JP2010536380A5 - - Google Patents
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- Publication number
- JP2010536380A5 JP2010536380A5 JP2010522029A JP2010522029A JP2010536380A5 JP 2010536380 A5 JP2010536380 A5 JP 2010536380A5 JP 2010522029 A JP2010522029 A JP 2010522029A JP 2010522029 A JP2010522029 A JP 2010522029A JP 2010536380 A5 JP2010536380 A5 JP 2010536380A5
- Authority
- JP
- Japan
- Prior art keywords
- strand
- dsrna
- seq
- vector
- ribonucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000000295 complement effect Effects 0.000 claims 3
- 239000002773 nucleotide Substances 0.000 claims 3
- 125000003729 nucleotide group Chemical group 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 229920002477 rna polymer Polymers 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 230000002062 proliferating effect Effects 0.000 claims 2
- 102000040650 (ribonucleotides)n+m Human genes 0.000 claims 1
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 1
- 102000002812 Heat-Shock Proteins Human genes 0.000 claims 1
- 108010004889 Heat-Shock Proteins Proteins 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 230000001177 retroviral effect Effects 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 230000026683 transduction Effects 0.000 claims 1
- 238000010361 transduction Methods 0.000 claims 1
- 230000004614 tumor growth Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95709707P | 2007-08-21 | 2007-08-21 | |
| PCT/US2008/073872 WO2009026445A2 (en) | 2007-08-21 | 2008-08-21 | Methods and compositions for post-transcriptional gene silencing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010536380A JP2010536380A (ja) | 2010-12-02 |
| JP2010536380A5 true JP2010536380A5 (enExample) | 2011-10-06 |
Family
ID=40378991
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010522029A Pending JP2010536380A (ja) | 2007-08-21 | 2008-08-21 | 転写後遺伝子サイレンシングのための方法及び組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20100186102A1 (enExample) |
| EP (1) | EP2185702A4 (enExample) |
| JP (1) | JP2010536380A (enExample) |
| AU (1) | AU2008288846A1 (enExample) |
| CA (1) | CA2697055A1 (enExample) |
| WO (1) | WO2009026445A2 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX339050B (es) * | 2009-12-18 | 2016-05-09 | Novartis Ag | Composiciones organicas para tratar las enfermedades relacionadas con hsf1. |
| US20120308642A1 (en) * | 2011-05-27 | 2012-12-06 | Xavier University Of Louisiana | Inhibiting hepatitis c viral replication with sirna combinations |
| US20140351961A1 (en) * | 2011-08-31 | 2014-11-27 | Alexzander A. Asea | Compositions and methods for treatment of metastatic cancer |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20080023768A (ko) * | 2000-03-30 | 2008-03-14 | 화이트헤드 인스티튜트 포 바이오메디칼 리서치 | Ｒｎａ 간섭의 ｒｎａ 서열 특이적인 매개체 |
| EP2305813A3 (en) * | 2002-11-14 | 2012-03-28 | Dharmacon, Inc. | Fuctional and hyperfunctional sirna |
-
2008
- 2008-08-21 US US12/673,575 patent/US20100186102A1/en not_active Abandoned
- 2008-08-21 JP JP2010522029A patent/JP2010536380A/ja active Pending
- 2008-08-21 AU AU2008288846A patent/AU2008288846A1/en not_active Abandoned
- 2008-08-21 EP EP08827769A patent/EP2185702A4/en not_active Withdrawn
- 2008-08-21 CA CA2697055A patent/CA2697055A1/en not_active Abandoned
- 2008-08-21 WO PCT/US2008/073872 patent/WO2009026445A2/en not_active Ceased