JP2010528261A5 - - Google Patents
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- Publication number
- JP2010528261A5 JP2010528261A5 JP2010507474A JP2010507474A JP2010528261A5 JP 2010528261 A5 JP2010528261 A5 JP 2010528261A5 JP 2010507474 A JP2010507474 A JP 2010507474A JP 2010507474 A JP2010507474 A JP 2010507474A JP 2010528261 A5 JP2010528261 A5 JP 2010528261A5
- Authority
- JP
- Japan
- Prior art keywords
- gpr110
- antibody
- level
- sample
- epitope
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 101000718228 Homo sapiens Adhesion G-protein coupled receptor F1 Proteins 0.000 claims 43
- 102100026443 Adhesion G-protein coupled receptor F1 Human genes 0.000 claims 39
- 238000000034 method Methods 0.000 claims 22
- 206010060862 Prostate cancer Diseases 0.000 claims 15
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 15
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 12
- 201000005202 lung cancer Diseases 0.000 claims 12
- 208000020816 lung neoplasm Diseases 0.000 claims 12
- 210000002307 prostate Anatomy 0.000 claims 12
- 210000004072 lung Anatomy 0.000 claims 10
- 210000004369 blood Anatomy 0.000 claims 7
- 239000008280 blood Substances 0.000 claims 7
- 210000002966 serum Anatomy 0.000 claims 7
- 108010072866 Prostate-Specific Antigen Proteins 0.000 claims 6
- 102000007066 Prostate-Specific Antigen Human genes 0.000 claims 6
- 238000001514 detection method Methods 0.000 claims 6
- 210000001124 body fluid Anatomy 0.000 claims 5
- 239000010839 body fluid Substances 0.000 claims 4
- 239000012634 fragment Substances 0.000 claims 4
- 102000055600 human ADGRF1 Human genes 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 238000012216 screening Methods 0.000 claims 4
- 210000001519 tissue Anatomy 0.000 claims 4
- 239000003550 marker Substances 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 102000010956 Glypican Human genes 0.000 claims 2
- 108050001154 Glypican Proteins 0.000 claims 2
- 102100032530 Glypican-3 Human genes 0.000 claims 2
- 108050007237 Glypican-3 Proteins 0.000 claims 2
- 125000000539 amino acid group Chemical group 0.000 claims 2
- 238000003556 assay Methods 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 238000003018 immunoassay Methods 0.000 claims 2
- 238000005259 measurement Methods 0.000 claims 2
- 239000007790 solid phase Substances 0.000 claims 2
- 229940124597 therapeutic agent Drugs 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 102000023732 binding proteins Human genes 0.000 claims 1
- 108091008324 binding proteins Proteins 0.000 claims 1
- 239000000090 biomarker Substances 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 230000003013 cytotoxicity Effects 0.000 claims 1
- 231100000135 cytotoxicity Toxicity 0.000 claims 1
- 230000003247 decreasing effect Effects 0.000 claims 1
- 230000001419 dependent effect Effects 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 230000035899 viability Effects 0.000 claims 1
- 230000000007 visual effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91671907P | 2007-05-08 | 2007-05-08 | |
| PCT/US2008/005983 WO2008140774A2 (en) | 2007-05-08 | 2008-05-08 | Methods for diagnosing and treating prostate and lung cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010528261A JP2010528261A (ja) | 2010-08-19 |
| JP2010528261A5 true JP2010528261A5 (https=) | 2011-08-25 |
Family
ID=40002842
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010507474A Pending JP2010528261A (ja) | 2007-05-08 | 2008-05-08 | 前立腺癌および肺癌の診断および治療方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20130224209A1 (https=) |
| EP (1) | EP2156184B1 (https=) |
| JP (1) | JP2010528261A (https=) |
| CN (1) | CN101918836B (https=) |
| AU (1) | AU2008251877A1 (https=) |
| CA (1) | CA2686954A1 (https=) |
| WO (1) | WO2008140774A2 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2152417B1 (en) | 2007-05-04 | 2018-07-11 | Opko Diagnostics, LLC | Device and method for analyses in microfluidic systems |
| US10236078B2 (en) | 2008-11-17 | 2019-03-19 | Veracyte, Inc. | Methods for processing or analyzing a sample of thyroid tissue |
| US8669057B2 (en) | 2009-05-07 | 2014-03-11 | Veracyte, Inc. | Methods and compositions for diagnosis of thyroid conditions |
| US20130209476A1 (en) * | 2010-06-04 | 2013-08-15 | The Brigham And Women's Hospital Inc. | Treatment of inflammatory disorders |
| JP5909070B2 (ja) * | 2010-10-28 | 2016-04-26 | 国立大学法人 東京大学 | Ｇｓ共役受容体に対する医薬品候補化合物をスクリーニングする方法 |
