JP2010530001A - 硫化物単独または一酸化窒素との組み合わせを含む組成物およびその使用 - Google Patents

硫化物単独または一酸化窒素との組み合わせを含む組成物およびその使用 Download PDF

Info

Publication number
JP2010530001A
JP2010530001A JP2010512395A JP2010512395A JP2010530001A JP 2010530001 A JP2010530001 A JP 2010530001A JP 2010512395 A JP2010512395 A JP 2010512395A JP 2010512395 A JP2010512395 A JP 2010512395A JP 2010530001 A JP2010530001 A JP 2010530001A
Authority
JP
Japan
Prior art keywords
sulfide
nitric oxide
angiogenesis
administered
animal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010512395A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010530001A5 (enExample
Inventor
サボ チャバ
Original Assignee
イカリア, インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by イカリア, インコーポレイテッド filed Critical イカリア, インコーポレイテッド
Publication of JP2010530001A publication Critical patent/JP2010530001A/ja
Publication of JP2010530001A5 publication Critical patent/JP2010530001A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2010512395A 2007-06-15 2008-06-13 硫化物単独または一酸化窒素との組み合わせを含む組成物およびその使用 Pending JP2010530001A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94444407P 2007-06-15 2007-06-15
PCT/US2008/066973 WO2008157393A1 (en) 2007-06-15 2008-06-13 Compositions comprising sulfide alone or in combination with nitric oxide and their use to

Publications (2)

Publication Number Publication Date
JP2010530001A true JP2010530001A (ja) 2010-09-02
JP2010530001A5 JP2010530001A5 (enExample) 2011-07-28

Family

ID=39670390

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010512395A Pending JP2010530001A (ja) 2007-06-15 2008-06-13 硫化物単独または一酸化窒素との組み合わせを含む組成物およびその使用

Country Status (4)

Country Link
US (3) US20100247680A1 (enExample)
EP (1) EP2155213A1 (enExample)
JP (1) JP2010530001A (enExample)
WO (1) WO2008157393A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020531529A (ja) * 2017-08-25 2020-11-05 マリンクロット ホスピタル プロダクツ アイピー リミテッド 器官の生存率を改善する方法
JPWO2020262055A1 (enExample) * 2019-06-28 2020-12-30

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2605631A1 (en) * 2005-04-20 2006-10-26 Fred Hutchinson Cancer Research Center Methods, compositions and articles of manufacture for enhancing survivability of cells, tissues, organs, and organisms
JP5274248B2 (ja) 2005-05-27 2013-08-28 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル 酸化窒素治療及び医生物的応用のための酸化窒素放出粒子
US7923037B2 (en) 2006-10-05 2011-04-12 Ikaria, Inc. Liquid chalcogenide compositions and methods of manufacturing and using the same
US20100183748A1 (en) * 2009-01-21 2010-07-22 Ikaria, Inc. Methods for Treating or Preventing Radiocontrast Agent Induced Kidney Injury
US8541396B2 (en) 2009-04-24 2013-09-24 National University Of Singapore Morpholin-4-ium 4 methoxyphenyl (morpholino) phosphinodithioate (GYY4137) as a novel vasodilator agent
CN105214193B (zh) * 2009-05-27 2017-11-17 马林克罗特医疗产品知识产权公司 用于药物递送调节装置的分度药物收容装置组件及分度药物递送系统
DK2467173T3 (da) 2009-08-21 2019-07-29 Novan Inc Sårbandager, fremgangsmåder til anvendelse heraf og fremgangsmåder til dannelse deraf
ES2958410T3 (es) 2009-08-21 2024-02-08 Novan Inc Geles tópicos
US8591876B2 (en) 2010-12-15 2013-11-26 Novan, Inc. Methods of decreasing sebum production in the skin
WO2012118819A2 (en) 2011-02-28 2012-09-07 Novan, Inc. Nitric oxide-releasing s-nitrosothiol-modified silica particles and methods of making the same
MX386702B (es) 2014-02-10 2025-03-19 Fred Hutchinson Cancer Center Tratamiento con halogeno de ataque cardiaco y lesion isquemica.
TWI650326B (zh) 2017-10-24 2019-02-11 國立交通大學 醫藥組合物、化合物的用途及合成方法
JP6618976B2 (ja) * 2017-11-14 2019-12-11 イノ セラピューティクス エルエルシー 指標付弁と襟部を有する加圧容器組立体を係合するため、かつ薬物送達を調整するための装置と流体連通したプランジャ組立体により直線的に作動させるための装置および方法
CN111228223B (zh) * 2020-03-06 2021-06-18 同济大学 一种促进伤口愈合的聚合物囊泡及其制备方法和应用
CN114099419B (zh) * 2021-11-19 2023-03-24 苏州大学 一种载硫氢化钠可注射纳米纤维化水凝胶及其制备方法和应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006071957A1 (en) * 2004-12-23 2006-07-06 Sensormedics Corporation Device and method for treatment of wounds with nitric oxide

