JP2010536380A - 転写後遺伝子サイレンシングのための方法及び組成物 - Google Patents
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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Applications Claiming Priority (2)
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| US95709707P | 2007-08-21 | 2007-08-21 | |
| PCT/US2008/073872 WO2009026445A2 (en) | 2007-08-21 | 2008-08-21 | Methods and compositions for post-transcriptional gene silencing |
Publications (2)
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| JP2010536380A true JP2010536380A (ja) | 2010-12-02 |
| JP2010536380A5 JP2010536380A5 (enExample) | 2011-10-06 |
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| CA (1) | CA2697055A1 (enExample) |
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| MX339050B (es) * | 2009-12-18 | 2016-05-09 | Novartis Ag | Composiciones organicas para tratar las enfermedades relacionadas con hsf1. |
| US20120308642A1 (en) * | 2011-05-27 | 2012-12-06 | Xavier University Of Louisiana | Inhibiting hepatitis c viral replication with sirna combinations |
| US20140351961A1 (en) * | 2011-08-31 | 2014-11-27 | Alexzander A. Asea | Compositions and methods for treatment of metastatic cancer |
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| KR20080023768A (ko) * | 2000-03-30 | 2008-03-14 | 화이트헤드 인스티튜트 포 바이오메디칼 리서치 | Ｒｎａ 간섭의 ｒｎａ 서열 특이적인 매개체 |
| EP2305813A3 (en) * | 2002-11-14 | 2012-03-28 | Dharmacon, Inc. | Fuctional and hyperfunctional sirna |
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- 2008-08-21 AU AU2008288846A patent/AU2008288846A1/en not_active Abandoned
- 2008-08-21 EP EP08827769A patent/EP2185702A4/en not_active Withdrawn
- 2008-08-21 CA CA2697055A patent/CA2697055A1/en not_active Abandoned
- 2008-08-21 WO PCT/US2008/073872 patent/WO2009026445A2/en not_active Ceased
Non-Patent Citations (4)
| Title |
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| JPN6013009099; Ｂｉｏｃｈｅｍ Ｊ ｖｏｌ．３９１, 2005, ｐｐ．１８５-１９０ * |
| JPN6013009100; Ｂｒｉｔｉｓｈ Ｊｏｕｒｎａｌ ｏｆ Ｄｅｒｍａｔｏｌｏｇｙ ｖｏｌ．１５６, 200705, ｐｐ．１１８８-１１９５ * |
| JPN6013009102; ＴＨＥ ＪＯＵＲＮＡＬ ＯＦ ＢＩＯＬＯＧＩＣＡＬ ＣＨＥＭＩＳＴＲＹ ｖｏｌ．２８２ ｎｏ．２３, 200706, ｐｐ．１７２９７-１７３０５ * |
| JPN6013009105; Ｔｕｍｏｕｒ Ｂｉｏｌ ｖｏｌ．２７ ｎｏ．１, 2006, ｐｐ．１-１９ * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008288846A1 (en) | 2009-02-26 |
| CA2697055A1 (en) | 2009-02-26 |
| EP2185702A4 (en) | 2011-05-04 |
| WO2009026445A3 (en) | 2009-05-07 |
| EP2185702A2 (en) | 2010-05-19 |
| WO2009026445A2 (en) | 2009-02-26 |
| US20100186102A1 (en) | 2010-07-22 |
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