JP2010529205A5 - - Google Patents

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Publication number
JP2010529205A5
JP2010529205A5 JP2010512324A JP2010512324A JP2010529205A5 JP 2010529205 A5 JP2010529205 A5 JP 2010529205A5 JP 2010512324 A JP2010512324 A JP 2010512324A JP 2010512324 A JP2010512324 A JP 2010512324A JP 2010529205 A5 JP2010529205 A5 JP 2010529205A5
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JP
Japan
Prior art keywords
use according
therapeutic agent
pharmaceutical composition
calcium channel
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010512324A
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English (en)
Japanese (ja)
Other versions
JP5576790B2 (ja
JP2010529205A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/066576 external-priority patent/WO2008154585A1/en
Publication of JP2010529205A publication Critical patent/JP2010529205A/ja
Publication of JP2010529205A5 publication Critical patent/JP2010529205A5/ja
Application granted granted Critical
Publication of JP5576790B2 publication Critical patent/JP5576790B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2010512324A 2007-06-11 2008-06-11 脳血管れん縮の予防用薬物送達システム Expired - Fee Related JP5576790B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US94312407P 2007-06-11 2007-06-11
US60/943,124 2007-06-11
US97690207P 2007-10-29 2007-10-29
US60/976,902 2007-10-29
PCT/US2008/066576 WO2008154585A1 (en) 2007-06-11 2008-06-11 A drug delivery system for the prevention of cerebral vasospasm

Publications (3)

Publication Number Publication Date
JP2010529205A JP2010529205A (ja) 2010-08-26
JP2010529205A5 true JP2010529205A5 (https=) 2011-07-28
JP5576790B2 JP5576790B2 (ja) 2014-08-20

Family

ID=40096090

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010512324A Expired - Fee Related JP5576790B2 (ja) 2007-06-11 2008-06-11 脳血管れん縮の予防用薬物送達システム

Country Status (10)

Country Link
US (2) US8303974B2 (https=)
EP (1) EP2164497B1 (https=)
JP (1) JP5576790B2 (https=)
KR (3) KR101607244B1 (https=)
CN (3) CN101873858B (https=)
AU (1) AU2008261668C1 (https=)
CA (1) CA2690600C (https=)
IL (1) IL202647A (https=)
NZ (2) NZ581836A (https=)
WO (1) WO2008154585A1 (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8303974B2 (en) * 2007-06-11 2012-11-06 Edge Therapeutics, Inc. Drug delivery system for the prevention of cerebral vasospasm
US10092524B2 (en) 2008-06-11 2018-10-09 Edge Therapeutics, Inc. Compositions and their use to treat complications of aneurysmal subarachnoid hemorrhage
US8252302B2 (en) * 2007-06-11 2012-08-28 Edge Therapeutics, Inc. Methods and compositions to treat hemorrhagic conditions of the brain
EP2308478A1 (en) 2009-10-06 2011-04-13 Abbott GmbH & Co. KG Delivery system for sustained release of a calcium-channel blocking agent
EP2627173B2 (en) 2010-10-12 2018-07-04 Chiesi Farmaceutici S.p.A. Clevidipine emulsion formulations containing antimicrobial agents
US8658676B2 (en) * 2010-10-12 2014-02-25 The Medicines Company Clevidipine emulsion formulations containing antimicrobial agents
EP2672983B1 (en) * 2011-02-11 2017-04-19 Edge Therapeutics, Inc. Compositions and methods for improving prognosis of a human with subarachnoid hemorrhage
HK1198933A1 (en) * 2011-04-05 2015-06-19 Edge Therapeutics Intraventricular drug delivery system for improving outcome after a brain injury affecting cerebral blood flow
CN102416013A (zh) * 2011-12-30 2012-04-18 湖南九典制药有限公司 西尼地平的新用途
US9399019B2 (en) * 2012-05-09 2016-07-26 Evonik Corporation Polymorph compositions, methods of making, and uses thereof
WO2014165023A1 (en) 2013-03-12 2014-10-09 Carnegie Mellon University Coated vaso-occclusive device for treatment of aneurysms
CN103211812A (zh) * 2013-04-02 2013-07-24 苏州大学附属第一医院 Skf96365在治疗蛛网膜下腔出血后发生的脑血管痉挛的应用
US10403395B2 (en) * 2013-10-14 2019-09-03 SecondOpinionExpert, Inc. Method and apparatus for generating objective medical second opinion
CA2975447C (en) * 2015-01-30 2021-02-23 The Regents Of The University Of California Spinal subpial gene delivery system
KR20180021741A (ko) * 2015-05-29 2018-03-05 에쥐 세라피틱스, 인코포레이티드 시각 손실을 감소시키기 위한 조성물 및 방법
US10695400B2 (en) * 2015-08-03 2020-06-30 Enb Therapeutics, Inc. Compositions and methods for treating cancers associated with ETBR activation
AU2018300080B2 (en) 2017-07-11 2024-09-19 Sustained Nano Systems Llc Hypercompressed pharmaceutical formulations
AU2019206652B2 (en) 2018-01-12 2024-11-14 Enb Therapeutics, Inc. Deuterated compounds, compositions, and methods for treating cancers associated with ETBR activation
US20200163947A1 (en) * 2018-11-02 2020-05-28 Nortic Holdings Inc. Methods of treatment using nimodipine parenteral formulations
US11103142B2 (en) 2019-04-02 2021-08-31 Tencent America LLC System and method for predicting vertebral artery dissection
US20200315547A1 (en) * 2019-04-02 2020-10-08 Tencent America LLC Vertebral artery dissection risk evaluation method, computer device, and storage medium
JP7716076B2 (ja) * 2021-02-04 2025-07-31 学校法人産業医科大学 血管内穿孔によるくも膜下出血モデルの血腫を可視化する方法

