JP2010534191A5 - - Google Patents
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- JP2010534191A5 JP2010534191A5 JP2010503072A JP2010503072A JP2010534191A5 JP 2010534191 A5 JP2010534191 A5 JP 2010534191A5 JP 2010503072 A JP2010503072 A JP 2010503072A JP 2010503072 A JP2010503072 A JP 2010503072A JP 2010534191 A5 JP2010534191 A5 JP 2010534191A5
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- JP
- Japan
- Prior art keywords
- seq
- isolated peptide
- item
- antibody
- abcb5
- Prior art date
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- OUPZKGBUJRBPGC-HLTSFMKQSA-N 1,5-bis[[(2r)-oxiran-2-yl]methyl]-3-[[(2s)-oxiran-2-yl]methyl]-1,3,5-triazinane-2,4,6-trione Chemical compound O=C1N(C[C@H]2OC2)C(=O)N(C[C@H]2OC2)C(=O)N1C[C@H]1CO1 OUPZKGBUJRBPGC-HLTSFMKQSA-N 0.000 description 1
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92312807P | 2007-04-12 | 2007-04-12 | |
| US60/923,128 | 2007-04-12 | ||
| US705907P | 2007-12-11 | 2007-12-11 | |
| US61/007,059 | 2007-12-11 | ||
| PCT/US2008/004715 WO2008127656A1 (en) | 2007-04-12 | 2008-04-11 | Targeting abcb5 for cancer therapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014090150A Division JP2014133770A (ja) | 2007-04-12 | 2014-04-24 | 癌療法のためのａｂｃｂ５標的化 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010534191A JP2010534191A (ja) | 2010-11-04 |
| JP2010534191A5 true JP2010534191A5 (enExample) | 2011-05-06 |
| JP5889527B2 JP5889527B2 (ja) | 2016-03-22 |
Family
ID=39661432
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010503072A Active JP5889527B2 (ja) | 2007-04-12 | 2008-04-11 | 癌療法のためのａｂｃｂ５標的化 |
| JP2014090150A Withdrawn JP2014133770A (ja) | 2007-04-12 | 2014-04-24 | 癌療法のためのａｂｃｂ５標的化 |
| JP2016153402A Active JP6268237B2 (ja) | 2007-04-12 | 2016-08-04 | 癌療法のためのａｂｃｂ５標的化 |
| JP2017247931A Active JP6530044B2 (ja) | 2007-04-12 | 2017-12-25 | 癌療法のためのａｂｃｂ５標的化 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014090150A Withdrawn JP2014133770A (ja) | 2007-04-12 | 2014-04-24 | 癌療法のためのａｂｃｂ５標的化 |
| JP2016153402A Active JP6268237B2 (ja) | 2007-04-12 | 2016-08-04 | 癌療法のためのａｂｃｂ５標的化 |
| JP2017247931A Active JP6530044B2 (ja) | 2007-04-12 | 2017-12-25 | 癌療法のためのａｂｃｂ５標的化 |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US7928202B2 (enExample) |
| EP (3) | EP2644205B1 (enExample) |
| JP (4) | JP5889527B2 (enExample) |
| AU (1) | AU2008239633B2 (enExample) |
| CA (1) | CA2718573C (enExample) |
| CY (2) | CY1116823T1 (enExample) |
| DK (2) | DK2644205T3 (enExample) |
| ES (2) | ES2547016T3 (enExample) |
| HR (2) | HRP20150934T1 (enExample) |
| HU (2) | HUE027593T2 (enExample) |
| LT (1) | LT2644205T (enExample) |
| PL (2) | PL2155248T3 (enExample) |
| PT (2) | PT2644205T (enExample) |
| SI (2) | SI2155248T1 (enExample) |
| WO (1) | WO2008127656A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60140868D1 (de) * | 2000-06-05 | 2010-02-04 | Brigham & Womens Hospital | Für ein homologes des humanen, für mehrfachresistenz verantwortlichen, p-glykoproteins auf chromosom 7p15-21 kodierendes gen sowie verwendungen dafür |
| PL2772535T3 (pl) * | 2006-05-31 | 2022-09-05 | Children's Medical Center Corporation | Mezenchymalne komórki macierzyste ABC5 dodatnie jako immunomodulatory |
| EP2644205B1 (en) | 2007-04-12 | 2018-06-13 | The Brigham and Women's Hospital, Inc. | Targeting ABCB5 for cancer therapy |
| US11542328B2 (en) | 2008-11-14 | 2023-01-03 | The Brigham And Women's Hospital, Inc. | Therapeutic and diagnostic methods relating to cancer stem cells |
| EP3978928A1 (en) | 2008-11-14 | 2022-04-06 | The Brigham and Women's Hospital, Inc. | Therapeutic and diagnostic methods relating to cancer stem cells |
