JP2010536372A5 - - Google Patents

Download PDF

Info

Publication number
JP2010536372A5
JP2010536372A5 JP2010521887A JP2010521887A JP2010536372A5 JP 2010536372 A5 JP2010536372 A5 JP 2010536372A5 JP 2010521887 A JP2010521887 A JP 2010521887A JP 2010521887 A JP2010521887 A JP 2010521887A JP 2010536372 A5 JP2010536372 A5 JP 2010536372A5
Authority
JP
Japan
Prior art keywords
mirna
urine
specific
sample
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010521887A
Other languages
English (en)
Japanese (ja)
Other versions
JP5416110B2 (ja
JP2010536372A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/009991 external-priority patent/WO2009025852A2/en
Publication of JP2010536372A publication Critical patent/JP2010536372A/ja
Publication of JP2010536372A5 publication Critical patent/JP2010536372A5/ja
Application granted granted Critical
Publication of JP5416110B2 publication Critical patent/JP5416110B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2010521887A 2007-08-22 2008-08-22 invivo細胞死を検出するためにmiRNAを使用する方法 Expired - Fee Related JP5416110B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96587107P 2007-08-22 2007-08-22
US60/965,871 2007-08-22
PCT/US2008/009991 WO2009025852A2 (en) 2007-08-22 2008-08-22 Methods of using mirna for detection of in vivo cell death

Publications (3)

Publication Number Publication Date
JP2010536372A JP2010536372A (ja) 2010-12-02
JP2010536372A5 true JP2010536372A5 (cg-RX-API-DMAC7.html) 2011-10-06
JP5416110B2 JP5416110B2 (ja) 2014-02-12

Family

ID=40378881

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010521887A Expired - Fee Related JP5416110B2 (ja) 2007-08-22 2008-08-22 invivo細胞死を検出するためにmiRNAを使用する方法

Country Status (16)