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US5650489A (en) 1990-07-02 1997-07-22 The Arizona Board Of Regents Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
WO1995018972A1 (en) 1994-01-05 1995-07-13 Arqule, Inc. Systematic modular production of aminimide- and oxazolone-based molecules having selected properties
US5712171A (en) 1995-01-20 1998-01-27 Arqule, Inc. Method of generating a plurality of chemical compounds in a spatially arranged array
JP2909418B2 (ja) * 1995-09-18 1999-06-23 株式会社資生堂 薬物の遅延放出型マイクロスフイア
DE69735057T2 (de) 1996-03-12 2006-08-31 PG-TXL Co., L.P., Houston Wasserlösliche paclitaxel-prodrogen
US6123956A (en) 1997-07-10 2000-09-26 Keith Baker Methods for universally distributing therapeutic agents to the brain
US6284283B1 (en) * 1999-10-21 2001-09-04 Alkermes Controlled Therapeutics, Inc. Method of producing sub-micron particles of biologically active agents and uses thereof
JP2002003406A (ja) * 2000-06-21 2002-01-09 Sankyo Co Ltd 脳血管攣縮予防製剤
US20030032676A1 (en) * 2001-08-09 2003-02-13 Kimelberg Harold K. Drugs for treatment of cerebral injury and methods of use thereof
US20040224030A1 (en) * 2003-05-06 2004-11-11 Shastri Venkatram R. Microsphere delivery systems
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BRPI0414907A (pt) * 2003-09-30 2006-11-07 Acusphere Inc formulações farmacêuticas com liberação sustentada injetáveis, orais ou tópicas
US20060205733A1 (en) * 2004-08-26 2006-09-14 Encysive Pharmaceuticals Endothelin a receptor antagonists in combination with phosphodiesterase 5 inhibitors and uses thereof
WO2006084005A2 (en) * 2005-02-02 2006-08-10 University Of Vermont And State Agricultural College Emergence of a r-type ca2+channel(cav2.3) contributes to cerebral artery constriction following subarachnoid hemorrhage
US20060217340A1 (en) * 2005-03-23 2006-09-28 University Of Vermont And State Agricultural College Methods and products for treating hypertension by modulation of TRPC3 channel activity
US8303974B2 (en) * 2007-06-11 2012-11-06 Edge Therapeutics, Inc. Drug delivery system for the prevention of cerebral vasospasm

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