JP2010523671A5 - - Google Patents

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Publication number
JP2010523671A5
JP2010523671A5 JP2010503048A JP2010503048A JP2010523671A5 JP 2010523671 A5 JP2010523671 A5 JP 2010523671A5 JP 2010503048 A JP2010503048 A JP 2010503048A JP 2010503048 A JP2010503048 A JP 2010503048A JP 2010523671 A5 JP2010523671 A5 JP 2010523671A5
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JP
Japan
Prior art keywords
pth
polypeptide fragment
collagen
binding polypeptide
receptor agonist
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2010503048A
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English (en)
Japanese (ja)
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JP2010523671A (ja
JP5520811B2 (ja
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Publication date
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Priority claimed from PCT/US2008/004589 external-priority patent/WO2008124166A2/en
Publication of JP2010523671A publication Critical patent/JP2010523671A/ja
Publication of JP2010523671A5 publication Critical patent/JP2010523671A5/ja
Application granted granted Critical
Publication of JP5520811B2 publication Critical patent/JP5520811B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2010503048A 2007-04-09 2008-04-09 コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク Active JP5520811B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92243307P 2007-04-09 2007-04-09
US60/922,433 2007-04-09
PCT/US2008/004589 WO2008124166A2 (en) 2007-04-09 2008-04-09 Fusion proteins of collagen-binding domain and parathyroid hormone

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013194484A Division JP5821066B2 (ja) 2007-04-09 2013-09-19 コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク

Publications (3)

Publication Number Publication Date
JP2010523671A JP2010523671A (ja) 2010-07-15
JP2010523671A5 true JP2010523671A5 (https=) 2011-05-26
JP5520811B2 JP5520811B2 (ja) 2014-06-11

Family

ID=39831527

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2010503048A Active JP5520811B2 (ja) 2007-04-09 2008-04-09 コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク
JP2013194484A Active JP5821066B2 (ja) 2007-04-09 2013-09-19 コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク
JP2015173678A Active JP5989876B2 (ja) 2007-04-09 2015-09-03 コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク
JP2016157345A Active JP6366653B2 (ja) 2007-04-09 2016-08-10 コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2013194484A Active JP5821066B2 (ja) 2007-04-09 2013-09-19 コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク
JP2015173678A Active JP5989876B2 (ja) 2007-04-09 2015-09-03 コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク
JP2016157345A Active JP6366653B2 (ja) 2007-04-09 2016-08-10 コラーゲン結合領域と副甲状腺ホルモンとの融合タンパク

Country Status (7)

