JP2015129189A5 - - Google Patents
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- Publication number
- JP2015129189A5 JP2015129189A5 JP2015077340A JP2015077340A JP2015129189A5 JP 2015129189 A5 JP2015129189 A5 JP 2015129189A5 JP 2015077340 A JP2015077340 A JP 2015077340A JP 2015077340 A JP2015077340 A JP 2015077340A JP 2015129189 A5 JP2015129189 A5 JP 2015129189A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- mucositis
- ulcer
- inflammation
- substituent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 206010028116 Mucosal inflammation Diseases 0.000 claims 7
- 201000010927 Mucositis Diseases 0.000 claims 7
- 208000025865 Ulcer Diseases 0.000 claims 7
- 231100000397 ulcer Toxicity 0.000 claims 6
- 229920001661 Chitosan Polymers 0.000 claims 4
- 206010061218 Inflammation Diseases 0.000 claims 3
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 3
- 208000027418 Wounds and injury Diseases 0.000 claims 3
- 230000004054 inflammatory process Effects 0.000 claims 3
- 125000001424 substituent group Chemical group 0.000 claims 3
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 claims 2
- 206010012601 diabetes mellitus Diseases 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 208000017667 Chronic Disease Diseases 0.000 claims 1
- 208000011231 Crohn disease Diseases 0.000 claims 1
- 206010015150 Erythema Diseases 0.000 claims 1
- 208000037581 Persistent Infection Diseases 0.000 claims 1
- 208000025371 Taste disease Diseases 0.000 claims 1
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 claims 1
- 230000001154 acute effect Effects 0.000 claims 1
- 238000002512 chemotherapy Methods 0.000 claims 1
- 210000001072 colon Anatomy 0.000 claims 1
- 231100000321 erythema Toxicity 0.000 claims 1
- 210000003238 esophagus Anatomy 0.000 claims 1
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 1
- 230000035876 healing Effects 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 claims 1
- 210000002429 large intestine Anatomy 0.000 claims 1
- 210000000214 mouth Anatomy 0.000 claims 1
- 230000002093 peripheral effect Effects 0.000 claims 1
- 210000003800 pharynx Anatomy 0.000 claims 1
- 230000005855 radiation Effects 0.000 claims 1
- 238000001959 radiotherapy Methods 0.000 claims 1
- 210000000664 rectum Anatomy 0.000 claims 1
- 210000000813 small intestine Anatomy 0.000 claims 1
- 210000002784 stomach Anatomy 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 210000002105 tongue Anatomy 0.000 claims 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 claims 1
- 230000036269 ulceration Effects 0.000 claims 1
- 0 C*(C)C([C@](CCCNC(N)=N)N)=O Chemical compound C*(C)C([C@](CCCNC(N)=N)N)=O 0.000 description 2
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32143710P | 2010-04-06 | 2010-04-06 | |
| US61/321,437 | 2010-04-06 | ||
| US201161451430P | 2011-03-10 | 2011-03-10 | |
| US61/451,430 | 2011-03-10 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013503881A Division JP2013523827A (ja) | 2010-04-06 | 2011-04-06 | キトサン化合物を用いて創傷を処置するための方法および組成物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015237188A Division JP2016033164A (ja) | 2010-04-06 | 2015-12-04 | キトサン化合物を用いて創傷を処置するための方法および組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015129189A JP2015129189A (ja) | 2015-07-16 |
| JP2015129189A5 true JP2015129189A5 (https=) | 2016-01-28 |
| JP6000397B2 JP6000397B2 (ja) | 2016-09-28 |
Family
ID=44763261
