JP2010534236A5 - - Google Patents
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- Publication number
- JP2010534236A5 JP2010534236A5 JP2010517503A JP2010517503A JP2010534236A5 JP 2010534236 A5 JP2010534236 A5 JP 2010534236A5 JP 2010517503 A JP2010517503 A JP 2010517503A JP 2010517503 A JP2010517503 A JP 2010517503A JP 2010534236 A5 JP2010534236 A5 JP 2010534236A5
- Authority
- JP
- Japan
- Prior art keywords
- medicament
- corm
- medicament according
- nsaid
- pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 claims 12
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 claims 4
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims 4
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical group O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims 1
- 208000024827 Alzheimer disease Diseases 0.000 claims 1
- 208000005189 Embolism Diseases 0.000 claims 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 208000002193 Pain Diseases 0.000 claims 1
- 208000034038 Pathologic Neovascularization Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 206010037660 Pyrexia Diseases 0.000 claims 1
- 208000007107 Stomach Ulcer Diseases 0.000 claims 1
- 208000001435 Thromboembolism Diseases 0.000 claims 1
- 229940072056 alginate Drugs 0.000 claims 1
- 235000010443 alginic acid Nutrition 0.000 claims 1
- 229920000615 alginic acid Polymers 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 210000001198 duodenum Anatomy 0.000 claims 1
- 201000005917 gastric ulcer Diseases 0.000 claims 1
- 230000004968 inflammatory condition Effects 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 150000002894 organic compounds Chemical class 0.000 claims 1
- 125000002524 organometallic group Chemical group 0.000 claims 1
- 208000003278 patent ductus arteriosus Diseases 0.000 claims 1
- 230000035939 shock Effects 0.000 claims 1
- 210000002784 stomach Anatomy 0.000 claims 1
- 208000011580 syndromic disease Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95165007P | 2007-07-24 | 2007-07-24 | |
| US60/951,650 | 2007-07-24 | ||
| PCT/IB2008/001945 WO2009013612A1 (en) | 2007-07-24 | 2008-07-24 | Prevention of gastric ulcery by carbon monoxide |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010534236A JP2010534236A (ja) | 2010-11-04 |
| JP2010534236A5 true JP2010534236A5 (https=) | 2012-11-22 |
| JP5563452B2 JP5563452B2 (ja) | 2014-07-30 |
Family
ID=40010478
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010517503A Expired - Fee Related JP5563452B2 (ja) | 2007-07-24 | 2008-07-24 | 一酸化炭素による胃潰瘍の予防 |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US20110038955A1 (https=) |
| EP (1) | EP2182961B1 (https=) |
| JP (1) | JP5563452B2 (https=) |
| AT (1) | ATE555795T1 (https=) |
| WO (1) | WO2009013612A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0111872D0 (en) | 2001-05-15 | 2001-07-04 | Northwick Park Inst For Medica | Therapeutic agents and methods |
| NZ534912A (en) | 2002-02-04 | 2007-08-31 | Alfama Investigacao E Desenvol | supramolecule aggregate comprising CO containing organometallic or transition metal complex and anti-inflammatory agent or biphosphonate phosphonate derivative |
| US7968605B2 (en) | 2002-02-04 | 2011-06-28 | ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. | Methods for treating inflammatory disease by administering aldehydes and derivatives thereof |
| GB2395432B (en) | 2002-11-20 | 2005-09-14 | Northwick Park Inst For Medica | Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs |
| AU2004262976A1 (en) * | 2003-08-04 | 2005-02-17 | Hemocorm Limited | Use of boranocarbonates for the therapeutic delivery of carbon monoxide |
| GB0601394D0 (en) | 2006-01-24 | 2006-03-01 | Hemocorm Ltd | Therapeutic delivery of carbon monoxide |
| US9512156B2 (en) | 2010-03-08 | 2016-12-06 | University Of Zurich | Carbon monoxide releasing rhenium compounds for medical use |
| US20130266668A1 (en) * | 2010-12-01 | 2013-10-10 | Virginia Commonwealth University | Use of hemoglobin effectors to increase the bioavailability of therapeutic gases |
| EP2699242B1 (en) | 2011-04-19 | 2017-11-01 | Alfama, Inc. | Carbon monoxide releasing molecules and uses thereof |
| JP6134710B2 (ja) | 2011-07-21 | 2017-05-24 | アルファーマ インコーポレイテッドＡｌｆａｍａ，Ｉｎｃ． | 一酸化ルテニウム放出分子およびその使用 |
| US9944669B2 (en) * | 2014-03-21 | 2018-04-17 | Universite Paris Est Creteil Val De Marne | Fumarate-CO-releasing molecule hybrids, their use in the treatment of inflammatory or cardiovascular diseases and their process of preparation |
| JP2018145248A (ja) * | 2017-03-02 | 2018-09-20 | 国立大学法人京都大学 | 無限配位高分子（ＩＣＰｓ）を用いた一酸化炭素放出材料 |
| EP3866773B1 (en) | 2018-10-16 | 2024-08-28 | Georgia State University Research Foundation, Inc. | Carbon monoxide prodrugs for the treatment of medical disorders |
| WO2022055991A1 (en) * | 2020-09-08 | 2022-03-17 | The Brigham And Women's Hospital, Inc. | Therapeutic carbon monoxide formulations |
| WO2025254524A1 (en) | 2024-06-05 | 2025-12-11 | Rijksuniversiteit Groningen | Carbon monoxide releasing therapeutic compounds and methods, products and uses related thereto |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3065250A (en) * | 1960-05-13 | 1962-11-20 | Hercules Powder Co Ltd | Nitrile-metal carbonyl complexes |
| US4569214A (en) * | 1983-09-14 | 1986-02-11 | Yang Yaw Kuen | Push button security lock |
| US4792452A (en) * | 1987-07-28 | 1988-12-20 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
| NZ534912A (en) * | 2002-02-04 | 2007-08-31 | Alfama Investigacao E Desenvol | supramolecule aggregate comprising CO containing organometallic or transition metal complex and anti-inflammatory agent or biphosphonate phosphonate derivative |
| CN1674942A (zh) * | 2002-06-21 | 2005-09-28 | 联邦高等教育系统匹兹堡大学 | 氧化氮、血红素加氧酶－1和血红素降解产物的药学用途 |
| US8148356B2 (en) * | 2005-08-24 | 2012-04-03 | Cumberland Pharmaceuticals, Inc. | Acetylcysteine composition and uses therefor |
| GB0601394D0 (en) * | 2006-01-24 | 2006-03-01 | Hemocorm Ltd | Therapeutic delivery of carbon monoxide |
| US20100196516A1 (en) * | 2007-04-24 | 2010-08-05 | ALFAMA-Investigacao e Desenvolvimento de produtos Farmaceuticos, Lda | Treatment of infections by carbon monoxide |
-
2008
- 2008-07-24 EP EP08788928A patent/EP2182961B1/en not_active Not-in-force
- 2008-07-24 AT AT08788928T patent/ATE555795T1/de active
- 2008-07-24 WO PCT/IB2008/001945 patent/WO2009013612A1/en not_active Ceased
- 2008-07-24 JP JP2010517503A patent/JP5563452B2/ja not_active Expired - Fee Related
- 2008-07-24 US US12/670,466 patent/US20110038955A1/en not_active Abandoned
-
2013
- 2013-10-11 US US14/052,551 patent/US20140212514A1/en not_active Abandoned
-
2016
- 2016-07-25 US US15/218,564 patent/US20170157168A1/en not_active Abandoned
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