JP2010536886A5 - - Google Patents
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- Publication number
- JP2010536886A5 JP2010536886A5 JP2010522103A JP2010522103A JP2010536886A5 JP 2010536886 A5 JP2010536886 A5 JP 2010536886A5 JP 2010522103 A JP2010522103 A JP 2010522103A JP 2010522103 A JP2010522103 A JP 2010522103A JP 2010536886 A5 JP2010536886 A5 JP 2010536886A5
- Authority
- JP
- Japan
- Prior art keywords
- met
- antigen
- binding fragment
- specific mab
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/845,023 US7892770B2 (en) | 2007-08-24 | 2007-08-24 | Monoclonal antibody which binds cMet (HGFR) in formalin-fixed and paraffin-embedded tissues and related methods |
| US11/845,023 | 2007-08-24 | ||
| PCT/US2008/074249 WO2009029591A2 (en) | 2007-08-24 | 2008-08-25 | Monoclonal antibody which binds met in formalin-fixed and paraffin-embedded tissues and related methods |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010536886A JP2010536886A (ja) | 2010-12-02 |
| JP2010536886A5 true JP2010536886A5 (https=) | 2011-06-30 |
| JP4806469B2 JP4806469B2 (ja) | 2011-11-02 |
Family
ID=40193999
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010522103A Expired - Fee Related JP4806469B2 (ja) | 2007-08-24 | 2008-08-25 | ホルマリン固定およびパラフィン包埋された組織においてＭｅｔを結合するモノクローナル抗体および関連する方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7892770B2 (https=) |
| EP (1) | EP2195345B1 (https=) |
| JP (1) | JP4806469B2 (https=) |
| CA (1) | CA2715103C (https=) |
| ES (1) | ES2386188T3 (https=) |
| WO (1) | WO2009029591A2 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1415156B1 (en) | 2001-07-10 | 2009-09-02 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for detecting the activation state of multiple proteins in single cells |
| CN101073002B (zh) * | 2004-09-15 | 2012-08-08 | 英特基因有限公司 | 微流体装置 |
| US7892770B2 (en) * | 2007-08-24 | 2011-02-22 | Van Andel Research Institute | Monoclonal antibody which binds cMet (HGFR) in formalin-fixed and paraffin-embedded tissues and related methods |
| EP2287197A1 (en) * | 2009-08-21 | 2011-02-23 | Pierre Fabre Medicament | Anti-cMET antibody and its use for the detection and the diagnosis of cancer |
| GB201004551D0 (en) | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer |
| EP2576622A4 (en) | 2010-06-01 | 2013-11-27 | Univ Monash | ON THE UNPROCESSED RECEPTOR TYROSINE KINASE C-MET TARGETED ANTIBODIES |
| EP2402370A1 (en) * | 2010-06-29 | 2012-01-04 | Pierre Fabre Médicament | Novel antibody for the diagnosis and/or prognosis of cancer |
| RU2608644C2 (ru) | 2010-11-03 | 2017-01-23 | арДЖЕН-ИКС Н.В. | Антитела против белка рецептора с-мет |
| WO2012178038A1 (en) | 2011-06-24 | 2012-12-27 | The Broad Institute, Inc. | Methods of treating cancer |
| CA2843771A1 (en) | 2011-09-20 | 2013-03-28 | Eli Lilly And Company | Anti-c-met antibodies |
| US9926364B2 (en) | 2011-11-03 | 2018-03-27 | Argen-X N.V. | Chimeric human-llama antigens and methods of use |
| EP3560509B1 (en) | 2011-12-22 | 2024-01-31 | Children's Medical Center Corporation | Saposin-a derived peptides and uses thereof |
| WO2013169532A1 (en) * | 2012-05-09 | 2013-11-14 | Eli Lilly And Company | Anti-c-met antibodies |
| US9168300B2 (en) | 2013-03-14 | 2015-10-27 | Oncomed Pharmaceuticals, Inc. | MET-binding agents and uses thereof |
| RU2016141385A (ru) | 2014-03-24 | 2018-04-28 | Дженентек, Инк. | Лечение рака антагонистами с-мет и их корреляция с экспрессией hgf |
| ES2748295T3 (es) | 2014-09-16 | 2020-03-16 | Symphogen As | Anticuerpos anti-MET y composiciones |
| PE20230343A1 (es) | 2015-12-11 | 2023-03-01 | Immatics Biotechnologies Gmbh | Peptidos que estimulan respuestas inmunitarias antitumorales |
| GB201521894D0 (en) | 2015-12-11 | 2016-01-27 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against various cancers |
| TWI782930B (zh) | 2016-11-16 | 2022-11-11 | 美商再生元醫藥公司 | 抗ｍｅｔ抗體，結合ｍｅｔ之雙特異性抗原結合分子及其使用方法 |
| BR112021016149A2 (pt) | 2019-02-26 | 2021-10-13 | Janssen Biotech, Inc. | Terapias de combinação e estratificação de pacientes com anticorpos biespecíficos anti-egfr/c-met |
| US11850248B2 (en) | 2019-05-14 | 2023-12-26 | Yuhan Corporation | Therapies with 3rd generation EGFR tyrosine kinase inhibitors |
| US11879013B2 (en) | 2019-05-14 | 2024-01-23 | Janssen Biotech, Inc. | Combination therapies with bispecific anti-EGFR/c-Met antibodies and third generation EGFR tyrosine kinase inhibitors |
| AU2020349462A1 (en) | 2019-09-16 | 2022-03-03 | Regeneron Pharmaceuticals, Inc. | Radiolabeled MET binding proteins for immuno-PET imaging |
| JP7783182B2 (ja) | 2020-02-12 | 2025-12-09 | ヤンセン バイオテツク，インコーポレーテツド | ｃ－ＭＥＴエクソン１４スキッピング変異を有する患者の治療 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5917017A (en) * | 1994-06-08 | 1999-06-29 | President And Fellows Of Harvard College | Diphtheria toxin vaccines bearing a mutated R domain |
| KR20030094281A (ko) * | 2001-03-12 | 2003-12-11 | 모노젠, 인크. | 세포에 기초한 질병상태의 검출 및 질병상태의 구별 |
| US7892770B2 (en) * | 2007-08-24 | 2011-02-22 | Van Andel Research Institute | Monoclonal antibody which binds cMet (HGFR) in formalin-fixed and paraffin-embedded tissues and related methods |
-
2007
- 2007-08-24 US US11/845,023 patent/US7892770B2/en not_active Expired - Fee Related
-
2008
- 2008-08-25 JP JP2010522103A patent/JP4806469B2/ja not_active Expired - Fee Related
- 2008-08-25 WO PCT/US2008/074249 patent/WO2009029591A2/en not_active Ceased
- 2008-08-25 CA CA2715103A patent/CA2715103C/en not_active Expired - Fee Related
- 2008-08-25 EP EP08828206A patent/EP2195345B1/en not_active Not-in-force
- 2008-08-25 US US12/679,247 patent/US8309315B2/en not_active Expired - Fee Related
- 2008-08-25 ES ES08828206T patent/ES2386188T3/es active Active
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