Country Link
US (6) US8450273B2 (https=)
EP (2) EP2155874B1 (https=)
JP (4) JP5520811B2 (https=)
CA (2) CA2930681C (https=)
DK (2) DK2155874T3 (https=)
ES (2) ES2675174T3 (https=)
WO (1) WO2008124166A2 (https=)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008124166A2 (en) * 2007-04-09 2008-10-16 The Board Of Trustees Of The University Of Arkansas Fusion proteins of collagen-binding domain and parathyroid hormone
ES2531402T3 (es) * 2008-11-19 2015-03-13 Meiji Seika Pharma Co Ltd Colagenasa de fusión a la que se une una marca de afinidad, y método para producir la misma
EP2405008A1 (en) * 2010-07-06 2012-01-11 LanthioPep B.V. Bacterial surface display of thioether-bridge-containing peptides
US9173919B2 (en) 2011-02-16 2015-11-03 Purdue Research Foundation Collagen-targeted nanoparticles
EP2708246B1 (en) * 2011-05-13 2017-11-01 School Juridical Person Kitasato Institute Growth factor anchoring type bone graft material, method for producing growth factor anchoring type bone graft material, kit for producing growth factor anchoring type bone graft material.
ES2695161T3 (es) * 2011-12-14 2019-01-02 Univ Arkansas Administración de agentes terapéuticos mediante una proteína de unión a colágeno
WO2013120060A1 (en) 2012-02-09 2013-08-15 The Board Of Trustees Of The University Of Arkansas Delivery of therapeutic agents by a collagen binding protein
US8969290B2 (en) * 2012-06-26 2015-03-03 Worcester Polytechnic Institute Matrix scaffold with antimicrobial activity
WO2016085280A1 (ko) 2014-11-28 2016-06-02 서울대학교산학협력단 세포 투과성 스테이플 펩타이드, 이의 제조방법 및 그 용도
WO2016197491A1 (en) 2015-06-12 2016-12-15 Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences A three-dimensional tissue scaffold with stem cell attracting element and use thereof
MX2018009938A (es) 2016-03-01 2019-03-14 Ascendis Pharma Bone Diseases As Profarmacos de hormona paratiroidea (pth).
CN109789189B (zh) 2016-09-29 2024-01-23 阿森迪斯药物骨疾病股份有限公司 控释pth化合物的剂量方案
MA46428B1 (fr) 2016-09-29 2025-02-28 Ascendis Pharma Bone Diseases A/S Composés de pth à libération contrôlée
EP3518961B1 (en) 2016-09-29 2023-02-22 Ascendis Pharma Bone Diseases A/S Pth compounds with low peak-to-trough ratios
WO2018102616A1 (en) * 2016-11-30 2018-06-07 Purdue Research Foundation Fracture targeted bone regeneration through parathyroid hormone receptor stimulation
US11624060B2 (en) 2017-02-10 2023-04-11 The Board Of Trustees Of The University Of Arkansas Collagen-binding agent compositions and methods of using the same
GB201706781D0 (en) 2017-04-28 2017-06-14 Univ Sheffield Parathyroid hormone fusion polypeptide
CN107213517B (zh) * 2017-05-17 2020-03-27 宁波大学 一种复合骨水泥及其制备方法
JP6577683B2 (ja) * 2017-09-22 2019-09-18 旭化成ファーマ株式会社 安定性に優れるテリパラチド含有液状医薬組成物
KR101964376B1 (ko) * 2017-09-29 2019-04-01 주식회사 나이벡 부갑상선호르몬(parathyroid hormone, PTH)에 골조직 선택성 펩타이드가 결합되어 있는 융합 펩타이드를 포함하는 약학 조성물 및 생체재료
WO2019232285A1 (en) 2018-05-30 2019-12-05 Purdue Research Foundation Targeting anabolic drugs for accelerated fracture repair
CA3129357A1 (en) 2019-02-11 2020-08-20 Ascendis Pharma Bone Diseases A/S Liquid pharmaceutical formulations of pth conjugates
US20220289812A1 (en) * 2019-08-09 2022-09-15 Phasebio Pharmaceuticals, Inc. Elp fusion proteins comprising parathyroid hormone for controlled and sustained release
US12403179B2 (en) 2021-02-18 2025-09-02 The Board Of Trustees Of The University Of Arkansas Release of growth factors at wound healing stages
EP4593867A2 (en) 2022-09-30 2025-08-06 Extend Biosciences, Inc. Long-acting parathyroid hormone

