JP2010534637A5 - - Google Patents
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- Publication number
- JP2010534637A5 JP2010534637A5 JP2010517418A JP2010517418A JP2010534637A5 JP 2010534637 A5 JP2010534637 A5 JP 2010534637A5 JP 2010517418 A JP2010517418 A JP 2010517418A JP 2010517418 A JP2010517418 A JP 2010517418A JP 2010534637 A5 JP2010534637 A5 JP 2010534637A5
- Authority
- JP
- Japan
- Prior art keywords
- polyol
- micronized
- composition
- mannitol
- erythritol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920005862 polyol Polymers 0.000 claims 21
- 150000003077 polyols Chemical class 0.000 claims 21
- 239000000203 mixture Substances 0.000 claims 12
- UNXHWFMMPAWVPI-QWWZWVQMSA-N D-Threitol Natural products OC[C@@H](O)[C@H](O)CO UNXHWFMMPAWVPI-QWWZWVQMSA-N 0.000 claims 11
- FBPFZTCFMRRESA-KAZBKCHUSA-N D-Mannitol Natural products OC[C@@H](O)[C@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KAZBKCHUSA-N 0.000 claims 6
- FBPFZTCFMRRESA-KVTDHHQDSA-N Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 6
- 239000000594 mannitol Substances 0.000 claims 6
- 235000010355 mannitol Nutrition 0.000 claims 6
- 239000004386 Erythritol Substances 0.000 claims 5
- 229940009714 Erythritol Drugs 0.000 claims 5
- 235000019414 erythritol Nutrition 0.000 claims 5
- SERLAGPUMNYUCK-DCUALPFSSA-N Isomalt Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O SERLAGPUMNYUCK-DCUALPFSSA-N 0.000 claims 4
- VQHSOMBJVWLPSR-WUJBLJFYSA-N Maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 claims 4
- 235000013305 food Nutrition 0.000 claims 4
- 239000007787 solid Substances 0.000 claims 4
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims 3
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims 3
- HEBKCHPVOIAQTA-SCDXWVJYSA-N Xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims 3
- 229960002675 Xylitol Drugs 0.000 claims 3
- 239000000905 isomalt Substances 0.000 claims 3
- 235000010439 isomalt Nutrition 0.000 claims 3
- 239000000845 maltitol Substances 0.000 claims 3
- 235000010449 maltitol Nutrition 0.000 claims 3
- 229940035436 maltitol Drugs 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 239000000600 sorbitol Substances 0.000 claims 3
- 235000010356 sorbitol Nutrition 0.000 claims 3
- 239000000811 xylitol Substances 0.000 claims 3
- 235000010447 xylitol Nutrition 0.000 claims 3
- HEBKCHPVOIAQTA-QWWZWVQMSA-N Arabitol Chemical compound OC[C@@H](O)C(O)[C@H](O)CO HEBKCHPVOIAQTA-QWWZWVQMSA-N 0.000 claims 2
- 229940112822 Chewing Gum Drugs 0.000 claims 2
- -1 altitol Chemical compound 0.000 claims 2
- 235000015218 chewing gum Nutrition 0.000 claims 2
- 239000002537 cosmetic Substances 0.000 claims 2
- 229960001855 mannitol Drugs 0.000 claims 2
- 239000002245 particle Substances 0.000 claims 2
- 229960002920 sorbitol Drugs 0.000 claims 2
- FBPFZTCFMRRESA-FBXFSONDSA-N (2R,3R,4S,5S)-hexane-1,2,3,4,5,6-hexol Chemical compound OC[C@H](O)[C@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-FBXFSONDSA-N 0.000 claims 1
- FBPFZTCFMRRESA-GUCUJZIJSA-N Galactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-GUCUJZIJSA-N 0.000 claims 1
- HEBKCHPVOIAQTA-ZXFHETKHSA-N Ribitol Chemical compound OC[C@H](O)[C@H](O)[C@H](O)CO HEBKCHPVOIAQTA-ZXFHETKHSA-N 0.000 claims 1
- 229910001873 dinitrogen Inorganic materials 0.000 claims 1