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013503881A Pending JP2013523827A (ja) | 2010-04-06 | 2011-04-06 | キトサン化合物を用いて創傷を処置するための方法および組成物 |
| JP2015077340A Active JP6000397B2 (ja) | 2010-04-06 | 2015-04-06 | キトサン化合物を用いて創傷を処置するための方法および組成物 |
| JP2015237188A Withdrawn JP2016033164A (ja) | 2010-04-06 | 2015-12-04 | キトサン化合物を用いて創傷を処置するための方法および組成物 |
| JP2017194973A Withdrawn JP2017226706A (ja) | 2010-04-06 | 2017-10-05 | キトサン化合物を用いて創傷を処置するための方法および組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013503881A Pending JP2013523827A (ja) | 2010-04-06 | 2011-04-06 | キトサン化合物を用いて創傷を処置するための方法および組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015237188A Withdrawn JP2016033164A (ja) | 2010-04-06 | 2015-12-04 | キトサン化合物を用いて創傷を処置するための方法および組成物 |
| JP2017194973A Withdrawn JP2017226706A (ja) | 2010-04-06 | 2017-10-05 | キトサン化合物を用いて創傷を処置するための方法および組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US9439925B2 (https=) |
| EP (1) | EP2555760B1 (https=) |
| JP (4) | JP2013523827A (https=) |
| AU (1) | AU2011237682B2 (https=) |
| CA (1) | CA2795520C (https=) |
| ES (1) | ES2773017T3 (https=) |
| WO (1) | WO2011127144A1 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3144324A1 (en) | 2006-06-02 | 2017-03-22 | Synedgen, Inc. | Chitosan-derivative compounds and methods of controlling microbial populations |
| CA3004707C (en) | 2009-09-02 | 2022-05-31 | Synedgen Inc. | Methods and compositions for disrupting biofilm utilizing chitosan-derivative compounds |
| EP2555760B1 (en) | 2010-04-06 | 2019-10-16 | Synedgen, Inc. | Chitosan derivatives for the treatment of mucositis or ulceration |
| WO2013134129A2 (en) * | 2012-03-05 | 2013-09-12 | Synedgen, Inc. | Derivatized polyglucosamines for delivery of small molecules, peptides, and proteins |
| CN102755662B (zh) * | 2012-07-25 | 2014-01-08 | 福州乾正药业有限公司 | 一种复合壳聚糖凝胶膜及其制备方法 |
| WO2014047506A1 (en) | 2012-09-20 | 2014-03-27 | Synedgen, Inc. | Methods for treatment or prevention of damage resulting from radiation, trauma or shock |
| TWI478943B (zh) * | 2012-12-27 | 2015-04-01 | Ind Tech Res Inst | 高分子組成物用於製備具有抑制基質金屬蛋白酶之活性的功效的醫療器材或抑制劑的用途 |
| CN103893813B (zh) * | 2012-12-28 | 2018-04-17 | 财团法人工业技术研究院 | 高分子组合物与高分子材料 |
| JP6842916B2 (ja) | 2013-03-12 | 2021-03-17 | シネジェン， インコーポレイテッド | 非発酵性糖と組み合わせたポリグルコサミン誘導体の経口製剤 |
| WO2014172040A1 (en) * | 2013-03-15 | 2014-10-23 | Synedgen Inc. | Compositions and methods of use for wound healing |
| EP3034085B1 (en) * | 2013-08-13 | 2019-10-23 | Seikagaku Corporation | Drug containing cationized chitosan |
| US9259357B2 (en) | 2014-04-16 | 2016-02-16 | Loma Linda University | Composition, preparation, and use of chitosan shards for biomedical applications |
| CA2960998A1 (en) | 2014-09-11 | 2016-03-17 | Synedgen, Inc. | Compositions and methods of use thereof |
| KR20180066240A (ko) * | 2015-10-30 | 2018-06-18 | 크로마-파르마 게젤샤프트 엠.베.하. | 무균 수성 안과용 액제의 치료적 용도 |
| RU2741912C2 (ru) | 2015-10-30 | 2021-01-29 | Крома-Фарма Гезелльшафт М.Б.Х. | Применение в терапии стерильного водного офтальмологического раствора |
| WO2017161113A1 (en) * | 2016-03-16 | 2017-09-21 | Synedgen, Inc. | Compositions and methods of their use |
| CN108096182A (zh) * | 2016-11-25 | 2018-06-01 | 哈尔滨盈聚生物科技有限公司 | 一种基于绿色抗菌材料的妇科抗菌凝胶及其制备方法 |
| US10918699B2 (en) * | 2017-03-22 | 2021-02-16 | Michael C. Struck | Therapeutic treatment for neurotrophic keratopathy |
