JP2010536388A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010536388A5 JP2010536388A5 JP2010522134A JP2010522134A JP2010536388A5 JP 2010536388 A5 JP2010536388 A5 JP 2010536388A5 JP 2010522134 A JP2010522134 A JP 2010522134A JP 2010522134 A JP2010522134 A JP 2010522134A JP 2010536388 A5 JP2010536388 A5 JP 2010536388A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- compound
- acid sequence
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims description 82
- 108091033319 polynucleotide Proteins 0.000 claims description 77
- 102000040430 polynucleotide Human genes 0.000 claims description 77
- 239000002157 polynucleotide Substances 0.000 claims description 77
- 229920001184 polypeptide Polymers 0.000 claims description 65
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 65
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 65
- 210000004027 cell Anatomy 0.000 claims description 64
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 57
- 239000012634 fragment Substances 0.000 claims description 52
- 238000000034 method Methods 0.000 claims description 47
- 210000004443 dendritic cell Anatomy 0.000 claims description 35
- 239000002243 precursor Substances 0.000 claims description 33
- 239000000427 antigen Substances 0.000 claims description 29
- 108091007433 antigens Proteins 0.000 claims description 29
- 102000036639 antigens Human genes 0.000 claims description 29
- 239000000203 mixture Substances 0.000 claims description 27
- 239000013598 vector Substances 0.000 claims description 21
- 230000009261 transgenic effect Effects 0.000 claims description 20
- 239000003814 drug Substances 0.000 claims description 19
- 239000000284 extract Substances 0.000 claims description 18
- 230000028993 immune response Effects 0.000 claims description 15
- 238000004519 manufacturing process Methods 0.000 claims description 13
- 239000002773 nucleotide Substances 0.000 claims description 13
- 125000003729 nucleotide group Chemical group 0.000 claims description 13
- 238000004113 cell culture Methods 0.000 claims description 12
- 201000010099 disease Diseases 0.000 claims description 11
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 11
- 208000015181 infectious disease Diseases 0.000 claims description 11
- 230000000890 antigenic effect Effects 0.000 claims description 10
- 239000000126 substance Substances 0.000 claims description 10
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims description 8
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims description 8
- 208000023275 Autoimmune disease Diseases 0.000 claims description 7
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims description 7
- 102000006496 Immunoglobulin Heavy Chains Human genes 0.000 claims description 6
- 108010019476 Immunoglobulin Heavy Chains Proteins 0.000 claims description 6
- 102000013463 Immunoglobulin Light Chains Human genes 0.000 claims description 6
- 108010065825 Immunoglobulin Light Chains Proteins 0.000 claims description 6
- 206010028980 Neoplasm Diseases 0.000 claims description 6
- 201000011510 cancer Diseases 0.000 claims description 6
- 238000000338 in vitro Methods 0.000 claims description 6
- 241001465754 Metazoa Species 0.000 claims description 5