- 238000009826 distribution Methods 0.000 claims 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 1
- 239000000832 lactitol Substances 0.000 claims 1
- 235000010448 lactitol Nutrition 0.000 claims 1
- 229960003451 lactitol Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 1
- 238000003825 pressing Methods 0.000 claims 1
Claims (13)
- ２０〜６０μｍの粒径分布（ｄ５０）と、５ｓ／１００ｇ以下、好ましくは５ｓ／１００ｇ未満の流動度を有するマイクロナイズドポリオールであって、前記ポリオールが、マルチトール、イソマルト、マンニトール、ソルビトール、キシリトール、エリトリトール、およびそれらの２種以上の混合物から選択されるマイクロナイズドポリオール。
- ４０以上の圧縮性指数を有する、請求項１に記載のマイクロナイズドポリオール。
- 前記ポリオールがマンニトールである、請求項１に記載のマイクロナイズドポリオール。
- 前記ポリオールがエリトリトールである、請求項１に記載のマイクロナイズドポリオール。
- 前記ポリオールがマンニトールである、請求項２に記載のマイクロナイズドポリオール。
- 前記ポリオールがエリトリトールである、請求項２に記載のマイクロナイズドポリオール。
- 固体ポリオールをマイクロナイズする方法であって、その方法が次の工程：
ａ）固体ポリオールを取り込み、
ｂ）前記ポリオールをジェットミル内に供給しかつ窒素ガスを用いて圧力を加え、その際ジェットミル内に加えられる圧力が２〜６バールの範囲内であり、
ｃ）マイクロナイズドポリオールを捕集すること
を含み、
そして前記固体ポリオールが、エリトリトール、トレイトール、アラビニトール、キシリトール、リビトール、アリトール、アルトリトール、グリトール、ガラクチトール、マンニトール、ソルビトール、タリトール、マルチトール、イソマルチトール、イソマルト、ラクチトール、およびそれらの２種以上の混合物から選択される、上記方法。 - 前記固体ポリオールが、マルチトール、イソマルト、マンニトール、ソルビトール、キシリトール、エリトリトール、およびそれらの２種以上の混合物から選択される、請求項７に記載の方法。
- 前記マイクロナイズドポリオールが、２０〜６０μｍの範囲内の平均粒径と、５ｓ／１００ｇ以下、好ましくは５ｓ／１００ｇ未満の流動度を有する、請求項１に記載の方法。
- 請求項１に記載のマイクロナイズドポリオールを含有する、食品組成物、飼料組成物、化粧組成物または医薬組成物。
- 請求項２に記載のマイクロナイズドポリオールを含有する、食品組成物、飼料組成物、化粧組成物または医薬組成物。
- 前記食品がチューインガム組成物である、請求項１０に記載の食品組成物および／または医薬組成物。
- マイクロナイズドマンニトールを含み、そして製造の２４時間後に３５００ｇ以上、好ましくは４０００ｇより大きい硬さを有する、請求項１２に記載のチューインガム組成物。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07113374 | 2007-07-27 | ||
| EP07113374.8 | 2007-07-27 | ||
| PCT/EP2008/059834 WO2009016133A1 (en) | 2007-07-27 | 2008-07-25 | Micronization of polyols |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010534637A JP2010534637A (ja) | 2010-11-11 |
| JP2010534637A5 true JP2010534637A5 (ja) | 2011-07-21 |
| JP5547068B2 JP5547068B2 (ja) | 2014-07-09 |
Family
ID=38823526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010517418A Expired - Fee Related JP5547068B2 (ja) | 2007-07-27 | 2008-07-25 | ポリオールのマイクロナイゼーション |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20100255307A1 (ja) |
| EP (2) | EP2183262A1 (ja) |
| JP (1) | JP5547068B2 (ja) |
| CN (2) | CN101765606A (ja) |
| AU (1) | AU2008281850B2 (ja) |
| BR (1) | BRPI0814175A2 (ja) |
| CA (1) | CA2694280A1 (ja) |
| DK (1) | DK2264042T3 (ja) |
| ES (1) | ES2388494T3 (ja) |
| PL (1) | PL2264042T3 (ja) |
| RU (1) | RU2479587C2 (ja) |
| WO (1) | WO2009016133A1 (ja) |
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| AUPQ899700A0 (en) | 2000-07-25 | 2000-08-17 | Borody, Thomas Julius | Probiotic recolonisation therapy |
| AUPS088702A0 (en) * | 2002-03-04 | 2002-03-28 | Borody, Thomas Julius | Electrolyte purgative |
| PL2334202T3 (pl) * | 2008-09-04 | 2012-04-30 | Cargill Inc | Tabletkowanie erytrytolu |
| EP2228175B1 (de) * | 2009-03-12 | 2013-06-19 | Ferton Holding SA | Verwendung eines Pulvers oder Pulvergemisches zur Herstellung eines Mittels zur Pulverstrahlreinigung von Zahnoberflächen |
| US20120149784A1 (en) | 2009-08-18 | 2012-06-14 | Cargill ,Incorporated | Tabletting of erythritol and isomalt |
| JP5691219B2 (ja) * | 2010-03-30 | 2015-04-01 | 住友ベークライト株式会社 | 半導体封止用樹脂組成物の製造方法および粉砕装置 |
| CN102834020A (zh) | 2010-04-19 | 2012-12-19 | 卡吉尔公司 | 赤藓糖醇和异麦芽酮糖醇的锭剂 |