Country Link
US (4) US8486626B2 (cg-RX-API-DMAC7.html)
EP (2) EP2612926B1 (cg-RX-API-DMAC7.html)
JP (1) JP5416110B2 (cg-RX-API-DMAC7.html)
CN (2) CN105400868B (cg-RX-API-DMAC7.html)
AU (2) AU2008289447B2 (cg-RX-API-DMAC7.html)
CA (1) CA2696403C (cg-RX-API-DMAC7.html)
CY (1) CY1114111T1 (cg-RX-API-DMAC7.html)
DK (2) DK2195450T4 (cg-RX-API-DMAC7.html)
ES (2) ES2415245T5 (cg-RX-API-DMAC7.html)
HR (1) HRP20130618T1 (cg-RX-API-DMAC7.html)
HU (1) HUE019019T5 (cg-RX-API-DMAC7.html)
NO (1) NO2612926T3 (cg-RX-API-DMAC7.html)
PL (2) PL2195450T3 (cg-RX-API-DMAC7.html)
PT (2) PT2612926T (cg-RX-API-DMAC7.html)
TR (1) TR201802758T4 (cg-RX-API-DMAC7.html)
WO (1) WO2009025852A2 (cg-RX-API-DMAC7.html)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009132273A2 (en) * 2008-04-25 2009-10-29 Merck & Co., Inc. Microrna biomarkers of tissue injury
WO2010004562A2 (en) * 2008-07-09 2010-01-14 Rosetta Genomics Ltd. Methods and compositions for detecting colorectal cancer
US20100068711A1 (en) * 2008-07-18 2010-03-18 Xenomics, Inc. Methods of PCR-Based Detection of "Ultra Short" Nucleic Acid Sequences
US20120034608A1 (en) * 2009-04-14 2012-02-09 Merck Sharp & Dohme Corp. Microrna as a biomarker of pancreatic islet beta-cell engagement
CA2767616A1 (en) 2009-07-09 2011-01-13 The Scripps Research Institute Gene expression profiles associated with chronic allograft nephropathy
EP2496714B1 (en) 2009-11-04 2016-08-31 DiamiR, LLC Methods of using micro-rna from bodily fluids for diagnosis and monitoring of mild cognitive impairment
ES2821500T3 (es) 2009-11-06 2021-04-26 Univ Leland Stanford Junior Diagnóstico no invasivo del rechazo de injertos en pacientes con trasplante de órganos
SG185544A1 (en) * 2010-05-14 2012-12-28 Fluidigm Corp Nucleic acid isolation methods
JP6021893B2 (ja) * 2011-04-18 2016-11-09 ディアミール, エルエルシーDiamir, Llc 軽度認知機能障害(MCI)およびアルツハイマー病(AD)の早期検出ならびにモニタリングのために体液からのmiRNAを使用する方法
CN102188719B (zh) * 2011-05-12 2012-12-19 南方医科大学 EB病毒miR-BART3反义寡聚核苷酸在制备治疗鼻咽癌的药物中的应用
JP6154809B2 (ja) 2011-06-27 2017-06-28 エーザイ・アール・アンド・ディー・マネジメント株式会社 アルツハイマー病を示すマイクロrnaバイオマーカー
US20130040303A1 (en) * 2011-08-08 2013-02-14 Eugenia Wang Biomarker for Alzheimer's Disease and/or Mild Cognitive Impairment, and Use Thereof
WO2013043922A1 (en) * 2011-09-22 2013-03-28 ImmuMetrix, LLC Compositions and methods for analyzing heterogeneous samples
ITRM20110685A1 (it) 2011-12-23 2013-06-24 Internat Ct For Genetic En Gineering And Microrna per la rigenerazione cardiaca attraverso l induzione della proliferazione dei miociti cardiaci
US20130252835A1 (en) 2012-01-27 2013-09-26 Lian Chye Winston Koh Methods for profiling and quantitating cell-free rna
US20140087964A1 (en) * 2012-09-24 2014-03-27 University Of Virginia Patent Foundation Compositions and methods for detecting aberrant regulation, expression, and levels of hgh
EP2733219B1 (en) 2012-11-16 2017-09-20 Siemens Aktiengesellschaft Diagnostic miRNA markers for Alzheimer
EP2733220B1 (en) * 2012-11-16 2017-10-18 Siemens Aktiengesellschaft Novel miRNA as a diagnostic marker for Alzheimer's Disease
US10011873B2 (en) 2012-11-16 2018-07-03 Universitat Des Saarlandes Diagnostic miRNA markers for Parkinson disease
CN103045736B (zh) * 2012-12-20 2014-09-17 徐勇 唐氏综合征21号染色体miRNA差异表达图谱模型、构建方法及应用
CN103045596A (zh) * 2012-12-20 2013-04-17 徐勇 唐氏综合征21号染色体相关miRNA、基因、筛选方法和应用
EP2759602A1 (en) 2013-01-25 2014-07-30 Charité - Universitätsmedizin Berlin Non-invasive prenatal genetic diagnostic methods
EP3611262B1 (en) 2013-03-15 2020-11-11 Lineage Biosciences, Inc. Methods of sequencing the immune repertoire
ES2813699T3 (es) 2013-11-18 2021-03-24 Diamir Llc Métodos de uso de miARN de fluidos corporales para la detección y monitoreo de la enfermedad de Parkinson (PD)
US11104951B2 (en) 2014-05-22 2021-08-31 The Scripps Research Institute Molecular signatures for distinguishing liver transplant rejections or injuries
US10443100B2 (en) 2014-05-22 2019-10-15 The Scripps Research Institute Gene expression profiles associated with sub-clinical kidney transplant rejection
TWI813141B (zh) 2014-07-18 2023-08-21 香港中文大學 Dna混合物中之組織甲基化模式分析
WO2016187234A1 (en) 2015-05-18 2016-11-24 Karius, Inc. Compositions and methods for enriching populations of nucleic acids
WO2017019751A1 (en) 2015-07-27 2017-02-02 The Johns Hopkins University Method to use viral and host methylation markers for cervical cancer screening and triage in liquid prep, serum/plasma, and urine: pcr and sequencing based process methods
JP2018526021A (ja) * 2015-09-11 2018-09-13 コーニング インコーポレイテッド 血液試料からの核酸精製のための組成物及び方法
US10975436B2 (en) 2016-01-05 2021-04-13 Diamir, Llc Methods of using miRNA from bodily fluids for diagnosis and monitoring of neurodevelopmental disorders
WO2017165458A1 (en) 2016-03-21 2017-09-28 Diamir, Llc Methods of using mirnas from bodily fluids for detection and differentiation of neurodegenerative diseases
WO2018045359A1 (en) * 2016-09-02 2018-03-08 Karius, Inc. Detection and treatment of infection during pregnancy
CA3043709A1 (en) 2016-11-14 2018-05-17 Berg Llc Methods for treating parkinson's disease
IL315032A (en) 2016-11-30 2024-10-01 Univ Hong Kong Chinese Analysis of cell-free dna in urine and other samples
US10907211B1 (en) 2017-02-16 2021-02-02 Quantgene Inc. Methods and compositions for detecting cancer biomarkers in bodily fluids
US10781487B2 (en) 2017-07-24 2020-09-22 Diamir, Llc miRNA-based methods for detecting and monitoring aging
WO2020168118A1 (en) 2019-02-14 2020-08-20 Mirvie, Inc. Methods and systems for determining a pregnancy-related state of a subject
EP4052650A4 (en) * 2019-10-29 2023-12-06 National Cerebral and Cardiovascular Center SYSTEM TO SUPPORT THE TREATMENT OF STROKE
US11475981B2 (en) 2020-02-18 2022-10-18 Tempus Labs, Inc. Methods and systems for dynamic variant thresholding in a liquid biopsy assay
US11211147B2 (en) 2020-02-18 2021-12-28 Tempus Labs, Inc. Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing
US11211144B2 (en) 2020-02-18 2021-12-28 Tempus Labs, Inc. Methods and systems for refining copy number variation in a liquid biopsy assay

