JP2010526542A - インフルエンザの治療および予防 - Google Patents

インフルエンザの治療および予防 Download PDF

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Publication number
JP2010526542A
JP2010526542A JP2010507765A JP2010507765A JP2010526542A JP 2010526542 A JP2010526542 A JP 2010526542A JP 2010507765 A JP2010507765 A JP 2010507765A JP 2010507765 A JP2010507765 A JP 2010507765A JP 2010526542 A JP2010526542 A JP 2010526542A
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nucleic acid
influenza
seq
acid construct
cell
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Ceased
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JP2010507765A
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Japanese (ja)
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JP2010526542A5 (OSRAM
Inventor
ティモシー・ジェイムズ・ドーラン
ジェイムズ・クライミー・マッケイ
ロバート・ジョン・ムーア
ジョン・ウィリアム・ローエンタール
スコット・ジェフリー・タイヤック
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Commonwealth Scientific and Industrial Research Organization CSIRO
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Commonwealth Scientific and Industrial Research Organization CSIRO
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Priority claimed from AU2007902616A external-priority patent/AU2007902616A0/en
Application filed by Commonwealth Scientific and Industrial Research Organization CSIRO filed Critical Commonwealth Scientific and Industrial Research Organization CSIRO
Publication of JP2010526542A publication Critical patent/JP2010526542A/ja
Publication of JP2010526542A5 publication Critical patent/JP2010526542A5/ja
Ceased legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • A01K2217/054Animals comprising random inserted nucleic acids (transgenic) inducing loss of function
    • A01K2217/058Animals comprising random inserted nucleic acids (transgenic) inducing loss of function due to expression of inhibitory nucleic acid, e.g. siRNA, antisense
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/105Murine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/30Bird
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/03Animal model, e.g. for test or diseases
    • A01K2267/0337Animal models for infectious diseases
    • CCHEMISTRY; METALLURGY
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/11Antisense
    • C12N2310/111Antisense spanning the whole gene, or a large part of it
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering nucleic acids [NA]
    • CCHEMISTRY; METALLURGY
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/50Physical structure
    • C12N2310/53Physical structure partially self-complementary or closed
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2320/00Applications; Uses
    • C12N2320/10Applications; Uses in screening processes
    • C12N2320/11Applications; Uses in screening processes for the determination of target sites, i.e. of active nucleic acids
    • CCHEMISTRY; METALLURGY
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    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
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    • C12N2800/00Nucleic acids vectors
    • C12N2800/90Vectors containing a transposable element
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    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/38Vector systems having a special element relevant for transcription being a stuffer
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    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/80Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/90Vector systems having a special element relevant for transcription from vertebrates avian

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Environmental Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2010507765A 2007-05-16 2008-05-16 インフルエンザの治療および予防 Ceased JP2010526542A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US93831507P 2007-05-16 2007-05-16
AU2007902616A AU2007902616A0 (en) 2007-05-16 Treatment and prevention of influenza
PCT/AU2008/000692 WO2008138072A1 (en) 2007-05-16 2008-05-16 Treatment and prevention of influenza

Publications (2)

Publication Number Publication Date
JP2010526542A true JP2010526542A (ja) 2010-08-05
JP2010526542A5 JP2010526542A5 (OSRAM) 2011-06-30

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JP2010507765A Ceased JP2010526542A (ja) 2007-05-16 2008-05-16 インフルエンザの治療および予防

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Country Link
US (1) US20110209231A1 (OSRAM)
EP (2) EP2160466A4 (OSRAM)
JP (1) JP2010526542A (OSRAM)
KR (1) KR20100028038A (OSRAM)
CN (1) CN101918558B (OSRAM)
AU (1) AU2008250973B2 (OSRAM)
BR (1) BRPI0811870A2 (OSRAM)
CA (1) CA2687115A1 (OSRAM)
CO (1) CO6251333A2 (OSRAM)
EA (1) EA017948B1 (OSRAM)
IL (1) IL202126A (OSRAM)
MX (1) MX2009012317A (OSRAM)
MY (1) MY149171A (OSRAM)
NZ (2) NZ597601A (OSRAM)
WO (1) WO2008138072A1 (OSRAM)
ZA (1) ZA200908100B (OSRAM)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015514404A (ja) * 2012-04-20 2015-05-21 コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガナイゼーション 細胞トランスフェクション法
US10050301B2 (en) 2014-01-13 2018-08-14 Lg Chem, Ltd. Battery cell including electrode assembly coated with inert particles

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BR112012000565A2 (pt) * 2009-06-19 2016-11-16 Commw Scient Ind Res Org ensaio de vírus.
RU2599449C1 (ru) * 2011-12-15 2016-10-10 Байонир Корпорейшн Новые конъюгаты олигонуклеотидов и их применение
CN103966212A (zh) * 2013-02-06 2014-08-06 霍晋 A型流感病毒NP基因有干扰作用的siRNA序列的设计及应用
ES2796930T3 (es) * 2014-01-23 2020-11-30 Univ Colorado State Res Found Silenciamiento de ARNip mediado por E. coli de la gripe aviar en pollos
KR20160076952A (ko) 2014-12-23 2016-07-01 김규리 문자 편집 장치 및 방법
AU2016305490B2 (en) 2015-08-07 2022-07-14 Commonwealth Scientific And Industrial Research Organisation Method for producing an animal comprising a germline genetic modification
WO2018187381A2 (en) 2017-04-03 2018-10-11 Sivec Biotechnologies, Llc A transkingdom platform for therapeutic nucleic acid delivery
CN109966497B (zh) * 2019-04-08 2021-03-12 中国医学科学院医药生物技术研究所 以ipan或其编码基因为靶点的物质在制备流感病毒抑制剂中的应用
CN111084154A (zh) * 2019-12-30 2020-05-01 集美大学 一种蛙类多层养殖装置
KR102584623B1 (ko) * 2023-03-08 2023-10-06 대한민국 오리 유래 rna 폴리머라제 i 프로모터 및 이를 포함하는 재조합 벡터

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015514404A (ja) * 2012-04-20 2015-05-21 コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガナイゼーション 細胞トランスフェクション法
US10050301B2 (en) 2014-01-13 2018-08-14 Lg Chem, Ltd. Battery cell including electrode assembly coated with inert particles

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US20110209231A1 (en) 2011-08-25
KR20100028038A (ko) 2010-03-11
NZ597601A (en) 2013-04-26
CO6251333A2 (es) 2011-02-21
AU2008250973B2 (en) 2012-10-11
CA2687115A1 (en) 2008-11-20
CN101918558A (zh) 2010-12-15
MX2009012317A (es) 2010-04-01
AU2008250973A1 (en) 2008-11-20
EA017948B1 (ru) 2013-04-30
EP2160466A1 (en) 2010-03-10
MY149171A (en) 2013-07-31
BRPI0811870A2 (pt) 2014-10-21
IL202126A0 (en) 2011-08-01
EP2160466A4 (en) 2011-07-13
EP2527445A3 (en) 2013-02-20
IL202126A (en) 2015-10-29
EP2527445A2 (en) 2012-11-28
CN101918558B (zh) 2016-12-07
ZA200908100B (en) 2012-01-25
WO2008138072A1 (en) 2008-11-20
NZ581542A (en) 2012-02-24
EA200971059A1 (ru) 2010-04-30

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