| RU2012153563A (ru) * | 2010-05-12 | 2014-06-20 | Карджилл, Инкорпорейтед | Подслащивающие композиции с уменьшенным горьким привкусом и способы их получения |
| JP5902677B2 (ja) | 2010-06-01 | 2016-04-13 | カーギル インコーポレイテッド | エリトリトール及びイソマルトの口腔内崩壊性錠剤 |
| US20130129806A1 (en) | 2010-07-27 | 2013-05-23 | Carglil Incorporated | Hard coating with erythritol |
| NZ618935A (en) | 2010-08-04 | 2014-03-28 | Karma Medical Prod Co Ltd | Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them |
| JP2013536694A (ja) | 2010-09-07 | 2013-09-26 | カーギル インコーポレイテッド | 凝固糖アルコール混合物 |
| WO2012069073A1 (de) * | 2010-11-12 | 2012-05-31 | La Prairie Group Ag | Kosmetische und/oder dermatologische zubereitungen enthaltend schneealgenextrakt |
| BR112013014827A2 (pt) | 2010-12-13 | 2016-10-04 | Antony Wettstein | formulações gástricas e colônicas e métodos para produzir e usar as mesmas |
| BR112013022927A2 (pt) | 2011-03-09 | 2016-12-06 | Univ Minnesota | composição, métodos para substituir ou suplementar ou modificar uma microbiota do cólon de um sujeito, e para tratar um sujeito, e, uso de uma composição |
| WO2013176774A1 (en) | 2012-05-25 | 2013-11-28 | Arizona Board Of Regents | Microbiome markers and therapies for autism spectrum disorders |
| CA2875681A1 (en) | 2012-06-04 | 2013-12-12 | Gaurav Agrawal | Compositions and methods for treating crohn's disease and related conditions and infections |
| EP2877163B1 (en) | 2012-07-27 | 2019-03-20 | Redhill Biopharma Ltd. | Formulations and methods of manufacturing formulations for use in colonic evacuation |
| EP2742806A1 (en) * | 2012-12-13 | 2014-06-18 | Südzucker Aktiengesellschaft | Process for reducing the stickiness of a chewing gum core composition to a surface of a processing machinery using isomalt |
| WO2014106962A1 (ko) * | 2013-01-07 | 2014-07-10 | 삼아제약 주식회사 | 향상된 용해도를 갖는 신규한 속용성 과립제형 |
| CA2910983C (en) | 2013-04-30 | 2021-11-02 | Thomas Julius Borody | Compositions and methods for treating microbiota-related psychotropic conditions and diseases |
| EA033518B1 (ru) | 2013-10-31 | 2019-10-31 | Suedzucker Ag Mannheim/Ochsenfurt | Жевательная резинка и способ ее получения |
| FR3023128B1 (fr) | 2014-07-01 | 2017-11-10 | Roquette Freres | Nouvelle composition edulcorante |
| CN104311610B (zh) * | 2014-11-06 | 2017-03-08 | 山东绿健生物技术有限公司 | 一种快速制备粒状乳糖醇的方法 |
| WO2016183577A1 (en) | 2015-05-14 | 2016-11-17 | Crestovo Llc | Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them |
| ES2909456T3 (es) | 2015-05-22 | 2022-05-06 | Univ Arizona State | Métodos para tratar el trastorno del espectro autista y síntomas asociados |
| WO2017053327A1 (en) | 2015-09-24 | 2017-03-30 | San Diego State University (Sdsu) Foundation , Dba San Diego State University Research Foundation | Antibacterial and protective bacteriophage formulations and methods for making and using them |
| CN105901339A (zh) * | 2016-04-26 | 2016-08-31 | 彭险峰 | 液体木糖醇及含有木糖醇的组合物在制备猪用饲料中的应用 |
| US20170360848A1 (en) | 2016-06-15 | 2017-12-21 | Arizona Board Of Regents On Behalf Of Arizona State University | Methods for treating autism spectrum disorder and associated symptoms |
| US10849936B2 (en) | 2016-07-01 | 2020-12-01 | Regents Of The University Of Minnesota | Compositions and methods for C. difficile treatment |
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| US10092601B2 (en) | 2016-10-11 | 2018-10-09 | Crestovo Holdings Llc | Compositions and methods for treating multiple sclerosis and related disorders |