| TWI596494B (zh) * | 2012-03-05 | 2017-08-21 | Ｏｐｋｏ診斷法有限責任公司 | 預測前列腺癌風險及前列腺腺體體積之方法及裝置 |
| CN102914658A (zh) * | 2012-10-24 | 2013-02-06 | 高维强 | Crisp3蛋白在前列腺癌诊断和治疗中的应用 |
| US11976329B2 (en) | 2013-03-15 | 2024-05-07 | Veracyte, Inc. | Methods and systems for detecting usual interstitial pneumonia |
| KR102366820B1 (ko) * | 2014-01-17 | 2022-02-22 | 미노믹 인터내셔널 리미티드 | 진단을 위한 세포 표면 전립선암 항원 |
| CN104090103B (zh) * | 2014-03-24 | 2016-08-31 | 福州市传染病医院 | 基于抗体修饰ZnSe纳米晶检测肝癌标志物GPC3的试剂盒 |
| KR102505543B1 (ko) * | 2014-03-28 | 2023-03-02 | 옵코 다이어그노스틱스, 엘엘씨 | 전립선암 진단에 관한 조성물 및 방법 |
| US12326453B2 (en) | 2014-03-28 | 2025-06-10 | Opko Diagnostics, Llc | Compositions and methods for active surveillance of prostate cancer |
| EP2944652A1 (en) * | 2014-05-13 | 2015-11-18 | Technische Universität München | Glypican-3-specific T-cell receptors and their uses for immunotherapy of hepatocellular carcinoma |
| EP3169814B1 (en) * | 2014-07-14 | 2022-05-04 | Veracyte, Inc. | Methods for evaluating lung cancer status |
| US12297505B2 (en) | 2014-07-14 | 2025-05-13 | Veracyte, Inc. | Algorithms for disease diagnostics |
| EP3215170A4 (en) | 2014-11-05 | 2018-04-25 | Veracyte, Inc. | Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data |
| WO2016100301A1 (en) | 2014-12-15 | 2016-06-23 | The Brigham And Women's Hospital, Inc. | Use of cadherin-11 antagonists to treat obesity-associated conditions and other metabolic disorders |
| PT3253800T (pt) | 2015-03-27 | 2021-04-28 | Opko Diagnostics Llc | Padrões de antigénio da próstata e suas utilizações |
| CN112034185A (zh) * | 2020-09-11 | 2020-12-04 | 上海市胸科医院 | Gpr110、vegfr、cd34在鉴别肺腺癌亚型中的用途 |
| KR102730255B1 (ko) * | 2022-08-12 | 2024-11-15 | (주)맥시온 | 암 진단용 다중 바이오마커 및 이의 용도 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2795403B2 (ja) * | 1986-07-30 | 1998-09-10 | 株式会社 シノテスト | 免疫的測定方法及び装置 |
| WO2000009691A2 (en) * | 1998-08-10 | 2000-02-24 | Urogenesys, Inc. | Bpc-1: a secreted brain specific protein expressed and secreted by prostate and bladder cancer cells |
| WO2002077233A2 (en) * | 2000-11-08 | 2002-10-03 | Millennium Pharmaceuticals, Inc. | 38650, 28472, 5495, 65507, 81588 and 14354 METHODS AND COMPOSITIONS OF HUMAN PROTEINS AND USES THEREOF |
| CA2444691A1 (en) * | 2001-04-18 | 2002-10-31 | Protein Design Labs, Inc. | Methods of diagnosis of lung cancer, compositions and methods of screening for modulators of lung cancer |
| WO2003009814A2 (en) * | 2001-07-25 | 2003-02-06 | Millennium Pharmaceuticals, Inc. | Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of prostate cancer |
| AU2002330482A1 (en) * | 2002-09-04 | 2004-03-29 | Perseus Proteomics Inc. | Method of diagnosing cancer by detecting gpc3 |
| WO2006086578A1 (en) * | 2002-10-02 | 2006-08-17 | Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California | Internal biochemical sensing device |
| JP2004279157A (ja) * | 2003-03-14 | 2004-10-07 | Rohto Pharmaceut Co Ltd | 癌病巣判定のためのキット並びに方法 |
| US20060094046A1 (en) * | 2004-02-11 | 2006-05-04 | Arie Abo | Compositions and methods relating to angiogenesis and tumorigenesis |
| EP1723430A2 (fr) * | 2004-03-03 | 2006-11-22 | Biomerieux | Procede de detection de la forme libre activable du psa et son utilisation pour le diagnostic des pathologies benignes de la prostate et de l adenocarcinome de la prostate |
| MX2007006441A (es) * | 2004-11-30 | 2007-08-14 | Johnson & Johnson | Prognosis de cancer de pulmon. |
| US20060211059A1 (en) * | 2005-03-18 | 2006-09-21 | Taneja Samir S | Methods of improving screening, diagnosis and staging of prostate cancer using serum testosterone |
| JP2007075072A (ja) * | 2005-09-16 | 2007-03-29 | Satoshi Takahashi | プロサイモシンαの機能抑制用組成物を含む抗癌剤、およびプロサイモシンα遺伝子の発現抑制用組成物に含有される核酸 |
| CA2625403A1 (en) * | 2005-10-17 | 2007-04-26 | Institute For System Biology | Tissue-and serum-derived glycoproteins and methods of their use |
-
2008
- 2008-05-08 AU AU2008251877A patent/AU2008251877A1/en not_active Abandoned
- 2008-05-08 WO PCT/US2008/005983 patent/WO2008140774A2/en not_active Ceased
- 2008-05-08 EP EP20080754314 patent/EP2156184B1/en not_active Not-in-force
- 2008-05-08 CA CA 2686954 patent/CA2686954A1/en not_active Abandoned
- 2008-05-08 CN CN200880023852.5A patent/CN101918836B/zh not_active Expired - Fee Related
- 2008-05-08 JP JP2010507474A patent/JP2010528261A/ja active Pending
-
2013
- 2013-01-21 US US13/746,180 patent/US20130224209A1/en not_active Abandoned
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