CN103134843B - 通过电解控制ph梯度以及它们在等电聚焦中的用途 - Google Patents
通过电解控制ph梯度以及它们在等电聚焦中的用途 Download PDFInfo
- Publication number
- CN103134843B CN103134843B CN201210450797.6A CN201210450797A CN103134843B CN 103134843 B CN103134843 B CN 103134843B CN 201210450797 A CN201210450797 A CN 201210450797A CN 103134843 B CN103134843 B CN 103134843B
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- proton concentration
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Classifications
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- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F1/00—Treatment of water, waste water, or sewage
- C02F1/46—Treatment of water, waste water, or sewage by electrochemical methods
- C02F1/461—Treatment of water, waste water, or sewage by electrochemical methods by electrolysis
- C02F1/46104—Devices therefor; Their operating or servicing
- C02F1/46109—Electrodes
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44795—Isoelectric focusing
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- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F1/00—Treatment of water, waste water, or sewage
- C02F1/66—Treatment of water, waste water, or sewage by neutralisation; pH adjustment
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
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- G—PHYSICS
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- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44743—Introducing samples
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- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F1/00—Treatment of water, waste water, or sewage
- C02F1/46—Treatment of water, waste water, or sewage by electrochemical methods
- C02F1/461—Treatment of water, waste water, or sewage by electrochemical methods by electrolysis
- C02F1/46104—Devices therefor; Their operating or servicing
- C02F1/4618—Devices therefor; Their operating or servicing for producing "ionised" acidic or basic water
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- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F1/00—Treatment of water, waste water, or sewage
- C02F1/46—Treatment of water, waste water, or sewage by electrochemical methods
- C02F1/461—Treatment of water, waste water, or sewage by electrochemical methods by electrolysis
- C02F1/46104—Devices therefor; Their operating or servicing
- C02F1/46109—Electrodes
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- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F2201/00—Apparatus for treatment of water, waste water or sewage
- C02F2201/46—Apparatus for electrochemical processes
- C02F2201/461—Electrolysis apparatus
- C02F2201/46105—Details relating to the electrolytic devices
- C02F2201/46115—Electrolytic cell with membranes or diaphragms
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- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F2201/00—Apparatus for treatment of water, waste water or sewage
- C02F2201/46—Apparatus for electrochemical processes
- C02F2201/461—Electrolysis apparatus
- C02F2201/46105—Details relating to the electrolytic devices
- C02F2201/4612—Controlling or monitoring
-
- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F2201/00—Apparatus for treatment of water, waste water or sewage
- C02F2201/46—Apparatus for electrochemical processes
- C02F2201/461—Electrolysis apparatus
- C02F2201/46105—Details relating to the electrolytic devices
- C02F2201/4612—Controlling or monitoring
- C02F2201/46125—Electrical variables
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- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F2201/00—Apparatus for treatment of water, waste water or sewage
