JP2010538019A5 - - Google Patents
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- Publication number
- JP2010538019A5 JP2010538019A5 JP2010523180A JP2010523180A JP2010538019A5 JP 2010538019 A5 JP2010538019 A5 JP 2010538019A5 JP 2010523180 A JP2010523180 A JP 2010523180A JP 2010523180 A JP2010523180 A JP 2010523180A JP 2010538019 A5 JP2010538019 A5 JP 2010538019A5
- Authority
- JP
- Japan
- Prior art keywords
- cation
- compound
- formula
- ammonium
- organism
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CCC(C*)O[C@@]1C=CC[C@@](C)[C@]1NC(C)=* Chemical compound CCC(C*)O[C@@]1C=CC[C@@](C)[C@]1NC(C)=* 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96949107P | 2007-08-31 | 2007-08-31 | |
| US60/969,491 | 2007-08-31 | ||
| US4850708P | 2008-04-28 | 2008-04-28 | |
| US61/048,507 | 2008-04-28 | ||
| PCT/US2008/074914 WO2009029888A2 (en) | 2007-08-31 | 2008-08-29 | Synthesis of oseltamivir containing phosphonate congeners with anti-influenza activity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010538019A JP2010538019A (ja) | 2010-12-09 |
| JP2010538019A5 true JP2010538019A5 (https=) | 2011-10-13 |
| JP5509080B2 JP5509080B2 (ja) | 2014-06-04 |
Family
ID=40388153
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010523180A Expired - Fee Related JP5509080B2 (ja) | 2007-08-31 | 2008-08-29 | 抗インフルエンザ活性を有するオセルタミビル含有ホスホネートコンジナーの合成 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7888337B2 (https=) |
| EP (1) | EP2190439B1 (https=) |
| JP (1) | JP5509080B2 (https=) |
| KR (1) | KR101535691B1 (https=) |
| CN (1) | CN101883569B (https=) |
| AU (1) | AU2008292859C1 (https=) |
| CA (1) | CA2697837C (https=) |
| WO (1) | WO2009029888A2 (https=) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7960139B2 (en) | 2007-03-23 | 2011-06-14 | Academia Sinica | Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells |
| JP5986745B2 (ja) | 2008-07-15 | 2016-09-06 | アカデミア シニカＡｃａｄｅｍｉａ Ｓｉｎｉｃａ | Ｐｔｆｅ様のアルミニウム・コート・ガラススライド上のグリカンアレイおよび関連する方法 |
| EA201101564A1 (ru) | 2009-05-15 | 2012-07-30 | Редкс Фарма Лимитед | Редокс производные лекарственных средств |
| US11377485B2 (en) | 2009-12-02 | 2022-07-05 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| US10087236B2 (en) | 2009-12-02 | 2018-10-02 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| US10338069B2 (en) | 2010-04-12 | 2019-07-02 | Academia Sinica | Glycan arrays for high throughput screening of viruses |
| CN103068378B (zh) * | 2010-05-10 | 2016-07-06 | 中央研究院 | 具有抗流感活性的扎那米韦膦酸酯同类物及其制备方法 |
| US8515882B2 (en) | 2010-11-18 | 2013-08-20 | International Business Machines Corporation | Efficient storage of individuals for optimization simulation |
| US8489526B2 (en) | 2010-11-24 | 2013-07-16 | International Business Machines Corporation | Controlling quarantining and biasing in cataclysms for optimization simulations |
| US9563844B2 (en) | 2011-06-30 | 2017-02-07 | International Business Machines Corporation | Speculative asynchronous sub-population evolutionary computing utilizing a termination speculation threshold |
| KR101331167B1 (ko) * | 2011-08-26 | 2013-11-19 | 주식회사 씨트리 | 신규한 오셀타미비르 유도체 및 그 제조방법 |
| DE102011117128A1 (de) * | 2011-10-28 | 2013-05-02 | Christian-Albrechts-Universität Zu Kiel | Verbindungen zur Therapie der Influenza |
| US9165247B2 (en) | 2012-01-04 | 2015-10-20 | International Business Machines Corporation | Using global and local catastrophes across sub-populations in parallel evolutionary computing |
| US10130714B2 (en) | 2012-04-14 | 2018-11-20 | Academia Sinica | Enhanced anti-influenza agents conjugated with anti-inflammatory activity |
| WO2014031498A1 (en) | 2012-08-18 | 2014-02-27 | Academia Sinica | Cell-permeable probes for identification and imaging of sialidases |
| CN103848762B (zh) * | 2012-11-30 | 2016-08-31 | 北京普禄德医药科技有限公司 | 神经氨酸苷酶抑制剂的前药及其组合物和用途 |