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69614024T2 (de) * 1995-04-20 2001-11-15 Clariant Finance (Bvi) Ltd., Tortola Stabile flüssige Schwefelfarbstoffsuspensionen und Verfahren zu deren Analyse
CA2430415A1 (en) * 2000-12-15 2002-06-20 Galileo Laboratories, Inc. Use of tocopherol, metabolites or derivatives thereof or flavonoid metabolites or derivatives thereof in the manufacture of a medicament for the treatment of tissue ischemia
PL375161A1 (en) * 2002-06-21 2005-11-28 University Of Pittsburgh Of The Commonwealth System Of Higher Education Pharmaceutical use of nitric oxide, heme oxygenase-1 and products of heme degradation
US20050136125A1 (en) * 2003-10-22 2005-06-23 Roth Mark B. Methods, compositions and devices for inducing stasis in cells, tissues, organs, and organisms
CA2646674A1 (en) * 2006-04-20 2007-11-01 Fred Hutchinson Cancer Research Center Use of chalcogenides for treating shock and other adverse conditions
MX2009003741A (es) * 2006-10-05 2009-07-10 Ikaria Inc Composiciones liquidas de calcogenuro y metodos para fabricar y utilizar las mismas.
US20100143503A1 (en) * 2006-12-22 2010-06-10 Ikaria, Inc. Combinations of nitric oxide and sulfide and methods of use and manufacture thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006071957A1 (en) * 2004-12-23 2006-07-06 Sensormedics Corporation Device and method for treatment of wounds with nitric oxide

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN5010007757; CAI: CARDIOVASCULAR RESEARCH V76 N1, 20070606, P29-40 *
JPN5010007758; KAWASAKI KOH: MOLECULAR AND CELLULAR BIOLOGY V23 N16, 200308, P5726-5737 *

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020531529A (ja) * 2017-08-25 2020-11-05 マリンクロット ホスピタル プロダクツ アイピー リミテッド 器官の生存率を改善する方法
JP2022140622A (ja) * 2017-08-25 2022-09-26 マリンクロット ホスピタル プロダクツ アイピー アンリミテッド カンパニー 器官の生存率を改善する方法
JP7249331B2 (ja) 2017-08-25 2023-03-30 マリンクロット ホスピタル プロダクツ アイピー アンリミテッド カンパニー 器官の生存率を改善する方法
US11950590B2 (en) 2017-08-25 2024-04-09 Mallinckrodt Pharmaceuticals Ireland Limited Methods to improve organ viability
US12285008B2 (en) 2017-08-25 2025-04-29 Mallinckrodt Pharmaceuticals Ireland Limited Methods to improve organ viability
JPWO2020262055A1 (enExample) * 2019-06-28 2020-12-30
WO2020262055A1 (ja) * 2019-06-28 2020-12-30 住友精化株式会社 創傷治療用ガス組成物及び創傷治療装置
JP7240687B2 (ja) 2019-06-28 2023-03-16 住友精化株式会社 創傷治療用ガス組成物及び創傷治療装置

Also Published As

Publication number Publication date
US20140220161A1 (en) 2014-08-07
US20100247680A1 (en) 2010-09-30
EP2155213A1 (en) 2010-02-24
WO2008157393A1 (en) 2008-12-24
US20170049809A1 (en) 2017-02-23

Similar Documents

Publication Publication Date Title
JP2010530001A (ja) 硫化物単独または一酸化窒素との組み合わせを含む組成物およびその使用
KR101538727B1 (ko) 액체 칼코게나이드 조성물 및 이의 제조방법과 사용방법
CN103547258B (zh) 局部一氧化氮系统及其使用方法
JP2009534422A (ja) ショックおよび他の有害な病態を処置するためのカルゴゲニドの使用
US8226986B2 (en) Liquid chalcogenide compositions and methods of manufacturing and using the same
US20140093588A1 (en) Combinations of nitric oxide and sulfide and methods of use and manufacture thereof
US20130252897A1 (en) Methods and Compositions Regarding Polychalcogenide Compositions
US11786712B2 (en) Nitric oxide-releasing device
US20240033301A1 (en) Approach to sustained production and delivery of nitric oxide and s-nitrosothiols
Getsy et al. D-cysteine ethyl ester and D-cystine dimethyl ester reverse the deleterious effects of morphine on arterial blood-gas chemistry and Alveolar-arterial gradient in anesthetized rats
Verma et al. A review of patents on therapeutic potential and delivery of hydroge n sulfide
CN101773517B (zh) H2s或h2s供体温度敏感性注射用即型凝胶制剂
BR102025001090A2 (pt) Método para preparar uma amostra de sangue com início tardio ou progressão retardada de lesão de armazenamento de hemácias ex vivo na amostra durante o armazenamento, amostra de sangue ex vivo, e método para transfusão de sangue
RU2274456C2 (ru) Ранозаживляющее средство
BR122025001904A2 (pt) Método para preparar uma amostra de sangue com início tardio ou progressão retardada de lesão de armazenamento de hemácias ex vivo na amostra durante o armazenamento, amostra de sangue ex vivo e seu uso
BRPI0705221B1 (pt) Dispositivos para a síntese e incorporação pré-aplicação de doadores de óxido nítrico em composições macromoleculares
BR112023008763B1 (pt) Formulação transdérmica, seus usos, método para melhorar a segurança e eficácia da transfusão, sistema de entrega transdérmico e kit
LT5486B (lt) Elementinės sieros vaistiniai produktai, skirti su glutationo s transferazės fermentu susijusioms ligoms gydyti

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110613

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20110613

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130517

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20130816

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20130823

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20140218