| WO2018202783A1 (en) | 2017-05-03 | 2018-11-08 | Croma-Pharma Gmbh | Sterile aqueous ophthalmic solution containing n-(n-acetylcysteinyl)-chitosan for treating non-infectious corneal disorders |
| TWI633888B (zh) * | 2017-10-03 | 2018-09-01 | 黃琮瑋 | 醣類物質用於製備改善嗅覺功能的藥物之用途 |
| CN107970269A (zh) * | 2017-12-30 | 2018-05-01 | 广州润虹医药科技股份有限公司 | 一种含有壳聚糖的口腔溃疡膜及其制备方法 |
| RU2697869C1 (ru) * | 2018-04-28 | 2019-08-21 | федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет) | Фармацевтическая субстанция для лечения инфицированных ран различного генеза |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
| WO2021221656A1 (en) | 2020-04-30 | 2021-11-04 | Synedgen, Inc. | Compositions and methods of use thereof |
| EP4406542A1 (en) | 2023-01-26 | 2024-07-31 | BioKuris | Treatment of gut inflammatory diseases |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4409205A (en) * | 1979-03-05 | 1983-10-11 | Cooper Laboratories, Inc. | Ophthalmic solution |
| US4532134A (en) | 1981-04-06 | 1985-07-30 | Malette William Graham | Method of achieving hemostasis, inhibiting fibroplasia, and promoting tissue regeneration in a tissue wound |
| JPH09510961A (ja) * | 1994-01-14 | 1997-11-04 | ジュニア シャヒニアン，リー | 持続性および長期間の角膜鎮痛の方法 |
| US7214202B1 (en) | 1997-07-28 | 2007-05-08 | Kci Licensing, Inc. | Therapeutic apparatus for treating ulcers |
| EP1061937A1 (en) | 1998-03-10 | 2000-12-27 | University Of Southern California | Improved radiation therapy methods |
| BR9912627A (pt) | 1998-07-30 | 2002-02-13 | Nutriceuticals Inc E | Composição em suspensão lìquida estável, e, processos para preparação e uso da mesma e para tratamento de peso e de colesterol |
| US6114382A (en) | 1998-11-11 | 2000-09-05 | Moretti; Itagiba G. | Methods for treating inflammatory bowel disease |
| DE69828451T2 (de) * | 1998-11-20 | 2006-01-12 | Laboratoire Medidom S.A. | Wässrige ophthalmische formulierungen mit chitosan |
| US6962151B1 (en) | 1999-11-05 | 2005-11-08 | Pari GmbH Spezialisten für effektive Inhalation | Inhalation nebulizer |
| JP2003012702A (ja) * | 2001-04-24 | 2003-01-15 | Sankyo Co Ltd | 低分子キトサンの製造方法 |
| ATE481110T1 (de) | 2002-07-16 | 2010-10-15 | Biosyntech Canada Inc | Zusammensetzung für die herstellung zellkompatibler, injizierbarer, selbstgelierender chitosan lösungen zum einkapseln und verabreichen von lebenden zellen oderbiologisch aktiven faktoren |
| GB2393120A (en) | 2002-09-18 | 2004-03-24 | Johnson & Johnson Medical Ltd | Compositions for wound treatment |
| GB0302741D0 (en) | 2003-02-06 | 2003-03-12 | Advanced Biopolymers As | Use |
| GB0303085D0 (en) | 2003-02-11 | 2003-03-19 | Pfizer Ltd | Model |
| MX2007001018A (es) | 2004-07-26 | 2007-08-07 | Kci Licensing Inc | Metodo para recubrir un sustrato con un agente antimicrobiano y un producto formado por el mismo. |
| CN1965650A (zh) | 2005-11-14 | 2007-05-23 | 陈祖辉 | 多元金属离子螯合的甲壳素绿色抗菌剂 |
| EP3144324A1 (en) | 2006-06-02 | 2017-03-22 | Synedgen, Inc. | Chitosan-derivative compounds and methods of controlling microbial populations |
| KR20200075044A (ko) | 2008-01-22 | 2020-06-25 | 아라임 파마슈티칼즈, 인크. | 조직 손상 관련 질환 및 장애를 예방 및 치료하기 위한 조직 보호 펩티드 및 펩티드 유사체 |
| CA2723848C (en) * | 2008-05-09 | 2013-01-08 | Regenics As | Method of making salmon egg cytoplasmic extracts and use for increasing collagen production in skin |
| WO2010021930A1 (en) * | 2008-08-16 | 2010-02-25 | Synedgen, Inc. | Prevention and treatment of mrsa infections with chitosan-derivatives |