- 206010020751 Hypersensitivity Diseases 0.000 claims description 4
- 241001442539 Plasmodium sp. Species 0.000 claims description 4
- 208000026935 allergic disease Diseases 0.000 claims description 4
- 230000007815 allergy Effects 0.000 claims description 4
- 239000003937 drug carrier Substances 0.000 claims description 4
- 230000001717 pathogenic effect Effects 0.000 claims description 4
- 229940124597 therapeutic agent Drugs 0.000 claims description 4
- 230000001225 therapeutic effect Effects 0.000 claims description 4
- 102100024649 Cell adhesion molecule 1 Human genes 0.000 claims description 3
- 101000884271 Homo sapiens Signal transducer CD24 Proteins 0.000 claims description 3
- 102100022297 Integrin alpha-X Human genes 0.000 claims description 3
- 125000000729 N-terminal amino-acid group Chemical group 0.000 claims description 3
- 102100038081 Signal transducer CD24 Human genes 0.000 claims description 3
- 102100034922 T-cell surface glycoprotein CD8 alpha chain Human genes 0.000 claims description 3
- 239000013566 allergen Substances 0.000 claims description 3
- 210000004102 animal cell Anatomy 0.000 claims description 3
- 210000000628 antibody-producing cell Anatomy 0.000 claims description 3
- 230000002458 infectious effect Effects 0.000 claims description 3
- 206010025135 lupus erythematosus Diseases 0.000 claims description 3
- 241000238631 Hexapoda Species 0.000 claims description 2
- 241000223960 Plasmodium falciparum Species 0.000 claims description 2
- 241000223810 Plasmodium vivax Species 0.000 claims description 2
- 239000002671 adjuvant Substances 0.000 claims description 2
- -1 autoantigen Substances 0.000 claims description 2
- 230000001580 bacterial effect Effects 0.000 claims description 2
- 231100000433 cytotoxic Toxicity 0.000 claims description 2
- 230000001472 cytotoxic effect Effects 0.000 claims description 2
- 229940079593 drug Drugs 0.000 claims description 2
- 239000013604 expression vector Substances 0.000 claims description 2
- 239000002502 liposome Substances 0.000 claims description 2
- 230000000144 pharmacologic effect Effects 0.000 claims description 2
- 210000005253 yeast cell Anatomy 0.000 claims description 2
- 101000763314 Homo sapiens Thrombomodulin Proteins 0.000 claims 1
- 102100026966 Thrombomodulin Human genes 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 210000001787 dendrite Anatomy 0.000 claims 1
- 210000004408 hybridoma Anatomy 0.000 description 8
- 108091032973 (ribonucleotides)n+m Proteins 0.000 description 5
- 102000040650 (ribonucleotides)n+m Human genes 0.000 description 5
- 230000000692 anti-sense effect Effects 0.000 description 4
- 230000003197 catalytic effect Effects 0.000 description 4
- 108091034117 Oligonucleotide Proteins 0.000 description 3
- 210000001744 T-lymphocyte Anatomy 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000001943 fluorescence-activated cell sorting Methods 0.000 description 3
- 229940126062 Compound A Drugs 0.000 description 2
- NLDMNSXOCDLTTB-UHFFFAOYSA-N Heterophylliin A Natural products O1C2COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC2C(OC(=O)C=2C=C(O)C(O)=C(O)C=2)C(O)C1OC(=O)C1=CC(O)=C(O)C(O)=C1 NLDMNSXOCDLTTB-UHFFFAOYSA-N 0.000 description 2
- 108700011259 MicroRNAs Proteins 0.000 description 2