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- C02F2201/4612—Controlling or monitoring
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- C—CHEMISTRY; METALLURGY
- C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
- C02F2209/00—Controlling or monitoring parameters in water treatment
- C02F2209/06—Controlling or monitoring parameters in water treatment pH
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Electrochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
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- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Water Supply & Treatment (AREA)
- Environmental & Geological Engineering (AREA)
- Engineering & Computer Science (AREA)
- Hydrology & Water Resources (AREA)
- General Chemical & Material Sciences (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93569807P | 2007-08-27 | 2007-08-27 | |
| US60/935698 | 2007-08-27 | ||
| US60/935,698 | 2007-08-27 | ||
| US3925708P | 2008-03-25 | 2008-03-25 | |
| US61/039,257 | 2008-03-25 | ||
| US61/039257 | 2008-03-25 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2008801146906A Division CN101868425B (zh) | 2007-08-27 | 2008-08-26 | 通过电解控制pH梯度以及它们在等电聚焦中的用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103134843A CN103134843A (zh) | 2013-06-05 |
| CN103134843B true CN103134843B (zh) | 2014-11-12 |
Family
ID=40254551
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210450797.6A Expired - Fee Related CN103134843B (zh) | 2007-08-27 | 2008-08-26 | 通过电解控制ph梯度以及它们在等电聚焦中的用途 |
| CN2008801146906A Expired - Fee Related CN101868425B (zh) | 2007-08-27 | 2008-08-26 | 通过电解控制pH梯度以及它们在等电聚焦中的用途 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2008801146906A Expired - Fee Related CN101868425B (zh) | 2007-08-27 | 2008-08-26 | 通过电解控制pH梯度以及它们在等电聚焦中的用途 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9274082B2 (https=) |
| EP (2) | EP2193100B1 (https=) |
| JP (1) | JP5702142B2 (https=) |
| KR (1) | KR20100053672A (https=) |
| CN (2) | CN103134843B (https=) |
| AU (1) | AU2008293381B2 (https=) |
| CA (1) | CA2697649C (https=) |
| WO (1) | WO2009027970A2 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009027970A2 (en) | 2007-08-27 | 2009-03-05 | Technion - Research & Development Foundation Ltd | Ph gradients controlled by electrolysis, and their use in isoelectric focusing |
| US10107782B2 (en) * | 2008-01-25 | 2018-10-23 | ProteinSimple | Method to perform limited two dimensional separation of proteins and other biologicals |
| EP2467709B1 (en) | 2009-08-18 | 2018-02-28 | Technion Research & Development Foundation Ltd. | Proton concentration topographies, methods and devices for producing the same |
| WO2011021195A1 (en) | 2009-08-18 | 2011-02-24 | Technion Research & Development Foundation Ltd. | Methods and devices of separating molecular analytes |
| JP5950429B2 (ja) * | 2011-05-13 | 2016-07-13 | シャープ株式会社 | 電気泳動方法、及び電気泳動装置 |
| US9234875B2 (en) | 2011-11-04 | 2016-01-12 | Bio-Rad Laboratories, Inc. | Simultaneous purification of cell components |
| US9766207B2 (en) | 2011-11-04 | 2017-09-19 | Bio-Rad Laboratories, Inc. | Affinity methods and compositions employing electronic control of pH |
| WO2013067529A1 (en) | 2011-11-04 | 2013-05-10 | Bio-Rad Laboratories, Inc. | PROTEIN FRACTIONATION BASED ON pI |
| EP2773743B1 (en) | 2011-11-04 | 2019-05-22 | Bio-Rad Laboratories, Inc. | Affinity methods and compositions employing electronic control of ph |
| CN102565171A (zh) * | 2012-01-05 | 2012-07-11 | 厦门大学 | 一种用于等电聚焦分离的微流控芯片 |
| US9658195B2 (en) | 2012-02-15 | 2017-05-23 | Bio-Rad Laboratories, Inc. | Electronic control of pH and ionic strength |
