12-17 2006-06-22 Agilent Technologies, Inc. Fractionation using electro elution
KR100647328B1 (en) 2005-06-21 2006-11-23 삼성전자주식회사 A microfluidic device for electrically regulating the ph of a fluid therein and method for regulating the ph of a fluid in a microfuidic device using the same
DE602005027623D1 (en) 2005-11-02 2011-06-01 Agilent Technologies Inc POWER-SUPPORTED SAMPLING IN GEL ELECTROPHORESIS
EP2049233A4 (en) 2006-07-10 2011-08-31 Convergent Bioscience Ltd Method and apparatus for precise selection and extraction of a focused component in isoelectric focusing performed in micro-channels
JP5702142B2 (en) 2007-08-27 2015-04-15 テクニオン リサーチ アンド ディベロップメント ファウンデーションリミティド PH gradient controlled by electrolysis and its use in isoelectric focusing
US8475639B2 (en) 2007-12-06 2013-07-02 Dionex Corporation Titration device and method
WO2009133153A1 (en) 2008-04-29 2009-11-05 Becton, Dickinson And Company Methods and systems for the separation and analysis of analytes using ffe
US8623192B2 (en) 2008-10-20 2014-01-07 Stc.Unm High resolution focusing and separation of proteins in nanofluidic channels
EP2419449A1 (en) 2009-04-16 2012-02-22 Charité Universitätsmedizin Berlin B-lymphocyte targeting agents for use in a method for the treatment of a disease
CN102472724B (en) 2009-08-18 2014-08-13 工业研究与发展基金会有限公司 Methods and devices of separating molecular analytes
US9028664B2 (en) 2009-08-18 2015-05-12 Technion Research & Development Foundation Limited Proton concentration topographies, methods and devices for producing the same
CN102079781A (en) 2010-04-22 2011-06-01 中国疾病预防控制中心寄生虫病预防控制所 Immunogenic protein in schistosoma japonicum soluble egg antigen as well as screening method and application thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6027643A (en) * 1997-09-04 2000-02-22 Dionex Corporation Ion chromatographic method and apparatus using a combined suppressor and eluent generator
WO2004024302A1 (en) * 2002-09-11 2004-03-25 Dionex Corporation Electrolytic eluent generator and method of use
WO2004046351A1 (en) * 2002-11-19 2004-06-03 C-Tech Innovation Limited Control of biocatalysis reactions
DE102010017491A1 (en) * 2010-06-21 2011-12-22 WME Gesellschaft für windkraftbetriebene Meerwasserentsalzung mbH A process for producing hydrogen chloride or an aqueous solution thereof using a saline raw water, product produced therewith, use of the product and electrodialysis system

Also Published As

Publication number Publication date
CN104254390A (en) 2014-12-31
EP2814597A1 (en) 2014-12-24
US20130220830A1 (en) 2013-08-29
WO2013123425A1 (en) 2013-08-22
CN104254390B (en) 2017-05-10
US9658195B2 (en) 2017-05-23

Similar Documents

Publication Publication Date Title
GB2512428B (en) Vehicle and method of control thereof
GB2511899B (en) Vehicle and method of control thereof
GB2511604B (en) Vehicle and method of control thereof
GB201210282D0 (en) Vehicle and method of control thereof
EP2891049A4 (en) Methods and devices for terminal control
EP2890859A4 (en) Reduced mechanical energy well control systems and methods of use
EP3757746C0 (en) Terminal and method of operating the terminal
EP2849023A4 (en) Electronic device and control method therefor
GB2506485B (en) User terminal control system and method
EP2879035A4 (en) Screen control method and terminal
GB2508574B (en) Improvements in and relating to the control of ions
EP2814132A4 (en) Parallel accumulator system and method of control thereof
GB201212685D0 (en) Control of electronic devices
SG2013081724A (en) Sensor and method of controlling the same
GB2504831B (en) Vehicle and method of control thereof
HK1201575A1 (en) Aqueous assembly and control method
EP2914040A4 (en) Terminal and synchronization control method thereof
EP2654307A4 (en) Eyeglass device and control method of eyeglass device
EP2898157A4 (en) Building board and method of mounting
EP2827268A4 (en) Information terminal and execution control method
EP2665345A4 (en) Control circuit and control method
EP2814597A4 (en) Electronic control of ph and ionic strength
EP2675052A4 (en) Circuit and control method thereof
EP2850519A4 (en) Terminal device and method of controlling the same
GB2509246B (en) Component and method of formation thereof

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20140814

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

DAX Request for extension of the european patent (deleted)
RIN1 Information on inventor provided before grant (corrected)

Inventor name: BANDHAKAVI, SRICHARAN

Inventor name: SIVAN, URI

Inventor name: PAULUS, ARAN

Inventor name: HAHN-WINDGASSEN, ANNETT

Inventor name: DIGES, CAMILLE

Inventor name: BOGOEV, ROUMEN

Inventor name: POSCH, ANTON

Inventor name: BROD, ELAD

RA4 Supplementary search report drawn up and despatched (corrected)

Effective date: 20150924

RIC1 Information provided on ipc code assigned before grant

Ipc: B01D 61/46 20060101AFI20150918BHEP

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

17Q First examination report despatched

Effective date: 20171017

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

RAP3 Party data changed (applicant data changed or rights of an application transferred)

Owner name: BIO-RAD LABORATORIES, INC.

Owner name: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD.

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: EXAMINATION IS IN PROGRESS

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN WITHDRAWN

18W Application withdrawn

Effective date: 20220303