- 108091028043 Nucleic acid sequence Proteins 0.000 description 2
- 230000004913 activation Effects 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- 108050009406 C-type lectin-like Proteins 0.000 description 1
- 102000002086 C-type lectin-like Human genes 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 108010041986 DNA Vaccines Proteins 0.000 description 1
- 229940021995 DNA vaccine Drugs 0.000 description 1
- 206010035226 Plasma cell myeloma Diseases 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 230000001404 mediated effect Effects 0.000 description 1
- 108020004999 messenger RNA Proteins 0.000 description 1
- 239000002679 microRNA Substances 0.000 description 1
- 201000000050 myeloid neoplasm Diseases 0.000 description 1
- 230000004962 physiological condition Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 210000004881 tumor cell Anatomy 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96911807P | 2007-08-30 | 2007-08-30 | |
| US5286508P | 2008-05-13 | 2008-05-13 | |
| PCT/AU2008/001294 WO2009026660A1 (en) | 2007-08-30 | 2008-08-29 | Dendritic cell marker and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014150520A Division JP6095616B2 (ja) | 2007-08-30 | 2014-07-24 | 樹状細胞マーカーおよびその使用法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010536388A JP2010536388A (ja) | 2010-12-02 |
| JP2010536388A5 true JP2010536388A5 (cg-RX-API-DMAC7.html) | 2011-09-22 |
Family
ID=40386591
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010522134A Pending JP2010536388A (ja) | 2007-08-30 | 2008-08-29 | 樹状細胞マーカーおよびその使用法 |
| JP2014150520A Active JP6095616B2 (ja) | 2007-08-30 | 2014-07-24 | 樹状細胞マーカーおよびその使用法 |
| JP2016206463A Active JP6433470B2 (ja) | 2007-08-30 | 2016-10-21 | 樹状細胞マーカーおよびその使用法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014150520A Active JP6095616B2 (ja) | 2007-08-30 | 2014-07-24 | 樹状細胞マーカーおよびその使用法 |
| JP2016206463A Active JP6433470B2 (ja) | 2007-08-30 | 2016-10-21 | 樹状細胞マーカーおよびその使用法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US8426565B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2195346B1 (cg-RX-API-DMAC7.html) |
| JP (3) | JP2010536388A (cg-RX-API-DMAC7.html) |
| CN (1) | CN101970491A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2008294074B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0815848A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2697448C (cg-RX-API-DMAC7.html) |
| IL (1) | IL204157A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2009026660A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009026660A1 (en) | 2007-08-30 | 2009-03-05 | Walter And Eliza Hall Institute Of Medical Research | Dendritic cell marker and uses thereof |
| US20110110861A1 (en) * | 2008-05-13 | 2011-05-12 | Mireille Hanna Lahoud | Methods of Detecting Cells with a Disrupted Cell Membrane, Cells Infected with A Pathogen, Dying Cells or Dead Cells |
| JP2012521199A (ja) * | 2009-03-23 | 2012-09-13 | ウォルター アンド エリザ ホール インスティテュート オブ メディカル リサーチ | 免疫応答を調節するための化合物および方法 |
| CN102741288B (zh) | 2009-08-29 | 2015-08-19 | Abbvie公司 | 治疗用dll4结合蛋白 |
| KR101853278B1 (ko) * | 2010-03-02 | 2018-05-02 | 애브비 인코포레이티드 | 치료학적 ｄｌｌ４ 결합 단백질 |
| RS55495B1 (sr) | 2010-08-02 | 2017-04-28 | Regeneron Pharma | Miševi koji stvaraju vezujuće proteine koji sadrže vl domene |
