ATE555795T1 - Verhinderung von magengeschwüren mit kohlenmonoxid - Google Patents

Verhinderung von magengeschwüren mit kohlenmonoxid

Info

Publication number
ATE555795T1
ATE555795T1 AT08788928T AT08788928T ATE555795T1 AT E555795 T1 ATE555795 T1 AT E555795T1 AT 08788928 T AT08788928 T AT 08788928T AT 08788928 T AT08788928 T AT 08788928T AT E555795 T1 ATE555795 T1 AT E555795T1
Authority
AT
Austria
Prior art keywords
carbon monoxide
stomach ulcer
preventing stomach
preventing
ulcer
Prior art date
Application number
AT08788928T
Other languages
German (de)
English (en)
Inventor
Sandra Rodrigues
Joaeo Seixas
Bruno Guerreiro
Nuno Pereira
Carlos Romco
Werner Haas
Isabel Goncalves
Original Assignee
Alfama Investigacao E Desenvolvimento De Productos Farmaceuticos Lda
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfama Investigacao E Desenvolvimento De Productos Farmaceuticos Lda filed Critical Alfama Investigacao E Desenvolvimento De Productos Farmaceuticos Lda
Application granted granted Critical
Publication of ATE555795T1 publication Critical patent/ATE555795T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT08788928T 2007-07-24 2008-07-24 Verhinderung von magengeschwüren mit kohlenmonoxid ATE555795T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95165007P 2007-07-24 2007-07-24
PCT/IB2008/001945 WO2009013612A1 (en) 2007-07-24 2008-07-24 Prevention of gastric ulcery by carbon monoxide

Publications (1)

Publication Number Publication Date
ATE555795T1 true ATE555795T1 (de) 2012-05-15

Family

ID=40010478

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08788928T ATE555795T1 (de) 2007-07-24 2008-07-24 Verhinderung von magengeschwüren mit kohlenmonoxid

Country Status (5)

Country Link
US (3) US20110038955A1 (https=)
EP (1) EP2182961B1 (https=)
JP (1) JP5563452B2 (https=)
AT (1) ATE555795T1 (https=)
WO (1) WO2009013612A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0111872D0 (en) 2001-05-15 2001-07-04 Northwick Park Inst For Medica Therapeutic agents and methods
US7011854B2 (en) 2002-02-04 2006-03-14 Alfama-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda Method for treating a mammal by administration of a compound having the ability to release CO, compounds having the ability to release CO and pharmaceutical compositions thereof
US7968605B2 (en) 2002-02-04 2011-06-28 ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
GB2395432B (en) 2002-11-20 2005-09-14 Northwick Park Inst For Medica Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs
CA2534415A1 (en) * 2003-08-04 2005-02-17 Northwick Park Institute For Medical Research Therapeutic delivery of carbon monoxide
GB0601394D0 (en) 2006-01-24 2006-03-01 Hemocorm Ltd Therapeutic delivery of carbon monoxide
CA2792319A1 (en) 2010-03-08 2011-09-15 University Of Zuerich Carbon monoxide releasing rhenium compounds for medical use
US20130266668A1 (en) * 2010-12-01 2013-10-10 Virginia Commonwealth University Use of hemoglobin effectors to increase the bioavailability of therapeutic gases
US9163044B2 (en) 2011-04-19 2015-10-20 Alfama, Inc. Carbon monoxide releasing molecules and uses thereof
ES2628634T3 (es) 2011-07-21 2017-08-03 Alfama, Inc. Moléculas liberadoras de monóxido de carbono-rutenio y usos de las mismas
ES2718548T3 (es) * 2014-03-21 2019-07-02 Univ Paris Val De Marne Híbridos de molécula de liberación de CO-fumarato, su utilización en el tratamiento de enfermedades inflamatorias o cardiovasculares y su procedimiento de preparación
JP2018145248A (ja) * 2017-03-02 2018-09-20 国立大学法人京都大学 無限配位高分子（ＩＣＰｓ）を用いた一酸化炭素放出材料
EP3866773B1 (en) 2018-10-16 2024-08-28 Georgia State University Research Foundation, Inc. Carbon monoxide prodrugs for the treatment of medical disorders
US20230398141A1 (en) * 2020-09-08 2023-12-14 The Brigham And Women's Hospital, Inc. Therapeutic carbon monoxide formulations
WO2025254524A1 (en) 2024-06-05 2025-12-11 Rijksuniversiteit Groningen Carbon monoxide releasing therapeutic compounds and methods, products and uses related thereto