| RU2521593C1 (ru) * | 2013-02-27 | 2014-06-27 | Общество с ограниченной ответственностью "Интеллектуальный Диалог" | Моно и дифторзамещенные этил (3r,4r,5s)-5-азидо-4-ацетиламино-3-(1-этилпропокси)-циклогексен-1-карбоксилаты, способ получения и применения |
| US9305257B2 (en) | 2013-05-20 | 2016-04-05 | International Business Machines Corporation | Adaptive cataclysms in genetic algorithms |
| EP3013365B1 (en) | 2013-06-26 | 2019-06-05 | Academia Sinica | Rm2 antigens and use thereof |
| WO2014210564A1 (en) | 2013-06-27 | 2014-12-31 | Academia Sinica | Glycan conjugates and use thereof |
| US9782476B2 (en) | 2013-09-06 | 2017-10-10 | Academia Sinica | Human iNKT cell activation using glycolipids with altered glycosyl groups |
| US10150818B2 (en) | 2014-01-16 | 2018-12-11 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
| CA2937123A1 (en) | 2014-01-16 | 2015-07-23 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
| WO2015148915A1 (en) | 2014-03-27 | 2015-10-01 | Academia Sinica | Reactive labelling compounds and uses thereof |
| KR102512592B1 (ko) | 2014-05-27 | 2023-03-21 | 아카데미아 시니카 | 항-ｈｅｒ2 글리코항체 및 이의 용도 |
| KR20170003720A (ko) | 2014-05-27 | 2017-01-09 | 아카데미아 시니카 | 항-ｃｄ20 글리코항체 및 이의 용도 |
| US10118969B2 (en) | 2014-05-27 | 2018-11-06 | Academia Sinica | Compositions and methods relating to universal glycoforms for enhanced antibody efficacy |
| CA2950423A1 (en) | 2014-05-27 | 2015-12-03 | Academia Sinica | Compositions and methods relating to universal glycoforms for enhanced antibody efficacy |
| CN106714829A (zh) | 2014-05-28 | 2017-05-24 | 中央研究院 | 抗TNF‑α醣抗体及其用途 |
| CA2960712A1 (en) | 2014-09-08 | 2016-03-17 | Academia Sinica | Human inkt cell activation using glycolipids |
| US9975965B2 (en) | 2015-01-16 | 2018-05-22 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
| US10495645B2 (en) | 2015-01-16 | 2019-12-03 | Academia Sinica | Cancer markers and methods of use thereof |
| AU2015378564A1 (en) | 2015-01-24 | 2017-07-13 | Academia Sinica | Novel glycan conjugates and methods of use thereof |
| WO2017156192A1 (en) | 2016-03-08 | 2017-09-14 | Academia Sinica | Methods for modular synthesis of n-glycans and arrays thereof |
| EP3500594A4 (en) | 2016-08-22 | 2020-03-11 | Cho Pharma Inc. | ANTIBODIES, BINDING FRAGMENTS AND METHOD FOR USE |
| CN114315626A (zh) * | 2021-12-21 | 2022-04-12 | 艾希尔（深圳）药物研发有限公司 | 一种奥司他韦脱烷基杂质的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ288492B6 (en) * | 1990-04-24 | 2001-06-13 | Biota Scient Management | Derivatives of alpha-D-neuraminic acid, process of their preparation, their use and pharmaceutical preparations based thereon |
| WO1992006691A1 (en) | 1990-10-19 | 1992-04-30 | Biota Scientific Management Pty. Ltd. | Anti-viral compounds that bind the active site of influenza neuramidase and display in vivo activity against orthomyxovirus and paramyxovirus |
| BR9607098B8 (pt) * | 1995-02-27 | 2014-11-18 | Gilead Sciences Inc | Composto e composição farmacêutica. |
| US5763483A (en) | 1995-12-29 | 1998-06-09 | Gilead Sciences, Inc. | Carbocyclic compounds |
| US20080009639A1 (en) | 2006-07-10 | 2008-01-10 | Apotex Pharmachem Inc. | Preparation of oseltamivir phosphate (Tamiflu) and intermediates starting from D-glucose or D-xylose |
-
2008
- 2008-08-29 JP JP2010523180A patent/JP5509080B2/ja not_active Expired - Fee Related
- 2008-08-29 US US12/201,955 patent/US7888337B2/en not_active Expired - Fee Related
- 2008-08-29 WO PCT/US2008/074914 patent/WO2009029888A2/en not_active Ceased
- 2008-08-29 CN CN2008801134612A patent/CN101883569B/zh not_active Expired - Fee Related
- 2008-08-29 AU AU2008292859A patent/AU2008292859C1/en not_active Ceased
- 2008-08-29 CA CA2697837A patent/CA2697837C/en not_active Expired - Fee Related
- 2008-08-29 KR KR1020107006286A patent/KR101535691B1/ko not_active Expired - Fee Related
- 2008-08-29 EP EP08828468.2A patent/EP2190439B1/en not_active Not-in-force
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