| SI3865581T1 (sl) | 2011-08-05 | 2024-12-31 | Regeneron Pharmaceuticals, Inc. | Miši s humanizirano univerzalno lahko verigo |
| EP2568051A1 (en) | 2011-09-07 | 2013-03-13 | Stallergenes S.A. | Methods for identifying dendritic cell subsets, for determining if a patient is developing a regulatory or an effector immune response, and for determining response to immunotherapy |
| PL3597038T3 (pl) * | 2012-02-01 | 2021-11-08 | Regeneron Pharmaceuticals, Inc. | Humanizowane gryzonie wykazujące ekspresję łańcuchów ciężkich zawierających domeny vl |
| CN103483441A (zh) * | 2012-06-10 | 2014-01-01 | 复旦大学 | 恒河猴ny-eso-1蛋白、其编码基因及应用 |
| CN103720719B (zh) * | 2013-10-11 | 2016-07-06 | 长沙赢润生物技术有限公司 | 一项DC和Treg细胞治疗红斑狼疮的技术 |
| ES2872475T3 (es) | 2014-03-21 | 2021-11-02 | Regeneron Pharma | Animales no humanos que producen proteínas de unión de dominio único |
| WO2015143406A2 (en) | 2014-03-21 | 2015-09-24 | Regeneron Pharmaceuticals, Inc. | Vl antigen binding proteins exhibiting distinct binding characteristics |
| CN104387453A (zh) * | 2014-12-08 | 2015-03-04 | 深圳市同康生物医药有限公司 | 树突状细胞靶向肽及编码基因及应用 |
| JP2018508224A (ja) | 2015-03-19 | 2018-03-29 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | 抗原を結合する軽鎖可変領域を選択する非ヒト動物 |
| EP3397645A1 (en) * | 2015-12-28 | 2018-11-07 | Innate Pharma | VARIABLE REGIONS FOR NKp46 BINDING PROTEINS |
| JP2020505034A (ja) * | 2017-01-20 | 2020-02-20 | ジュノ セラピューティクス ゲーエムベーハー | 細胞表面コンジュゲートならびに関連する細胞組成物および方法 |
| WO2019243461A1 (en) * | 2018-06-19 | 2019-12-26 | Fondazione Telethon | Production of engineered dendritic cells and uses thereof |
| EP3841112A1 (en) | 2018-08-24 | 2021-06-30 | Codiak BioSciences, Inc. | Extracellular vesicles targeting dendritic cells and uses thereof |
| US12233356B2 (en) | 2019-03-21 | 2025-02-25 | Lonza Sales Ag | Process for preparing extracellular vesicles |
| AU2020240135A1 (en) | 2019-03-21 | 2021-10-14 | Lonza Sales Ag | Extracellular vesicles for vaccine delivery |
| CN114008069A (zh) | 2019-04-17 | 2022-02-01 | 科迪亚克生物科学公司 | 外来体和aav的组合物 |
| IL272194A (en) | 2020-01-22 | 2021-07-29 | Yeda Res & Dev | Multi-target antibodies for use in the treatment of diseases |
| WO2021184017A1 (en) | 2020-03-13 | 2021-09-16 | Codiak Biosciences, Inc. | Extracellular vesicles for treating neurological disorders |
| AU2021236763A1 (en) | 2020-03-20 | 2022-10-06 | Lonza Sales Ag | Extracellular vesicles for therapy |
| US20240082389A1 (en) | 2020-09-23 | 2024-03-14 | Lonza Sales Ag | Methods of producing extracellular vesicles |
| WO2022066883A1 (en) | 2020-09-23 | 2022-03-31 | Codiak Biosciences, Inc. | Extracellular vesicles comprising kras antigens and uses thereof |
| EP4225795A4 (en) * | 2020-10-05 | 2025-03-26 | Monash University | Clec9a antibodies |
| CN114563574B (zh) * | 2020-11-27 | 2025-03-04 | 中国科学院北京基因组研究所(国家生物信息中心) | 分子标记物组合及其用途 |
| IL286430A (en) | 2021-09-14 | 2023-04-01 | Yeda Res & Dev | Multispecific antibodies for use in the treatment of diseases |
| US11977085B1 (en) | 2023-09-05 | 2024-05-07 | Elan Ehrlich | Date rape drug detection device and method of using same |
| WO2025079599A1 (ja) * | 2023-10-11 | 2025-04-17 | 国立大学法人金沢大学 | サブセットレベルで細胞を標的化可能な担体およびその製造方法 |