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5856088A (en) 1989-07-11 1999-01-05 Gen-Probe Incorporated Detection of human immunodeficiency virus type 1
US5168039A (en) 1990-09-28 1992-12-01 The Board Of Trustees Of The University Of Arkansas Repetitive DNA sequence specific for mycobacterium tuberculosis to be used for the diagnosis of tuberculosis
US6020124A (en) 1992-04-27 2000-02-01 Trustees Of Dartmouth College Detection of soluble gene sequences in biological fluids
CA2167693C (en) 1993-07-20 2007-01-30 Ulrich Bogdahn Melanoma-inhibiting protein
WO1995004140A1 (en) 1993-07-28 1995-02-09 Akzo Nobel N.V. Process for isolating nucleic acid from gram positive microorganisms
AU689815B2 (en) 1993-08-30 1998-04-09 Promega Corporation Nucleic acid purification compositions and methods
US5631130A (en) 1994-05-13 1997-05-20 Abbott Laboratories Materials and methods for the detection of Mycobacterium tuberculosis
CA2192364C (en) 1994-06-09 2009-01-20 Hans De Beenhouwer Method for the detection of the antibiotic resistance spectrum of mycobacterium species
US5731150A (en) 1995-11-01 1998-03-24 Chiron Diagnostic Corporation IS6110 based molecular detection of mycobacterium tuberculosis
US6027945A (en) 1997-01-21 2000-02-22 Promega Corporation Methods of isolating biological target materials using silica magnetic particles
US6492144B1 (en) 1997-05-30 2002-12-10 Diagen Corporation Methods for detection of nucleic acid sequences in urine
DK0920539T3 (da) 1997-05-30 2006-07-24 Xenomics Fremgangsmåder til detektion af nukleinsyresekvenser i urin
US20020119478A1 (en) 1997-05-30 2002-08-29 Diagen Corporation Methods for detection of nucleic acid sequences in urine
US5962665A (en) 1997-06-16 1999-10-05 Abbott Laboratories Nucleic acid primers and probes for detecting HIV-1 and HIV-2
US20060204989A1 (en) 1998-09-22 2006-09-14 Kopreski Michael S Comparative analysis of extracellular RNA species
US7196183B2 (en) 2001-08-31 2007-03-27 Innogenetics N.V. Hepatitis C virus genotype, and its use as prophylactic, therapeutic and diagnostic agent
US20040053264A1 (en) 2002-02-01 2004-03-18 Park Sung Sup Clinical panel assay using DNA chips
EP1771563A2 (en) * 2004-05-28 2007-04-11 Ambion, Inc. METHODS AND COMPOSITIONS INVOLVING MicroRNA
ITRM20050067A1 (it) 2005-02-17 2006-08-18 Istituto Naz Per Le Malattie I Metodo per la rivelazione di acidi nucleici virali o di origine virale nelle urine.
WO2006089203A2 (en) 2005-02-17 2006-08-24 Istituto Nazionale Per Le Malattie Infettive Irccs Lazzaro Spallanzani Compositions and methods for detecting viral specific nucleic acids in urine
US7914982B2 (en) 2005-02-17 2011-03-29 Trovagene, Inc. Methods for detecting pathogen specific nucleic acids in urine
CA2609636A1 (en) 2005-02-17 2006-08-24 Istituto Nazionale Per Le Malattie Infettive Irccs Lazzaro Spallanzani Compositions and methods for detecting pathogen specific nucleic acids in urine
ITRM20050068A1 (it) 2005-02-17 2006-08-18 Istituto Naz Per Le Malattie I Metodo per la rivelazione di acidi nucleici di agenti patogeni batterici o di parassiti nelle urine.
US20060292616A1 (en) * 2005-06-23 2006-12-28 U.S. Genomics, Inc. Single molecule miRNA-based disease diagnostic methods
DE102005059315A1 (de) * 2005-12-09 2007-06-14 Qiagen Gmbh Verfahren zur Anreicherung von kurzkettigen Nukleinsäuren
US20070202511A1 (en) * 2006-02-28 2007-08-30 Sigma-Aldrich Co. Methods and compositions for the rapid isolation of small RNA molecules
US20100068711A1 (en) 2008-07-18 2010-03-18 Xenomics, Inc. Methods of PCR-Based Detection of "Ultra Short" Nucleic Acid Sequences