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8516421D0 (en) 1985-06-28 1985-07-31 Biotechnology Interface Ltd Fibronectins
ATE209887T1 (de) 1993-04-02 2001-12-15 Anticancer Inc Verfahren zur verabreichung von förderlichen zusammensetzungen auf die haarfollikel
US5925552A (en) 1996-04-25 1999-07-20 Medtronic, Inc. Method for attachment of biomolecules to medical devices surfaces
DE69734157T2 (de) 1996-07-31 2006-07-13 The General Hospital Corp., Boston Parathyroidhormon-verwandthe peptidanaloge
US6428579B1 (en) 1998-07-01 2002-08-06 Brown University Research Foundation Implantable prosthetic devices coated with bioactive molecules
US6387663B1 (en) 1998-07-31 2002-05-14 University Of Southern California Targeting pharmaceutical agents to injured tissues
US7601685B2 (en) 1998-08-27 2009-10-13 Eidgenossische Technische Hochschule Zurich Growth factor modified protein matrices for tissue engineering
EP1151116A1 (en) 1999-02-19 2001-11-07 Terumo Kabushiki Kaisha Collagen-binding physiologically active polypeptide
JP2001190280A (ja) * 1999-02-19 2001-07-17 Terumo Corp コラーゲン結合性生理活性ポリペプチド
US20020102709A1 (en) * 1999-02-19 2002-08-01 Tetsuya Ishikawa Collagen-binding physiologically active polypeptide
US6908994B1 (en) 1999-05-10 2005-06-21 The Texas A&M University System Collagen-binding proteins from enterococcal bacteria
US20050124537A1 (en) 2000-04-27 2005-06-09 Amgen Inc. Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
EP1314780A4 (en) * 2000-08-15 2004-07-28 Terumo Corp Collagen-binding hybrid polypeptides
JP2002058485A (ja) 2000-08-16 2002-02-26 Terumo Corp コラーゲン結合性を有する骨形成促進融合蛋白質
US20020063621A1 (en) 2000-09-01 2002-05-30 Next Planet, Inc. Method and apparatus for device communications
US6812217B2 (en) 2000-12-04 2004-11-02 Medtronic, Inc. Medical device and methods of use
MXPA04006021A (es) 2001-12-18 2005-08-19 Eth Zuerich Matrices de proteina modificada con factor de crecimiento para ingenieria de tejidos.
WO2004011484A2 (en) 2002-07-25 2004-02-05 The General Hospital Corporation Parathyroid hormone receptor activation and hematopoietic progenitor cell expansion
US7060299B2 (en) 2002-12-31 2006-06-13 Battelle Memorial Institute Biodegradable microparticles that stabilize and control the release of proteins
ATE336270T1 (de) 2003-02-13 2006-09-15 Synthes Ag Injizierbare knochenersatzmischung
US20040220094A1 (en) 2003-05-01 2004-11-04 Skinner Keith K. Inverse agonist and agonist peptides that stimulate/inhibit hair growth
EP1680073B1 (en) 2003-10-21 2013-01-02 IGF Oncology, LLC Compounds and method for treating cancer
US20050119183A1 (en) * 2003-11-12 2005-06-02 Nps Allelix Corp. Method for treating bone loss using parathyroid hormone
EP1557176A1 (en) * 2004-01-26 2005-07-27 Ferring B.V. Treatment of bone metastases by means of PTH receptor agonists
US20090005298A1 (en) 2004-02-27 2009-01-01 The University Of Western Ontario Bone Sialoprotein Collagen-Binding Peptides
DE602005027461D1 (de) 2004-04-21 2011-05-26 Enobia Pharma Inc Konjugate zur zuführung an knochen und verfahren zu deren verwendung beim hinführen von proteinen zum knochen
CA2582552A1 (en) 2004-10-21 2006-05-04 Igf Oncology, Llc Toxins and radionuclides coupled to igf-1 receptor ligands for treatment of cancer
WO2006073711A2 (en) * 2005-01-06 2006-07-13 Kuros Biosurgery Ag Use of a matrix comprising a contrast agent in soft tissues
ATE514712T1 (de) 2005-12-26 2011-07-15 Yantai Zhenghai Bio Technology Co Ltd Aktivierte collagen-gerüstmaterialien und ihre speziellen kondensierten aktiven restorationsfaktoren
WO2008124166A2 (en) 2007-04-09 2008-10-16 The Board Of Trustees Of The University Of Arkansas Fusion proteins of collagen-binding domain and parathyroid hormone
JP2010172247A (ja) 2009-01-29 2010-08-12 Kitasato Institute 積層型高密度培養人工組織の製造方法及び積層型高密度培養人工組織
JPWO2011142425A1 (ja) 2010-05-12 2013-07-22 国立大学法人 香川大学 上皮層含有組織の再生材および再生評価方法
EP2708246B1 (en) 2011-05-13 2017-11-01 School Juridical Person Kitasato Institute Growth factor anchoring type bone graft material, method for producing growth factor anchoring type bone graft material, kit for producing growth factor anchoring type bone graft material.
ES2695161T3 (es) 2011-12-14 2019-01-02 Univ Arkansas Administración de agentes terapéuticos mediante una proteína de unión a colágeno
WO2013120060A1 (en) 2012-02-09 2013-08-15 The Board Of Trustees Of The University Of Arkansas Delivery of therapeutic agents by a collagen binding protein

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