| CN119661686B (zh) * | 2024-09-30 | 2025-09-30 | 中国农业大学 | 一种重组clec9a基因及其在提高动物的免疫和抗病能力中的应用 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4542225A (en) | 1984-08-29 | 1985-09-17 | Dana-Farber Cancer Institute, Inc. | Acid-cleavable compound |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| US5118606A (en) | 1988-09-02 | 1992-06-02 | The Regents Of The University Of California | Methods for detecting cellular pathology by assaying spectrin and spectrin breakdown products |
| US6075181A (en) | 1990-01-12 | 2000-06-13 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US5643578A (en) | 1992-03-23 | 1997-07-01 | University Of Massachusetts Medical Center | Immunization by inoculation of DNA transcription unit |
| US5536642A (en) * | 1993-09-09 | 1996-07-16 | Barbera-Guillem; Emilio | Diagnostic and prognostic methods for solid non-lymphoid tumors and their metastases |
| US5597569A (en) | 1993-10-25 | 1997-01-28 | Bristol-Myers Squibb Company | Bryodin 2 a ribosome-inactivating protein isolated from the plant Bryonia dioica |
| DE69536091D1 (de) | 1994-01-27 | 2010-09-09 | Univ Massachusetts Medical | Immunisierung durch Impfung von DNS Transkriptionseinheit |
| US6117985A (en) * | 1995-06-16 | 2000-09-12 | Stemcell Technologies Inc. | Antibody compositions for preparing enriched cell preparations |
| US5939400A (en) | 1996-02-26 | 1999-08-17 | The Board Of Trustees Of The Leland Stanford Junior University | DNA vaccination for induction of suppressive T cell response |
| AU3210997A (en) | 1996-05-24 | 1997-12-09 | University Of Maryland At Baltimore | Dna vaccines for eliciting a mucosal immune response |
| US6506559B1 (en) | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
| CA2323726C (en) | 1998-03-20 | 2005-02-08 | Benitec Australia Ltd. | Control of gene expression |
| DK1068311T3 (da) | 1998-04-08 | 2011-08-08 | Commw Scient Ind Res Org | Fremgangsmåder og midler til opnåelse af modificerede fænotyper |
| EP1046651A1 (en) | 1999-04-19 | 2000-10-25 | Koninklijke Universiteit Nijmegen | Composition and method for modulating dendritic cell-T interaction |
| AUPQ002399A0 (en) | 1999-04-28 | 1999-05-20 | Australian National University, The | Model membrane systems |
| US6326193B1 (en) | 1999-11-05 | 2001-12-04 | Cambria Biosciences, Llc | Insect control agent |
| US20020090672A1 (en) | 2000-01-31 | 2002-07-11 | Rosen Craig A. | Nucleic acids, proteins, and antibodies |
| CA2380443C (en) * | 2000-05-26 | 2013-03-12 | Ginette Dubuc | Single-domain antigen-binding antibody fragments derived from llama antibodies |
| WO2003025130A2 (en) * | 2001-09-14 | 2003-03-27 | Incyte Genomics, Inc. | Receptors and membrane-associated proteins |
| EP1504099A4 (en) * | 2001-12-10 | 2006-05-10 | Nuvelo Inc | NEW NUCLEIC ACIDS AND POLYPEPTIDES |
| AU2003235099A1 (en) * | 2002-04-23 | 2003-11-10 | K. K. Dnaform | Novel proteins and dnas encoding the same |
| US6813008B2 (en) | 2002-06-10 | 2004-11-02 | Palantyr Research, Llc | Microdissection optical system |
| US9259459B2 (en) * | 2003-01-31 | 2016-02-16 | Celldex Therapeutics Inc. | Antibody vaccine conjugates and uses therefor |
| WO2004108079A2 (en) | 2003-05-30 | 2004-12-16 | University Of Massachusetts | Parkin-interacting proteins |
| JP4970035B2 (ja) | 2003-08-21 | 2012-07-04 | リポテック・プロプライエタリー・リミテッド | ｉｎｖｉｖｏにおける樹状細胞の標的化 |