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3065250A (en) * 1960-05-13 1962-11-20 Hercules Powder Co Ltd Nitrile-metal carbonyl complexes
US4569214A (en) * 1983-09-14 1986-02-11 Yang Yaw Kuen Push button security lock
US4792452A (en) * 1987-07-28 1988-12-20 E. R. Squibb & Sons, Inc. Controlled release formulation
US7011854B2 (en) * 2002-02-04 2006-03-14 Alfama-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda Method for treating a mammal by administration of a compound having the ability to release CO, compounds having the ability to release CO and pharmaceutical compositions thereof
WO2004000368A1 (en) * 2002-06-21 2003-12-31 University Of Pittsburgh Of The Commonwealth System Of Higher Education Pharmaceutical use of nitric oxide, heme oxygenase-1 and products of heme degradation
US8148356B2 (en) * 2005-08-24 2012-04-03 Cumberland Pharmaceuticals, Inc. Acetylcysteine composition and uses therefor
GB0601394D0 (en) * 2006-01-24 2006-03-01 Hemocorm Ltd Therapeutic delivery of carbon monoxide
WO2008130261A1 (en) * 2007-04-24 2008-10-30 Alfama - Investigaçao E Desenvolvimento De Produtos Farmaceuticos Lda. Treatment of infections by carbon monoxide

Also Published As

Publication number Publication date
JP5563452B2 (ja) 2014-07-30
US20170157168A1 (en) 2017-06-08
EP2182961B1 (en) 2012-05-02
US20110038955A1 (en) 2011-02-17
EP2182961A1 (en) 2010-05-12
JP2010534236A (ja) 2010-11-04
WO2009013612A1 (en) 2009-01-29
US20140212514A1 (en) 2014-07-31

Similar Documents

Publication Publication Date Title
ATE555795T1 (de) Verhinderung von magengeschwüren mit kohlenmonoxid
EA200970737A1 (ru) Оксабициклогептаны и оксабициклогептены, их получение и применение
IS8829A (is) Hvatar fyrir tvíþætta oxun á ammóníaki og kolmónoxíð með litla eða enga myndun á köfnunarefnisoxíði.
EP2350476A4 (en) TURNING ARRANGEMENT AND CLIP HOOK COMBINATION AND THIS JEWEL
EP2145646A4 (en) oxygenate
EA200900441A1 (ru) Способы и интермедиаты для получения ингибиторов интегразы
UY29853A1 (es) Derivados de diacilindazol como inhibidores de lipasas y fosfolipasas-
EP2210640A4 (en) OXYGEN
EP2321569A4 (en) PORTABLE LIGHTING DEVICES
BR122013008865B8 (pt) adenovírus oncolítico de replicação competente
EA201070786A1 (ru) Бензофуропиримидиноны
CY1113102T1 (el) Ενωσεις φαινυλπροπιοναμιδιου και η χρηση αυτων
EP2301525A4 (en) TOPICAL IBUPROFEN FORMULATION
EA201170288A1 (ru) Оксабициклогептаны и оксабициклогептены, их получение и применение
ATE554066T1 (de) Entzündungshemmende substituierte cyclobutendionverbindungen
CU23862B1 (es) Dispositivo para encender y operar quemadores en la gasificación de combustibles con carbono
CY1116852T1 (el) Δισκια διπλης στιβαδας τα οποια περιεχουν ελβιτεγραβιρη, κοβισιστατη, εμτρισιταβινη και τενοφοβιρη
TW200800987A (en) Triazolopyridine derivatives as inhibitors of lipases and phospholipases
PL2139455T3 (pl) Tabletka o ulepszonej stabilności zawierająca co najmniej dwie substancje czynne
EA200700982A1 (ru) Производные хинолина и изохинолина, замещённые в 5-ом положении, способ их получения и их применение в качестве противовоспалительных средств
EP2309563A4 (en) COMPOSITION AND COMPOSITION USING LIGHT-EMITTING ITEM
EP2181065A4 (en) PARTIAL OXIDATION OF HYDROCARBONS
UA113841C2 (xx) Сірководневі похідні нестероїдних протизапальних лікарських засобів
DE602006019873D1 (de) Filmstrukturen mit verbesserter sauerstoffübertragung
DK1796698T3 (da) Stamme af lactobacillus acidophilus med analgetiske egenskaber i det gastrointestinale system