| WO2010065711A1 (en) * | 2008-12-04 | 2010-06-10 | Adimab, Inc. | An abcb5 epitope and antibodies thereto for the treatment of cancer |
| US20110280862A1 (en) * | 2010-05-14 | 2011-11-17 | The University Of Hong Kong | Gep and drug transporter regulation, cancer therapy and prognosis |
| ES2860573T3 (es) | 2013-02-19 | 2021-10-05 | Childrens Medical Center | Células madre ABCB5(+) para el tratamiento de enfermedades oculares |
| CN105517587B (zh) | 2013-05-10 | 2019-02-19 | 儿童医学中心公司 | 伤口愈合与组织工程 |
| US9177410B2 (en) | 2013-08-09 | 2015-11-03 | Ayla Mandel | System and method for creating avatars or animated sequences using human body features extracted from a still image |
| US20180134771A1 (en) * | 2015-05-07 | 2018-05-17 | Bioxcel Corporation | Novel immunomodulatory therapeutic strategies targeting tumors in cancer |
| AU2016293674B2 (en) | 2015-07-16 | 2019-11-21 | Bioxcel Therapeutics, Inc. | A novel approach for treatment of cancer using immunomodulation |
| WO2019210109A1 (en) * | 2018-04-25 | 2019-10-31 | Children's Medical Center Corporation | Abcb5 ligands and substrates |
| US12014835B2 (en) | 2020-02-19 | 2024-06-18 | Vanderbilt University | Methods for evaluating therapeutic benefit of combination therapies |
| JP2023522047A (ja) * | 2020-04-15 | 2023-05-26 | ザ チルドレンズ メディカル センター コーポレーション | 多形性膠芽腫におけるａｂｃｂ５の標的化 |
| US20230203153A1 (en) * | 2020-04-30 | 2023-06-29 | Children's Medical Center Corporation | Antibodies specific to abcb5 and uses thereof |
| CN116836291B (zh) * | 2023-08-25 | 2023-11-07 | 宝船生物医药科技(上海)有限公司 | 抗cd47-cldn18.2双特异性抗体的抗独特型抗体及其制备方法和应用 |
Family Cites Families (105)
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|---|---|---|---|---|
| US565354A (en) | 1896-08-04 | James h | ||
| US3854480A (en) | 1969-04-01 | 1974-12-17 | Alza Corp | Drug-delivery system |
| USRE30985E (en) | 1978-01-01 | 1982-06-29 | Serum-free cell culture media | |
| WO1980001139A1 (en) | 1978-12-06 | 1980-06-12 | Svedman Paul | Device for treating tissues,for example skin |
| US4355023A (en) | 1980-09-30 | 1982-10-19 | The Massachusetts General Hospital | Antibody fragment compositions and process |
| US4675189A (en) | 1980-11-18 | 1987-06-23 | Syntex (U.S.A.) Inc. | Microencapsulation of water soluble active polypeptides |
| US4470925A (en) | 1982-05-05 | 1984-09-11 | E. I. Du Pont De Nemours And Company | Immunoglobulin half-molecules and process for producing hybrid antibodies |
| US4462334A (en) | 1982-08-19 | 1984-07-31 | Kim Ho K | Solar animal structure |
| AT379688B (de) | 1982-11-22 | 1986-02-10 | List Hans | Sensorelement zur bestimmung des o2-gehaltes einer probe |
| US4452775A (en) | 1982-12-03 | 1984-06-05 | Syntex (U.S.A.) Inc. | Cholesterol matrix delivery system for sustained release of macromolecules |
| US4560655A (en) | 1982-12-16 | 1985-12-24 | Immunex Corporation | Serum-free cell culture medium and process for making same |
| US4657866A (en) | 1982-12-21 | 1987-04-14 | Sudhir Kumar | Serum-free, synthetic, completely chemically defined tissue culture media |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4767704A (en) | 1983-10-07 | 1988-08-30 | Columbia University In The City Of New York | Protein-free culture medium |
| EP0174810B1 (en) | 1984-09-10 | 1993-07-21 | HSC Research Development Corporation | Multidrug resistance in mammalian cell lines and isolation of determinant glycoprotein dna |
| US4837306A (en) | 1985-02-25 | 1989-06-06 | The Ontario Cancer Institute | Method for selecting hybridomas producing antibodies specific to the P-glycoprotein cell suface antigen and a cDNA clone encoding the C-terminal portion of the antigen |
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