| US9321012B2 (en) | 2012-04-04 | 2016-04-26 | Bio-Rad Laboratories, Inc. | Electronic protein fractionation |
| CN104034789A (zh) * | 2013-04-02 | 2014-09-10 | 上海交通大学 | 蛋白质等电聚焦电泳的装置 |
| CN106267304B (zh) * | 2015-06-09 | 2019-10-18 | 海南光宇生物科技有限公司 | 具有酸碱性的生物纤维素凝胶膜及由其制备的医用敷料 |
| CN106260992B (zh) * | 2015-06-09 | 2020-02-18 | 海南椰国食品有限公司 | 一种含有酸性椰果和/或碱性椰果的食品 |
| EP3653121A1 (en) * | 2018-11-14 | 2020-05-20 | Koninklijke Philips N.V. | Sensor unit, body fluid monitoring device and method for detecting an analyte |
| CN119470588A (zh) * | 2024-11-18 | 2025-02-18 | 中国科学院空天信息创新研究院 | 集成式多种重金属检测微传感器 |
Citations (3)
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| CN1462368A (zh) * | 2000-09-21 | 2003-12-17 | 格哈德·韦伯 | 用于分析电泳和制备电泳的介质 |
| CN1549924A (zh) * | 2001-07-16 | 2004-11-24 | �����ʸ���˹�ع�˾ | 通过等电点分析生物分子的缓冲液的阵列 |
| CN1558460A (zh) * | 2004-02-13 | 2004-12-29 | 清华大学 | 一种质子交换膜燃料电池多元催化剂的制备方法 |
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| WO1987001206A1 (en) * | 1985-08-21 | 1987-02-26 | William Rudolph Hargreaves | Methods and devices for separating, mixing, and detecting components in specific binding assays |
| US4670119A (en) * | 1985-10-25 | 1987-06-02 | Hurd Stanley M | Isoelectric focusing device and process |
| US4900414A (en) * | 1988-08-19 | 1990-02-13 | Drug Delivery Systems Inc. | Commercial separation system and method using electrokinetic techniques |
| US5160594A (en) | 1989-03-08 | 1992-11-03 | Board Of Regents Of The University Of Texas System | Apparatus and methods for isoelectric focusing of amphoteric substances incorporating ion selective membranes in electrode chambers |
| DE3929137C1 (https=) * | 1989-09-01 | 1991-02-28 | Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung Ev, 8000 Muenchen, De | |
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| WO2009027970A2 (en) | 2007-08-27 | 2009-03-05 | Technion - Research & Development Foundation Ltd | Ph gradients controlled by electrolysis, and their use in isoelectric focusing |
| WO2011021195A1 (en) * | 2009-08-18 | 2011-02-24 | Technion Research & Development Foundation Ltd. | Methods and devices of separating molecular analytes |
| EP2467709B1 (en) | 2009-08-18 | 2018-02-28 | Technion Research & Development Foundation Ltd. | Proton concentration topographies, methods and devices for producing the same |
| WO2013067529A1 (en) * | 2011-11-04 | 2013-05-10 | Bio-Rad Laboratories, Inc. | PROTEIN FRACTIONATION BASED ON pI |
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| CN1462368A (zh) * | 2000-09-21 | 2003-12-17 | 格哈德·韦伯 | 用于分析电泳和制备电泳的介质 |
| CN1549924A (zh) * | 2001-07-16 | 2004-11-24 | �����ʸ���˹�ع�˾ | 通过等电点分析生物分子的缓冲液的阵列 |
| CN1558460A (zh) * | 2004-02-13 | 2004-12-29 | 清华大学 | 一种质子交换膜燃料电池多元催化剂的制备方法 |
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| EP2193100B1 (en) | 2014-05-07 |
| EP2193100A2 (en) | 2010-06-09 |
| JP2010538255A (ja) | 2010-12-09 |
| CA2697649A1 (en) | 2009-03-05 |
| AU2008293381B2 (en) | 2012-07-19 |
| KR20100053672A (ko) | 2010-05-20 |
| CN101868425A (zh) | 2010-10-20 |
| EP2559666A2 (en) | 2013-02-20 |
| JP5702142B2 (ja) | 2015-04-15 |
| US10132776B2 (en) | 2018-11-20 |
| CN101868425B (zh) | 2013-01-02 |
| AU2008293381A1 (en) | 2009-03-05 |
| EP2559666A3 (en) | 2013-04-03 |
| US9274082B2 (en) | 2016-03-01 |
| WO2009027970A3 (en) | 2009-05-14 |
| WO2009027970A2 (en) | 2009-03-05 |
| CA2697649C (en) | 2016-08-09 |
| US20160178578A1 (en) | 2016-06-23 |
| CN103134843A (zh) | 2013-06-05 |
| US20100307920A1 (en) | 2010-12-09 |
| EP2559666B1 (en) | 2014-07-23 |
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