Similar Documents

Publication Publication Date Title
JP5416110B2 (ja) invivo細胞死を検出するためにmiRNAを使用する方法
JP2010536372A5 (cg-RX-API-DMAC7.html)
CN106029900B (zh) 尿生物标志物群、基因表达特征及其使用方法
CN112980941B (zh) 一种诊断受试者是否患阿尔茨海默病的试剂盒及其用途
CN111733227A (zh) 特发性视神经炎诊断分子标记物circRNA、试剂盒及应用
KR102505618B1 (ko) 신장이식 후 항체 매개성 거부반응의 진단을 위한 소변 엑소좀 유래 miRNA 유전자 바이오마커 및 이의 용도
KR102545543B1 (ko) BK 바이러스 신병증의 진단을 위한 소변 엑소좀 유래 miRNA 유전자 바이오마커 및 이의 용도
WO2011004517A1 (ja) 標的核酸の検出方法、及び大腸癌の検査方法
CN105950705A (zh) 一组microRNAs在制备阿尔兹海默氏症诊断试剂或诊断试剂盒中的应用
KR20210024918A (ko) 신장이식 후 T 세포 매개성 거부반응의 진단을 위한 소변 엑소좀 유래 miRNA 유전자 바이오마커 및 이의 용도
HK1218767B (zh) 使用mirna检测体内细胞死亡情况的方法
JP5988022B2 (ja) ソラフェニブの効果予測方法
CN111363808B (zh) 一种与阿尔茨海默相关的生物标志物及其应用
WO2024200806A1 (en) Gene transcripts as signatures for tead-active cancer
CN111826437A (zh) 检测cyp46a1基因表达的产品在制备诊断非酒精性脂肪性肝病工具中的应用