| WO2010025267A2 (en) | 2008-08-29 | 2010-03-04 | The General Hospital Corporation | Methods of modulating gastrointestinal tract flora levels with alkaline phosphatase |
| EP2364153B1 (en) | 2008-11-12 | 2015-05-06 | Synedgen, Inc. | Chitosan derivatives to optimize animal weight gain |
| US8916542B2 (en) | 2008-11-12 | 2014-12-23 | Synedgen, Inc. | Chitosan derivatives, compositions and related methods of use |
| EP2391387A1 (en) | 2009-01-29 | 2011-12-07 | Synedgen, Inc. | Nucleic acid delivery using modified chitosans |
| CN102458419A (zh) | 2009-06-10 | 2012-05-16 | 埃克塞拉医学有限责任公司 | 组合物用于治疗粘膜炎的用途 |
| CA3004707C (en) * | 2009-09-02 | 2022-05-31 | Synedgen Inc. | Methods and compositions for disrupting biofilm utilizing chitosan-derivative compounds |
| JP2013503897A (ja) | 2009-09-02 | 2013-02-04 | シネジェン， インコーポレイテッド | キトサン誘導体化合物を用いる口腔ケア方法および組成物 |
| EP2555760B1 (en) | 2010-04-06 | 2019-10-16 | Synedgen, Inc. | Chitosan derivatives for the treatment of mucositis or ulceration |
| AU2012279209A1 (en) | 2011-07-01 | 2014-01-23 | Synedgen, Inc. | Methods and compositions of reducing and preventing bacterial growth and the formation of biofilm on a surface utilizing chitosan-derivative compounds |
| US8735571B2 (en) | 2011-12-22 | 2014-05-27 | Agenta Biotechnologies, Inc. | Composition, preparation, and use of dense chitosan membrane materials |
| WO2013134129A2 (en) | 2012-03-05 | 2013-09-12 | Synedgen, Inc. | Derivatized polyglucosamines for delivery of small molecules, peptides, and proteins |
| WO2014047506A1 (en) | 2012-09-20 | 2014-03-27 | Synedgen, Inc. | Methods for treatment or prevention of damage resulting from radiation, trauma or shock |
| JP6842916B2 (ja) | 2013-03-12 | 2021-03-17 | シネジェン， インコーポレイテッド | 非発酵性糖と組み合わせたポリグルコサミン誘導体の経口製剤 |
| WO2014172040A1 (en) | 2013-03-15 | 2014-10-23 | Synedgen Inc. | Compositions and methods of use for wound healing |
| CA2960998A1 (en) | 2014-09-11 | 2016-03-17 | Synedgen, Inc. | Compositions and methods of use thereof |
| WO2018202783A1 (en) | 2017-05-03 | 2018-11-08 | Croma-Pharma Gmbh | Sterile aqueous ophthalmic solution containing n-(n-acetylcysteinyl)-chitosan for treating non-infectious corneal disorders |
| US11390408B2 (en) | 2020-11-24 | 2022-07-19 | Axon Llc | System and method for applying tubular bands to containers utilizing angled band ejection |
-
2011
- 2011-04-06 EP EP11766639.6A patent/EP2555760B1/en active Active
- 2011-04-06 US US13/639,560 patent/US9439925B2/en active Active
- 2011-04-06 JP JP2013503881A patent/JP2013523827A/ja active Pending
- 2011-04-06 AU AU2011237682A patent/AU2011237682B2/en active Active
- 2011-04-06 ES ES11766639T patent/ES2773017T3/es active Active
- 2011-04-06 WO PCT/US2011/031385 patent/WO2011127144A1/en not_active Ceased
- 2011-04-06 CA CA2795520A patent/CA2795520C/en active Active
-
2015
- 2015-04-06 JP JP2015077340A patent/JP6000397B2/ja active Active
- 2015-12-04 JP JP2015237188A patent/JP2016033164A/ja not_active Withdrawn
-
2016
- 2016-06-03 US US15/173,218 patent/US20170119810A1/en not_active Abandoned
-
2017
- 2017-10-05 JP JP2017194973A patent/JP2017226706A/ja not_active Withdrawn
-
2018
- 2018-03-16 US US15/923,696 patent/US11717532B2/en active Active
-
2023
- 2023-06-13 US US18/333,968 patent/US20240197769A1/en not_active Abandoned
-
2024
- 2024-12-20 US US18/989,494 patent/US20250345355A1/en active Pending
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