| US11213549B2 (en) | 2016-10-11 | 2022-01-04 | Finch Therapeutics Holdings Llc | Compositions and method for treating primary sclerosing cholangitis and related disorders |
| US11026978B2 (en) | 2016-10-11 | 2021-06-08 | Finch Therapeutics Holdings Llc | Compositions and methods for treating multiple sclerosis and related disorders |
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| KR102582802B1 (ko) * | 2016-11-18 | 2023-10-06 | 페르틴 파르마 에이/에스 | 구강 케어 효과를 제공하는 방법 |
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| JP2020521760A (ja) | 2017-05-26 | 2020-07-27 | クレストヴォ・ホールディングス・エルエルシー | 糞便微生物ベースの治療剤を含む凍結乾燥組成物ならびにそれを製造および使用する方法 |
| CN111328284A (zh) | 2017-08-07 | 2020-06-23 | 芬奇治疗公司 | 用于维持和恢复健康的肠道屏障的组合物和方法 |
| US11052047B2 (en) | 2018-05-17 | 2021-07-06 | Fertin Pharma A/S | Oral tablet suitable for fast release of active pharmaceutical ingredients |
| US11058633B2 (en) | 2018-05-17 | 2021-07-13 | Fertin Pharma A/S | Disintegrating oral tablet suitable for active pharmaceutical ingredients |
| US11090263B2 (en) | 2018-05-22 | 2021-08-17 | Fertin Pharma A/S | Tableted chewing gum suitable for active pharmaceutical ingredients |
| US11096895B2 (en) | 2018-05-17 | 2021-08-24 | Fertin Pharma A/S | Oral tablet suitable for active pharmaceutical ingredients |
| US20190350858A1 (en) | 2018-05-17 | 2019-11-21 | Fertin Pharma A/S | Oral tablet for delivery of active ingredients to the gastrointestinal tract |
| US11135157B2 (en) | 2018-05-17 | 2021-10-05 | Fertin Pharma A/S | Oral tablet for delivery of active ingredients to the throat |
| US11058641B2 (en) | 2018-05-17 | 2021-07-13 | Fertin Pharma A/S | Oral tablet for taste masking of active ingredients |
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| US11096894B2 (en) | 2018-05-17 | 2021-08-24 | Fertin Pharma A/S | Oral tablet for induced saliva generation |
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| US11911419B2 (en) | 2018-09-27 | 2024-02-27 | Finch Therapeutics Holdings Llc | Compositions and methods for treating epilepsy and related disorders |
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-
2008
- 2008-07-25 EP EP08775360A patent/EP2183262A1/en not_active Withdrawn
- 2008-07-25 BR BRPI0814175-4A2A patent/BRPI0814175A2/pt not_active Application Discontinuation
- 2008-07-25 AU AU2008281850A patent/AU2008281850B2/en not_active Ceased
- 2008-07-25 RU RU2010107188/04A patent/RU2479587C2/ru not_active IP Right Cessation
- 2008-07-25 US US12/668,384 patent/US20100255307A1/en not_active Abandoned
- 2008-07-25 DK DK10175145.1T patent/DK2264042T3/da active
- 2008-07-25 EP EP10175145A patent/EP2264042B1/en not_active Not-in-force
- 2008-07-25 CN CN200880100640A patent/CN101765606A/zh active Pending
- 2008-07-25 JP JP2010517418A patent/JP5547068B2/ja not_active Expired - Fee Related
- 2008-07-25 CA CA2694280A patent/CA2694280A1/en not_active Abandoned
- 2008-07-25 CN CN201310650226.1A patent/CN103691530A/zh active Pending
- 2008-07-25 ES ES10175145T patent/ES2388494T3/es active Active
- 2008-07-25 PL PL10175145T patent/PL2264042T3/pl unknown
- 2008-07-25 WO PCT/EP2008/059834 patent/WO2009016133A1/en active Application Filing
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