| PL1691837T3 (pl) * | 2003-12-10 | 2012-11-30 | Squibb & Sons Llc | IP-10 przeciwciała i ich zastosowanie |
| NZ560737A (en) | 2005-02-11 | 2010-01-29 | Cambridge Scient Pty Ltd | Analgesic and anti-inflammatory composition |
| WO2007002183A2 (en) | 2005-06-21 | 2007-01-04 | Bausch & Lomb Incorporated | Drug delivery device for implanting in the eye comprising a drug core and a preformed permeable crystalline polymeric disc |
| EP1938104A2 (en) | 2005-10-17 | 2008-07-02 | Institute for Systems Biology | Tissue-and serum-derived glycoproteins and methods of their use |
| GB0805159D0 (en) * | 2008-03-19 | 2008-04-23 | Sancho Madrid David | Immune modulation via C-type lectin |
| WO2009026660A1 (en) | 2007-08-30 | 2009-03-05 | Walter And Eliza Hall Institute Of Medical Research | Dendritic cell marker and uses thereof |
| US20110110861A1 (en) | 2008-05-13 | 2011-05-12 | Mireille Hanna Lahoud | Methods of Detecting Cells with a Disrupted Cell Membrane, Cells Infected with A Pathogen, Dying Cells or Dead Cells |
| JP2012521199A (ja) | 2009-03-23 | 2012-09-13 | ウォルター アンド エリザ ホール インスティテュート オブ メディカル リサーチ | 免疫応答を調節するための化合物および方法 |
-
2008
- 2008-08-29 WO PCT/AU2008/001294 patent/WO2009026660A1/en not_active Ceased
- 2008-08-29 AU AU2008294074A patent/AU2008294074B2/en active Active
- 2008-08-29 BR BRPI0815848A patent/BRPI0815848A2/pt not_active Application Discontinuation
- 2008-08-29 CN CN2008801106595A patent/CN101970491A/zh active Pending
- 2008-08-29 JP JP2010522134A patent/JP2010536388A/ja active Pending
- 2008-08-29 CA CA2697448A patent/CA2697448C/en active Active
- 2008-08-29 EP EP08783037.8A patent/EP2195346B1/en active Active
- 2008-08-29 US US12/675,392 patent/US8426565B2/en active Active
-
2010
- 2010-02-25 IL IL204157A patent/IL204157A/en active IP Right Grant
-
2013
- 2013-03-21 US US13/848,503 patent/US9988431B2/en active Active
-
2014
- 2014-07-24 JP JP2014150520A patent/JP6095616B2/ja active Active
-
2016
- 2016-10-21 JP JP2016206463A patent/JP6433470B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010536388A5 (cg-RX-API-DMAC7.html) | ||
| US10870696B2 (en) | Treatment of fibrosis with interleukin-11 antibody | |
| JP7595696B2 (ja) | Ｃｄ３抗原結合性断片及びその使用 | |
| CA2904722C (en) | Methods and compositions relating to anti-ccr7 antigen binding proteins | |
| WO2022199590A1 (zh) | 一种靶向bcma的纳米抗体及其应用 | |
| CN102753579A (zh) | 抗钙粘着蛋白抗体 | |
| CN110872353B (zh) | 特异性结合pcsk9抗原的纳米抗体及其制备方法和应用 | |
| JP2023179450A (ja) | 抗－ヒトプログラム細胞死リガンド－１（ｐｄ－ｌ１）の抗体及びその用途 | |
| WO2021046299A1 (en) | Methods for identification of antigen binding specificity of antibodies | |
| WO2024017362A1 (zh) | 靶向gprc5d和/或bcma的嵌合抗原受体及其应用 | |
| CN113583124B (zh) | 一种抗前胃泌素释放肽单克隆抗体及其制备方法 | |
| CN101706507B (zh) | 用异硫氰酸荧光素标记的抗人cd45ra单抗的应用 | |
| CN117843788A (zh) | 一种抗gprc5d的抗体及其多特异性抗体和相关应用 | |
| WO2019183437A1 (en) | Methods and compositions for antibody to high affinity receptor for ige | |
| CN114933655B (zh) | 抗cd123抗体及其应用 | |
| CN100412193C (zh) | 抗人cd19鼠免疫球蛋白可变区基因及用途 | |
| US11180544B2 (en) | Method of producing antibody fragment | |
| CN116333149A (zh) | 一种结合pcsk9抗原的单域抗体及其制备方法 | |
| CN120040594A (zh) | 一种靶向flt3基因编辑通用型car-t细胞的制备方法和应用 | |
| CN114773485A (zh) | 抗人PD-L1抗体和TGFβRII的双功能融合蛋白分子 |